Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with all data for entry = 50034118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357377 (CHEMBL1917268) Show SMILES Cc1ccccc1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C18H16N2O3S/c1-12-4-2-3-5-14(12)11-24-18-20-19-17(23-18)13-6-7-15-16(10-13)22-9-8-21-15/h2-7,10H,8-9,11H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357380 (CHEMBL1917271) Show SMILES Brc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C17H13BrN2O3S/c18-13-4-1-11(2-5-13)10-24-17-20-19-16(23-17)12-3-6-14-15(9-12)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357385 (CHEMBL1917276) Show SMILES Ic1ccccc1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H13IN2O3S/c18-13-4-2-1-3-12(13)10-24-17-20-19-16(23-17)11-5-6-14-15(9-11)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357378 (CHEMBL1917269) Show SMILES Brc1ccccc1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H13BrN2O3S/c18-13-4-2-1-3-12(13)10-24-17-20-19-16(23-17)11-5-6-14-15(9-11)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357382 (CHEMBL1917273) Show SMILES Clc1cccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C17H13ClN2O3S/c18-13-3-1-2-11(8-13)10-24-17-20-19-16(23-17)12-4-5-14-15(9-12)22-7-6-21-14/h1-5,8-9H,6-7,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357384 (CHEMBL1917275) Show SMILES Fc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)c(F)c1 Show InChI InChI=1S/C17H12F2N2O3S/c18-12-3-1-11(13(19)8-12)9-25-17-21-20-16(24-17)10-2-4-14-15(7-10)23-6-5-22-14/h1-4,7-8H,5-6,9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357379 (CHEMBL1917270) Show SMILES Brc1cccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C17H13BrN2O3S/c18-13-3-1-2-11(8-13)10-24-17-20-19-16(23-17)12-4-5-14-15(9-12)22-7-6-21-14/h1-5,8-9H,6-7,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357369 (CHEMBL1917260) Show SMILES [O-][N+](=O)c1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C17H13N3O5S/c21-20(22)13-4-1-11(2-5-13)10-26-17-19-18-16(25-17)12-3-6-14-15(9-12)24-8-7-23-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357375 (CHEMBL1917266) Show SMILES Clc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C17H13ClN2O3S/c18-13-4-1-11(2-5-13)10-24-17-20-19-16(23-17)12-3-6-14-15(9-12)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357370 (CHEMBL1917261) Show SMILES Fc1ccccc1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H13FN2O3S/c18-13-4-2-1-3-12(13)10-24-17-20-19-16(23-17)11-5-6-14-15(9-11)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357368 (CHEMBL1917259) Show SMILES Cc1cccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C18H16N2O3S/c1-12-3-2-4-13(9-12)11-24-18-20-19-17(23-18)14-5-6-15-16(10-14)22-8-7-21-15/h2-6,9-10H,7-8,11H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357376 (CHEMBL1917267) Show SMILES Ic1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C17H13IN2O3S/c18-13-4-1-11(2-5-13)10-24-17-20-19-16(23-17)12-3-6-14-15(9-12)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357373 (CHEMBL1917264) Show SMILES Fc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C17H13FN2O3S/c18-13-4-1-11(2-5-13)10-24-17-20-19-16(23-17)12-3-6-14-15(9-12)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357374 (CHEMBL1917265) Show SMILES [O-][N+](=O)c1cccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C17H13N3O5S/c21-20(22)13-3-1-2-11(8-13)10-26-17-19-18-16(25-17)12-4-5-14-15(9-12)24-7-6-23-14/h1-5,8-9H,6-7,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357372 (CHEMBL1917263) Show SMILES Cc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C18H16N2O3S/c1-12-2-4-13(5-3-12)11-24-18-20-19-17(23-18)14-6-7-15-16(10-14)22-9-8-21-15/h2-7,10H,8-9,11H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357381 (CHEMBL1917272) Show SMILES Clc1ccccc1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H13ClN2O3S/c18-13-4-2-1-3-12(13)10-24-17-20-19-16(23-17)11-5-6-14-15(9-11)22-8-7-21-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357367 (CHEMBL1917258) Show SMILES C(Sc1nnc(o1)-c1ccc2OCCOc2c1)c1ccccc1 Show InChI InChI=1S/C17H14N2O3S/c1-2-4-12(5-3-1)11-23-17-19-18-16(22-17)13-6-7-14-15(10-13)21-9-8-20-14/h1-7,10H,8-9,11H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357371 (CHEMBL1917262) Show SMILES [O-][N+](=O)c1ccccc1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H13N3O5S/c21-20(22)13-4-2-1-3-12(13)10-26-17-19-18-16(25-17)11-5-6-14-15(9-11)24-8-7-23-14/h1-6,9H,7-8,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50357383 (CHEMBL1917274) Show SMILES Fc1cccc(F)c1CSc1nnc(o1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H12F2N2O3S/c18-12-2-1-3-13(19)11(12)9-25-17-21-20-16(24-17)10-4-5-14-15(8-10)23-7-6-22-14/h1-5,8H,6-7,9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay				Bioorg Med Chem 19: 6518-24 (2011) Article DOI: 10.1016/j.bmc.2011.08.013 BindingDB Entry DOI: 10.7270/Q2H70G7M
					More data for this Ligand-Target Pair