Found 22 hits Enz. Inhib. hit(s) with all data for entry = 50032987 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prothrombin
(Homo sapiens (Human)) | BDBM50337483
(CHEMBL1682777 | N1-(5-chloro-2-(1H-tetrazol-1-yl)b...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C25H31ClN6O2/c1-16(2)13-31(14-17(3)4)25(34)20-9-18(5)8-19(10-20)24(33)27-12-21-11-22(26)6-7-23(21)32-15-28-29-30-32/h6-11,15-17H,12-14H2,1-5H3,(H,27,33) | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337479
(CHEMBL1682781 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES CC(C)c1ccncc1-c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C24H23ClN6O/c1-15(2)21-6-7-26-13-22(21)17-8-16(3)9-18(10-17)24(32)27-12-19-11-20(25)4-5-23(19)31-14-28-29-30-31/h4-11,13-15H,12H2,1-3H3,(H,27,32) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337485
(CHEMBL1682775 | N1-(2-(aminomethyl)-5-chlorobenzyl...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1CN Show InChI InChI=1S/C25H34ClN3O2/c1-16(2)14-29(15-17(3)4)25(31)21-9-18(5)8-20(10-21)24(30)28-13-22-11-23(26)7-6-19(22)12-27/h6-11,16-17H,12-15,27H2,1-5H3,(H,28,30) | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 0.680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337487
(CHEMBL1682773 | methyl 2-(4-chloro-2-(2-(3-(diisob...)Show SMILES COC(=O)COc1ccc(Cl)cc1CCOc1cc(C)cc(c1)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C27H36ClNO5/c1-18(2)15-29(16-19(3)4)27(31)22-11-20(5)12-24(14-22)33-10-9-21-13-23(28)7-8-25(21)34-17-26(30)32-6/h7-8,11-14,18-19H,9-10,15-17H2,1-6H3 | PDB
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UniChem
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| Article
PubMed
| 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337478
(3-(3-(5-chloro-2-(1H-tetrazol-1-yl)benzylcarbamoyl...)Show SMILES CC(C)c1cc[n+]([O-])cc1-c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C24H23ClN6O2/c1-15(2)21-6-7-30(33)13-22(21)17-8-16(3)9-18(10-17)24(32)26-12-19-11-20(25)4-5-23(19)31-14-27-28-29-31/h4-11,13-15H,12H2,1-3H3,(H,26,32) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 0.770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337488
(3-(5-chloro-2-(1H-1,2,4-triazol-1-yl)phenethoxy)-N...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(OCCc2cc(Cl)ccc2-n2cncn2)c1 Show InChI InChI=1S/C26H33ClN4O2/c1-18(2)14-30(15-19(3)4)26(32)22-10-20(5)11-24(13-22)33-9-8-21-12-23(27)6-7-25(21)31-17-28-16-29-31/h6-7,10-13,16-19H,8-9,14-15H2,1-5H3 | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337474
(CHEMBL1682786 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES Cc1cc(cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1)N(C1CCCCC1)S(C)(=O)=O Show InChI InChI=1S/C23H27ClN6O3S/c1-16-10-17(13-21(11-16)30(34(2,32)33)20-6-4-3-5-7-20)23(31)25-14-18-12-19(24)8-9-22(18)29-15-26-27-28-29/h8-13,15,20H,3-7,14H2,1-2H3,(H,25,31) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337472
(CHEMBL1682788 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES Cc1cc(cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1)N(C1CCCC1)S(C)(=O)=O Show InChI InChI=1S/C22H25ClN6O3S/c1-15-9-16(12-20(10-15)29(33(2,31)32)19-5-3-4-6-19)22(30)24-13-17-11-18(23)7-8-21(17)28-14-25-26-27-28/h7-12,14,19H,3-6,13H2,1-2H3,(H,24,30) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| 1.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337473
(3-((2-aminoethyl)(cyclohexyl)amino)-N-(5-chloro-2-...)Show SMILES Cc1cc(cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1)N(CCN)C1CCCCC1 Show InChI InChI=1S/C24H30ClN7O/c1-17-11-18(14-22(12-17)31(10-9-26)21-5-3-2-4-6-21)24(33)27-15-19-13-20(25)7-8-23(19)32-16-28-29-30-32/h7-8,11-14,16,21H,2-6,9-10,15,26H2,1H3,(H,27,33) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337486
(3-(5-chloro-2-(2-oxo-2-(piperidin-3-ylamino)ethoxy...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(OCCc2cc(Cl)ccc2OCC(=O)NC2CCCNC2)c1 Show InChI InChI=1S/C31H44ClN3O4/c1-21(2)18-35(19-22(3)4)31(37)25-13-23(5)14-28(16-25)38-12-10-24-15-26(32)8-9-29(24)39-20-30(36)34-27-7-6-11-33-17-27/h8-9,13-16,21-22,27,33H,6-7,10-12,17-20H2,1-5H3,(H,34,36) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337489
(3-(2-(1H-tetrazol-1-yl)phenethoxy)-N,N-diisobutyl-...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(OCCc2ccccc2-n2cnnn2)c1 Show InChI InChI=1S/C25H33N5O2/c1-18(2)15-29(16-19(3)4)25(31)22-12-20(5)13-23(14-22)32-11-10-21-8-6-7-9-24(21)30-17-26-27-28-30/h6-9,12-14,17-19H,10-11,15-16H2,1-5H3 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337477
(CHEMBL1682783 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES CC(C)CC1CCNCC1c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C25H31ClN6O/c1-16(2)8-18-6-7-27-14-23(18)19-9-17(3)10-20(11-19)25(33)28-13-21-12-22(26)4-5-24(21)32-15-29-30-31-32/h4-5,9-12,15-16,18,23,27H,6-8,13-14H2,1-3H3,(H,28,33) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337491
(3-(2-(aminomethyl)phenethoxy)-N,N-diisobutyl-5-met...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(OCCc2ccccc2CN)c1 Show InChI InChI=1S/C25H36N2O2/c1-18(2)16-27(17-19(3)4)25(28)23-12-20(5)13-24(14-23)29-11-10-21-8-6-7-9-22(21)15-26/h6-9,12-14,18-19H,10-11,15-17,26H2,1-5H3 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337493
(CHEMBL1682767 | N,N-diisobutyl-3-methyl-5-(2-(5-me...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(OCCc2[nH]cnc2C)c1 Show InChI InChI=1S/C22H33N3O2/c1-15(2)12-25(13-16(3)4)22(26)19-9-17(5)10-20(11-19)27-8-7-21-18(6)23-14-24-21/h9-11,14-16H,7-8,12-13H2,1-6H3,(H,23,24) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337475
(CHEMBL1682785 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES CC(=O)N(C1CCCCC1)c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C24H27ClN6O2/c1-16-10-18(13-22(11-16)31(17(2)32)21-6-4-3-5-7-21)24(33)26-14-19-12-20(25)8-9-23(19)30-15-27-28-29-30/h8-13,15,21H,3-7,14H2,1-2H3,(H,26,33) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337484
(CHEMBL1682776 | N1-(5-chloro-2-(1H-1,2,4-triazol-1...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cncn1 Show InChI InChI=1S/C26H32ClN5O2/c1-17(2)13-31(14-18(3)4)26(34)21-9-19(5)8-20(10-21)25(33)29-12-22-11-23(27)6-7-24(22)32-16-28-15-30-32/h6-11,15-18H,12-14H2,1-5H3,(H,29,33) | PDB
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337476
(CHEMBL1682784 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES Cc1cc(NC2CCCCC2)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C22H25ClN6O/c1-15-9-16(12-20(10-15)26-19-5-3-2-4-6-19)22(30)24-13-17-11-18(23)7-8-21(17)29-14-25-27-28-29/h7-12,14,19,26H,2-6,13H2,1H3,(H,24,30) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337490
(3-(5-chloro-2-methoxyphenethoxy)-N,N-diisobutyl-5-...)Show SMILES COc1ccc(Cl)cc1CCOc1cc(C)cc(c1)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C25H34ClNO3/c1-17(2)15-27(16-18(3)4)25(28)21-11-19(5)12-23(14-21)30-10-9-20-13-22(26)7-8-24(20)29-6/h7-8,11-14,17-18H,9-10,15-16H2,1-6H3 | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337492
(3-(2,2-difluoro-2-(4-methylpyridin-2-yl)ethoxy)-N,...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(OCC(F)(F)c2cc(C)ccn2)c1 Show InChI InChI=1S/C24H32F2N2O2/c1-16(2)13-28(14-17(3)4)23(29)20-9-19(6)10-21(12-20)30-15-24(25,26)22-11-18(5)7-8-27-22/h7-12,16-17H,13-15H2,1-6H3 | PDB
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337482
(CHEMBL1682778 | N1-(2-(1H-tetrazol-1-yl)benzyl)-N3...)Show SMILES CC(C)CN(CC(C)C)C(=O)c1cc(C)cc(c1)C(=O)NCc1ccccc1-n1cnnn1 Show InChI InChI=1S/C25H32N6O2/c1-17(2)14-30(15-18(3)4)25(33)22-11-19(5)10-21(12-22)24(32)26-13-20-8-6-7-9-23(20)31-16-27-28-29-31/h6-12,16-18H,13-15H2,1-5H3,(H,26,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337481
(CHEMBL1682779 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)Show SMILES CN(C)c1ccncc1-c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C23H22ClN7O/c1-15-8-16(20-13-25-7-6-22(20)30(2)3)10-17(9-15)23(32)26-12-18-11-19(24)4-5-21(18)31-14-27-28-29-31/h4-11,13-14H,12H2,1-3H3,(H,26,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50337480
(3-(4-acetylpyridin-3-yl)-N-(5-chloro-2-(1H-tetrazo...)Show SMILES CC(=O)c1ccncc1-c1cc(C)cc(c1)C(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI InChI=1S/C23H19ClN6O2/c1-14-7-16(21-12-25-6-5-20(21)15(2)31)9-17(8-14)23(32)26-11-18-10-19(24)3-4-22(18)30-13-27-28-29-30/h3-10,12-13H,11H2,1-2H3,(H,26,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 1536-40 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.105
BindingDB Entry DOI: 10.7270/Q2V1252F |
More data for this
Ligand-Target Pair | |
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