BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50034164
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50358130 (CHEMBL1923808) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC1 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC1 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50358130 (CHEMBL1923808) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC2 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC2 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 3 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	21.8	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC3 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50358130 (CHEMBL1923808) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(F)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	23.9	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC3 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50358130 (CHEMBL1923808) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50.2	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC6 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	57.3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length HDAC6 using fluorophore conjugated substrate by fluorescence assay				J Med Chem 54: 5576-82 (2011) Article DOI: 10.1021/jm200620f BindingDB Entry DOI: 10.7270/Q2JW8F90
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair