Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tissue factor (Homo sapiens (Human)) | BDBM50235149 (CHEMBL4066780) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0280 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235153 (CHEBI:67985 | CHEMBL510111) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0350 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235152 (CHEBI:4747 | CHEMBL230128) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0540 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235142 (CHEMBL4070749) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0780 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235147 (Vitalboside A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0950 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50442880 (4-Epi-Hederagenin | Hederagenin | US11660306, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.221 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50234590 (CHEMBL4092579) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.221 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50346613 (CHEMBL470029 | Oleanonic Acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.221 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235150 (CHEBI:67947 | CHEMBL1910843) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235151 (CHEMBL4064877) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235148 (CHEMBL4062123) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.801 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235154 (CHEMBL4080417) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50246619 ((4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-benzyl 10-hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50346601 (NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235146 (CHEMBL4096910) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235144 (CHEMBL3343908) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235143 (CHEMBL2386940) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50140172 (CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue factor (Homo sapiens (Human)) | BDBM50235145 (CHEMBL3343919) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs... | Bioorg Med Chem Lett 27: 1026-1030 (2017) Article DOI: 10.1016/j.bmcl.2016.12.066 BindingDB Entry DOI: 10.7270/Q2B27XJD | |||||||||||
More data for this Ligand-Target Pair |