Compile Data Set for Download or QSAR

Found 33 hits Enz. Inhib. hit(s) with all data for entry = 50032342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327416 (1-(2-(2-(2-(dimethylamino)ethylamino)-6-(2-(isopro...) Show SMILES CNC(=O)NCc1ccccc1-c1cc(nc(NCCN(C)C)n1)-c1cnc(NC(C)C)s1 Show InChI InChI=1S/C23H32N8OS/c1-15(2)28-23-27-14-20(33-23)19-12-18(29-21(30-19)25-10-11-31(4)5)17-9-7-6-8-16(17)13-26-22(32)24-3/h6-9,12,14-15H,10-11,13H2,1-5H3,(H,27,28)(H2,24,26,32)(H,25,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50327391 (CHEMBL1258976 | N1-(4-(2-chlorophenyl)-6-(2-(isopr...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCCN(C)C)n1)-c1ccccc1Cl Show InChI InChI=1S/C20H25ClN6S/c1-13(2)24-20-23-12-18(28-20)17-11-16(14-7-5-6-8-15(14)21)25-19(26-17)22-9-10-27(3)4/h5-8,11-13H,9-10H2,1-4H3,(H,23,24)(H,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.05	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of LIMK2				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327390 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl Show InChI InChI=1S/C21H18ClN5S/c1-13(2)25-21-24-12-19(28-21)18-11-17(14-7-3-4-8-15(14)22)26-20(27-18)16-9-5-6-10-23-16/h3-13H,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50327391 (CHEMBL1258976 | N1-(4-(2-chlorophenyl)-6-(2-(isopr...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCCN(C)C)n1)-c1ccccc1Cl Show InChI InChI=1S/C20H25ClN6S/c1-13(2)24-20-23-12-18(28-20)17-11-16(14-7-5-6-8-15(14)21)25-19(26-17)22-9-10-27(3)4/h5-8,11-13H,9-10H2,1-4H3,(H,23,24)(H,22,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.01	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of LIMK1				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327391 (CHEMBL1258976 | N1-(4-(2-chlorophenyl)-6-(2-(isopr...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCCN(C)C)n1)-c1ccccc1Cl Show InChI InChI=1S/C20H25ClN6S/c1-13(2)24-20-23-12-18(28-20)17-11-16(14-7-5-6-8-15(14)21)25-19(26-17)22-9-10-27(3)4/h5-8,11-13H,9-10H2,1-4H3,(H,23,24)(H,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327410 ((R)-N-sec-butyl-5-(6-(2-chlorophenyl)-2-(pyridin-2...) Show SMILES CC[C@@H](C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl |r| Show InChI InChI=1S/C22H20ClN5S/c1-3-14(2)26-22-25-13-20(29-22)19-12-18(15-8-4-5-9-16(15)23)27-21(28-19)17-10-6-7-11-24-17/h4-14H,3H2,1-2H3,(H,25,26)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327415 (3-(4-(2-chlorophenyl)-6-(2-(isopropylamino)thiazol...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCC(O)CO)n1)-c1ccccc1Cl Show InChI InChI=1S/C19H22ClN5O2S/c1-11(2)23-19-22-9-17(28-19)16-7-15(13-5-3-4-6-14(13)20)24-18(25-16)21-8-12(27)10-26/h3-7,9,11-12,26-27H,8,10H2,1-2H3,(H,22,23)(H,21,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327417 (1-(2-(2-(2-(dimethylamino)ethylamino)-6-(2-(isopro...) Show SMILES CCNC(=O)NCc1ccccc1-c1cc(nc(NCCN(C)C)n1)-c1cnc(NC(C)C)s1 Show InChI InChI=1S/C24H34N8OS/c1-6-25-23(33)27-14-17-9-7-8-10-18(17)19-13-20(21-15-28-24(34-21)29-16(2)3)31-22(30-19)26-11-12-32(4)5/h7-10,13,15-16H,6,11-12,14H2,1-5H3,(H,28,29)(H2,25,27,33)(H,26,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327414 (2-(4-(2-chlorophenyl)-6-(2-(isopropylamino)thiazol...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCCO)n1)-c1ccccc1Cl Show InChI InChI=1S/C18H20ClN5OS/c1-11(2)22-18-21-10-16(26-18)15-9-14(12-5-3-4-6-13(12)19)23-17(24-15)20-7-8-25/h3-6,9-11,25H,7-8H2,1-2H3,(H,21,22)(H,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327409 ((S)-N-sec-butyl-5-(6-(2-chlorophenyl)-2-(pyridin-2...) Show SMILES CC[C@H](C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl |r| Show InChI InChI=1S/C22H20ClN5S/c1-3-14(2)26-22-25-13-20(29-22)19-12-18(15-8-4-5-9-16(15)23)27-21(28-19)17-10-6-7-11-24-17/h4-14H,3H2,1-2H3,(H,25,26)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327408 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES Clc1ccccc1-c1cc(nc(n1)-c1ccccn1)-c1cnc(NC2CCC2)s1 Show InChI InChI=1S/C22H18ClN5S/c23-16-9-2-1-8-15(16)18-12-19(28-21(27-18)17-10-3-4-11-24-17)20-13-25-22(29-20)26-14-6-5-7-14/h1-4,8-14H,5-7H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327418 (1-cyclopropyl-3-(2-(2-(2-(dimethylamino)ethylamino...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCCN(C)C)n1)-c1ccccc1CNC(=O)NC1CC1 Show InChI InChI=1S/C25H34N8OS/c1-16(2)29-25-28-15-22(35-25)21-13-20(31-23(32-21)26-11-12-33(3)4)19-8-6-5-7-17(19)14-27-24(34)30-18-9-10-18/h5-8,13,15-16,18H,9-12,14H2,1-4H3,(H,28,29)(H,26,31,32)(H2,27,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327412 (5-(2-amino-6-(2-chlorophenyl)pyrimidin-4-yl)-N-iso...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(N)n1)-c1ccccc1Cl Show InChI InChI=1S/C16H16ClN5S/c1-9(2)20-16-19-8-14(23-16)13-7-12(21-15(18)22-13)10-5-3-4-6-11(10)17/h3-9H,1-2H3,(H,19,20)(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327406 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl Show InChI InChI=1S/C20H16ClN5S/c1-2-22-20-24-12-18(27-20)17-11-16(13-7-3-4-8-14(13)21)25-19(26-17)15-9-5-6-10-23-15/h3-12H,2H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327407 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES Clc1ccccc1-c1cc(nc(n1)-c1ccccn1)-c1cnc(NC2CC2)s1 Show InChI InChI=1S/C21H16ClN5S/c22-15-6-2-1-5-14(15)17-11-18(19-12-24-21(28-19)25-13-8-9-13)27-20(26-17)16-7-3-4-10-23-16/h1-7,10-13H,8-9H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327401 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl Show InChI InChI=1S/C21H18ClN5S/c1-2-10-24-21-25-13-19(28-21)18-12-17(14-7-3-4-8-15(14)22)26-20(27-18)16-9-5-6-11-23-16/h3-9,11-13H,2,10H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327403 (5-(6-(2-chloro-4-fluorophenyl)-2-(pyridin-2-yl)pyr...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccc(F)cc1Cl Show InChI InChI=1S/C21H17ClFN5S/c1-2-8-25-21-26-12-19(29-21)18-11-17(14-7-6-13(23)10-15(14)22)27-20(28-18)16-5-3-4-9-24-16/h3-7,9-12H,2,8H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327411 (5-(6-(2-chlorophenyl)pyrimidin-4-yl)-N-isopropylth...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(ncn1)-c1ccccc1Cl Show InChI InChI=1S/C16H15ClN4S/c1-10(2)21-16-18-8-15(22-16)14-7-13(19-9-20-14)11-5-3-4-6-12(11)17/h3-10H,1-2H3,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327399 (5-(6-(4-fluorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H18FN5S/c1-2-10-24-21-25-13-19(28-21)18-12-17(14-6-8-15(22)9-7-14)26-20(27-18)16-5-3-4-11-23-16/h3-9,11-13H,2,10H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327400 (5-(6-(2-fluorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1F Show InChI InChI=1S/C21H18FN5S/c1-2-10-24-21-25-13-19(28-21)18-12-17(14-7-3-4-8-15(14)22)26-20(27-18)16-9-5-6-11-23-16/h3-9,11-13H,2,10H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327405 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl Show InChI InChI=1S/C18H12ClN5S/c19-12-6-2-1-5-11(12)14-9-15(16-10-22-18(20)25-16)24-17(23-14)13-7-3-4-8-21-13/h1-10H,(H2,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327392 (5-(2-(2-chlorophenyl)pyrimidin-4-yl)-N-isopropylth...) Show SMILES CC(C)Nc1ncc(s1)-c1ccnc(n1)-c1ccccc1Cl Show InChI InChI=1S/C16H15ClN4S/c1-10(2)20-16-19-9-14(22-16)13-7-8-18-15(21-13)11-5-3-4-6-12(11)17/h3-10H,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327393 (5-(2-amino-6-(2-fluorophenyl)pyrimidin-4-yl)-N-pro...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(N)n1)-c1ccccc1F Show InChI InChI=1S/C16H16FN5S/c1-2-7-19-16-20-9-14(23-16)13-8-12(21-15(18)22-13)10-5-3-4-6-11(10)17/h3-6,8-9H,2,7H2,1H3,(H,19,20)(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50327390 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl Show InChI InChI=1S/C21H18ClN5S/c1-13(2)25-21-24-12-19(28-21)18-11-17(14-7-3-4-8-15(14)22)26-20(27-18)16-9-5-6-10-23-16/h3-13H,1-2H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of LIMK1				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327398 (CHEMBL1258065 | N-propyl-5-(2-(pyridin-2-yl)pyrimi...) Show SMILES CCCNc1ncc(s1)-c1ccnc(n1)-c1ccccn1 Show InChI InChI=1S/C15H15N5S/c1-2-7-18-15-19-10-13(21-15)11-6-9-17-14(20-11)12-5-3-4-8-16-12/h3-6,8-10H,2,7H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50327390 (5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl Show InChI InChI=1S/C21H18ClN5S/c1-13(2)25-21-24-12-19(28-21)18-11-17(14-7-3-4-8-15(14)22)26-20(27-18)16-9-5-6-10-23-16/h3-13H,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	362	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of LIMK2				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327394 (5-(6-(2-fluorophenyl)-2-methylpyrimidin-4-yl)-N-pr...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(C)n1)-c1ccccc1F Show InChI InChI=1S/C17H17FN4S/c1-3-8-19-17-20-10-16(23-17)15-9-14(21-11(2)22-15)12-6-4-5-7-13(12)18/h4-7,9-10H,3,8H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327413 (5-(6-(2-chlorophenyl)-2-(dimethylamino)pyrimidin-4...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(n1)N(C)C)-c1ccccc1Cl Show InChI InChI=1S/C18H20ClN5S/c1-11(2)21-18-20-10-16(25-18)15-9-14(22-17(23-15)24(3)4)12-7-5-6-8-13(12)19/h5-11H,1-4H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	573	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327402 (5-(6-(2-ethoxyphenyl)-2-(pyridin-2-yl)pyrimidin-4-...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1OCC Show InChI InChI=1S/C23H23N5OS/c1-3-12-25-23-26-15-21(30-23)19-14-18(16-9-5-6-11-20(16)29-4-2)27-22(28-19)17-10-7-8-13-24-17/h5-11,13-15H,3-4,12H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	859	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327397 (5-(2-cyclopropylpyrimidin-4-yl)-N-propylthiazol-2-...) Show SMILES CCCNc1ncc(s1)-c1ccnc(n1)C1CC1 Show InChI InChI=1S/C13H16N4S/c1-2-6-15-13-16-8-11(18-13)10-5-7-14-12(17-10)9-3-4-9/h5,7-9H,2-4,6H2,1H3,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327395 (5-(2-cyclopropyl-6-(2-fluorophenyl)pyrimidin-4-yl)...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)C1CC1)-c1ccccc1F Show InChI InChI=1S/C19H19FN4S/c1-2-9-21-19-22-11-17(25-19)16-10-15(13-5-3-4-6-14(13)20)23-18(24-16)12-7-8-12/h3-6,10-12H,2,7-9H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327404 (5-(6-(2-chloro-4-ethoxyphenyl)-2-(pyridin-2-yl)pyr...) Show SMILES CCCNc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccc(OCC)cc1Cl Show InChI InChI=1S/C23H22ClN5OS/c1-3-10-26-23-27-14-21(31-23)20-13-19(16-9-8-15(30-4-2)12-17(16)24)28-22(29-20)18-7-5-6-11-25-18/h5-9,11-14H,3-4,10H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327396 (5-(2-(2-fluorophenyl)pyrimidin-4-yl)-N-propylthiaz...) Show SMILES CCCNc1ncc(s1)-c1ccnc(n1)-c1ccccc1F Show InChI InChI=1S/C16H15FN4S/c1-2-8-19-16-20-10-14(22-16)13-7-9-18-15(21-13)11-5-3-4-6-12(11)17/h3-7,9-10H,2,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair