Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50300028 (CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50300028 (CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323808 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323808 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323809 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323809 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein arginine N-methyltransferase 3 [N508S] (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein arginine N-methyltransferase 3 [N508S] (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity SET7/9 by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity SET7/9 by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase KMT5A (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity SET8/preSet7 by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase KMT5A (Homo sapiens (Human)) | BDBM50323813 (7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity SET8/preSet7 by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323805 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-7-(3-(met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323807 (6-Methoxy-7-(3-(methyl(propyl)amino)propoxy)-2-(4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323803 (7-(5-(Dimethylamino)pentyloxy)-6-methoxy-2-(4-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323807 (6-Methoxy-7-(3-(methyl(propyl)amino)propoxy)-2-(4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323806 (7-(3-(Diethylamino)propoxy)-6-methoxy-2-(4-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323814 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323806 (7-(3-(Diethylamino)propoxy)-6-methoxy-2-(4-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323803 (7-(5-(Dimethylamino)pentyloxy)-6-methoxy-2-(4-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323812 (7-(5-Aminopentyloxy)-6-methoxy-2-(4-methyl-1,4-dia...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323802 (7-(4-(Dimethylamino)butoxy)-6-methoxy-2-(4-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323814 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323801 (7-(2-(Dimethylamino)ethoxy)-6-methoxy-2-(4-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323805 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-7-(3-(met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323801 (7-(2-(Dimethylamino)ethoxy)-6-methoxy-2-(4-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323802 (7-(4-(Dimethylamino)butoxy)-6-methoxy-2-(4-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300030 (6,7-Dimaethoxy-2-(4-methylpiperazin-1-yl)-N-(1-met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323815 (CHEMBL1214068 | N1-(2-(6-Methoxy-2-(4-methyl-1,4-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.73E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300028 (CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300030 (6,7-Dimaethoxy-2-(4-methylpiperazin-1-yl)-N-(1-met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300029 (6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323812 (7-(5-Aminopentyloxy)-6-methoxy-2-(4-methyl-1,4-dia...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300028 (CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300029 (6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323815 (CHEMBL1214068 | N1-(2-(6-Methoxy-2-(4-methyl-1,4-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300031 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300031 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323810 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 8.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50323810 (6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human)) | BDBM50300034 (6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill Curated by ChEMBL | Assay Description Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay | J Med Chem 53: 5844-57 (2010) Article DOI: 10.1021/jm100478y BindingDB Entry DOI: 10.7270/Q2DZ08H1 | |||||||||||
More data for this Ligand-Target Pair |
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