Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50032200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325913 (2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14ClN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325914 (2-(3-(3-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1cccc(OCCCOc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14ClN3O3/c17-11-4-1-5-12(10-11)22-8-3-9-23-16-19-14-13(15(21)20-16)6-2-7-18-14/h1-2,4-7,10H,3,8-9H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325924 (2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Clc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14ClN3O2/c17-12-4-1-3-11(9-12)6-8-22-10-14-19-15-13(16(21)20-14)5-2-7-18-15/h1-5,7,9H,6,8,10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325908 (2-(3-phenoxypropoxy)pyrido[2,3-d]pyrimidin-4(3H)-o...) Show SMILES O=c1[nH]c(OCCCOc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C16H15N3O3/c20-15-13-8-4-9-17-14(13)18-16(19-15)22-11-5-10-21-12-6-2-1-3-7-12/h1-4,6-9H,5,10-11H2,(H,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325920 (2-((2-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14FN3O2/c17-13-6-2-1-4-11(13)7-9-22-10-14-19-15-12(16(21)20-14)5-3-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325921 (2-((3-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14FN3O2/c17-12-4-1-3-11(9-12)6-8-22-10-14-19-15-13(16(21)20-14)5-2-7-18-15/h1-5,7,9H,6,8,10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325915 (2-(3-(4-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1ccc(OCCCOc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14ClN3O3/c17-11-4-6-12(7-5-11)22-9-2-10-23-16-19-14-13(15(21)20-16)3-1-8-18-14/h1,3-8H,2,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325910 (2-(3-(2-fluorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Fc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14FN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325911 (2-(3-(3-fluorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Fc1cccc(OCCCOc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14FN3O3/c17-11-4-1-5-12(10-11)22-8-3-9-23-16-19-14-13(15(21)20-16)6-2-7-18-14/h1-2,4-7,10H,3,8-9H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325907 (2-(cinnamyloxy)pyrido[2,3-d]pyrimidin-4(3H)-one | ...) Show SMILES O=c1[nH]c(OC\C=C\c2ccccc2)nc2ncccc12 Show InChI InChI=1S/C16H13N3O2/c20-15-13-9-4-10-17-14(13)18-16(19-15)21-11-5-8-12-6-2-1-3-7-12/h1-10H,11H2,(H,17,18,19,20)/b8-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325899 (2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...) Show SMILES FC(F)(F)c1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C8H4F3N3O/c9-8(10,11)7-13-5-4(6(15)14-7)2-1-3-12-5/h1-3H,(H,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from rat GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325927 (2-(2-m-Tolyl-ethoxymethyl)-3H-pyrido[2,3-d]pyrimid...) Show SMILES Cc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C17H17N3O2/c1-12-4-2-5-13(10-12)7-9-22-11-15-19-16-14(17(21)20-15)6-3-8-18-16/h2-6,8,10H,7,9,11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325926 (2-(2-o-Tolyl-ethoxymethyl)-3H-pyrido[2,3-d]pyrimid...) Show SMILES Cc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C17H17N3O2/c1-12-5-2-3-6-13(12)8-10-22-11-15-19-16-14(17(21)20-15)7-4-9-18-16/h2-7,9H,8,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325916 (2-(3-(o-tolyloxy)propoxy)pyrido[2,3-d]pyrimidin-4(...) Show SMILES Cc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C17H17N3O3/c1-12-6-2-3-8-14(12)22-10-5-11-23-17-19-15-13(16(21)20-17)7-4-9-18-15/h2-4,6-9H,5,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325923 (2-((2-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Clc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14ClN3O2/c17-13-6-2-1-4-11(13)7-9-22-10-14-19-15-12(16(21)20-14)5-3-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325922 (2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325924 (2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Clc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14ClN3O2/c17-12-4-1-3-11(9-12)6-8-22-10-14-19-15-13(16(21)20-14)5-2-7-18-15/h1-5,7,9H,6,8,10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from rat GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325900 (2-((phenethyloxy)methyl)pyrido[2,3-d]pyrimidin-4(3...) Show SMILES O=c1[nH]c(COCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C16H15N3O2/c20-16-13-7-4-9-17-15(13)18-14(19-16)11-21-10-8-12-5-2-1-3-6-12/h1-7,9H,8,10-11H2,(H,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325896 (2-(4-phenylbutoxy)pyrido[2,3-d]pyrimidin-4(3H)-one...) Show SMILES O=c1[nH]c(OCCCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C17H17N3O2/c21-16-14-10-6-11-18-15(14)19-17(20-16)22-12-5-4-9-13-7-2-1-3-8-13/h1-3,6-8,10-11H,4-5,9,12H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325917 (2-(3-(m-tolyloxy)propoxy)pyrido[2,3-d]pyrimidin-4(...) Show SMILES Cc1cccc(OCCCOc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C17H17N3O3/c1-12-5-2-6-13(11-12)22-9-4-10-23-17-19-15-14(16(21)20-17)7-3-8-18-15/h2-3,5-8,11H,4,9-10H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325909 (CHEMBL1223958 | N-((3,4-dihydro-4-oxopyrido[2,3-d]...) Show SMILES O=C(CCc1ccccc1)NCc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N4O2/c22-15(9-8-12-5-2-1-3-6-12)19-11-14-20-16-13(17(23)21-14)7-4-10-18-16/h1-7,10H,8-9,11H2,(H,19,22)(H,18,20,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325912 (2-(3-(4-fluorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Fc1ccc(OCCCOc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14FN3O3/c17-11-4-6-12(7-5-11)22-9-2-10-23-16-19-14-13(15(21)20-16)3-1-8-18-14/h1,3-8H,2,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325925 (2-((4-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Clc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14ClN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325899 (2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...) Show SMILES FC(F)(F)c1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C8H4F3N3O/c9-8(10,11)7-13-5-4(6(15)14-7)2-1-3-12-5/h1-3H,(H,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325913 (2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14ClN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from rat GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325930 (2-((3-methoxyphenethyloxy)methyl)pyrido[2,3-d]pyri...) Show SMILES COc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C17H17N3O3/c1-22-13-5-2-4-12(10-13)7-9-23-11-15-19-16-14(17(21)20-15)6-3-8-18-16/h2-6,8,10H,7,9,11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325929 (2-((2-methoxyphenethyloxy)methyl)pyrido[2,3-d]pyri...) Show SMILES COc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C17H17N3O3/c1-22-14-7-3-2-5-12(14)8-10-23-11-15-19-16-13(17(21)20-15)6-4-9-18-16/h2-7,9H,8,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325922 (2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from rat GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325928 (2-(2-p-Tolyl-ethoxymethyl)-3H-pyrido[2,3-d]pyrimid...) Show SMILES Cc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H17N3O2/c1-12-4-6-13(7-5-12)8-10-22-11-15-19-16-14(17(21)20-15)3-2-9-18-16/h2-7,9H,8,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325931 (2-((4-methoxyphenethyloxy)methyl)pyrido[2,3-d]pyri...) Show SMILES COc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H17N3O3/c1-22-13-6-4-12(5-7-13)8-10-23-11-15-19-16-14(17(21)20-15)3-2-9-18-16/h2-7,9H,8,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325904 (2-(4-phenylbutyl)pyrido[2,3-d]pyrimidin-4(3H)-one ...) Show SMILES O=c1[nH]c(CCCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C17H17N3O/c21-17-14-10-6-12-18-16(14)19-15(20-17)11-5-4-9-13-7-2-1-3-8-13/h1-3,6-8,10,12H,4-5,9,11H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325918 (2-(3-(p-tolyloxy)propoxy)pyrido[2,3-d]pyrimidin-4(...) Show SMILES Cc1ccc(OCCCOc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H17N3O3/c1-12-5-7-13(8-6-12)22-10-3-11-23-17-19-15-14(16(21)20-17)4-2-9-18-15/h2,4-9H,3,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325897 (2-(5-phenylpentyl)pyrido[2,3-d]pyrimidin-4(3H)-one...) Show SMILES O=c1[nH]c(CCCCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C18H19N3O/c22-18-15-11-7-13-19-17(15)20-16(21-18)12-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,11,13H,2,5-6,10,12H2,(H,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325919 (2-(3-(4-methoxyphenoxy)propoxy)pyrido[2,3-d]pyrimi...) Show SMILES COc1ccc(OCCCOc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H17N3O4/c1-22-12-5-7-13(8-6-12)23-10-3-11-24-17-19-15-14(16(21)20-17)4-2-9-18-15/h2,4-9H,3,10-11H2,1H3,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325901 (2-(6-phenylhexyl)pyrido[2,3-d]pyrimidin-4(3H)-one ...) Show SMILES O=c1[nH]c(CCCCCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C19H21N3O/c23-19-16-12-8-14-20-18(16)21-17(22-19)13-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-12,14H,1-2,4,7,9,13H2,(H,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50325913 (2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14ClN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109B				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325903 (2-(7-phenylheptyl)pyrido[2,3-d]pyrimidin-4(3H)-one...) Show SMILES O=c1[nH]c(CCCCCCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C20H23N3O/c24-20-17-13-9-15-21-19(17)22-18(23-20)14-8-3-1-2-5-10-16-11-6-4-7-12-16/h4,6-7,9,11-13,15H,1-3,5,8,10,14H2,(H,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325906 (2-(3-phenoxypropyl)pyrido[2,3-d]pyrimidin-4(3H)-on...) Show SMILES O=c1[nH]c(CCCOc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C16H15N3O2/c20-16-13-8-4-10-17-15(13)18-14(19-16)9-5-11-21-12-6-2-1-3-7-12/h1-4,6-8,10H,5,9,11H2,(H,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325905 (2-benzylpyrido[2,3-d]pyrimidin-4(3H)-one | CHEMBL1...) Show SMILES O=c1[nH]c(Cc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C14H11N3O/c18-14-11-7-4-8-15-13(11)16-12(17-14)9-10-5-2-1-3-6-10/h1-8H,9H2,(H,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50325922 (2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109B				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325898 (2-phenethylpyrido[2,3-d]pyrimidin-4(3H)-one | CHEM...) Show SMILES O=c1[nH]c(CCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C15H13N3O/c19-15-12-7-4-10-16-14(12)17-13(18-15)9-8-11-5-2-1-3-6-11/h1-7,10H,8-9H2,(H,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325902 (2-(3-phenylpropyl)pyrido[2,3-d]pyrimidin-4(3H)-one...) Show SMILES O=c1[nH]c(CCCc2ccccc2)nc2ncccc12 Show InChI InChI=1S/C16H15N3O/c20-16-13-9-5-11-17-15(13)18-14(19-16)10-4-8-12-6-2-1-3-7-12/h1-3,5-7,9,11H,4,8,10H2,(H,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50325899 (2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...) Show SMILES FC(F)(F)c1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C8H4F3N3O/c9-8(10,11)7-13-5-4(6(15)14-7)2-1-3-12-5/h1-3H,(H,12,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109B				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325924 (2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Clc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14ClN3O2/c17-12-4-1-3-11(9-12)6-8-22-10-14-19-15-13(16(21)20-14)5-2-7-18-15/h1-5,7,9H,6,8,10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at rat GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325922 (2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at rat GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325924 (2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Clc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C16H14ClN3O2/c17-12-4-1-3-11(9-12)6-8-22-10-14-19-15-13(16(21)20-14)5-2-7-18-15/h1-5,7,9H,6,8,10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325922 (2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...) Show SMILES Fc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325913 (2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14ClN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325899 (2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...) Show SMILES FC(F)(F)c1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C8H4F3N3O/c9-8(10,11)7-13-5-4(6(15)14-7)2-1-3-12-5/h1-3H,(H,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50325913 (2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...) Show SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14ClN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at rat GPR109A receptor assessed as GTPgammaS binding				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 51 total )  |  Next  |  Last  >>

Jump to: