Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50032422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50217569 (4-(3-(4-(piperidin-1-yl)but-1-ynyl)benzyl)morpholi...) Show SMILES C(CN1CCCCC1)C#Cc1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C20H28N2O/c1-3-10-21(11-4-1)12-5-2-7-19-8-6-9-20(17-19)18-22-13-15-23-16-14-22/h6,8-9,17H,1,3-5,10-16,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328940 ((4-isopropyl-1,4-diazepan-1-yl)(1-methyl-3-(morpho...) Show SMILES CC(C)N1CCCN(CC1)C(=O)c1ccc2c(CN3CCOCC3)cn(C)c2c1 Show InChI InChI=1S/C23H34N4O2/c1-18(2)26-7-4-8-27(10-9-26)23(28)19-5-6-21-20(16-24(3)22(21)15-19)17-25-11-13-29-14-12-25/h5-6,15-16,18H,4,7-14,17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328939 ((4-cyclobutylpiperazin-1-yl)(3-(morpholinomethyl)-...) Show SMILES O=C(N1CCN(CC1)C1CCC1)c1ccc2c(CN3CCOCC3)c[nH]c2c1 Show InChI InChI=1S/C22H30N4O2/c27-22(26-8-6-25(7-9-26)19-2-1-3-19)17-4-5-20-18(15-23-21(20)14-17)16-24-10-12-28-13-11-24/h4-5,14-15,19,23H,1-3,6-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328942 ((4-cyclobutylpiperazin-1-yl)(3-(piperidin-1-ylmeth...) Show SMILES O=C(N1CCN(CC1)C1CCC1)c1cccc2c(CN3CCCCC3)c[nH]c12 Show InChI InChI=1S/C23H32N4O/c28-23(27-14-12-26(13-15-27)19-6-4-7-19)21-9-5-8-20-18(16-24-22(20)21)17-25-10-2-1-3-11-25/h5,8-9,16,19,24H,1-4,6-7,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328935 ((4-isopropylpiperazin-1-yl)(1-(methylsulfonyl)-3-(...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2c(CN3CCCCC3)cn(c2c1)S(C)(=O)=O Show InChI InChI=1S/C23H34N4O3S/c1-18(2)25-11-13-26(14-12-25)23(28)19-7-8-21-20(16-24-9-5-4-6-10-24)17-27(22(21)15-19)31(3,29)30/h7-8,15,17-18H,4-6,9-14,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328938 ((4-cyclopropylpiperazin-1-yl)(3-(morpholinomethyl)...) Show SMILES O=C(N1CCN(CC1)C1CC1)c1ccc2c(CN3CCOCC3)c[nH]c2c1 Show InChI InChI=1S/C21H28N4O2/c26-21(25-7-5-24(6-8-25)18-2-3-18)16-1-4-19-17(14-22-20(19)13-16)15-23-9-11-27-12-10-23/h1,4,13-14,18,22H,2-3,5-12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50217581 (4-(4-(1-isopropylpiperidin-4-yloxy)benzyl)morpholi...) Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C19H30N2O2/c1-16(2)21-9-7-19(8-10-21)23-18-5-3-17(4-6-18)15-20-11-13-22-14-12-20/h3-6,16,19H,7-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328932 ((4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2c(CN3CCOCC3)c[nH]c2c1 Show InChI InChI=1S/C21H30N4O2/c1-16(2)24-5-7-25(8-6-24)21(26)17-3-4-19-18(14-22-20(19)13-17)15-23-9-11-27-12-10-23/h3-4,13-14,16,22H,5-12,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328931 ((4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethy...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2c(CN3CCCCC3)c[nH]c2c1 Show InChI InChI=1S/C22H32N4O/c1-17(2)25-10-12-26(13-11-25)22(27)18-6-7-20-19(15-23-21(20)14-18)16-24-8-4-3-5-9-24/h6-7,14-15,17,23H,3-5,8-13,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328943 ((4-cyclobutylpiperazin-1-yl)(3-(morpholinomethyl)-...) Show SMILES O=C(N1CCN(CC1)C1CCC1)c1cccc2c(CN3CCOCC3)c[nH]c12 Show InChI InChI=1S/C22H30N4O2/c27-22(26-9-7-25(8-10-26)18-3-1-4-18)20-6-2-5-19-17(15-23-21(19)20)16-24-11-13-28-14-12-24/h2,5-6,15,18,23H,1,3-4,7-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328934 ((4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1cccc2c(CN3CCOCC3)c[nH]c12 Show InChI InChI=1S/C21H30N4O2/c1-16(2)24-6-8-25(9-7-24)21(26)19-5-3-4-18-17(14-22-20(18)19)15-23-10-12-27-13-11-23/h3-5,14,16,22H,6-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328941 ((4-isopropylpiperazin-1-yl)(1-methyl-3-(morpholino...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2c(CN3CCOCC3)cn(C)c2c1 Show InChI InChI=1S/C22H32N4O2/c1-17(2)25-6-8-26(9-7-25)22(27)18-4-5-20-19(15-23(3)21(20)14-18)16-24-10-12-28-13-11-24/h4-5,14-15,17H,6-13,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328947 ((4-cyclobutylpiperazin-1-yl)(3-(piperidin-1-ylmeth...) Show SMILES O=C(N1CCN(CC1)C1CCC1)c1ccc2scc(CN3CCCCC3)c2c1 Show InChI InChI=1S/C23H31N3OS/c27-23(26-13-11-25(12-14-26)20-5-4-6-20)18-7-8-22-21(15-18)19(17-28-22)16-24-9-2-1-3-10-24/h7-8,15,17,20H,1-6,9-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328927 ((4-cyclopropylpiperazin-1-yl)(4-(3,4-dichloropheno...) Show SMILES CNCc1cc(ccc1Oc1ccc(Cl)c(Cl)c1)C(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C22H25Cl2N3O2/c1-25-14-16-12-15(22(28)27-10-8-26(9-11-27)17-3-4-17)2-7-21(16)29-18-5-6-19(23)20(24)13-18/h2,5-7,12-13,17,25H,3-4,8-11,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328933 ((4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethy...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1cccc2c(CN3CCCCC3)c[nH]c12 Show InChI InChI=1S/C22H32N4O/c1-17(2)25-11-13-26(14-12-25)22(27)20-8-6-7-19-18(15-23-21(19)20)16-24-9-4-3-5-10-24/h6-8,15,17,23H,3-5,9-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328937 ((3-((4-cyclobutylpiperazin-1-yl)methyl)-1H-indol-6...) Show SMILES O=C(N1CCOCC1)c1ccc2c(CN3CCN(CC3)C3CCC3)c[nH]c2c1 Show InChI InChI=1S/C22H30N4O2/c27-22(26-10-12-28-13-11-26)17-4-5-20-18(15-23-21(20)14-17)16-24-6-8-25(9-7-24)19-2-1-3-19/h4-5,14-15,19,23H,1-3,6-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328946 ((4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethy...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2scc(CN3CCCCC3)c2c1 Show InChI InChI=1S/C22H31N3OS/c1-17(2)24-10-12-25(13-11-24)22(26)18-6-7-21-20(14-18)19(16-27-21)15-23-8-4-3-5-9-23/h6-7,14,16-17H,3-5,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328929 ((4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethy...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2[nH]cc(CN3CCCCC3)c2c1 Show InChI InChI=1S/C22H32N4O/c1-17(2)25-10-12-26(13-11-25)22(27)18-6-7-21-20(14-18)19(15-23-21)16-24-8-4-3-5-9-24/h6-7,14-15,17,23H,3-5,8-13,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328936 ((3-((4-isopropylpiperazin-1-yl)methyl)-1H-indol-6-...) Show SMILES CC(C)N1CCN(Cc2c[nH]c3cc(ccc23)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C22H32N4O/c1-17(2)25-12-10-24(11-13-25)16-19-15-23-21-14-18(6-7-20(19)21)22(27)26-8-4-3-5-9-26/h6-7,14-15,17,23H,3-5,8-13,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328930 ((4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2[nH]cc(CN3CCOCC3)c2c1 Show InChI InChI=1S/C21H30N4O2/c1-16(2)24-5-7-25(8-6-24)21(26)17-3-4-20-19(13-17)18(14-22-20)15-23-9-11-27-12-10-23/h3-4,13-14,16,22H,5-12,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328945 ((3-((4-cyclobutylpiperazin-1-yl)methyl)-1H-indol-7...) Show SMILES O=C(N1CCCCC1)c1cccc2c(CN3CCN(CC3)C3CCC3)c[nH]c12 Show InChI InChI=1S/C23H32N4O/c28-23(27-10-2-1-3-11-27)21-9-5-8-20-18(16-24-22(20)21)17-25-12-14-26(15-13-25)19-6-4-7-19/h5,8-9,16,19,24H,1-4,6-7,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328949 ((4-cyclobutylpiperazin-1-yl)(3-(piperidine-1-carbo...) Show SMILES O=C(N1CCCCC1)c1csc2ccc(cc12)C(=O)N1CCN(CC1)C1CCC1 Show InChI InChI=1S/C23H29N3O2S/c27-22(26-13-11-24(12-14-26)18-5-4-6-18)17-7-8-21-19(15-17)20(16-29-21)23(28)25-9-2-1-3-10-25/h7-8,15-16,18H,1-6,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328944 ((3-(morpholinomethyl)-1H-indol-7-yl)(piperazin-1-y...) Show SMILES O=C(N1CCNCC1)c1cccc2c(CN3CCOCC3)c[nH]c12 Show InChI InChI=1S/C18H24N4O2/c23-18(22-6-4-19-5-7-22)16-3-1-2-15-14(12-20-17(15)16)13-21-8-10-24-11-9-21/h1-3,12,19-20H,4-11,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328948 ((4-isopropylpiperazin-1-yl)(3-(piperidine-1-carbon...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2scc(C(=O)N3CCCCC3)c2c1 Show InChI InChI=1S/C22H29N3O2S/c1-16(2)23-10-12-25(13-11-23)21(26)17-6-7-20-18(14-17)19(15-28-20)22(27)24-8-4-3-5-9-24/h6-7,14-16H,3-5,8-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328928 ((4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1cccc2[nH]cc(CN3CCOCC3)c12 Show InChI InChI=1S/C21H30N4O2/c1-16(2)24-6-8-25(9-7-24)21(26)18-4-3-5-19-20(18)17(14-22-19)15-23-10-12-27-13-11-23/h3-5,14,16,22H,6-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair