Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbapenem-hydrolyzing beta-lactamase KPC (Klebsiella pneumoniae) | BDBM50053173 ((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Service de Bactériologie-Virologie, Hôpital de Bicêtre Curated by ChEMBL | Assay Description Inhibition of carbapenem-resistant Klebsiella pneumoniae carbepenem-hydrolyzing beta-lactamase KPC-1 | Antimicrob Agents Chemother 54: 328-32 (2009) Article DOI: 10.1128/AAC.00961-09 BindingDB Entry DOI: 10.7270/Q2ZW1M3F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbapenem-hydrolyzing beta-lactamase KPC (Klebsiella pneumoniae) | BDBM50021959 (CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Service de Bactériologie-Virologie, Hôpital de Bicêtre Curated by ChEMBL | Assay Description Inhibition of carbapenem-resistant Klebsiella pneumoniae carbepenem-hydrolyzing beta-lactamase KPC-1 | Antimicrob Agents Chemother 54: 328-32 (2009) Article DOI: 10.1128/AAC.00961-09 BindingDB Entry DOI: 10.7270/Q2ZW1M3F | |||||||||||
More data for this Ligand-Target Pair |