Compile Data Set for Download or QSAR

Found 13 hits Enz. Inhib. hit(s) with all data for entry = 50034201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358788 (CHEMBL1922756) Show SMILES FC(F)(F)c1ccc(OCC(=O)c2ccc(Cl)nc2)cc1 Show InChI InChI=1S/C14H9ClF3NO2/c15-13-6-1-9(7-19-13)12(20)8-21-11-4-2-10(3-5-11)14(16,17)18/h1-7H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358787 (CHEMBL1922750) Show SMILES Clc1ccc(cn1)C(=O)COc1cccc(Br)c1 Show InChI InChI=1S/C13H9BrClNO2/c14-10-2-1-3-11(6-10)18-8-12(17)9-4-5-13(15)16-7-9/h1-7H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358780 (CHEMBL1922760) Show SMILES Clc1ccc(cn1)C(=O)COc1ccccc1-c1ccccn1 Show InChI InChI=1S/C18H13ClN2O2/c19-18-9-8-13(11-21-18)16(22)12-23-17-7-2-1-5-14(17)15-6-3-4-10-20-15/h1-11H,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358785 (CHEMBL1922728) Show SMILES Clc1ccc(cn1)C(=O)COc1ccccc1Br Show InChI InChI=1S/C13H9BrClNO2/c14-10-3-1-2-4-12(10)18-8-11(17)9-5-6-13(15)16-7-9/h1-7H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358786 (CHEMBL1922742) Show SMILES Brc1ccccc1OCC(=O)c1ccc(NCCc2cccnc2)nc1 Show InChI InChI=1S/C20H18BrN3O2/c21-17-5-1-2-6-19(17)26-14-18(25)16-7-8-20(24-13-16)23-11-9-15-4-3-10-22-12-15/h1-8,10,12-13H,9,11,14H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358781 (CHEMBL1922765) Show SMILES Clc1ccc(cn1)C(=O)COc1ccccc1-c1cncnc1 Show InChI InChI=1S/C17H12ClN3O2/c18-17-6-5-12(9-21-17)15(22)10-23-16-4-2-1-3-14(16)13-7-19-11-20-8-13/h1-9,11H,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358782 (CHEMBL1922768) Show SMILES Cn1cc(cn1)-c1ccccc1OCC(=O)c1ccc(Cl)nc1 Show InChI InChI=1S/C17H14ClN3O2/c1-21-10-13(9-20-21)14-4-2-3-5-16(14)23-11-15(22)12-6-7-17(18)19-8-12/h2-10H,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358779 (CHEMBL1922759) Show SMILES Clc1ccc(cn1)C(=O)COc1ccccc1-c1ccccc1 Show InChI InChI=1S/C19H14ClNO2/c20-19-11-10-15(12-21-19)17(22)13-23-18-9-5-4-8-16(18)14-6-2-1-3-7-14/h1-12H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as inhibition of EC80 glutamate-induced calcium mobili...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50358783 (CHEMBL1346011) Show SMILES Oc1ccc(C(=O)COc2ccccc2Br)c(O)c1 Show InChI InChI=1S/C14H11BrO4/c15-11-3-1-2-4-14(11)19-8-13(18)10-6-5-9(16)7-12(10)17/h1-7,16-17H,8H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic acetylcholine receptor 1 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of acetylcholine-in...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50358783 (CHEMBL1346011) Show SMILES Oc1ccc(C(=O)COc2ccccc2Br)c(O)c1 Show InChI InChI=1S/C14H11BrO4/c15-11-3-1-2-4-14(11)19-8-13(18)10-6-5-9(16)7-12(10)17/h1-7,16-17H,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic acetylcholine receptor 4 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of acetylcholine-in...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358784 (CHEMBL1922727) Show SMILES Brc1ccccc1OCC(=O)c1ccccn1 Show InChI InChI=1S/C13H10BrNO2/c14-10-5-1-2-7-13(10)17-9-12(16)11-6-3-4-8-15-11/h1-8H,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as potentiation of EC20 glutamate-induced c...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50358783 (CHEMBL1346011) Show SMILES Oc1ccc(C(=O)COc2ccccc2Br)c(O)c1 Show InChI InChI=1S/C14H11BrO4/c15-11-3-1-2-4-14(11)19-8-13(18)10-6-5-9(16)7-12(10)17/h1-7,16-17H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as potentiation of EC20 glutamate-induced c...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50358783 (CHEMBL1346011) Show SMILES Oc1ccc(C(=O)COc2ccccc2Br)c(O)c1 Show InChI InChI=1S/C14H11BrO4/c15-11-3-1-2-4-14(11)19-8-13(18)10-6-5-9(16)7-12(10)17/h1-7,16-17H,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu4 receptor expressed in human HEK293 cells co-expressing GIRK potassium channels assessed as potentiation o...				Bioorg Med Chem Lett 21: 6955-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.131 BindingDB Entry DOI: 10.7270/Q2S75GRQ
					More data for this Ligand-Target Pair