BindingDB PrimarySearch

Found 25 hits Enz. Inhib. hit(s) with all data for entry = 50034613
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CFMS kinase catalytic domain using biotin-EAIYAPFAKKK-NH2 as substrate after 40 mins by NXT scintillation ...				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged B-RAF after 60 mins by fluorescence polarization assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged ERK2 after 60 mins by fluorescence polarization assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of mouse LCK				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human PDGFR-1b				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged MK2 using K(biotin)KLNRTLSVA as substrate after 2 hrs by scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human cKIT catalytic domain after by scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human PKCa catalytic domain after by scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human JAK2 catalytic domain after by scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human PKCb1 catalytic domain after by scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human FLT3 catalytic domain after by scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human ITK				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human SYK				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human JNK3				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GST-tagged c-SRC autophosphorylation using biotin-(6-amino caproic acid)-AAAQQIYGQ-NH2 as substrate after 40 mins by homogenous t...				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CDK4 catalytic domain after 30 mins by liquid scintillation counting				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GST-tagged VEGFR2 catalytic domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 40 mins by homogenous time-resol...				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GST-tagged Tie2 using biotin-(6-amino caproic acid)-LEARLVAYEGWVAGKKK-NH2 after 2 hrs by homogenous time-resolved fluorescence me...				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged ERBB2 using biotin-amino hexanoic acid-RAHEEIYHFFFAKKK-NH2 as substrate after 15 mins by scintillation proximity assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged ERBB4 using biotin-amino hexanoic acid-RAHEEIYHFFFAKKK-NH2 as substrate after 15 mins by scintillation proximity assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GST-tagged PLK1 using biotin-amino hexanoic acid-SFNDTLDFD-NH2 as substrate after 15 mins by scintillation proximity assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C zeta type (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged PKCz using biotin-(amino hexanoic acid)-FKLKRKGSFKKFA-CONH2 as substrate after 40 mins by scintillation proximity assa...				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged EGFR using biotin-amino hexanoic acid-RAHEEIYHFFFAKKK-NH2 as substrate after 15 mins by scintillation proximity assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged PDHK4 using biotin-YHGHSMSDPGVSYRRR-amide as substrate after 20 mins by scintillation proximity assay				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM32362 (5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...) Show SMILES COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human His-tagged GSK-3b using biotin-6-amino caproic acid-AAAKRREILSRRPS(PO3)YR-amide as substrate after 19 mins by NXT scintillation c...				Proc Natl Acad Sci U S A 102: 16078-83 (2005) Article DOI: 10.1073/pnas.0502000102 BindingDB Entry DOI: 10.7270/Q2PC32TB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair