Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50000362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247541 (CHEMBL4086109) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1F)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(14(9-24-11)12-4-2-3-5-13(12)19)16-7-6-15-18(20-16)21-17(23)10-25-15/h2-7,11,14H,8-10H2,1H3,(H,20,21,23)/t11-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50235963 (CHEMBL4097160) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C19H20N2O3/c1-13-10-21(17(11-23-13)14-5-3-2-4-6-14)15-7-8-18-16(9-15)20-19(22)12-24-18/h2-9,13,17H,10-12H2,1H3,(H,20,22)/t13-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247540 (CHEMBL4064593) Show SMILES C[C@@H]1CN([C@@H](CO1)c1cccc(F)c1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(14(9-24-11)12-3-2-4-13(19)7-12)16-6-5-15-18(20-16)21-17(23)10-25-15/h2-7,11,14H,8-10H2,1H3,(H,20,21,23)/t11-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50235963 (CHEMBL4097160) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C19H20N2O3/c1-13-10-21(17(11-23-13)14-5-3-2-4-6-14)15-7-8-18-16(9-15)20-19(22)12-24-18/h2-9,13,17H,10-12H2,1H3,(H,20,22)/t13-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247541 (CHEMBL4086109) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1F)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(14(9-24-11)12-4-2-3-5-13(12)19)16-7-6-15-18(20-16)21-17(23)10-25-15/h2-7,11,14H,8-10H2,1H3,(H,20,21,23)/t11-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247547 (CHEMBL4078214) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccc(F)cc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(14(9-24-11)12-2-4-13(19)5-3-12)16-7-6-15-18(20-16)21-17(23)10-25-15/h2-7,11,14H,8-10H2,1H3,(H,20,21,23)/t11-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247540 (CHEMBL4064593) Show SMILES C[C@@H]1CN([C@@H](CO1)c1cccc(F)c1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(14(9-24-11)12-3-2-4-13(19)7-12)16-6-5-15-18(20-16)21-17(23)10-25-15/h2-7,11,14H,8-10H2,1H3,(H,20,21,23)/t11-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247545 (CHEMBL4100538) Show SMILES O=C1COc2ccc(nc2N1)N1C[C@@H](CC#N)OC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O3/c20-9-8-14-10-23(15(11-25-14)13-4-2-1-3-5-13)17-7-6-16-19(21-17)22-18(24)12-26-16/h1-7,14-15H,8,10-12H2,(H,21,22,24)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247546 (CHEMBL4082524) Show SMILES CC1(C)CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C19H21N3O3/c1-19(2)12-22(14(10-25-19)13-6-4-3-5-7-13)16-9-8-15-18(20-16)21-17(23)11-24-15/h3-9,14H,10-12H2,1-2H3,(H,20,21,23)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247545 (CHEMBL4100538) Show SMILES O=C1COc2ccc(nc2N1)N1C[C@@H](CC#N)OC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O3/c20-9-8-14-10-23(15(11-25-14)13-4-2-1-3-5-13)17-7-6-16-19(21-17)22-18(24)12-26-16/h1-7,14-15H,8,10-12H2,(H,21,22,24)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247547 (CHEMBL4078214) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccc(F)cc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(14(9-24-11)12-2-4-13(19)5-3-12)16-7-6-15-18(20-16)21-17(23)10-25-15/h2-7,11,14H,8-10H2,1H3,(H,20,21,23)/t11-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247543 (CHEMBL4098088) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1cc2NC(=O)COc2cn1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(15(10-23-12)13-5-3-2-4-6-13)17-7-14-16(8-19-17)24-11-18(22)20-14/h2-8,12,15H,9-11H2,1H3,(H,20,22)/t12-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247548 (CHEMBL4079143) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ncc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C17H18N4O3/c1-11-8-21(13(9-23-11)12-5-3-2-4-6-12)17-18-7-14-16(20-17)19-15(22)10-24-14/h2-7,11,13H,8-10H2,1H3,(H,18,19,20,22)/t11-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247543 (CHEMBL4098088) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1cc2NC(=O)COc2cn1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(15(10-23-12)13-5-3-2-4-6-13)17-7-14-16(8-19-17)24-11-18(22)20-14/h2-8,12,15H,9-11H2,1H3,(H,20,22)/t12-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247548 (CHEMBL4079143) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ncc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C17H18N4O3/c1-11-8-21(13(9-23-11)12-5-3-2-4-6-12)17-18-7-14-16(20-17)19-15(22)10-24-14/h2-7,11,13H,8-10H2,1H3,(H,18,19,20,22)/t11-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247544 (CHEMBL4059632) Show SMILES COC[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C19H21N3O4/c1-24-10-14-9-22(15(11-25-14)13-5-3-2-4-6-13)17-8-7-16-19(20-17)21-18(23)12-26-16/h2-8,14-15H,9-12H2,1H3,(H,20,21,23)/t14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	276	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247544 (CHEMBL4059632) Show SMILES COC[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C19H21N3O4/c1-24-10-14-9-22(15(11-25-14)13-5-3-2-4-6-13)17-8-7-16-19(20-17)21-18(23)12-26-16/h2-8,14-15H,9-12H2,1H3,(H,20,21,23)/t14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	358	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247538 (CHEMBL4062345) Show SMILES O=C1COc2ccc(cc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C18H18N2O3/c21-18-12-23-17-7-6-14(10-15(17)19-18)20-8-9-22-11-16(20)13-4-2-1-3-5-13/h1-7,10,16H,8-9,11-12H2,(H,19,21)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	401	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247546 (CHEMBL4082524) Show SMILES CC1(C)CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C19H21N3O3/c1-19(2)12-22(14(10-25-19)13-6-4-3-5-7-13)16-9-8-15-18(20-16)21-17(23)11-24-15/h3-9,14H,10-12H2,1-2H3,(H,20,21,23)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247538 (CHEMBL4062345) Show SMILES O=C1COc2ccc(cc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C18H18N2O3/c21-18-12-23-17-7-6-14(10-15(17)19-18)20-8-9-22-11-16(20)13-4-2-1-3-5-13/h1-7,10,16H,8-9,11-12H2,(H,19,21)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	597	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to GR (unknown origin) expressed in human IM9 cells				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247552 (CHEMBL4062371) Show SMILES C[C@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	727	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50235975 (CHEMBL4079083) Show SMILES O=C1COc2ccc(nc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C17H17N3O3/c21-16-11-23-14-6-7-15(18-17(14)19-16)20-8-9-22-10-13(20)12-4-2-1-3-5-12/h1-7,13H,8-11H2,(H,18,19,21)/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247552 (CHEMBL4062371) Show SMILES C[C@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50235975 (CHEMBL4079083) Show SMILES O=C1COc2ccc(nc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C17H17N3O3/c21-16-11-23-14-6-7-15(18-17(14)19-16)20-8-9-22-10-13(20)12-4-2-1-3-5-12/h1-7,13H,8-11H2,(H,18,19,21)/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247542 (CHEMBL4071008) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1cnc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(16(10-23-12)13-5-3-2-4-6-13)14-7-15-18(19-8-14)24-11-17(22)20-15/h2-8,12,16H,9-11H2,1H3,(H,20,22)/t12-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247542 (CHEMBL4071008) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1cnc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(16(10-23-12)13-5-3-2-4-6-13)14-7-15-18(19-8-14)24-11-17(22)20-15/h2-8,12,16H,9-11H2,1H3,(H,20,22)/t12-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused AR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-dexamethasone from recombinant human GST-tagged GR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50247538 (CHEMBL4062345) Show SMILES O=C1COc2ccc(cc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C18H18N2O3/c21-18-12-23-17-7-6-14(10-15(17)19-18)20-8-9-22-11-16(20)13-4-2-1-3-5-13/h1-7,10,16H,8-9,11-12H2,(H,19,21)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused AR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247549 (CHEMBL4081584) Show SMILES OC[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O4/c22-9-13-8-21(14(10-24-13)12-4-2-1-3-5-12)16-7-6-15-18(19-16)20-17(23)11-25-15/h1-7,13-14,22H,8-11H2,(H,19,20,23)/t13-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50247538 (CHEMBL4062345) Show SMILES O=C1COc2ccc(cc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C18H18N2O3/c21-18-12-23-17-7-6-14(10-15(17)19-18)20-8-9-22-11-16(20)13-4-2-1-3-5-13/h1-7,10,16H,8-9,11-12H2,(H,19,21)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at GR (unknown origin) by Gal4-based cellular assay				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at GR (unknown origin) by Gal4-based cellular assay				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at PR (unknown origin) by Gal4-based cellular assay				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50247538 (CHEMBL4062345) Show SMILES O=C1COc2ccc(cc2N1)N1CCOC[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C18H18N2O3/c21-18-12-23-17-7-6-14(10-15(17)19-18)20-8-9-22-11-16(20)13-4-2-1-3-5-13/h1-7,10,16H,8-9,11-12H2,(H,19,21)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at PR (unknown origin) by Gal4-based cellular assay				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50247549 (CHEMBL4081584) Show SMILES OC[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O4/c22-9-13-8-21(14(10-24-13)12-4-2-1-3-5-12)16-7-6-15-18(19-16)20-17(23)11-25-15/h1-7,13-14,22H,8-11H2,(H,19,20,23)/t13-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to ERalpha (unknown origin)				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-progesterone from recombinant human His-tagged PR-b after 4 hrs by liquid scintillation counting				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to AR (unknown origin)				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair