Found 63 hits Enz. Inhib. hit(s) with all data for entry = 50033629 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348631
(CHEMBL1801109)Show SMILES CS(=O)(=O)N1CCC(CC1)c1cc(Nc2nccn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H20N8O2S2/c1-30(27,28)25-5-2-12(3-6-25)14-8-16(29-24-14)23-17-18-20-11-15(13-9-21-22-10-13)26(18)7-4-19-17/h4,7-12H,2-3,5-6H2,1H3,(H,19,23)(H,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348638
(CHEMBL1800086)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)-c2cccnc2)sn1 Show InChI InChI=1S/C18H14N8S/c1-11-5-16(27-25-11)24-17-18-20-9-15(13-7-21-22-8-13)26(18)10-14(23-17)12-3-2-4-19-6-12/h2-10H,1H3,(H,21,22)(H,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348645
(CHEMBL1801135)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C(=O)N2CCCC2)sn1 Show InChI InChI=1S/C18H18N8OS/c1-11-6-15(28-24-11)23-16-17-19-9-14(12-7-20-21-8-12)26(17)10-13(22-16)18(27)25-4-2-3-5-25/h6-10H,2-5H2,1H3,(H,20,21)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348636
(CHEMBL1801115)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C2CC2)sn1 Show InChI InChI=1S/C16H15N7S/c1-9-4-14(24-22-9)21-15-16-17-7-13(11-5-18-19-6-11)23(16)8-12(20-15)10-2-3-10/h4-8,10H,2-3H2,1H3,(H,18,19)(H,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348631
(CHEMBL1801109)Show SMILES CS(=O)(=O)N1CCC(CC1)c1cc(Nc2nccn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H20N8O2S2/c1-30(27,28)25-5-2-12(3-6-25)14-8-16(29-24-14)23-17-18-20-11-15(13-9-21-22-10-13)26(18)7-4-19-17/h4,7-12H,2-3,5-6H2,1H3,(H,19,23)(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348641
(CHEMBL1801131)Show InChI InChI=1S/C15H15N7S2/c1-3-23-13-8-22-11(10-5-17-18-6-10)7-16-15(22)14(20-13)19-12-4-9(2)21-24-12/h4-8H,3H2,1-2H3,(H,17,18)(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348641
(CHEMBL1801131)Show InChI InChI=1S/C15H15N7S2/c1-3-23-13-8-22-11(10-5-17-18-6-10)7-16-15(22)14(20-13)19-12-4-9(2)21-24-12/h4-8H,3H2,1-2H3,(H,17,18)(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348645
(CHEMBL1801135)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C(=O)N2CCCC2)sn1 Show InChI InChI=1S/C18H18N8OS/c1-11-6-15(28-24-11)23-16-17-19-9-14(12-7-20-21-8-12)26(17)10-13(22-16)18(27)25-4-2-3-5-25/h6-10H,2-5H2,1H3,(H,20,21)(H,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348634
(CHEMBL1801112)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C(F)(F)F)sn1 Show InChI InChI=1S/C14H10F3N7S/c1-7-2-11(25-23-7)22-12-13-18-5-9(8-3-19-20-4-8)24(13)6-10(21-12)14(15,16)17/h2-6H,1H3,(H,19,20)(H,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348639
(CHEMBL1801129)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)S(C)=O)sn1 Show InChI InChI=1S/C14H13N7OS2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)24(2)22/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348635
(CHEMBL1801114)Show InChI InChI=1S/C15H16N8S/c1-9-4-13(24-22-9)21-14-15-17-7-12(10-5-18-19-6-10)23(15)8-11(20-14)2-3-16/h4-8H,2-3,16H2,1H3,(H,18,19)(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348637
(CHEMBL1801128)Show InChI InChI=1S/C14H10N8S/c1-8-2-12(23-21-8)20-13-14-16-6-11(9-4-17-18-5-9)22(14)7-10(3-15)19-13/h2,4-7H,1H3,(H,17,18)(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348633
(CHEMBL1801111)Show SMILES Cc1cc(Nc2nc(CN3CCOCC3)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H20N8OS/c1-12-6-16(28-24-12)23-17-18-19-9-15(13-7-20-21-8-13)26(18)11-14(22-17)10-25-2-4-27-5-3-25/h6-9,11H,2-5,10H2,1H3,(H,20,21)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348636
(CHEMBL1801115)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C2CC2)sn1 Show InChI InChI=1S/C16H15N7S/c1-9-4-14(24-22-9)21-15-16-17-7-13(11-5-18-19-6-11)23(16)8-12(20-15)10-2-3-10/h4-8,10H,2-3H2,1H3,(H,18,19)(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348638
(CHEMBL1800086)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)-c2cccnc2)sn1 Show InChI InChI=1S/C18H14N8S/c1-11-5-16(27-25-11)24-17-18-20-9-15(13-7-21-22-8-13)26(18)10-14(23-17)12-3-2-4-19-6-12/h2-10H,1H3,(H,21,22)(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348632
(CHEMBL1801110)Show SMILES O=S(=O)(N1CCOCC1)c1ccc(Nc2nccn3c(cnc23)-c2cn[nH]c2)cc1 Show InChI InChI=1S/C19H19N7O3S/c27-30(28,25-7-9-29-10-8-25)16-3-1-15(2-4-16)24-18-19-21-13-17(14-11-22-23-12-14)26(19)6-5-20-18/h1-6,11-13H,7-10H2,(H,20,24)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348642
(CHEMBL1801132)Show SMILES CN(C)CCSc1cn2c(cnc2c(Nc2cc(C)ns2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C17H20N8S2/c1-11-6-14(27-23-11)21-16-17-18-9-13(12-7-19-20-8-12)25(17)10-15(22-16)26-5-4-24(2)3/h6-10H,4-5H2,1-3H3,(H,19,20)(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348642
(CHEMBL1801132)Show SMILES CN(C)CCSc1cn2c(cnc2c(Nc2cc(C)ns2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C17H20N8S2/c1-11-6-14(27-23-11)21-16-17-18-9-13(12-7-19-20-8-12)25(17)10-15(22-16)26-5-4-24(2)3/h6-10H,4-5H2,1-3H3,(H,19,20)(H,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348635
(CHEMBL1801114)Show InChI InChI=1S/C15H16N8S/c1-9-4-13(24-22-9)21-14-15-17-7-12(10-5-18-19-6-10)23(15)8-11(20-14)2-3-16/h4-8H,2-3,16H2,1H3,(H,18,19)(H,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348644
(CHEMBL1801134)Show SMILES Cc1cc(Nc2nc(Sc3ccc(F)cc3)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C19H14FN7S2/c1-11-6-16(29-26-11)24-18-19-21-9-15(12-7-22-23-8-12)27(19)10-17(25-18)28-14-4-2-13(20)3-5-14/h2-10H,1H3,(H,22,23)(H,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348643
(CHEMBL1801133)Show SMILES Cc1cc(Nc2nc(SC(C)(C)C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C17H19N7S2/c1-10-5-13(26-23-10)21-15-16-18-8-12(11-6-19-20-7-11)24(16)9-14(22-15)25-17(2,3)4/h5-9H,1-4H3,(H,19,20)(H,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348633
(CHEMBL1801111)Show SMILES Cc1cc(Nc2nc(CN3CCOCC3)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C18H20N8OS/c1-12-6-16(28-24-12)23-17-18-19-9-15(13-7-20-21-8-13)26(18)11-14(22-17)10-25-2-4-27-5-3-25/h6-9,11H,2-5,10H2,1H3,(H,20,21)(H,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348625
(CHEMBL1801103)Show SMILES Cn1cc(cn1)-c1cnc2c(Nc3cc(ns3)C3CCN(CC3)S(C)(=O)=O)nccn12 Show InChI InChI=1S/C19H22N8O2S2/c1-25-12-14(10-22-25)16-11-21-19-18(20-5-8-27(16)19)23-17-9-15(24-30-17)13-3-6-26(7-4-13)31(2,28)29/h5,8-13H,3-4,6-7H2,1-2H3,(H,20,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348632
(CHEMBL1801110)Show SMILES O=S(=O)(N1CCOCC1)c1ccc(Nc2nccn3c(cnc23)-c2cn[nH]c2)cc1 Show InChI InChI=1S/C19H19N7O3S/c27-30(28,25-7-9-29-10-8-25)16-3-1-15(2-4-16)24-18-19-21-13-17(14-11-22-23-12-14)26(19)6-5-20-18/h1-6,11-13H,7-10H2,(H,20,24)(H,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348644
(CHEMBL1801134)Show SMILES Cc1cc(Nc2nc(Sc3ccc(F)cc3)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C19H14FN7S2/c1-11-6-16(29-26-11)24-18-19-21-9-15(12-7-22-23-8-12)27(19)10-17(25-18)28-14-4-2-13(20)3-5-14/h2-10H,1H3,(H,22,23)(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 129 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 167 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of IRAK4 |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348625
(CHEMBL1801103)Show SMILES Cn1cc(cn1)-c1cnc2c(Nc3cc(ns3)C3CCN(CC3)S(C)(=O)=O)nccn12 Show InChI InChI=1S/C19H22N8O2S2/c1-25-12-14(10-22-25)16-11-21-19-18(20-5-8-27(16)19)23-17-9-15(24-30-17)13-3-6-26(7-4-13)31(2,28)29/h5,8-13H,3-4,6-7H2,1-2H3,(H,20,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348639
(CHEMBL1801129)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)S(C)=O)sn1 Show InChI InChI=1S/C14H13N7OS2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)24(2)22/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 187 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Chk1 |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348624
(CHEMBL1801102)Show SMILES Cn1cc(cn1)-c1cnc2c(Nc3cc(ns3)C3CCNCC3)nccn12 Show InChI InChI=1S/C18H20N8S/c1-25-11-13(9-22-25)15-10-21-18-17(20-6-7-26(15)18)23-16-8-14(24-27-16)12-2-4-19-5-3-12/h6-12,19H,2-5H2,1H3,(H,20,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348637
(CHEMBL1801128)Show InChI InChI=1S/C14H10N8S/c1-8-2-12(23-21-8)20-13-14-16-6-11(9-4-17-18-5-9)22(14)7-10(3-15)19-13/h2,4-7H,1H3,(H,17,18)(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 219 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348634
(CHEMBL1801112)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C(F)(F)F)sn1 Show InChI InChI=1S/C14H10F3N7S/c1-7-2-11(25-23-7)22-12-13-18-5-9(8-3-19-20-4-8)24(13)6-10(21-12)14(15,16)17/h2-6H,1H3,(H,19,20)(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 252 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348622
(CHEMBL1801100)Show InChI InChI=1S/C14H13N7S/c1-9-5-12(22-19-9)18-13-14-16-7-11(21(14)4-3-15-13)10-6-17-20(2)8-10/h3-8H,1-2H3,(H,15,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348643
(CHEMBL1801133)Show SMILES Cc1cc(Nc2nc(SC(C)(C)C)cn3c(cnc23)-c2cn[nH]c2)sn1 Show InChI InChI=1S/C17H19N7S2/c1-10-5-13(26-23-10)21-15-16-18-8-12(11-6-19-20-7-11)24(16)9-14(22-15)25-17(2,3)4/h5-9H,1-4H3,(H,19,20)(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 272 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 468 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of LCK |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348622
(CHEMBL1801100)Show InChI InChI=1S/C14H13N7S/c1-9-5-12(22-19-9)18-13-14-16-7-11(21(14)4-3-15-13)10-6-17-20(2)8-10/h3-8H,1-2H3,(H,15,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348640
(CHEMBL1801130)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)S(C)(=O)=O)sn1 Show InChI InChI=1S/C14H13N7O2S2/c1-8-3-11(24-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)25(2,22)23/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 603 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348623
(CHEMBL1801101)Show InChI InChI=1S/C16H17N7S/c1-10(2)12-6-14(24-21-12)20-15-16-18-8-13(23(16)5-4-17-15)11-7-19-22(3)9-11/h4-10H,1-3H3,(H,17,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348623
(CHEMBL1801101)Show InChI InChI=1S/C16H17N7S/c1-10(2)12-6-14(24-21-12)20-15-16-18-8-13(23(16)5-4-17-15)11-7-19-22(3)9-11/h4-10H,1-3H3,(H,17,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 785 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PLK3 |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of RSK2 |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348624
(CHEMBL1801102)Show SMILES Cn1cc(cn1)-c1cnc2c(Nc3cc(ns3)C3CCNCC3)nccn12 Show InChI InChI=1S/C18H20N8S/c1-25-11-13(9-22-25)15-10-21-18-17(20-6-7-26(15)18)23-16-8-14(24-27-16)12-2-4-19-5-3-12/h6-12,19H,2-5H2,1H3,(H,20,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of CSNK1d |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Cdk2 |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348628
(CHEMBL1801106)Show InChI InChI=1S/C15H14N6S/c1-10-5-13(22-9-10)19-14-15-17-7-12(21(15)4-3-16-14)11-6-18-20(2)8-11/h3-9H,1-2H3,(H,16,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348640
(CHEMBL1801130)Show SMILES Cc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)S(C)(=O)=O)sn1 Show InChI InChI=1S/C14H13N7O2S2/c1-8-3-11(24-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)25(2,22)23/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50348628
(CHEMBL1801106)Show InChI InChI=1S/C15H14N6S/c1-10-5-13(22-9-10)19-14-15-17-7-12(21(15)4-3-16-14)11-6-18-20(2)8-11/h3-9H,1-2H3,(H,16,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50348630
(CHEMBL1801108)Show SMILES CN(C)S(=O)(=O)c1ccc(Nc2nccn3c(cnc23)-c2cnn(C)c2)cc1 Show InChI InChI=1S/C18H19N7O2S/c1-23(2)28(26,27)15-6-4-14(5-7-15)22-17-18-20-11-16(25(18)9-8-19-17)13-10-21-24(3)12-13/h4-12H,1-3H3,(H,19,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assay |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50348621
(CHEMBL1270795)Show InChI InChI=1S/C14H13N7S2/c1-8-3-11(23-20-8)18-13-14-15-6-10(9-4-16-17-5-9)21(14)7-12(19-13)22-2/h3-7H,1-2H3,(H,16,17)(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of EGFR |
Bioorg Med Chem Lett 20: 5170-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.008 BindingDB Entry DOI: 10.7270/Q2Q81DGH |
More data for this Ligand-Target Pair | |