Found 7 hits Enz. Inhib. hit(s) with all data for entry = 50032249 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 497 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to adrenergic alpha1D receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 758 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to adrenergic alpha1B receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 885 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to adrenergic alpha1A receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to kappa opioid receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to 5HT1E receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-2
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to nicotinic alpha3beta2 receptor receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50326197
(1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...)Show InChI InChI=1S/C7H9N5O2/c1-11-4(8)3-5(10-7(11)14)12(2)6(13)9-3/h8H2,1-2H3,(H,9,13) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
J Med Chem 53: 6089-99 (2010)
Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7 |
More data for this Ligand-Target Pair | |