Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50342746 (2-thienyl-sulfonamido-farnesylcysteine | CHEMBL177...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ... | Bioorg Med Chem Lett 21: 2616-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.078 BindingDB Entry DOI: 10.7270/Q2348KNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50342745 ((R)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ... | Bioorg Med Chem Lett 21: 2616-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.078 BindingDB Entry DOI: 10.7270/Q2348KNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50342747 (3-nitrophenyl-sulfonamido-farnesylcysteine | CHEMB...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ... | Bioorg Med Chem Lett 21: 2616-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.078 BindingDB Entry DOI: 10.7270/Q2348KNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50342748 (4-fluoro-phenyl-sulfonamido-farnesylcysteine | CHE...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ... | Bioorg Med Chem Lett 21: 2616-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.078 BindingDB Entry DOI: 10.7270/Q2348KNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50342744 (CHEMBL1771292 | phenyl-sulfonamido-farnesylcystein...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ... | Bioorg Med Chem Lett 21: 2616-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.078 BindingDB Entry DOI: 10.7270/Q2348KNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50342743 ((R)-2-(2-phenoxyphenylsulfonamido)-3-(3,7,11-trime...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ... | Bioorg Med Chem Lett 21: 2616-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.078 BindingDB Entry DOI: 10.7270/Q2348KNH | |||||||||||
More data for this Ligand-Target Pair |