Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50034910 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor
(MOUSE) | BDBM50290872
((-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a...)Show SMILES CN1CC[C@@]2(Cc3nc4ccccc4cc3C[C@H]2C1)c1cccc(O)c1 |r| Show InChI InChI=1S/C23H24N2O/c1-25-10-9-23(18-6-4-7-20(26)13-18)14-22-17(12-19(23)15-25)11-16-5-2-3-8-21(16)24-22/h2-8,11,13,19,26H,9-10,12,14-15H2,1H3/t19-,23+/m0/s1 | PDB
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| Article
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50450528
(CHEMBL2051964)Show SMILES Cc1ccc(O)c(c1)C(=O)NC[C@]1(C)C[C@H](O)CC(C)(C)C1 |r| Show InChI InChI=1S/C18H27NO3/c1-12-5-6-15(21)14(7-12)16(22)19-11-18(4)9-13(20)8-17(2,3)10-18/h5-7,13,20-21H,8-11H2,1-4H3,(H,19,22)/t13-,18-/m1/s1 | PDB
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| Article
| 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
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| 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50290869
((4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=S)c1[nH]c2C[C@H]3CN(CC)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3OS/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-21-17(4)23(24(30)28(6-2)7-3)26-22(21)14-19(25)16-27/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
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| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
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| Article
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
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| Article
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50061063
((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(C)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C24H33N3O2/c1-5-27(6-2)23(29)22-16(3)20-13-18-15-26(4)11-10-24(18,14-21(20)25-22)17-8-7-9-19(28)12-17/h7-9,12,18,25,28H,5-6,10-11,13-15H2,1-4H3/t18-,24+/m0/s1 | PDB
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| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50290866
((4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCOC(=O)c1[nH]c2C[C@H]3CN(CC)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C23H30N2O3/c1-4-25-10-9-23(16-7-6-8-18(26)11-16)13-19-15(3)21(22(27)28-5-2)24-20(19)12-17(23)14-25/h6-8,11,17,24,26H,4-5,9-10,12-14H2,1-3H3/t17-,23+/m0/s1 | PDB
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| Article
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50290868
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(=O)N(C(C)C)C(C)C)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C27H39N3O2/c1-7-29-12-11-27(20-9-8-10-22(31)13-20)15-24-23(14-21(27)16-29)19(6)25(28-24)26(32)30(17(2)3)18(4)5/h8-10,13,17-18,21,28,31H,7,11-12,14-16H2,1-6H3/t21-,27+/m0/s1 | PDB
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| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50290870
((4aR,8aR)-4a-(3-Hydroxy-phenyl)-3,7-dimethyl-4,4a,...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@H]3CN(C)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C24H33N3O2/c1-5-27(6-2)23(29)22-16(3)20-14-24(17-8-7-9-19(28)12-17)10-11-26(4)15-18(24)13-21(20)25-22/h7-9,12,18,25,28H,5-6,10-11,13-15H2,1-4H3/t18-,24+/m0/s1 | PDB
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| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50290871
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(=O)N(C)C)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C23H31N3O2/c1-5-26-10-9-23(16-7-6-8-18(27)11-16)13-20-19(12-17(23)14-26)15(2)21(24-20)22(28)25(3)4/h6-8,11,17,24,27H,5,9-10,12-14H2,1-4H3/t17-,23+/m0/s1 | PDB
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| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50450528
(CHEMBL2051964)Show SMILES Cc1ccc(O)c(c1)C(=O)NC[C@]1(C)C[C@H](O)CC(C)(C)C1 |r| Show InChI InChI=1S/C18H27NO3/c1-12-5-6-15(21)14(7-12)16(22)19-11-18(4)9-13(20)8-17(2,3)10-18/h5-7,13,20-21H,8-11H2,1-4H3,(H,19,22)/t13-,18-/m1/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50290867
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(N)=O)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C21H27N3O2/c1-3-24-8-7-21(14-5-4-6-16(25)9-14)11-18-17(10-15(21)12-24)13(2)19(23-18)20(22)26/h4-6,9,15,23,25H,3,7-8,10-12H2,1-2H3,(H2,22,26)/t15-,21+/m0/s1 | PDB
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| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50450528
(CHEMBL2051964)Show SMILES Cc1ccc(O)c(c1)C(=O)NC[C@]1(C)C[C@H](O)CC(C)(C)C1 |r| Show InChI InChI=1S/C18H27NO3/c1-12-5-6-15(21)14(7-12)16(22)19-11-18(4)9-13(20)8-17(2,3)10-18/h5-7,13,20-21H,8-11H2,1-4H3,(H,19,22)/t13-,18-/m1/s1 | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290869
((4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=S)c1[nH]c2C[C@H]3CN(CC)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3OS/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-21-17(4)23(24(30)28(6-2)7-3)26-22(21)14-19(25)16-27/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
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| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290868
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(=O)N(C(C)C)C(C)C)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C27H39N3O2/c1-7-29-12-11-27(20-9-8-10-22(31)13-20)15-24-23(14-21(27)16-29)19(6)25(28-24)26(32)30(17(2)3)18(4)5/h8-10,13,17-18,21,28,31H,7,11-12,14-16H2,1-6H3/t21-,27+/m0/s1 | PDB
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| 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290872
((-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a...)Show SMILES CN1CC[C@@]2(Cc3nc4ccccc4cc3C[C@H]2C1)c1cccc(O)c1 |r| Show InChI InChI=1S/C23H24N2O/c1-25-10-9-23(18-6-4-7-20(26)13-18)14-22-17(12-19(23)15-25)11-16-5-2-3-8-21(16)24-22/h2-8,11,13,19,26H,9-10,12,14-15H2,1H3/t19-,23+/m0/s1 | PDB
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CHEMBL
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UniChem
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| Article
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290867
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(N)=O)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C21H27N3O2/c1-3-24-8-7-21(14-5-4-6-16(25)9-14)11-18-17(10-15(21)12-24)13(2)19(23-18)20(22)26/h4-6,9,15,23,25H,3,7-8,10-12H2,1-2H3,(H2,22,26)/t15-,21+/m0/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290870
((4aR,8aR)-4a-(3-Hydroxy-phenyl)-3,7-dimethyl-4,4a,...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@H]3CN(C)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C24H33N3O2/c1-5-27(6-2)23(29)22-16(3)20-14-24(17-8-7-9-19(28)12-17)10-11-26(4)15-18(24)13-21(20)25-22/h7-9,12,18,25,28H,5-6,10-11,13-15H2,1-4H3/t18-,24+/m0/s1 | PDB
Reactome pathway
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PC sid
UniChem
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| Article
| 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50061063
((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(C)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C24H33N3O2/c1-5-27(6-2)23(29)22-16(3)20-13-18-15-26(4)11-10-24(18,14-21(20)25-22)17-8-7-9-19(28)12-17/h7-9,12,18,25,28H,5-6,10-11,13-15H2,1-4H3/t18-,24+/m0/s1 | PDB
Reactome pathway
KEGG
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UniChem
Similars
| Article
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290867
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(N)=O)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C21H27N3O2/c1-3-24-8-7-21(14-5-4-6-16(25)9-14)11-18-17(10-15(21)12-24)13(2)19(23-18)20(22)26/h4-6,9,15,23,25H,3,7-8,10-12H2,1-2H3,(H2,22,26)/t15-,21+/m0/s1 | PDB
Reactome pathway
KEGG
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UniChem
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| Article
| 139 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290866
((4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCOC(=O)c1[nH]c2C[C@H]3CN(CC)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C23H30N2O3/c1-4-25-10-9-23(16-7-6-8-18(26)11-16)13-19-15(3)21(22(27)28-5-2)24-20(19)12-17(23)14-25/h6-8,11,17,24,26H,4-5,9-10,12-14H2,1-3H3/t17-,23+/m0/s1 | PDB
Reactome pathway
KEGG
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PC sid
UniChem
| Article
| 141 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290866
((4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCOC(=O)c1[nH]c2C[C@H]3CN(CC)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C23H30N2O3/c1-4-25-10-9-23(16-7-6-8-18(26)11-16)13-19-15(3)21(22(27)28-5-2)24-20(19)12-17(23)14-25/h6-8,11,17,24,26H,4-5,9-10,12-14H2,1-3H3/t17-,23+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
| Article
| 169 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290872
((-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a...)Show SMILES CN1CC[C@@]2(Cc3nc4ccccc4cc3C[C@H]2C1)c1cccc(O)c1 |r| Show InChI InChI=1S/C23H24N2O/c1-25-10-9-23(18-6-4-7-20(26)13-18)14-22-17(12-19(23)15-25)11-16-5-2-3-8-21(16)24-22/h2-8,11,13,19,26H,9-10,12,14-15H2,1H3/t19-,23+/m0/s1 | PDB
UniProtKB/SwissProt
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| Purchase
CHEMBL
MCE
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UniChem
Patents
Similars
| Article
| 312 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
Patents
Similars
| Article
| 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Patents
Similars
| Article
| 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290869
((4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=S)c1[nH]c2C[C@H]3CN(CC)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3OS/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-21-17(4)23(24(30)28(6-2)7-3)26-22(21)14-19(25)16-27/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 449 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50061063
((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(C)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C24H33N3O2/c1-5-27(6-2)23(29)22-16(3)20-13-18-15-26(4)11-10-24(18,14-21(20)25-22)17-8-7-9-19(28)12-17/h7-9,12,18,25,28H,5-6,10-11,13-15H2,1-4H3/t18-,24+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50290871
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(=O)N(C)C)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C23H31N3O2/c1-5-26-10-9-23(16-7-6-8-18(27)11-16)13-20-19(12-17(23)14-26)15(2)21(24-20)22(28)25(3)4/h6-8,11,17,24,27H,5,9-10,12-14H2,1-4H3/t17-,23+/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Patents
Similars
| Article
| 580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290871
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(=O)N(C)C)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C23H31N3O2/c1-5-26-10-9-23(16-7-6-8-18(27)11-16)13-20-19(12-17(23)14-26)15(2)21(24-20)22(28)25(3)4/h6-8,11,17,24,27H,5,9-10,12-14H2,1-4H3/t17-,23+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290870
((4aR,8aR)-4a-(3-Hydroxy-phenyl)-3,7-dimethyl-4,4a,...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@H]3CN(C)CC[C@@]3(Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C24H33N3O2/c1-5-27(6-2)23(29)22-16(3)20-14-24(17-8-7-9-19(28)12-17)10-11-26(4)15-18(24)13-21(20)25-22/h7-9,12,18,25,28H,5-6,10-11,13-15H2,1-4H3/t18-,24+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50290868
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN1CC[C@@]2(Cc3[nH]c(C(=O)N(C(C)C)C(C)C)c(C)c3C[C@H]2C1)c1cccc(O)c1 Show InChI InChI=1S/C27H39N3O2/c1-7-29-12-11-27(20-9-8-10-22(31)13-20)15-24-23(14-21(27)16-29)19(6)25(28-24)26(32)30(17(2)3)18(4)5/h8-10,13,17-18,21,28,31H,7,11-12,14-16H2,1-6H3/t21-,27+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50061061
((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)Show SMILES CCN(CC)C(=O)c1[nH]c2C[C@]3(CCN(CC)C[C@@H]3Cc2c1C)c1cccc(O)c1 Show InChI InChI=1S/C25H35N3O2/c1-5-27-12-11-25(18-9-8-10-20(29)13-18)15-22-21(14-19(25)16-27)17(4)23(26-22)24(30)28(6-2)7-3/h8-10,13,19,26,29H,5-7,11-12,14-16H2,1-4H3/t19-,25+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates |
Bioorg Med Chem Lett 7: 2967-2972 (1997)
Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD |
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Ligand-Target Pair | |
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