Compile Data Set for Download or QSAR

Found 42 hits Enz. Inhib. hit(s) with all data for entry = 50000354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004726 (1-(1-Methyl-4-pyrrolidin-1-yl-but-2-ynyl)-pyrrolid...) Show SMILES CC(C#CCN1CCCC1)N1CCCC1=O Show InChI InChI=1S/C13H20N2O/c1-12(15-11-5-7-13(15)16)6-4-10-14-8-2-3-9-14/h12H,2-3,5,7-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004734 (CHEMBL310852 | N-Methyl-N-(1-methyl-4-pyrrolidin-1...) Show SMILES CC(C#CCN1CCCC1)N(C)C(C)=O Show InChI InChI=1S/C12H20N2O/c1-11(13(3)12(2)15)7-6-10-14-8-4-5-9-14/h11H,4-5,8-10H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004665 ((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...) Show SMILES O=C1CCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004728 (1-Methyl-1-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)...) Show SMILES CC(C#CCN1CCCC1)N(C)C(N)=O Show InChI InChI=1S/C11H19N3O/c1-10(13(2)11(12)15)6-5-9-14-7-3-4-8-14/h10H,3-4,7-9H2,1-2H3,(H2,12,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004727 (1-(1-Methyl-4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CC(C#CCN1CCCC1)N1CCNC1=O Show InChI InChI=1S/C12H19N3O/c1-11(15-10-6-13-12(15)16)5-4-9-14-7-2-3-8-14/h11H,2-3,6-10H2,1H3,(H,13,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004733 (1-Methyl-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CN1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C12H19N3O/c1-13-10-11-15(12(13)16)9-5-4-8-14-6-2-3-7-14/h2-3,6-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004725 (1,3-Dimethyl-1-(1-methyl-4-pyrrolidin-1-yl-but-2-y...) Show SMILES CNC(=O)N(C)C(C)C#CCN1CCCC1 Show InChI InChI=1S/C12H21N3O/c1-11(14(3)12(16)13-2)7-6-10-15-8-4-5-9-15/h11H,4-5,8-10H2,1-3H3,(H,13,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004735 (1-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidin-2-on...) Show SMILES O=C1NCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C11H17N3O/c15-11-12-5-10-14(11)9-4-3-8-13-6-1-2-7-13/h1-2,5-10H2,(H,12,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004732 (1-Methyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-urea | C...) Show SMILES CN(CC#CCN1CCCC1)C(N)=O Show InChI InChI=1S/C10H17N3O/c1-12(10(11)14)6-2-3-7-13-8-4-5-9-13/h4-9H2,1H3,(H2,11,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004736 (1,3-Dimethyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-urea...) Show SMILES CNC(=O)N(C)CC#CCN1CCCC1 Show InChI InChI=1S/C11H19N3O/c1-12-11(15)13(2)7-3-4-8-14-9-5-6-10-14/h5-10H2,1-2H3,(H,12,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004731 (3-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidine-2,4...) Show SMILES Oc1c[nH]c(=O)n1CC#CCN1CCCC1 Show InChI InChI=1S/C11H15N3O2/c15-10-9-12-11(16)14(10)8-4-3-7-13-5-1-2-6-13/h9,15H,1-2,5-8H2,(H,12,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004730 (2-Oxo-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazolidi...) Show SMILES O=CN1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C12H17N3O2/c16-11-15-10-9-14(12(15)17)8-4-3-7-13-5-1-2-6-13/h11H,1-2,5-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004729 (1-Acetyl-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CC(=O)N1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C13H19N3O2/c1-12(17)16-11-10-15(13(16)18)9-5-4-8-14-6-2-3-7-14/h2-3,6-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004736 (1,3-Dimethyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-urea...) Show SMILES CNC(=O)N(C)CC#CCN1CCCC1 Show InChI InChI=1S/C11H19N3O/c1-12-11(15)13(2)7-3-4-8-14-9-5-6-10-14/h5-10H2,1-2H3,(H,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004726 (1-(1-Methyl-4-pyrrolidin-1-yl-but-2-ynyl)-pyrrolid...) Show SMILES CC(C#CCN1CCCC1)N1CCCC1=O Show InChI InChI=1S/C13H20N2O/c1-12(15-11-5-7-13(15)16)6-4-10-14-8-2-3-9-14/h12H,2-3,5,7-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004728 (1-Methyl-1-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)...) Show SMILES CC(C#CCN1CCCC1)N(C)C(N)=O Show InChI InChI=1S/C11H19N3O/c1-10(13(2)11(12)15)6-5-9-14-7-3-4-8-14/h10H,3-4,7-9H2,1-2H3,(H2,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004736 (1,3-Dimethyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-urea...) Show SMILES CNC(=O)N(C)CC#CCN1CCCC1 Show InChI InChI=1S/C11H19N3O/c1-12-11(15)13(2)7-3-4-8-14-9-5-6-10-14/h5-10H2,1-2H3,(H,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004731 (3-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidine-2,4...) Show SMILES Oc1c[nH]c(=O)n1CC#CCN1CCCC1 Show InChI InChI=1S/C11H15N3O2/c15-10-9-12-11(16)14(10)8-4-3-7-13-5-1-2-6-13/h9,15H,1-2,5-8H2,(H,12,16)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004732 (1-Methyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-urea | C...) Show SMILES CN(CC#CCN1CCCC1)C(N)=O Show InChI InChI=1S/C10H17N3O/c1-12(10(11)14)6-2-3-7-13-8-4-5-9-13/h4-9H2,1H3,(H2,11,14)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004737 (3-Methyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-pyrrolid...) Show SMILES CC1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C13H20N2O/c1-12-6-11-15(13(12)16)10-5-4-9-14-7-2-3-8-14/h12H,2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004727 (1-(1-Methyl-4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CC(C#CCN1CCCC1)N1CCNC1=O Show InChI InChI=1S/C12H19N3O/c1-11(15-10-6-13-12(15)16)5-4-9-14-7-2-3-8-14/h11H,2-3,6-10H2,1H3,(H,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004730 (2-Oxo-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazolidi...) Show SMILES O=CN1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C12H17N3O2/c16-11-15-10-9-14(12(15)17)8-4-3-7-13-5-1-2-6-13/h11H,1-2,5-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004735 (1-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidin-2-on...) Show SMILES O=C1NCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C11H17N3O/c15-11-12-5-10-14(11)9-4-3-8-13-6-1-2-7-13/h1-2,5-10H2,(H,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004734 (CHEMBL310852 | N-Methyl-N-(1-methyl-4-pyrrolidin-1...) Show SMILES CC(C#CCN1CCCC1)N(C)C(C)=O Show InChI InChI=1S/C12H20N2O/c1-11(13(3)12(2)15)7-6-10-14-8-4-5-9-14/h11H,4-5,8-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004733 (1-Methyl-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CN1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C12H19N3O/c1-13-10-11-15(12(13)16)9-5-4-8-14-6-2-3-7-14/h2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004725 (1,3-Dimethyl-1-(1-methyl-4-pyrrolidin-1-yl-but-2-y...) Show SMILES CNC(=O)N(C)C(C)C#CCN1CCCC1 Show InChI InChI=1S/C12H21N3O/c1-11(14(3)12(16)13-2)7-6-10-15-8-4-5-9-15/h11H,4-5,8-10H2,1-3H3,(H,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004665 ((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...) Show SMILES O=C1CCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004735 (1-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidin-2-on...) Show SMILES O=C1NCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C11H17N3O/c15-11-12-5-10-14(11)9-4-3-8-13-6-1-2-7-13/h1-2,5-10H2,(H,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004726 (1-(1-Methyl-4-pyrrolidin-1-yl-but-2-ynyl)-pyrrolid...) Show SMILES CC(C#CCN1CCCC1)N1CCCC1=O Show InChI InChI=1S/C13H20N2O/c1-12(15-11-5-7-13(15)16)6-4-10-14-8-2-3-9-14/h12H,2-3,5,7-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004727 (1-(1-Methyl-4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CC(C#CCN1CCCC1)N1CCNC1=O Show InChI InChI=1S/C12H19N3O/c1-11(15-10-6-13-12(15)16)5-4-9-14-7-2-3-8-14/h11H,2-3,6-10H2,1H3,(H,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004734 (CHEMBL310852 | N-Methyl-N-(1-methyl-4-pyrrolidin-1...) Show SMILES CC(C#CCN1CCCC1)N(C)C(C)=O Show InChI InChI=1S/C12H20N2O/c1-11(13(3)12(2)15)7-6-10-14-8-4-5-9-14/h11H,4-5,8-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004732 (1-Methyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-urea | C...) Show SMILES CN(CC#CCN1CCCC1)C(N)=O Show InChI InChI=1S/C10H17N3O/c1-12(10(11)14)6-2-3-7-13-8-4-5-9-13/h4-9H2,1H3,(H2,11,14)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.49E+4	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004731 (3-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidine-2,4...) Show SMILES Oc1c[nH]c(=O)n1CC#CCN1CCCC1 Show InChI InChI=1S/C11H15N3O2/c15-10-9-12-11(16)14(10)8-4-3-7-13-5-1-2-6-13/h9,15H,1-2,5-8H2,(H,12,16)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.64E+4	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004729 (1-Acetyl-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CC(=O)N1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C13H19N3O2/c1-12(17)16-11-10-15(13(16)18)9-5-4-8-14-6-2-3-7-14/h2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004665 ((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...) Show SMILES O=C1CCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004730 (2-Oxo-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazolidi...) Show SMILES O=CN1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C12H17N3O2/c16-11-15-10-9-14(12(15)17)8-4-3-7-13-5-1-2-6-13/h11H,1-2,5-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004737 (3-Methyl-1-(4-pyrrolidin-1-yl-but-2-ynyl)-pyrrolid...) Show SMILES CC1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C13H20N2O/c1-12-6-11-15(13(12)16)10-5-4-9-14-7-2-3-8-14/h12H,2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004733 (1-Methyl-3-(4-pyrrolidin-1-yl-but-2-ynyl)-imidazol...) Show SMILES CN1CCN(CC#CCN2CCCC2)C1=O Show InChI InChI=1S/C12H19N3O/c1-13-10-11-15(12(13)16)9-5-4-8-14-6-2-3-7-14/h2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004725 (1,3-Dimethyl-1-(1-methyl-4-pyrrolidin-1-yl-but-2-y...) Show SMILES CNC(=O)N(C)C(C)C#CCN1CCCC1 Show InChI InChI=1S/C12H21N3O/c1-11(14(3)12(16)13-2)7-6-10-15-8-4-5-9-15/h11H,4-5,8-10H2,1-3H3,(H,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Muscarinic acetylcholine receptor M3 agonistic/antagonistic activity in guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50004728 (1-Methyl-1-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)...) Show SMILES CC(C#CCN1CCCC1)N(C)C(N)=O Show InChI InChI=1S/C11H19N3O/c1-10(13(2)11(12)15)6-5-9-14-7-3-4-8-14/h10H,3-4,7-9H2,1-2H3,(H2,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Dissociation constant for complex with muscarinic acetylcholine receptor M3 of guinea pig ileum				J Med Chem 35: 3270-9 (1992) BindingDB Entry DOI: 10.7270/Q2KP813K
					More data for this Ligand-Target Pair