Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50031992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322858 ((R)-3-phenyl-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-e...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-23(22-39-17-5-6-18-39)25-15-16-29-26(19-25)11-7-14-30(29)37-32(40)21-31(24-9-3-2-4-10-24)38-43(41,42)28-13-8-12-27(20-28)33(34,35)36/h2-4,8-10,12-13,15-16,19-20,30-31,38H,1,5-7,11,14,17-18,21-22H2,(H,37,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322857 ((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C34H38F3N3O3S/c1-24(23-40-18-6-3-7-19-40)26-16-17-30-27(20-26)12-8-15-31(30)38-33(41)22-32(25-10-4-2-5-11-25)39-44(42,43)29-14-9-13-28(21-29)34(35,36)37/h2,4-5,9-11,13-14,16-17,20-21,31-32,39H,1,3,6-8,12,15,18-19,22-23H2,(H,38,41)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322868 ((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-22(21-37-27-12-7-13-27)24-16-17-29-25(18-24)10-5-15-30(29)38-32(40)20-31(23-8-3-2-4-9-23)39-43(41,42)28-14-6-11-26(19-28)33(34,35)36/h2-4,6,8-9,11,14,16-19,27,30-31,37,39H,1,5,7,10,12-13,15,20-21H2,(H,38,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322859 ((R)-N-((R)-6-(3-((S)-3-hydroxypyrrolidin-1-yl)prop...) Show SMILES O[C@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1 |r| Show InChI InChI=1S/C33H36F3N3O4S/c1-22(20-39-16-15-27(40)21-39)24-13-14-29-25(17-24)9-5-12-30(29)37-32(41)19-31(23-7-3-2-4-8-23)38-44(42,43)28-11-6-10-26(18-28)33(34,35)36/h2-4,6-8,10-11,13-14,17-18,27,30-31,38,40H,1,5,9,12,15-16,19-21H2,(H,37,41)/t27-,30+,31+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322867 ((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...) Show SMILES CC(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C32H36F3N3O3S/c1-21(2)36-20-22(3)24-15-16-28-25(17-24)11-7-14-29(28)37-31(39)19-30(23-9-5-4-6-10-23)38-42(40,41)27-13-8-12-26(18-27)32(33,34)35/h4-6,8-10,12-13,15-18,21,29-30,36,38H,3,7,11,14,19-20H2,1-2H3,(H,37,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322866 ((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...) Show SMILES CC(C)(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C33H38F3N3O3S/c1-22(21-37-32(2,3)4)24-16-17-28-25(18-24)12-8-15-29(28)38-31(40)20-30(23-10-6-5-7-11-23)39-43(41,42)27-14-9-13-26(19-27)33(34,35)36/h5-7,9-11,13-14,16-19,29-30,37,39H,1,8,12,15,20-21H2,2-4H3,(H,38,40)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322861 ((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C32H34F3N3O3S/c1-22(21-38-16-7-17-38)24-14-15-28-25(18-24)10-5-13-29(28)36-31(39)20-30(23-8-3-2-4-9-23)37-42(40,41)27-12-6-11-26(19-27)32(33,34)35/h2-4,6,8-9,11-12,14-15,18-19,29-30,37H,1,5,7,10,13,16-17,20-21H2,(H,36,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322860 ((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...) Show SMILES O[C@@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1 |r| Show InChI InChI=1S/C33H36F3N3O4S/c1-22(20-39-16-15-27(40)21-39)24-13-14-29-25(17-24)9-5-12-30(29)37-32(41)19-31(23-7-3-2-4-8-23)38-44(42,43)28-11-6-10-26(18-28)33(34,35)36/h2-4,6-8,10-11,13-14,17-18,27,30-31,38,40H,1,5,9,12,15-16,19-21H2,(H,37,41)/t27-,30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322856 ((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C1(CN2CCCCC2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H40F3N3O3S/c36-35(37,38)28-12-8-13-29(22-28)45(43,44)40-32(25-9-3-1-4-10-25)23-33(42)39-31-14-7-11-26-21-27(15-16-30(26)31)34(17-18-34)24-41-19-5-2-6-20-41/h1,3-4,8-10,12-13,15-16,21-22,31-32,40H,2,5-7,11,14,17-20,23-24H2,(H,39,42)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322865 ((R)-N-((R)-6-(3-(cyclopropylmethylamino)prop-1-en-...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNCC1CC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-22(20-37-21-23-13-14-23)25-15-16-29-26(17-25)9-5-12-30(29)38-32(40)19-31(24-7-3-2-4-8-24)39-43(41,42)28-11-6-10-27(18-28)33(34,35)36/h2-4,6-8,10-11,15-18,23,30-31,37,39H,1,5,9,12-14,19-21H2,(H,38,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322863 ((R)-N-((R)-6-(3-(2-hydroxyethylamino)prop-1-en-2-y...) Show SMILES OCCNCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C31H34F3N3O4S/c1-21(20-35-15-16-38)23-13-14-27-24(17-23)9-5-12-28(27)36-30(39)19-29(22-7-3-2-4-8-22)37-42(40,41)26-11-6-10-25(18-26)31(32,33)34/h2-4,6-8,10-11,13-14,17-18,28-29,35,37-38H,1,5,9,12,15-16,19-20H2,(H,36,39)/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322869 ((R)-N-((R)-6-(3-(cyclopentylamino)prop-1-en-2-yl)-...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCCC1)c1ccccc1 |r| Show InChI InChI=1S/C34H38F3N3O3S/c1-23(22-38-28-13-5-6-14-28)25-17-18-30-26(19-25)11-7-16-31(30)39-33(41)21-32(24-9-3-2-4-10-24)40-44(42,43)29-15-8-12-27(20-29)34(35,36)37/h2-4,8-10,12,15,17-20,28,31-32,38,40H,1,5-7,11,13-14,16,21-22H2,(H,39,41)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322855 ((3R)-3-phenyl-N-((1R)-6-(1-(piperidin-1-yl)propan-...) Show SMILES CC(CN1CCCCC1)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C34H40F3N3O3S/c1-24(23-40-18-6-3-7-19-40)26-16-17-30-27(20-26)12-8-15-31(30)38-33(41)22-32(25-10-4-2-5-11-25)39-44(42,43)29-14-9-13-28(21-29)34(35,36)37/h2,4-5,9-11,13-14,16-17,20-21,24,31-32,39H,3,6-8,12,15,18-19,22-23H2,1H3,(H,38,41)/t24?,31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322864 ((R)-N-((R)-6-(3-(2-methoxyethylamino)prop-1-en-2-y...) Show SMILES COCCNCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C32H36F3N3O4S/c1-22(21-36-16-17-42-2)24-14-15-28-25(18-24)10-6-13-29(28)37-31(39)20-30(23-8-4-3-5-9-23)38-43(40,41)27-12-7-11-26(19-27)32(33,34)35/h3-5,7-9,11-12,14-15,18-19,29-30,36,38H,1,6,10,13,16-17,20-21H2,2H3,(H,37,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322862 ((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...) Show SMILES CN(C)CC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C31H34F3N3O3S/c1-21(20-37(2)3)23-15-16-27-24(17-23)11-7-14-28(27)35-30(38)19-29(22-9-5-4-6-10-22)36-41(39,40)26-13-8-12-25(18-26)31(32,33)34/h4-6,8-10,12-13,15-18,28-29,36H,1,7,11,14,19-20H2,2-3H3,(H,35,38)/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322870 ((R)-3-(4-fluorophenyl)-N-((R)-6-(3-(pyrrolidin-1-y...) Show SMILES Fc1ccc(cc1)[C@@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCC1)NS(=O)(=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C33H35F4N3O3S/c1-22(21-40-16-2-3-17-40)24-12-15-29-25(18-24)6-4-9-30(29)38-32(41)20-31(23-10-13-27(34)14-11-23)39-44(42,43)28-8-5-7-26(19-28)33(35,36)37/h5,7-8,10-15,18-19,30-31,39H,1-4,6,9,16-17,20-21H2,(H,38,41)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322859 ((R)-N-((R)-6-(3-((S)-3-hydroxypyrrolidin-1-yl)prop...) Show SMILES O[C@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1 |r| Show InChI InChI=1S/C33H36F3N3O4S/c1-22(20-39-16-15-27(40)21-39)24-13-14-29-25(17-24)9-5-12-30(29)37-32(41)19-31(23-7-3-2-4-8-23)38-44(42,43)28-11-6-10-26(18-28)33(34,35)36/h2-4,6-8,10-11,13-14,17-18,27,30-31,38,40H,1,5,9,12,15-16,19-21H2,(H,37,41)/t27-,30+,31+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322858 ((R)-3-phenyl-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-e...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-23(22-39-17-5-6-18-39)25-15-16-29-26(19-25)11-7-14-30(29)37-32(40)21-31(24-9-3-2-4-10-24)38-43(41,42)28-13-8-12-27(20-28)33(34,35)36/h2-4,8-10,12-13,15-16,19-20,30-31,38H,1,5-7,11,14,17-18,21-22H2,(H,37,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322860 ((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...) Show SMILES O[C@@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1 |r| Show InChI InChI=1S/C33H36F3N3O4S/c1-22(20-39-16-15-27(40)21-39)24-13-14-29-25(17-24)9-5-12-30(29)37-32(41)19-31(23-7-3-2-4-8-23)38-44(42,43)28-11-6-10-26(18-28)33(34,35)36/h2-4,6-8,10-11,13-14,17-18,27,30-31,38,40H,1,5,9,12,15-16,19-21H2,(H,37,41)/t27-,30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322864 ((R)-N-((R)-6-(3-(2-methoxyethylamino)prop-1-en-2-y...) Show SMILES COCCNCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C32H36F3N3O4S/c1-22(21-36-16-17-42-2)24-14-15-28-25(18-24)10-6-13-29(28)37-31(39)20-30(23-8-4-3-5-9-23)38-43(40,41)27-12-7-11-26(19-27)32(33,34)35/h3-5,7-9,11-12,14-15,18-19,29-30,36,38H,1,6,10,13,16-17,20-21H2,2H3,(H,37,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322863 ((R)-N-((R)-6-(3-(2-hydroxyethylamino)prop-1-en-2-y...) Show SMILES OCCNCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C31H34F3N3O4S/c1-21(20-35-15-16-38)23-13-14-27-24(17-23)9-5-12-28(27)36-30(39)19-29(22-7-3-2-4-8-22)37-42(40,41)26-11-6-10-25(18-26)31(32,33)34/h2-4,6-8,10-11,13-14,17-18,28-29,35,37-38H,1,5,9,12,15-16,19-20H2,(H,36,39)/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322857 ((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C34H38F3N3O3S/c1-24(23-40-18-6-3-7-19-40)26-16-17-30-27(20-26)12-8-15-31(30)38-33(41)22-32(25-10-4-2-5-11-25)39-44(42,43)29-14-9-13-28(21-29)34(35,36)37/h2,4-5,9-11,13-14,16-17,20-21,31-32,39H,1,3,6-8,12,15,18-19,22-23H2,(H,38,41)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322867 ((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...) Show SMILES CC(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C32H36F3N3O3S/c1-21(2)36-20-22(3)24-15-16-28-25(17-24)11-7-14-29(28)37-31(39)19-30(23-9-5-4-6-10-23)38-42(40,41)27-13-8-12-26(18-27)32(33,34)35/h4-6,8-10,12-13,15-18,21,29-30,36,38H,3,7,11,14,19-20H2,1-2H3,(H,37,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322868 ((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-22(21-37-27-12-7-13-27)24-16-17-29-25(18-24)10-5-15-30(29)38-32(40)20-31(23-8-3-2-4-9-23)39-43(41,42)28-14-6-11-26(19-28)33(34,35)36/h2-4,6,8-9,11,14,16-19,27,30-31,37,39H,1,5,7,10,12-13,15,20-21H2,(H,38,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322869 ((R)-N-((R)-6-(3-(cyclopentylamino)prop-1-en-2-yl)-...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCCC1)c1ccccc1 |r| Show InChI InChI=1S/C34H38F3N3O3S/c1-23(22-38-28-13-5-6-14-28)25-17-18-30-26(19-25)11-7-16-31(30)39-33(41)21-32(24-9-3-2-4-10-24)40-44(42,43)29-15-8-12-27(20-29)34(35,36)37/h2-4,8-10,12,15,17-20,28,31-32,38,40H,1,5-7,11,13-14,16,21-22H2,(H,39,41)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322866 ((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...) Show SMILES CC(C)(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C33H38F3N3O3S/c1-22(21-37-32(2,3)4)24-16-17-28-25(18-24)12-8-15-29(28)38-31(40)20-30(23-10-6-5-7-11-23)39-43(41,42)27-14-9-13-26(19-27)33(34,35)36/h5-7,9-11,13-14,16-19,29-30,37,39H,1,8,12,15,20-21H2,2-4H3,(H,38,40)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322856 ((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C1(CN2CCCCC2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H40F3N3O3S/c36-35(37,38)28-12-8-13-29(22-28)45(43,44)40-32(25-9-3-1-4-10-25)23-33(42)39-31-14-7-11-26-21-27(15-16-30(26)31)34(17-18-34)24-41-19-5-2-6-20-41/h1,3-4,8-10,12-13,15-16,21-22,31-32,40H,2,5-7,11,14,17-20,23-24H2,(H,39,42)/t31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322865 ((R)-N-((R)-6-(3-(cyclopropylmethylamino)prop-1-en-...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNCC1CC1)c1ccccc1 |r| Show InChI InChI=1S/C33H36F3N3O3S/c1-22(20-37-21-23-13-14-23)25-15-16-29-26(17-25)9-5-12-30(29)38-32(40)19-31(24-7-3-2-4-8-24)39-43(41,42)28-11-6-10-27(18-28)33(34,35)36/h2-4,6-8,10-11,15-18,23,30-31,37,39H,1,5,9,12-14,19-21H2,(H,38,40)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322862 ((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...) Show SMILES CN(C)CC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C31H34F3N3O3S/c1-21(20-37(2)3)23-15-16-27-24(17-23)11-7-14-28(27)35-30(38)19-29(22-9-5-4-6-10-22)36-41(39,40)26-13-8-12-25(18-26)31(32,33)34/h4-6,8-10,12-13,15-18,28-29,36H,1,7,11,14,19-20H2,2-3H3,(H,35,38)/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322861 ((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCC1)c1ccccc1 |r| Show InChI InChI=1S/C32H34F3N3O3S/c1-22(21-38-16-7-17-38)24-14-15-28-25(18-24)10-5-13-29(28)36-31(39)20-30(23-8-3-2-4-9-23)37-42(40,41)27-12-6-11-26(19-27)32(33,34)35/h2-4,6,8-9,11-12,14-15,18-19,29-30,37H,1,5,7,10,13,16-17,20-21H2,(H,36,39)/t29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322855 ((3R)-3-phenyl-N-((1R)-6-(1-(piperidin-1-yl)propan-...) Show SMILES CC(CN1CCCCC1)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C34H40F3N3O3S/c1-24(23-40-18-6-3-7-19-40)26-16-17-30-27(20-26)12-8-15-31(30)38-33(41)22-32(25-10-4-2-5-11-25)39-44(42,43)29-14-9-13-28(21-29)34(35,36)37/h2,4-5,9-11,13-14,16-17,20-21,24,31-32,39H,3,6-8,12,15,18-19,22-23H2,1H3,(H,38,41)/t24?,31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair