Compile Data Set for Download or QSAR

Found 66 hits Enz. Inhib. hit(s) with all data for entry = 50049277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237925 (CHEMBL4103223) Show SMILES COc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C18H13NO6S/c1-11-15-8-5-13(9-17(15)24-18(20)16(11)10-19)25-26(21,22)14-6-3-12(23-2)4-7-14/h3-9H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237961 (CHEMBL4060753) Show SMILES CCCCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C15H15NO5S/c1-3-4-7-22(18,19)21-11-5-6-12-10(2)13(9-16)15(17)20-14(12)8-11/h5-6,8H,3-4,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237964 (CHEMBL4090465) Show SMILES CCCCCCCCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C19H23NO5S/c1-3-4-5-6-7-8-11-26(22,23)25-15-9-10-16-14(2)17(13-20)19(21)24-18(16)12-15/h9-10,12H,3-8,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237931 (CHEMBL4095459) Show SMILES CCCCCCCCS(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1OS(=O)(=O)CCCCCCCC Show InChI InChI=1S/C26H40O8S2/c1-4-6-8-10-12-14-18-35(28,29)33-23-17-16-22-21(3)20-24(27)32-25(22)26(23)34-36(30,31)19-15-13-11-9-7-5-2/h16-17,20H,4-15,18-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237942 (CHEMBL4078955) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccccc3[N+]([O-])=O)ccc12 Show InChI InChI=1S/C17H10N2O7S/c1-10-12-7-6-11(8-15(12)25-17(20)13(10)9-18)26-27(23,24)16-5-3-2-4-14(16)19(21)22/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 44-53 nM				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237915 (CHEMBL4069435) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C17H10N2O7S/c1-10-14-7-4-12(8-16(14)25-17(20)15(10)9-18)26-27(23,24)13-5-2-11(3-6-13)19(21)22/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237939 (CHEMBL4077330) Show SMILES Cc1cc(=O)oc2c(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)c(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C22H14N2O12S2/c1-13-12-20(25)34-21-18(13)10-11-19(35-37(30,31)16-6-2-14(3-7-16)23(26)27)22(21)36-38(32,33)17-8-4-15(5-9-17)24(28)29/h2-12H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237962 (CHEMBL4079164) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(=O)(=O)c3ccccc3[N+]([O-])=O)ccc12 Show InChI InChI=1S/C16H10ClNO7S/c1-9-11-7-6-10(8-13(11)24-16(19)15(9)17)25-26(22,23)14-5-3-2-4-12(14)18(20)21/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237920 (CHEMBL4087225) Show SMILES Cc1cc(=O)oc2c(OS(=O)(=O)c3cc(Cl)ccc3Cl)c(OS(=O)(=O)c3cc(Cl)ccc3Cl)ccc12 Show InChI InChI=1S/C22H12Cl4O8S2/c1-11-8-20(27)32-21-14(11)4-7-17(33-35(28,29)18-9-12(23)2-5-15(18)25)22(21)34-36(30,31)19-10-13(24)3-6-16(19)26/h2-10H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237915 (CHEMBL4069435) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C17H10N2O7S/c1-10-14-7-4-12(8-16(14)25-17(20)15(10)9-18)26-27(23,24)13-5-2-11(3-6-13)19(21)22/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Effect on functional cellular GR-antagonism (GRAF) in human Glucocorticoid receptor (GR) expressing cells				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237946 (CHEMBL4105082) Show SMILES Cc1cc(=O)oc2cc(OS(=O)(=O)c3cc(Cl)c(Cl)cc3Cl)ccc12 Show InChI InChI=1S/C16H9Cl3O5S/c1-8-4-16(20)23-14-5-9(2-3-10(8)14)24-25(21,22)15-7-12(18)11(17)6-13(15)19/h2-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR)				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237965 (CHEMBL4068298) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)c(c3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C16H9Cl2NO7S/c1-8-11-4-2-9(6-14(11)25-16(20)15(8)18)26-27(23,24)10-3-5-12(17)13(7-10)19(21)22/h2-7H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237928 (CHEMBL4084312) Show SMILES CCCCS(=O)(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 Show InChI InChI=1S/C14H15ClO5S/c1-3-4-7-21(17,18)20-10-5-6-11-9(2)13(15)14(16)19-12(11)8-10/h5-6,8H,3-4,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237916 (CHEMBL4094534) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(=O)(=O)c3cc(Cl)ccc3Cl)ccc12 Show InChI InChI=1S/C16H9Cl3O5S/c1-8-11-4-3-10(7-13(11)23-16(20)15(8)19)24-25(21,22)14-6-9(17)2-5-12(14)18/h2-7H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237923 (CHEMBL4075025) Show SMILES CCS(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1OS(=O)(=O)CC Show InChI InChI=1S/C14H16O8S2/c1-4-23(16,17)21-11-7-6-10-9(3)8-12(15)20-13(10)14(11)22-24(18,19)5-2/h6-8H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237963 (CHEMBL4098180) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(C)(=O)=O)ccc12 Show InChI InChI=1S/C12H9NO5S/c1-7-9-4-3-8(18-19(2,15)16)5-11(9)17-12(14)10(7)6-13/h3-5H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237922 (CHEMBL4103420) Show SMILES COc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 Show InChI InChI=1S/C17H13ClO6S/c1-10-14-8-5-12(9-15(14)23-17(19)16(10)18)24-25(20,21)13-6-3-11(22-2)4-7-13/h3-9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 3-4 nM				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237937 (CHEMBL1372043) Show SMILES Cc1cc(=O)oc2c(OS(C)(=O)=O)c(OS(C)(=O)=O)ccc12 Show InChI InChI=1S/C12H12O8S2/c1-7-6-10(13)18-11-8(7)4-5-9(19-21(2,14)15)12(11)20-22(3,16)17/h4-6H,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237926 (CHEMBL4080152) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3cc(Cl)ccc3Cl)ccc12 Show InChI InChI=1S/C17H9Cl2NO5S/c1-9-12-4-3-11(7-15(12)24-17(21)13(9)8-20)25-26(22,23)16-6-10(18)2-5-14(16)19/h2-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237918 (CHEMBL4093867) Show SMILES Cc1cc(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)c(c3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C16H10ClNO7S/c1-9-6-16(19)24-15-7-10(2-4-12(9)15)25-26(22,23)11-3-5-13(17)14(8-11)18(20)21/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237913 (CHEMBL4091160) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3cccc(c3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C17H10N2O7S/c1-10-14-6-5-12(8-16(14)25-17(20)15(10)9-18)26-27(23,24)13-4-2-3-11(7-13)19(21)22/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237926 (CHEMBL4080152) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3cc(Cl)ccc3Cl)ccc12 Show InChI InChI=1S/C17H9Cl2NO5S/c1-9-12-4-3-11(7-15(12)24-17(21)13(9)8-20)25-26(22,23)16-6-10(18)2-5-14(16)19/h2-7H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237941 (CHEMBL4073985) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(C)(=O)=O)ccc12 Show InChI InChI=1S/C11H9ClO5S/c1-6-8-4-3-7(17-18(2,14)15)5-9(8)16-11(13)10(6)12/h3-5H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237945 (CHEMBL4070218) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C17H10ClNO5S/c1-10-14-7-4-12(8-16(14)23-17(20)15(10)9-19)24-25(21,22)13-5-2-11(18)3-6-13/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell line				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237966 (CHEMBL4078377) Show SMILES CCCCCCCCc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1[N+]([O-])=O Show InChI InChI=1S/C24H27NO7S/c1-3-4-5-6-7-8-9-18-10-12-19(13-11-18)33(29,30)32-21-15-14-20-17(2)16-22(26)31-24(20)23(21)25(27)28/h10-16H,3-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237924 (CHEMBL4102277) Show SMILES CCCCCCCCS(=O)(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 Show InChI InChI=1S/C18H23ClO5S/c1-3-4-5-6-7-8-11-25(21,22)24-14-9-10-15-13(2)17(19)18(20)23-16(15)12-14/h9-10,12H,3-8,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237967 (CHEMBL4073185) Show SMILES COc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1OS(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C24H20O10S2/c1-15-14-22(25)32-23-20(15)12-13-21(33-35(26,27)18-8-4-16(30-2)5-9-18)24(23)34-36(28,29)19-10-6-17(31-3)7-11-19/h4-14H,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237918 (CHEMBL4093867) Show SMILES Cc1cc(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)c(c3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C16H10ClNO7S/c1-9-6-16(19)24-15-7-10(2-4-12(9)15)25-26(22,23)11-3-5-13(17)14(8-11)18(20)21/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237964 (CHEMBL4090465) Show SMILES CCCCCCCCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C19H23NO5S/c1-3-4-5-6-7-8-11-26(22,23)25-15-9-10-16-14(2)17(13-20)19(21)24-18(16)12-15/h9-10,12H,3-8,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237923 (CHEMBL4075025) Show SMILES CCS(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1OS(=O)(=O)CC Show InChI InChI=1S/C14H16O8S2/c1-4-23(16,17)21-11-7-6-10-9(3)8-12(15)20-13(10)14(11)22-24(18,19)5-2/h6-8H,4-5H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell line				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237966 (CHEMBL4078377) Show SMILES CCCCCCCCc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1[N+]([O-])=O Show InChI InChI=1S/C24H27NO7S/c1-3-4-5-6-7-8-9-18-10-12-19(13-11-18)33(29,30)32-21-15-14-20-17(2)16-22(26)31-24(20)23(21)25(27)28/h10-16H,3-9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237924 (CHEMBL4102277) Show SMILES CCCCCCCCS(=O)(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 Show InChI InChI=1S/C18H23ClO5S/c1-3-4-5-6-7-8-11-25(21,22)24-14-9-10-15-13(2)17(19)18(20)23-16(15)12-14/h9-10,12H,3-8,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237920 (CHEMBL4087225) Show SMILES Cc1cc(=O)oc2c(OS(=O)(=O)c3cc(Cl)ccc3Cl)c(OS(=O)(=O)c3cc(Cl)ccc3Cl)ccc12 Show InChI InChI=1S/C22H12Cl4O8S2/c1-11-8-20(27)32-21-14(11)4-7-17(33-35(28,29)18-9-12(23)2-5-15(18)25)22(21)34-36(30,31)19-10-13(24)3-6-16(19)26/h2-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR)				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237928 (CHEMBL4084312) Show SMILES CCCCS(=O)(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 Show InChI InChI=1S/C14H15ClO5S/c1-3-4-7-21(17,18)20-10-5-6-11-9(2)13(15)14(16)19-12(11)8-10/h5-6,8H,3-4,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237927 (CHEMBL4086809) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C17H11NO5S/c1-11-14-8-7-12(9-16(14)22-17(19)15(11)10-18)23-24(20,21)13-5-3-2-4-6-13/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237941 (CHEMBL4073985) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(C)(=O)=O)ccc12 Show InChI InChI=1S/C11H9ClO5S/c1-6-8-4-3-7(17-18(2,14)15)5-9(8)16-11(13)10(6)12/h3-5H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237925 (CHEMBL4103223) Show SMILES COc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C18H13NO6S/c1-11-15-8-5-13(9-17(15)24-18(20)16(11)10-19)25-26(21,22)14-6-3-12(23-2)4-7-14/h3-9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237944 (CHEMBL4094013) Show SMILES Cc1cc(=O)oc2c(OS(=O)(=O)c3ccc(Cl)cc3)c(OS(=O)(=O)c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C22H14Cl2O8S2/c1-13-12-20(25)30-21-18(13)10-11-19(31-33(26,27)16-6-2-14(23)3-7-16)22(21)32-34(28,29)17-8-4-15(24)5-9-17/h2-12H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237947 (CHEMBL4083749) Show SMILES Cc1ccc(cc1S(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1)[N+]([O-])=O Show InChI InChI=1S/C17H13NO7S/c1-10-3-4-12(18(20)21)8-16(10)26(22,23)25-13-5-6-14-11(2)7-17(19)24-15(14)9-13/h3-9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237965 (CHEMBL4068298) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)c(c3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C16H9Cl2NO7S/c1-8-11-4-2-9(6-14(11)25-16(20)15(8)18)26-27(23,24)10-3-5-12(17)13(7-10)19(21)22/h2-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237917 (CHEMBL4059741) Show SMILES CCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C13H11NO5S/c1-3-20(16,17)19-9-4-5-10-8(2)11(7-14)13(15)18-12(10)6-9/h4-6H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell line				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237921 (CHEMBL4065375) Show SMILES CCS(=O)(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 Show InChI InChI=1S/C12H11ClO5S/c1-3-19(15,16)18-8-4-5-9-7(2)11(13)12(14)17-10(9)6-8/h4-6H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 1273-2947 nM				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237939 (CHEMBL4077330) Show SMILES Cc1cc(=O)oc2c(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)c(OS(=O)(=O)c3ccc(cc3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C22H14N2O12S2/c1-13-12-20(25)34-21-18(13)10-11-19(35-37(30,31)16-6-2-14(3-7-16)23(26)27)22(21)36-38(32,33)17-8-4-15(5-9-17)24(28)29/h2-12H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237929 (CHEMBL4082634) Show SMILES CCCc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C20H17NO5S/c1-3-4-14-5-8-16(9-6-14)27(23,24)26-15-7-10-17-13(2)18(12-21)20(22)25-19(17)11-15/h5-11H,3-4H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237943 (CHEMBL4086241) Show SMILES Cc1cc(=O)oc2c(c(OS(=O)(=O)c3ccc(Cl)c(c3)[N+]([O-])=O)ccc12)[N+]([O-])=O Show InChI InChI=1S/C16H9ClN2O9S/c1-8-6-14(20)27-16-10(8)3-5-13(15(16)19(23)24)28-29(25,26)9-2-4-11(17)12(7-9)18(21)22/h2-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237913 (CHEMBL4091160) Show SMILES Cc1c(C#N)c(=O)oc2cc(OS(=O)(=O)c3cccc(c3)[N+]([O-])=O)ccc12 Show InChI InChI=1S/C17H10N2O7S/c1-10-14-6-5-12(8-16(14)25-17(20)15(10)9-18)26-27(23,24)13-4-2-3-11(7-13)19(21)22/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237962 (CHEMBL4079164) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(=O)(=O)c3ccccc3[N+]([O-])=O)ccc12 Show InChI InChI=1S/C16H10ClNO7S/c1-9-11-7-6-10(8-13(11)24-16(19)15(9)17)25-26(22,23)14-5-3-2-4-12(14)18(20)21/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237960 (CHEMBL4103132) Show SMILES Cc1c(Cl)c(=O)oc2cc(OS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C16H11ClO5S/c1-10-13-8-7-11(9-14(13)21-16(18)15(10)17)22-23(19,20)12-5-3-2-4-6-12/h2-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237919 (CHEMBL4101742) Show SMILES CCCc1ccc(cc1)S(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1OS(=O)(=O)c1ccc(CCC)cc1 Show InChI InChI=1S/C28H28O8S2/c1-4-6-20-8-12-22(13-9-20)37(30,31)35-25-17-16-24-19(3)18-26(29)34-27(24)28(25)36-38(32,33)23-14-10-21(7-5-2)11-15-23/h8-18H,4-7H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell line				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Homo sapiens (Human))	BDBM50237961 (CHEMBL4060753) Show SMILES CCCCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 Show InChI InChI=1S/C15H15NO5S/c1-3-4-7-22(18,19)21-11-5-6-12-10(2)13(9-16)15(17)20-14(12)8-11/h5-6,8H,3-4,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...				Eur J Med Chem 131: 29-47 (2017) Article DOI: 10.1016/j.ejmech.2017.03.003 BindingDB Entry DOI: 10.7270/Q2MS3W2X
					More data for this Ligand-Target Pair

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