Found 138 hits Enz. Inhib. hit(s) with all data for entry = 50033728 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350352
(CHEMBL1813275)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(C)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C29H27FN2O5/c1-17-12-20(36-16-21-15-31(3)26-6-4-5-7-27(26)37-21)9-10-22(17)29(35)32-18(2)23(14-28(33)34)24-13-19(30)8-11-25(24)32/h4-13,21H,14-16H2,1-3H3,(H,33,34)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350350
(CHEMBL1813120)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C29H28N2O5/c1-18-14-20(35-17-21-16-30(3)26-10-6-7-11-27(26)36-21)12-13-22(18)29(34)31-19(2)24(15-28(32)33)23-8-4-5-9-25(23)31/h4-14,21H,15-17H2,1-3H3,(H,32,33)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350371
(CHEMBL1813122)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(F)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)20-7-3-4-8-24(20)31(17)28(34)21-12-11-18(13-23(21)29)35-16-19-15-30(2)25-9-5-6-10-26(25)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350354
(CHEMBL1813277)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(F)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H24F2N2O5/c1-16-21(13-27(33)34)22-11-17(29)7-10-24(22)32(16)28(35)20-9-8-18(12-23(20)30)36-15-19-14-31(2)25-5-3-4-6-26(25)37-19/h3-12,19H,13-15H2,1-2H3,(H,33,34)/t19-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350351
(CHEMBL1813121)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(Cl)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25ClN2O5/c1-17-22(14-27(32)33)20-7-3-4-8-24(20)31(17)28(34)21-12-11-18(13-23(21)29)35-16-19-15-30(2)25-9-5-6-10-26(25)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350366
(CHEMBL1813287)Show SMILES CCN1[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Cc2ccccc12 |r| Show InChI InChI=1S/C30H30N2O4/c1-4-31-22(16-21-9-5-7-11-27(21)31)18-36-23-13-14-24(19(2)15-23)30(35)32-20(3)26(17-29(33)34)25-10-6-8-12-28(25)32/h5-15,22H,4,16-18H2,1-3H3,(H,33,34)/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350353
(CHEMBL1813276)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(Cl)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H24ClFN2O5/c1-16-21(13-27(33)34)22-11-17(30)7-10-24(22)32(16)28(35)20-9-8-18(12-23(20)29)36-15-19-14-31(2)25-5-3-4-6-26(25)37-19/h3-12,19H,13-15H2,1-2H3,(H,33,34)/t19-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350361
(CHEMBL1813289)Show SMILES Cc1c(CC(O)=O)c2cc(F)ccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc23)cc1C |r| Show InChI InChI=1S/C28H24FNO5/c1-16-11-20(34-14-18-15-35-26-6-4-3-5-22(18)26)8-9-21(16)28(33)30-17(2)23(13-27(31)32)24-12-19(29)7-10-25(24)30/h3-12,18H,13-15H2,1-2H3,(H,31,32)/t18-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350369
(CHEMBL1813118)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350362
(CHEMBL1813284)Show SMILES Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(OC[C@@H]2Cc3ccccc3O2)cc1C |r| Show InChI InChI=1S/C28H25NO5/c1-17-13-20(33-16-21-14-19-7-3-6-10-26(19)34-21)11-12-22(17)28(32)29-18(2)24(15-27(30)31)23-8-4-5-9-25(23)29/h3-13,21H,14-16H2,1-2H3,(H,30,31)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350349
(CHEMBL1813115)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H26N2O5/c1-18-23(15-27(31)32)22-7-3-4-8-24(22)30(18)28(33)19-11-13-20(14-12-19)34-17-21-16-29(2)25-9-5-6-10-26(25)35-21/h3-14,21H,15-17H2,1-2H3,(H,31,32)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350370
(CHEMBL1813119)Show SMILES COc1ccc2n(C(=O)c3ccc(OC[C@@H]4CN(C)c5ccccc5O4)cc3)c(C)c(CC(O)=O)c2c1 |r| Show InChI InChI=1S/C29H28N2O6/c1-18-23(15-28(32)33)24-14-21(35-3)12-13-25(24)31(18)29(34)19-8-10-20(11-9-19)36-17-22-16-30(2)26-6-4-5-7-27(26)37-22/h4-14,22H,15-17H2,1-3H3,(H,32,33)/t22-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 9.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350358
(CHEMBL1813281)Show SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C30H29FN2O5/c1-17-12-28(37-16-21-15-32(4)26-7-5-6-8-27(26)38-21)18(2)11-22(17)30(36)33-19(3)23(14-29(34)35)24-13-20(31)9-10-25(24)33/h5-13,21H,14-16H2,1-4H3,(H,34,35)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50152515
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12 Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350365
(CHEMBL1813288)Show SMILES CCN1C(COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Cc2ccccc12 Show InChI InChI=1S/C30H30N2O4/c1-4-31-22(16-21-9-5-7-11-27(21)31)18-36-23-13-14-24(19(2)15-23)30(35)32-20(3)26(17-29(33)34)25-10-6-8-12-28(25)32/h5-15,22H,4,16-18H2,1-3H3,(H,33,34) | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350359
(CHEMBL1813282)Show SMILES Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc3O2)cc1C |r| Show InChI InChI=1S/C28H25NO6/c1-17-13-19(33-15-20-16-34-25-9-5-6-10-26(25)35-20)11-12-21(17)28(32)29-18(2)23(14-27(30)31)22-7-3-4-8-24(22)29/h3-13,20H,14-16H2,1-2H3,(H,30,31)/t20-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350367
(CHEMBL1813116)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(C)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C29H28N2O5/c1-18-8-13-25-24(14-18)23(15-28(32)33)19(2)31(25)29(34)20-9-11-21(12-10-20)35-17-22-16-30(3)26-6-4-5-7-27(26)36-22/h4-14,22H,15-17H2,1-3H3,(H,32,33)/t22-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350368
(CHEMBL1813117)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(Cl)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25ClN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50152515
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12 Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350360
(CHEMBL1813283)Show SMILES Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc23)cc1C |r| Show InChI InChI=1S/C28H25NO5/c1-17-13-20(33-15-19-16-34-26-10-6-4-7-22(19)26)11-12-21(17)28(32)29-18(2)24(14-27(30)31)23-8-3-5-9-25(23)29/h3-13,19H,14-16H2,1-2H3,(H,30,31)/t19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350368
(CHEMBL1813117)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(Cl)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25ClN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350355
(CHEMBL1813278)Show SMILES CN1C[C@@H](COc2ccc(cc2C)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C29H27FN2O5/c1-17-12-19(8-11-26(17)36-16-21-15-31(3)25-6-4-5-7-27(25)37-21)29(35)32-18(2)22(14-28(33)34)23-13-20(30)9-10-24(23)32/h4-13,21H,14-16H2,1-3H3,(H,33,34)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350372
(CHEMBL1813123)Show SMILES CN1C[C@@H](COc2ccc(cc2C)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C29H28N2O5/c1-18-14-20(29(34)31-19(2)23(15-28(32)33)22-8-4-5-9-24(22)31)12-13-26(18)35-17-21-16-30(3)25-10-6-7-11-27(25)36-21/h4-14,21H,15-17H2,1-3H3,(H,32,33)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350373
(CHEMBL1813124)Show SMILES CN1C[C@@H](COc2ccc(cc2Cl)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25ClN2O5/c1-17-21(14-27(32)33)20-7-3-4-8-23(20)31(17)28(34)18-11-12-25(22(29)13-18)35-16-19-15-30(2)24-9-5-6-10-26(24)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350351
(CHEMBL1813121)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(Cl)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25ClN2O5/c1-17-22(14-27(32)33)20-7-3-4-8-24(20)31(17)28(34)21-12-11-18(13-23(21)29)35-16-19-15-30(2)25-9-5-6-10-26(25)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350358
(CHEMBL1813281)Show SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C30H29FN2O5/c1-17-12-28(37-16-21-15-32(4)26-7-5-6-8-27(26)38-21)18(2)11-22(17)30(36)33-19(3)23(14-29(34)35)24-13-20(31)9-10-25(24)33/h5-13,21H,14-16H2,1-4H3,(H,34,35)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350377
(CHEMBL1813274)Show SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C30H30N2O5/c1-18-14-28(36-17-21-16-31(4)26-11-7-8-12-27(26)37-21)19(2)13-23(18)30(35)32-20(3)24(15-29(33)34)22-9-5-6-10-25(22)32/h5-14,21H,15-17H2,1-4H3,(H,33,34)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350376
(CHEMBL1813273)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2C)Oc2ccccc12 |r| Show InChI InChI=1S/C30H30N2O5/c1-18-19(2)27(36-17-21-16-31(4)26-11-7-8-12-28(26)37-21)14-13-22(18)30(35)32-20(3)24(15-29(33)34)23-9-5-6-10-25(23)32/h5-14,21H,15-17H2,1-4H3,(H,33,34)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50152515
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12 Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350371
(CHEMBL1813122)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(F)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)20-7-3-4-8-24(20)31(17)28(34)21-12-11-18(13-23(21)29)35-16-19-15-30(2)25-9-5-6-10-26(25)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350352
(CHEMBL1813275)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(C)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C29H27FN2O5/c1-17-12-20(36-16-21-15-31(3)26-6-4-5-7-27(26)37-21)9-10-22(17)29(35)32-18(2)23(14-28(33)34)24-13-19(30)8-11-25(24)32/h4-13,21H,14-16H2,1-3H3,(H,33,34)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350350
(CHEMBL1813120)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C29H28N2O5/c1-18-14-20(35-17-21-16-30(3)26-10-6-7-11-27(26)36-21)12-13-22(18)29(34)31-19(2)24(15-28(32)33)23-8-4-5-9-25(23)31/h4-14,21H,15-17H2,1-3H3,(H,32,33)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350372
(CHEMBL1813123)Show SMILES CN1C[C@@H](COc2ccc(cc2C)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C29H28N2O5/c1-18-14-20(29(34)31-19(2)23(15-28(32)33)22-8-4-5-9-24(22)31)12-13-26(18)35-17-21-16-30(3)25-10-6-7-11-27(25)36-21/h4-14,21H,15-17H2,1-3H3,(H,32,33)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350355
(CHEMBL1813278)Show SMILES CN1C[C@@H](COc2ccc(cc2C)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C29H27FN2O5/c1-17-12-19(8-11-26(17)36-16-21-15-31(3)25-6-4-5-7-27(25)37-21)29(35)32-18(2)22(14-28(33)34)23-13-20(30)9-10-24(23)32/h4-13,21H,14-16H2,1-3H3,(H,33,34)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350353
(CHEMBL1813276)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(Cl)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H24ClFN2O5/c1-16-21(13-27(33)34)22-11-17(30)7-10-24(22)32(16)28(35)20-9-8-18(12-23(20)29)36-15-19-14-31(2)25-5-3-4-6-26(25)37-19/h3-12,19H,13-15H2,1-2H3,(H,33,34)/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350349
(CHEMBL1813115)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H26N2O5/c1-18-23(15-27(31)32)22-7-3-4-8-24(22)30(18)28(33)19-11-13-20(14-12-19)34-17-21-16-29(2)25-9-5-6-10-26(25)35-21/h3-14,21H,15-17H2,1-2H3,(H,31,32)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50350349
(CHEMBL1813115)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H26N2O5/c1-18-23(15-27(31)32)22-7-3-4-8-24(22)30(18)28(33)19-11-13-20(14-12-19)34-17-21-16-29(2)25-9-5-6-10-26(25)35-21/h3-14,21H,15-17H2,1-2H3,(H,31,32)/t21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350374
(CHEMBL1813125)Show SMILES CN1C[C@@H](COc2ccc(cc2F)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-21(14-27(32)33)20-7-3-4-8-23(20)31(17)28(34)18-11-12-25(22(29)13-18)35-16-19-15-30(2)24-9-5-6-10-26(24)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350357
(CHEMBL1813280)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(C)c2C)Oc2ccccc12 |r| Show InChI InChI=1S/C30H29FN2O5/c1-17-18(2)27(37-16-21-15-32(4)26-7-5-6-8-28(26)38-21)12-10-22(17)30(36)33-19(3)23(14-29(34)35)24-13-20(31)9-11-25(24)33/h5-13,21H,14-16H2,1-4H3,(H,34,35)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350374
(CHEMBL1813125)Show SMILES CN1C[C@@H](COc2ccc(cc2F)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-21(14-27(32)33)20-7-3-4-8-23(20)31(17)28(34)18-11-12-25(22(29)13-18)35-16-19-15-30(2)24-9-5-6-10-26(24)36-19/h3-13,19H,14-16H2,1-2H3,(H,32,33)/t19-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50350369
(CHEMBL1813118)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50152515
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12 Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SQ29548 from human TP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350362
(CHEMBL1813284)Show SMILES Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(OC[C@@H]2Cc3ccccc3O2)cc1C |r| Show InChI InChI=1S/C28H25NO5/c1-17-13-20(33-16-21-14-19-7-3-6-10-26(19)34-21)11-12-22(17)28(32)29-18(2)24(15-27(30)31)23-8-4-5-9-25(23)29/h3-13,21H,14-16H2,1-2H3,(H,30,31)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50350370
(CHEMBL1813119)Show SMILES COc1ccc2n(C(=O)c3ccc(OC[C@@H]4CN(C)c5ccccc5O4)cc3)c(C)c(CC(O)=O)c2c1 |r| Show InChI InChI=1S/C29H28N2O6/c1-18-23(15-28(32)33)24-14-21(35-3)12-13-25(24)31(18)29(34)19-8-10-20(11-9-19)36-17-22-16-30(2)26-6-4-5-7-27(26)37-22/h4-14,22H,15-17H2,1-3H3,(H,32,33)/t22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350369
(CHEMBL1813118)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(F)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50350354
(CHEMBL1813277)Show SMILES CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4cc(F)ccc34)c(F)c2)Oc2ccccc12 |r| Show InChI InChI=1S/C28H24F2N2O5/c1-16-21(13-27(33)34)22-11-17(29)7-10-24(22)32(16)28(35)20-9-8-18(12-23(20)30)36-15-19-14-31(2)25-5-3-4-6-26(25)37-19/h3-12,19H,13-15H2,1-2H3,(H,33,34)/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50350368
(CHEMBL1813117)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(Cl)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C28H25ClN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350375
(CHEMBL1813272)Show SMILES COc1cc(ccc1OC[C@@H]1CN(C)c2ccccc2O1)C(=O)n1c(C)c(CC(O)=O)c2ccccc12 |r| Show InChI InChI=1S/C29H28N2O6/c1-18-22(15-28(32)33)21-8-4-5-9-23(21)31(18)29(34)19-12-13-26(27(14-19)35-3)36-17-20-16-30(2)24-10-6-7-11-25(24)37-20/h4-14,20H,15-17H2,1-3H3,(H,32,33)/t20-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50350367
(CHEMBL1813116)Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)c(CC(O)=O)c3cc(C)ccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C29H28N2O5/c1-18-8-13-25-24(14-18)23(15-28(32)33)19(2)31(25)29(34)20-9-11-21(12-10-20)35-17-22-16-30(3)26-6-4-5-7-27(26)36-22/h4-14,22H,15-17H2,1-3H3,(H,32,33)/t22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Mus musculus) | BDBM50350377
(CHEMBL1813274)Show SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)n2c(C)c(CC(O)=O)c3ccccc23)Oc2ccccc12 |r| Show InChI InChI=1S/C30H30N2O5/c1-18-14-28(36-17-21-16-31(4)26-11-7-8-12-27(26)37-21)19(2)13-23(18)30(35)32-20(3)24(15-29(33)34)22-9-5-6-10-25(22)32/h5-14,21H,15-17H2,1-4H3,(H,33,34)/t21-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting |
Bioorg Med Chem 19: 4574-88 (2011)
Article DOI: 10.1016/j.bmc.2011.06.014
BindingDB Entry DOI: 10.7270/Q2FB5398 |
More data for this
Ligand-Target Pair | |
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