BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50034052
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [3H]BMS-725519 from human CB1 receptor expressed in CHO cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [3H]BMS-725519 from rat brain CB1 receptor after 90 mins by scintillation counting				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50356013 (CHEMBL1911374 \| CHEMBL1911375) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [3H]BMS-725519 from rat brain CB1 receptor after 90 mins by scintillation counting				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50356013 (CHEMBL1911374 \| CHEMBL1911375) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [3H]-SR-141716 from human CB1 receptor				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50356013 (CHEMBL1911374 \| CHEMBL1911375) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	12.4	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [3H]-SR-141716 from rat CB1 receptor				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50356013 (CHEMBL1911374 \| CHEMBL1911375) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	29.1	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Binding affinity to rat brain CB1 receptor after 90 mins by scintillation counting				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50356013 (CHEMBL1911374 \| CHEMBL1911375) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human CB2 receptor				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50356013 (CHEMBL1911374 \| CHEMBL1911375) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.95	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Binding affinity to human CB1 receptor expressed in CHO cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 21: 6856-60 (2011) Article DOI: 10.1016/j.bmcl.2011.09.016 BindingDB Entry DOI: 10.7270/Q2WS8TN3
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair