Compile Data Set for Download or QSAR

Found 106 hits Enz. Inhib. hit(s) with all data for entry = 50033719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350167 (CHEMBL1814741) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H31ClN4O2/c30-25-12-10-22(11-13-25)28(21-6-2-1-3-7-21)33-16-14-32(15-17-33)27(35)18-26(31)29(36)34-19-23-8-4-5-9-24(23)20-34/h1-13,26,28H,14-20,31H2/t26-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350175 (CHEMBL1814749) Show SMILES C[C@@H]1CN(CCN1C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H32F2N4O2/c1-20-17-34(28(37)16-27(33)30(38)35-18-23-4-2-3-5-24(23)19-35)14-15-36(20)29(21-6-10-25(31)11-7-21)22-8-12-26(32)13-9-22/h2-13,20,27,29H,14-19,33H2,1H3/t20-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50146972 ((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...) Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C16H24ClN3O/c17-14-6-4-13(5-7-14)12-19-9-8-15(18)16(21)20-10-2-1-3-11-20/h4-7,15,19H,1-3,8-12,18H2/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP2				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50225074 ((1S,3S,5S)-2-[(S)-2-amino-2-(3-hydroxy-adamantan-1...) Show SMILES N[C@H](C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N)C12CC3CC(CC(O)(C3)C1)C2 |TLB:1:12:15:20.18.17,THB:13:14:17:22.12.21,13:12:15.14.20:17,21:12:15:20.18.17,21:18:15:22.13.12,19:18:15:22.13.12| Show InChI InChI=1S/C18H25N3O2/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17/h10-15,23H,1-7,9,20H2/t10?,11?,12-,13+,14+,15-,17?,18?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP4				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350168 (CHEMBL1814740) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI InChI=1S/C29H30ClFN4O2/c30-24-9-6-21(7-10-24)28(20-4-2-1-3-5-20)34-14-12-33(13-15-34)27(36)17-26(32)29(37)35-18-22-8-11-25(31)16-23(22)19-35/h1-11,16,26,28H,12-15,17-19,32H2/t26-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350166 (CHEMBL1814739) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccc(F)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O2/c30-23-6-1-19(2-7-23)28(20-3-8-24(31)9-4-20)35-13-11-34(12-14-35)27(37)16-26(33)29(38)36-17-21-5-10-25(32)15-22(21)18-36/h1-10,15,26,28H,11-14,16-18,33H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350167 (CHEMBL1814741) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H31ClN4O2/c30-25-12-10-22(11-13-25)28(21-6-2-1-3-7-21)33-16-14-32(15-17-33)27(35)18-26(31)29(36)34-19-23-8-4-5-9-24(23)20-34/h1-13,26,28H,14-20,31H2/t26-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350169 (CHEMBL1814633 | US11096924, DASH-inhibitors 4160 (...) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H30F2N4O2/c30-24-9-5-20(6-10-24)28(21-7-11-25(31)12-8-21)34-15-13-33(14-16-34)27(36)17-26(32)29(37)35-18-22-3-1-2-4-23(22)19-35/h1-12,26,28H,13-19,32H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350169 (CHEMBL1814633 | US11096924, DASH-inhibitors 4160 (...) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H30F2N4O2/c30-24-9-5-20(6-10-24)28(21-7-11-25(31)12-8-21)34-15-13-33(14-16-34)27(36)17-26(32)29(37)35-18-22-3-1-2-4-23(22)19-35/h1-12,26,28H,13-19,32H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP8				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350170 (CHEMBL1814753) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(=O)c1cccc(c1)-c1ccccc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H30N4O3/c30-26(29(36)33-19-24-9-4-5-10-25(24)20-33)18-27(34)31-13-15-32(16-14-31)28(35)23-12-6-11-22(17-23)21-7-2-1-3-8-21/h1-12,17,26H,13-16,18-20,30H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350172 (CHEMBL1814748) Show SMILES C[C@H]1CN(CCN1C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H32F2N4O2/c1-20-17-34(28(37)16-27(33)30(38)35-18-23-4-2-3-5-24(23)19-35)14-15-36(20)29(21-6-10-25(31)11-7-21)22-8-12-26(32)13-9-22/h2-13,20,27,29H,14-19,33H2,1H3/t20-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350187 (CHEMBL1814759) Show SMILES N[C@@H](CC(=O)NC1CCN(C1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H30F2N4O2/c30-23-9-5-19(6-10-23)28(20-7-11-24(31)12-8-20)34-14-13-25(18-34)33-27(36)15-26(32)29(37)35-16-21-3-1-2-4-22(21)17-35/h1-12,25-26,28H,13-18,32H2,(H,33,36)/t25?,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11162 ((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP4				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350175 (CHEMBL1814749) Show SMILES C[C@@H]1CN(CCN1C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H32F2N4O2/c1-20-17-34(28(37)16-27(33)30(38)35-18-23-4-2-3-5-24(23)19-35)14-15-36(20)29(21-6-10-25(31)11-7-21)22-8-12-26(32)13-9-22/h2-13,20,27,29H,14-19,33H2,1H3/t20-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50350169 (CHEMBL1814633 | US11096924, DASH-inhibitors 4160 (...) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H30F2N4O2/c30-24-9-5-20(6-10-24)28(21-7-11-25(31)12-8-21)34-15-13-33(14-16-34)27(36)17-26(32)29(37)35-18-22-3-1-2-4-23(22)19-35/h1-12,26,28H,13-19,32H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP9				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350171 (CHEMBL1814742) Show SMILES N[C@@H](CC(=O)N1CCN(Cc2ccc3ccccc3c2)CC1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C27H30N4O2/c28-25(27(33)31-18-23-7-3-4-8-24(23)19-31)16-26(32)30-13-11-29(12-14-30)17-20-9-10-21-5-1-2-6-22(21)15-20/h1-10,15,25H,11-14,16-19,28H2/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350178 (CHEMBL1814747) Show SMILES N[C@@H](CC(=O)N1CCN(Cc2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H27FN4O2/c24-20-7-5-17(6-8-20)14-26-9-11-27(12-10-26)22(29)13-21(25)23(30)28-15-18-3-1-2-4-19(18)16-28/h1-8,21H,9-16,25H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350174 (CHEMBL1814745) Show SMILES N[C@@H](CC(=O)N1CCCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H32F2N4O2/c31-25-10-6-21(7-11-25)29(22-8-12-26(32)13-9-22)35-15-3-14-34(16-17-35)28(37)18-27(33)30(38)36-19-23-4-1-2-5-24(23)20-36/h1-2,4-13,27,29H,3,14-20,33H2/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N |r,TLB:9:8:6:3.2.4,4:3:10:7.6.5,4:5:10:3.2.9,THB:9:3:6:10.7.8,11:8:6:3.2.4| Show InChI InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP4				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350173 (CHEMBL1814743) Show SMILES N[C@@H](CC(=O)N1CCN(Cc2ccc(cc2)-c2ccccc2C#N)CC1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H31N5O2/c31-18-24-5-3-4-8-27(24)23-11-9-22(10-12-23)19-33-13-15-34(16-14-33)29(36)17-28(32)30(37)35-20-25-6-1-2-7-26(25)21-35/h1-12,28H,13-17,19-21,32H2/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350176 (CHEMBL1814751) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(=O)C1c2ccccc2-c2ccccc12)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H30N4O3/c31-26(29(36)34-18-20-7-1-2-8-21(20)19-34)17-27(35)32-13-15-33(16-14-32)30(37)28-24-11-5-3-9-22(24)23-10-4-6-12-25(23)28/h1-12,26,28H,13-19,31H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350190 (CHEMBL1814757) Show SMILES N[C@@H](CC(=O)NC(c1ccccc1)c1ccccc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C25H25N3O2/c26-22(25(30)28-16-20-13-7-8-14-21(20)17-28)15-23(29)27-24(18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-14,22,24H,15-17,26H2,(H,27,29)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350181 (CHEMBL1814746) Show SMILES N[C@@H](CC(=O)N1C[C@H]2C[C@@H]1CN2C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r,TLB:3:5:11.10:8| Show InChI InChI=1S/C30H30F2N4O2/c31-23-9-5-19(6-10-23)29(20-7-11-24(32)12-8-20)36-18-25-13-26(36)17-35(25)28(37)14-27(33)30(38)34-15-21-3-1-2-4-22(21)16-34/h1-12,25-27,29H,13-18,33H2/t25-,26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350177 (CHEMBL1814752) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H30Cl2N4O3/c31-24-9-5-20(6-10-24)28(21-7-11-25(32)12-8-21)30(39)35-15-13-34(14-16-35)27(37)17-26(33)29(38)36-18-22-3-1-2-4-23(22)19-36/h1-12,26,28H,13-19,33H2/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350188 (CHEMBL1814761) Show SMILES COc1ccc2ccccc2c1CN[C@@H]1CN[C@@H](C1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C25H27N3O2/c1-30-24-11-10-17-6-4-5-9-21(17)22(24)14-26-20-12-23(27-13-20)25(29)28-15-18-7-2-3-8-19(18)16-28/h2-11,20,23,26-27H,12-16H2,1H3/t20-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350179 (CHEMBL1811949) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(CC1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C31H44N4O4S/c1-20(2)25-15-26(21(3)4)30(27(16-25)22(5)6)40(38,39)35-13-11-33(12-14-35)29(36)17-28(32)31(37)34-18-23-9-7-8-10-24(23)19-34/h7-10,15-16,20-22,28H,11-14,17-19,32H2,1-6H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350182 (CHEMBL1814750) Show SMILES N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)C(=O)C1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H28F2N4O3/c30-23-9-5-19(6-10-23)28(20-7-11-24(31)12-8-20)35-14-13-33(18-27(35)37)26(36)15-25(32)29(38)34-16-21-3-1-2-4-22(21)17-34/h1-12,25,28H,13-18,32H2/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350189 (CHEMBL1814758) Show SMILES N[C@@H](CC(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C25H23F2N3O2/c26-20-9-5-16(6-10-20)24(17-7-11-21(27)12-8-17)29-23(31)13-22(28)25(32)30-14-18-3-1-2-4-19(18)15-30/h1-12,22,24H,13-15,28H2,(H,29,31)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N |r,TLB:9:8:6:3.2.4,4:3:10:7.6.5,4:5:10:3.2.9,THB:9:3:6:10.7.8,11:8:6:3.2.4| Show InChI InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP9				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350180 (CHEMBL1814756) Show SMILES N[C@@H](CC(=O)N1CCC(CC1)N1CCCCC1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C22H32N4O2/c23-20(22(28)26-15-17-6-2-3-7-18(17)16-26)14-21(27)25-12-8-19(9-13-25)24-10-4-1-5-11-24/h2-3,6-7,19-20H,1,4-5,8-16,23H2/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350184 (CHEMBL1814755) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H30F2N4O3/c31-23-11-7-19(8-12-23)28(20-9-13-24(32)14-10-20)34-29(38)26-6-3-15-36(26)27(37)16-25(33)30(39)35-17-21-4-1-2-5-22(21)18-35/h1-2,4-5,7-14,25-26,28H,3,6,15-18,33H2,(H,34,38)/t25-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350183 (CHEMBL1814634) Show SMILES N[C@@H](CCC(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H32F2N4O2/c31-25-9-5-21(6-10-25)29(22-7-11-26(32)12-8-22)35-17-15-34(16-18-35)28(37)14-13-27(33)30(38)36-19-23-3-1-2-4-24(23)20-36/h1-12,27,29H,13-20,33H2/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350186 (CHEMBL1814760) Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H24N4O/c28-23(27-14-17-5-1-2-6-18(17)15-27)22-11-19(13-26-22)25-12-16-9-10-24-21-8-4-3-7-20(16)21/h1-10,19,22,25-26H,11-15H2/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350176 (CHEMBL1814751) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(=O)C1c2ccccc2-c2ccccc12)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H30N4O3/c31-26(29(36)34-18-20-7-1-2-8-21(20)19-34)17-27(35)32-13-15-33(16-14-32)30(37)28-24-11-5-3-9-22(24)23-10-4-6-12-25(23)28/h1-12,26,28H,13-19,31H2/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350184 (CHEMBL1814755) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H30F2N4O3/c31-23-11-7-19(8-12-23)28(20-9-13-24(32)14-10-20)34-29(38)26-6-3-15-36(26)27(37)16-25(33)30(39)35-17-21-4-1-2-5-22(21)18-35/h1-2,4-5,7-14,25-26,28H,3,6,15-18,33H2,(H,34,38)/t25-,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350174 (CHEMBL1814745) Show SMILES N[C@@H](CC(=O)N1CCCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H32F2N4O2/c31-25-10-6-21(7-11-25)29(22-8-12-26(32)13-9-22)35-15-3-14-34(16-17-35)28(37)18-27(33)30(38)36-19-23-4-1-2-5-24(23)20-36/h1-2,4-13,27,29H,3,14-20,33H2/t27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350186 (CHEMBL1814760) Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H24N4O/c28-23(27-14-17-5-1-2-6-18(17)15-27)22-11-19(13-26-22)25-12-16-9-10-24-21-8-4-3-7-20(16)21/h1-10,19,22,25-26H,11-15H2/t19-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350187 (CHEMBL1814759) Show SMILES N[C@@H](CC(=O)NC1CCN(C1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C29H30F2N4O2/c30-23-9-5-19(6-10-23)28(20-7-11-24(31)12-8-20)34-14-13-25(18-34)33-27(36)15-26(32)29(37)35-16-21-3-1-2-4-22(21)17-35/h1-12,25-26,28H,13-18,32H2,(H,33,36)/t25?,26-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350185 (CHEMBL1814737) Show SMILES N[C@@H](CCC(=O)N1CCN(Cc2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C24H29FN4O2/c25-21-7-5-18(6-8-21)15-27-11-13-28(14-12-27)23(30)10-9-22(26)24(31)29-16-19-3-1-2-4-20(19)17-29/h1-8,22H,9-17,26H2/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350189 (CHEMBL1814758) Show SMILES N[C@@H](CC(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C25H23F2N3O2/c26-20-9-5-16(6-10-20)24(17-7-11-21(27)12-8-17)29-23(31)13-22(28)25(32)30-14-18-3-1-2-4-19(18)15-30/h1-12,22,24H,13-15,28H2,(H,29,31)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350191 (CHEMBL1814754) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1C(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C34H37F2N5O3/c35-27-11-7-23(8-12-27)32(24-9-13-28(36)14-10-24)38-16-18-39(19-17-38)34(44)30-6-3-15-41(30)31(42)20-29(37)33(43)40-21-25-4-1-2-5-26(25)22-40/h1-2,4-5,7-14,29-30,32H,3,6,15-22,37H2/t29-,30-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N |r,TLB:9:8:6:3.2.4,4:3:10:7.6.5,4:5:10:3.2.9,THB:9:3:6:10.7.8,11:8:6:3.2.4| Show InChI InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of DPP8				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350190 (CHEMBL1814757) Show SMILES N[C@@H](CC(=O)NC(c1ccccc1)c1ccccc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C25H25N3O2/c26-22(25(30)28-16-20-13-7-8-14-21(20)17-28)15-23(29)27-24(18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-14,22,24H,15-17,26H2,(H,27,29)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350165 (CHEMBL1814738) Show SMILES Fc1ccc(cc1)C(N1CCN(CC1)C(=O)CCC(=O)N1Cc2ccccc2C1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F2N3O2/c30-25-9-5-21(6-10-25)29(22-7-11-26(31)12-8-22)33-17-15-32(16-18-33)27(35)13-14-28(36)34-19-23-3-1-2-4-24(23)20-34/h1-12,29H,13-20H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350193 (CHEMBL1814632) Show SMILES N[C@@H](CC(=O)NC12CC3CC(CC(O)(C3)C1)C2)C(=O)N1Cc2ccccc2C1 |r,TLB:5:6:9:14.12.11,THB:7:8:11:16.6.15,7:6:9.8.14:11,5:6:9.8.14:11,15:6:9:14.12.11,15:12:9:16.7.6,13:12:9:16.7.6| Show InChI InChI=1S/C22H29N3O3/c23-18(20(27)25-11-16-3-1-2-4-17(16)12-25)6-19(26)24-21-7-14-5-15(8-21)10-22(28,9-14)13-21/h1-4,14-15,18,28H,5-13,23H2,(H,24,26)/t14?,15?,18-,21?,22?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350185 (CHEMBL1814737) Show SMILES N[C@@H](CCC(=O)N1CCN(Cc2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C24H29FN4O2/c25-21-7-5-18(6-8-21)15-27-11-13-28(14-12-27)23(30)10-9-22(26)24(31)29-16-19-3-1-2-4-20(19)17-29/h1-8,22H,9-17,26H2/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350193 (CHEMBL1814632) Show SMILES N[C@@H](CC(=O)NC12CC3CC(CC(O)(C3)C1)C2)C(=O)N1Cc2ccccc2C1 |r,TLB:5:6:9:14.12.11,THB:7:8:11:16.6.15,7:6:9.8.14:11,5:6:9.8.14:11,15:6:9:14.12.11,15:12:9:16.7.6,13:12:9:16.7.6| Show InChI InChI=1S/C22H29N3O3/c23-18(20(27)25-11-16-3-1-2-4-17(16)12-25)6-19(26)24-21-7-14-5-15(8-21)10-22(28,9-14)13-21/h1-4,14-15,18,28H,5-13,23H2,(H,24,26)/t14?,15?,18-,21?,22?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50350188 (CHEMBL1814761) Show SMILES COc1ccc2ccccc2c1CN[C@@H]1CN[C@@H](C1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C25H27N3O2/c1-30-24-11-10-17-6-4-5-9-21(17)22(24)14-26-20-12-23(27-13-20)25(29)28-15-18-7-2-3-8-19(18)16-28/h2-11,20,23,26-27H,12-16H2,1H3/t20-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50350177 (CHEMBL1814752) Show SMILES N[C@@H](CC(=O)N1CCN(CC1)C(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C30H30Cl2N4O3/c31-24-9-5-20(6-10-24)28(21-7-11-25(32)12-8-21)30(39)35-15-13-34(14-16-35)27(37)17-26(33)29(38)36-18-22-3-1-2-4-23(22)19-36/h1-12,26,28H,13-19,33H2/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50350186 (CHEMBL1814760) Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H24N4O/c28-23(27-14-17-5-1-2-6-18(17)15-27)22-11-19(13-26-22)25-12-16-9-10-24-21-8-4-3-7-20(16)21/h1-10,19,22,25-26H,11-15H2/t19-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair

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