Compile Data Set for Download or QSAR

Found 93 hits Enz. Inhib. hit(s) with all data for entry = 50036993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102271 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-5,9,9b-tri...) Show SMILES Brc1ccc(NC(=S)NCCn2c3cccnc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-15(22-11-12)23-18(27)21-8-10-25-13-3-1-7-20-16(13)24-9-2-4-14(24)17(25)26/h1-7,9,11H,8,10H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102265 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2c1n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-17-13(21)3-1-4-14(17)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102265 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2c1n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-17-13(21)3-1-4-14(17)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102268 (1-(5-Bromo-pyridin-2-yl)-3-[2-(5-oxo-pyrazolo[1,5-...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3c3ccnn3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-16(21-11-12)23-17(27)20-9-10-24-14-4-2-1-3-13(14)15-7-8-22-25(15)18(24)26/h1-8,11H,9-10H2,(H2,20,21,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102276 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-4-oxo-4H-p...) Show SMILES Clc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102276 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-4-oxo-4H-p...) Show SMILES Clc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102268 (1-(5-Bromo-pyridin-2-yl)-3-[2-(5-oxo-pyrazolo[1,5-...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3c3ccnn3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-16(21-11-12)23-17(27)20-9-10-24-14-4-2-1-3-13(14)15-7-8-22-25(15)18(24)26/h1-8,11H,9-10H2,(H2,20,21,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102277 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7,9-difluoro-4-oxo-...) Show SMILES Fc1cc(F)c2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H14BrF2N5OS/c20-11-3-4-16(24-10-11)25-19(29)23-5-7-27-15-9-12(21)8-13(22)17(15)26-6-1-2-14(26)18(27)28/h1-4,6,8-10H,5,7H2,(H2,23,24,25,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102266 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...) Show SMILES Fc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102273 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-pyrrolo[1,...) Show SMILES Fc1cccc2c1nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-27-18-15-5-2-9-26(15)14-4-1-3-13(21)17(14)25-18/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102277 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7,9-difluoro-4-oxo-...) Show SMILES Fc1cc(F)c2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H14BrF2N5OS/c20-11-3-4-16(24-10-11)25-19(29)23-5-7-27-15-9-12(21)8-13(22)17(15)26-6-1-2-14(26)18(27)28/h1-4,6,8-10H,5,7H2,(H2,23,24,25,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 |r| Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102270 (1-(5-Bromo-pyridin-2-yl)-3-[2-(9-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2n(CCNC(=S)Nc3ccc(Br)cn3)c(=O)c3cccn3c12 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-14-4-1-3-13(21)17(14)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 |r| Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102266 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-fluoro-4-oxo-4H-p...) Show SMILES Fc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102271 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-5,9,9b-tri...) Show SMILES Brc1ccc(NC(=S)NCCn2c3cccnc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-15(22-11-12)23-18(27)21-8-10-25-13-3-1-7-20-16(13)24-9-2-4-14(24)17(25)26/h1-7,9,11H,8,10H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102273 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-pyrrolo[1,...) Show SMILES Fc1cccc2c1nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-27-18-15-5-2-9-26(15)14-4-1-3-13(21)17(14)25-18/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102275 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-pyrrolo[1,...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C19H16BrN5OS/c20-13-7-8-17(22-12-13)23-19(27)21-9-11-25-15-5-2-1-4-14(15)24-10-3-6-16(24)18(25)26/h1-8,10,12H,9,11H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102270 (1-(5-Bromo-pyridin-2-yl)-3-[2-(9-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2n(CCNC(=S)Nc3ccc(Br)cn3)c(=O)c3cccn3c12 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-14-4-1-3-13(21)17(14)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V179D				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y181I				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102271 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-5,9,9b-tri...) Show SMILES Brc1ccc(NC(=S)NCCn2c3cccnc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-15(22-11-12)23-18(27)21-8-10-25-13-3-1-7-20-16(13)24-9-2-4-14(24)17(25)26/h1-7,9,11H,8,10H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102275 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-pyrrolo[1,...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C19H16BrN5OS/c20-13-7-8-17(22-12-13)23-19(27)21-9-11-25-15-5-2-1-4-14(15)24-10-3-6-16(24)18(25)26/h1-8,10,12H,9,11H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102277 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7,9-difluoro-4-oxo-...) Show SMILES Fc1cc(F)c2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H14BrF2N5OS/c20-11-3-4-16(24-10-11)25-19(29)23-5-7-27-15-9-12(21)8-13(22)17(15)26-6-1-2-14(26)18(27)28/h1-4,6,8-10H,5,7H2,(H2,23,24,25,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y188L				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102268 (1-(5-Bromo-pyridin-2-yl)-3-[2-(5-oxo-pyrazolo[1,5-...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3c3ccnn3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-16(21-11-12)23-17(27)20-9-10-24-14-4-2-1-3-13(14)15-7-8-22-25(15)18(24)26/h1-8,11H,9-10H2,(H2,20,21,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102275 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-pyrrolo[1,...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C19H16BrN5OS/c20-13-7-8-17(22-12-13)23-19(27)21-9-11-25-15-5-2-1-4-14(15)24-10-3-6-16(24)18(25)26/h1-8,10,12H,9,11H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102275 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-pyrrolo[1,...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C19H16BrN5OS/c20-13-7-8-17(22-12-13)23-19(27)21-9-11-25-15-5-2-1-4-14(15)24-10-3-6-16(24)18(25)26/h1-8,10,12H,9,11H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 |r| Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102271 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-5,9,9b-tri...) Show SMILES Brc1ccc(NC(=S)NCCn2c3cccnc3n3cccc3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-15(22-11-12)23-18(27)21-8-10-25-13-3-1-7-20-16(13)24-9-2-4-14(24)17(25)26/h1-7,9,11H,8,10H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y188L				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102273 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-pyrrolo[1,...) Show SMILES Fc1cccc2c1nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-27-18-15-5-2-9-26(15)14-4-1-3-13(21)17(14)25-18/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102274 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7,8-dimethyl-pyrrol...) Show SMILES Cc1cc2nc(OCCNC(=S)Nc3ccc(Br)cn3)c3cccn3c2cc1C Show InChI InChI=1S/C21H20BrN5OS/c1-13-10-16-18(11-14(13)2)27-8-3-4-17(27)20(25-16)28-9-7-23-21(29)26-19-6-5-15(22)12-24-19/h3-6,8,10-12H,7,9H2,1-2H3,(H2,23,24,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution V106A				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 |r| Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y181I				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102276 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-4-oxo-4H-p...) Show SMILES Clc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 |r| Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102265 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2c1n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-17-13(21)3-1-4-14(17)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102276 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-4-oxo-4H-p...) Show SMILES Clc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102265 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2c1n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-17-13(21)3-1-4-14(17)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution L1001				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102264 (CHEMBL322698 | Pyrazine-2-carboxylic acid N'-pyrro...) Show SMILES O=C(NNc1nc2ccccc2n2cccc12)c1cnccn1 Show InChI InChI=1S/C16H12N6O/c23-16(12-10-17-7-8-18-12)21-20-15-14-6-3-9-22(14)13-5-2-1-4-11(13)19-15/h1-10H,(H,19,20)(H,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102265 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2c1n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-17-13(21)3-1-4-14(17)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y181I				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102270 (1-(5-Bromo-pyridin-2-yl)-3-[2-(9-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2n(CCNC(=S)Nc3ccc(Br)cn3)c(=O)c3cccn3c12 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-14-4-1-3-13(21)17(14)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y188L				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102265 (1-(5-Bromo-pyridin-2-yl)-3-[2-(6-fluoro-4-oxo-4H-p...) Show SMILES Fc1cccc2c1n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrFN5OS/c20-12-6-7-16(23-11-12)24-19(28)22-8-10-26-17-13(21)3-1-4-14(17)25-9-2-5-15(25)18(26)27/h1-7,9,11H,8,10H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y188L				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102267 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-pyrrolo[1,...) Show SMILES Clc1ccc2c(c1)nc(OCCNC(=S)Nc1ccc(Br)cn1)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)25-19(28)22-7-9-27-18-16-2-1-8-26(16)15-5-4-13(21)10-14(15)24-18/h1-6,8,10-11H,7,9H2,(H2,22,23,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102274 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7,8-dimethyl-pyrrol...) Show SMILES Cc1cc2nc(OCCNC(=S)Nc3ccc(Br)cn3)c3cccn3c2cc1C Show InChI InChI=1S/C21H20BrN5OS/c1-13-10-16-18(11-14(13)2)27-8-3-4-17(27)20(25-16)28-9-7-23-21(29)26-19-6-5-15(22)12-24-19/h3-6,8,10-12H,7,9H2,1-2H3,(H2,23,24,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102276 (1-(5-Bromo-pyridin-2-yl)-3-[2-(7-chloro-4-oxo-4H-p...) Show SMILES Clc1ccc2c(c1)n(CCNC(=S)Nc1ccc(Br)cn1)c(=O)c1cccn21 Show InChI InChI=1S/C19H15BrClN5OS/c20-12-3-6-17(23-11-12)24-19(28)22-7-9-26-16-10-13(21)4-5-14(16)25-8-1-2-15(25)18(26)27/h1-6,8,10-11H,7,9H2,(H2,22,23,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution Y181I				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102272 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-imidazo[1,...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3n3ccnc3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-15(22-11-12)23-18(27)21-8-10-25-14-4-2-1-3-13(14)24-9-7-20-16(24)17(25)26/h1-7,9,11H,8,10H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 Mutant HIV-1 RT enzymes containing the single amino acid substitution K103N				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50102272 (1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-imidazo[1,...) Show SMILES Brc1ccc(NC(=S)NCCn2c3ccccc3n3ccnc3c2=O)nc1 Show InChI InChI=1S/C18H15BrN6OS/c19-12-5-6-15(22-11-12)23-18(27)21-8-10-25-14-4-2-1-3-13(14)24-9-7-20-16(24)17(25)26/h1-7,9,11H,8,10H2,(H2,21,22,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Inhibition of HIV-1 wild-type RT				J Med Chem 44: 305-15 (2001) BindingDB Entry DOI: 10.7270/Q2HX1DD9
					More data for this Ligand-Target Pair

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