Compile Data Set for Download or QSAR

Found 56 hits Enz. Inhib. hit(s) with all data for entry = 50033518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346803 (CHEMBL1795862) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C26H26N2O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-23-15-16-25(33-23)34(31,32)28-18-22-8-5-4-7-21(22)17-24(28)26(29)27-30/h4-5,7-12,15-16,24,30H,2-3,6,17-18H2,1H3,(H,27,29)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346797 (CHEMBL1795351) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C18H20N2O4S2/c1-2-3-4-14-5-7-15(8-6-14)9-10-16-11-12-18(25-16)26(23,24)19-13-17(21)20-22/h5-8,11-12,19,22H,2-4,13H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346802 (CHEMBL1795861) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1CSC[C@H]1C(=O)NO |r| Show InChI InChI=1S/C20H22N2O4S3/c1-2-3-4-15-5-7-16(8-6-15)9-10-17-11-12-19(28-17)29(25,26)22-14-27-13-18(22)20(23)21-24/h5-8,11-12,18,24H,2-4,13-14H2,1H3,(H,21,23)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346803 (CHEMBL1795862) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C26H26N2O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-23-15-16-25(33-23)34(31,32)28-18-22-8-5-4-7-21(22)17-24(28)26(29)27-30/h4-5,7-12,15-16,24,30H,2-3,6,17-18H2,1H3,(H,27,29)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346799 (CHEMBL1795858) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346803 (CHEMBL1795862) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C26H26N2O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-23-15-16-25(33-23)34(31,32)28-18-22-8-5-4-7-21(22)17-24(28)26(29)27-30/h4-5,7-12,15-16,24,30H,2-3,6,17-18H2,1H3,(H,27,29)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346803 (CHEMBL1795862) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C26H26N2O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-23-15-16-25(33-23)34(31,32)28-18-22-8-5-4-7-21(22)17-24(28)26(29)27-30/h4-5,7-12,15-16,24,30H,2-3,6,17-18H2,1H3,(H,27,29)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50346801 (CHEMBL1795860) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1csc2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H26N2O4S3/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(32,33)29-24(27(30)28-31)17-21-18-34-25-8-5-4-7-23(21)25/h4-5,7-12,15-16,18,24,29,31H,2-3,6,17H2,1H3,(H,28,30)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346802 (CHEMBL1795861) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1CSC[C@H]1C(=O)NO |r| Show InChI InChI=1S/C20H22N2O4S3/c1-2-3-4-15-5-7-16(8-6-15)9-10-17-11-12-19(28-17)29(25,26)22-14-27-13-18(22)20(23)21-24/h5-8,11-12,18,24H,2-4,13-14H2,1H3,(H,21,23)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346803 (CHEMBL1795862) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C26H26N2O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-23-15-16-25(33-23)34(31,32)28-18-22-8-5-4-7-21(22)17-24(28)26(29)27-30/h4-5,7-12,15-16,24,30H,2-3,6,17-18H2,1H3,(H,27,29)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346797 (CHEMBL1795351) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C18H20N2O4S2/c1-2-3-4-14-5-7-15(8-6-14)9-10-16-11-12-18(25-16)26(23,24)19-13-17(21)20-22/h5-8,11-12,19,22H,2-4,13H2,1H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346802 (CHEMBL1795861) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1CSC[C@H]1C(=O)NO |r| Show InChI InChI=1S/C20H22N2O4S3/c1-2-3-4-15-5-7-16(8-6-15)9-10-17-11-12-19(28-17)29(25,26)22-14-27-13-18(22)20(23)21-24/h5-8,11-12,18,24H,2-4,13-14H2,1H3,(H,21,23)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346797 (CHEMBL1795351) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C18H20N2O4S2/c1-2-3-4-14-5-7-15(8-6-14)9-10-16-11-12-18(25-16)26(23,24)19-13-17(21)20-22/h5-8,11-12,19,22H,2-4,13H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346799 (CHEMBL1795858) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP1 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair				3D Structure (crystal)
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346797 (CHEMBL1795351) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C18H20N2O4S2/c1-2-3-4-14-5-7-15(8-6-14)9-10-16-11-12-18(25-16)26(23,24)19-13-17(21)20-22/h5-8,11-12,19,22H,2-4,13H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346799 (CHEMBL1795858) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50346803 (CHEMBL1795862) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C26H26N2O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-23-15-16-25(33-23)34(31,32)28-18-22-8-5-4-7-21(22)17-24(28)26(29)27-30/h4-5,7-12,15-16,24,30H,2-3,6,17-18H2,1H3,(H,27,29)/t24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346802 (CHEMBL1795861) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1CSC[C@H]1C(=O)NO |r| Show InChI InChI=1S/C20H22N2O4S3/c1-2-3-4-15-5-7-16(8-6-15)9-10-17-11-12-19(28-17)29(25,26)22-14-27-13-18(22)20(23)21-24/h5-8,11-12,18,24H,2-4,13-14H2,1H3,(H,21,23)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346797 (CHEMBL1795351) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C18H20N2O4S2/c1-2-3-4-14-5-7-15(8-6-14)9-10-16-11-12-18(25-16)26(23,24)19-13-17(21)20-22/h5-8,11-12,19,22H,2-4,13H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346801 (CHEMBL1795860) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1csc2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H26N2O4S3/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(32,33)29-24(27(30)28-31)17-21-18-34-25-8-5-4-7-23(21)25/h4-5,7-12,15-16,18,24,29,31H,2-3,6,17H2,1H3,(H,28,30)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50346801 (CHEMBL1795860) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1csc2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H26N2O4S3/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(32,33)29-24(27(30)28-31)17-21-18-34-25-8-5-4-7-23(21)25/h4-5,7-12,15-16,18,24,29,31H,2-3,6,17H2,1H3,(H,28,30)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM50346799 (CHEMBL1795858) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP25 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346799 (CHEMBL1795858) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346802 (CHEMBL1795861) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1CSC[C@H]1C(=O)NO |r| Show InChI InChI=1S/C20H22N2O4S3/c1-2-3-4-15-5-7-16(8-6-15)9-10-17-11-12-19(28-17)29(25,26)22-14-27-13-18(22)20(23)21-24/h5-8,11-12,18,24H,2-4,13-14H2,1H3,(H,21,23)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50346801 (CHEMBL1795860) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1csc2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H26N2O4S3/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(32,33)29-24(27(30)28-31)17-21-18-34-25-8-5-4-7-23(21)25/h4-5,7-12,15-16,18,24,29,31H,2-3,6,17H2,1H3,(H,28,30)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP9 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50346797 (CHEMBL1795351) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C18H20N2O4S2/c1-2-3-4-14-5-7-15(8-6-14)9-10-16-11-12-18(25-16)26(23,24)19-13-17(21)20-22/h5-8,11-12,19,22H,2-4,13H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50346802 (CHEMBL1795861) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1CSC[C@H]1C(=O)NO |r| Show InChI InChI=1S/C20H22N2O4S3/c1-2-3-4-15-5-7-16(8-6-15)9-10-17-11-12-19(28-17)29(25,26)22-14-27-13-18(22)20(23)21-24/h5-8,11-12,18,24H,2-4,13-14H2,1H3,(H,21,23)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50346801 (CHEMBL1795860) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1csc2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H26N2O4S3/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(32,33)29-24(27(30)28-31)17-21-18-34-25-8-5-4-7-23(21)25/h4-5,7-12,15-16,18,24,29,31H,2-3,6,17H2,1H3,(H,28,30)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP8 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50346800 (CHEMBL1795859) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r| Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP1 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50346798 (CHEMBL1795857) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP1 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50346799 (CHEMBL1795858) Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C32H30N2O5S2/c1-2-3-7-23-10-12-24(13-11-23)16-19-28-20-21-30(40-28)41(38,39)34-29(32(36)33-37)22-25-14-17-27(18-15-25)31(35)26-8-5-4-6-9-26/h4-6,8-15,17-18,20-21,29,34,37H,2-3,7,22H2,1H3,(H,33,36)/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human MMP14 by fluorometric assay				Eur J Med Chem 46: 2617-29 (2011) Article DOI: 10.1016/j.ejmech.2011.03.033 BindingDB Entry DOI: 10.7270/Q2RN3864
					More data for this Ligand-Target Pair

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