Found 120 hits Enz. Inhib. hit(s) with all data for entry = 50037040 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 3
(Mus musculus) | BDBM50115373
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,26.27,wD:37.38,(23.38,-8.66,;23.38,-10.2,;22.06,-10.96,;24.72,-10.97,;26.05,-10.21,;26.05,-8.66,;27.39,-7.89,;28.79,-8.52,;29.83,-7.38,;29.06,-6.04,;27.55,-6.36,;27.39,-10.97,;27.39,-12.51,;28.72,-10.21,;30.06,-10.97,;30.06,-12.51,;31.39,-13.29,;32.73,-12.51,;34.05,-13.29,;34.05,-14.83,;35.38,-15.6,;32.72,-15.59,;31.39,-14.82,;31.39,-10.21,;31.39,-8.66,;32.72,-10.97,;34.05,-10.2,;34.05,-8.67,;35.38,-7.89,;35.38,-6.36,;36.72,-5.59,;36.72,-4.06,;35.39,-3.28,;38.06,-3.28,;35.38,-10.97,;35.38,-12.52,;36.72,-10.21,;38.06,-10.98,;38.06,-12.52,;39.39,-13.3,;40.8,-12.67,;41.82,-13.82,;41.06,-15.15,;41.52,-16.62,;40.5,-17.76,;38.99,-17.44,;38.51,-15.97,;39.55,-14.83,;39.39,-10.22,;40.73,-10.98,;39.39,-8.68,)| Show InChI InChI=1S/C34H42IN11O5/c1-19(47)43-29(15-23-17-39-18-42-23)33(51)46-28(13-20-8-10-22(35)11-9-20)32(50)44-26(7-4-12-40-34(37)38)31(49)45-27(30(36)48)14-21-16-41-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,41H,4,7,12-15H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28+,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Binding constant (Ki) at mouse Melanocortin-3 receptor |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115362
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-27-20-42-21-45-27)37(54)49-32(16-23-12-13-24-7-2-3-8-25(24)15-23)36(53)47-30(11-6-14-43-38(40)41)35(52)48-31(34(39)51)17-26-19-44-29-10-5-4-9-28(26)29/h2-5,7-10,12-13,15,19-21,30-33,44H,6,11,14,16-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32+,33-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 295 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Binding constant (Ki) at mouse Melanocortin-3 receptor |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115360
(2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylami...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H45N11O5/c1-21(48)44-30(16-25-19-40-20-43-25)33(51)47-36(13-12-22-7-2-3-8-23(22)17-36)34(52)46-28(11-6-14-41-35(38)39)32(50)45-29(31(37)49)15-24-18-42-27-10-5-4-9-26(24)27/h2-5,7-10,18-20,28-30,42H,6,11-17H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,50)(H,46,52)(H,47,51)(H4,38,39,41)/t28-,29-,30-,36?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115361
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C28H39N11O5/c1-15(36-27(44)23(37-16(2)40)11-18-13-32-14-35-18)25(42)38-21(8-5-9-33-28(30)31)26(43)39-22(24(29)41)10-17-12-34-20-7-4-3-6-19(17)20/h3-4,6-7,12-15,21-23,34H,5,8-11H2,1-2H3,(H2,29,41)(H,32,35)(H,36,44)(H,37,40)(H,38,42)(H,39,43)(H4,30,31,33)/t15-,21-,22-,23-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115363
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N12O5/c1-20(49)45-31(15-23-18-40-19-44-23)35(53)48-30(14-22-17-43-27-10-5-3-8-25(22)27)34(52)46-28(11-6-12-41-36(38)39)33(51)47-29(32(37)50)13-21-16-42-26-9-4-2-7-24(21)26/h2-5,7-10,16-19,28-31,42-43H,6,11-15H2,1H3,(H2,37,50)(H,40,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.43E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115362
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-27-20-42-21-45-27)37(54)49-32(16-23-12-13-24-7-2-3-8-25(24)15-23)36(53)47-30(11-6-14-43-38(40)41)35(52)48-31(34(39)51)17-26-19-44-29-10-5-4-9-28(26)29/h2-5,7-10,12-13,15,19-21,30-33,44H,6,11,14,16-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32+,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 167 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115364
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O6/c1-19(46)42-29(15-22-17-38-18-41-22)33(51)45-28(13-20-8-10-23(47)11-9-20)32(50)43-26(7-4-12-39-34(36)37)31(49)44-27(30(35)48)14-21-16-40-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,40,47H,4,7,12-15H2,1H3,(H2,35,48)(H,38,41)(H,42,46)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115364
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O6/c1-19(46)42-29(15-22-17-38-18-41-22)33(51)45-28(13-20-8-10-23(47)11-9-20)32(50)43-26(7-4-12-39-34(36)37)31(49)44-27(30(35)48)14-21-16-40-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,40,47H,4,7,12-15H2,1H3,(H2,35,48)(H,38,41)(H,42,46)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115360
(2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylami...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H45N11O5/c1-21(48)44-30(16-25-19-40-20-43-25)33(51)47-36(13-12-22-7-2-3-8-23(22)17-36)34(52)46-28(11-6-14-41-35(38)39)32(50)45-29(31(37)49)15-24-18-42-27-10-5-4-9-26(24)27/h2-5,7-10,18-20,28-30,42H,6,11-17H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,50)(H,46,52)(H,47,51)(H4,38,39,41)/t28-,29-,30-,36?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.37 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115366
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,26.27,wD:37.38,(19.22,-37.32,;19.23,-38.86,;17.89,-39.63,;20.56,-39.63,;21.89,-38.86,;21.89,-37.32,;23.23,-36.54,;24.64,-37.17,;25.67,-36.02,;24.9,-34.69,;23.39,-35.01,;23.23,-39.63,;23.23,-41.17,;24.56,-38.86,;25.89,-39.63,;25.89,-41.17,;27.23,-41.94,;28.56,-41.16,;29.9,-41.93,;29.9,-43.48,;31.22,-44.24,;28.56,-44.25,;27.23,-43.47,;27.23,-38.86,;27.23,-37.32,;28.56,-39.63,;29.9,-38.86,;29.9,-37.32,;31.23,-36.54,;31.23,-35,;32.56,-34.23,;32.56,-32.69,;31.23,-31.92,;33.9,-31.92,;31.23,-39.63,;31.23,-41.17,;32.56,-38.86,;33.9,-39.63,;33.9,-41.17,;35.19,-42.01,;36.62,-41.45,;37.59,-42.66,;36.76,-43.94,;37.16,-45.43,;36.07,-46.52,;34.59,-46.12,;34.19,-44.63,;35.27,-43.54,;35.23,-38.86,;36.57,-39.63,;35.23,-37.32,)| Show InChI InChI=1S/C34H43N11O6/c1-19(46)42-29(15-22-17-38-18-41-22)33(51)45-28(13-20-8-10-23(47)11-9-20)32(50)43-26(7-4-12-39-34(36)37)31(49)44-27(30(35)48)14-21-16-40-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,40,47H,4,7,12-15H2,1H3,(H2,35,48)(H,38,41)(H,42,46)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t26-,27-,28+,29-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115365
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)c1ccccc1 Show InChI InChI=1S/C33H41N11O5/c1-19(45)41-27(15-22-17-37-18-40-22)31(48)44-28(20-8-3-2-4-9-20)32(49)42-25(12-7-13-38-33(35)36)30(47)43-26(29(34)46)14-21-16-39-24-11-6-5-10-23(21)24/h2-6,8-11,16-18,25-28,39H,7,12-15H2,1H3,(H2,34,46)(H,37,40)(H,41,45)(H,42,49)(H,43,47)(H,44,48)(H4,35,36,38)/t25-,26-,27-,28-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115369
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C33H42N12O5/c1-19(46)42-28(15-22-17-38-18-41-22)32(50)45-27(13-20-8-11-37-12-9-20)31(49)43-25(7-4-10-39-33(35)36)30(48)44-26(29(34)47)14-21-16-40-24-6-3-2-5-23(21)24/h2-3,5-6,8-9,11-12,16-18,25-28,40H,4,7,10,13-15H2,1H3,(H2,34,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,35,36,39)/t25-,26-,27-,28-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.44E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115370
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-27-20-42-21-45-27)37(54)49-32(16-23-12-13-24-7-2-3-8-25(24)15-23)36(53)47-30(11-6-14-43-38(40)41)35(52)48-31(34(39)51)17-26-19-44-29-10-5-4-9-28(26)29/h2-5,7-10,12-13,15,19-21,30-33,44H,6,11,14,16-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115367
((2S)-N-[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]-5...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C35H43N11O5/c1-20(47)43-29(15-24-17-39-19-42-24)34(51)46-18-22-8-3-2-7-21(22)14-30(46)33(50)44-27(11-6-12-40-35(37)38)32(49)45-28(31(36)48)13-23-16-41-26-10-5-4-9-25(23)26/h2-5,7-10,16-17,19,27-30,41H,6,11-15,18H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H4,37,38,40)/t27-,28-,29-,30?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.08E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115367
((2S)-N-[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]-5...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C35H43N11O5/c1-20(47)43-29(15-24-17-39-19-42-24)34(51)46-18-22-8-3-2-7-21(22)14-30(46)33(50)44-27(11-6-12-40-35(37)38)32(49)45-28(31(36)48)13-23-16-41-26-10-5-4-9-25(23)26/h2-5,7-10,16-17,19,27-30,41H,6,11-15,18H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H4,37,38,40)/t27-,28-,29-,30?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115362
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-27-20-42-21-45-27)37(54)49-32(16-23-12-13-24-7-2-3-8-25(24)15-23)36(53)47-30(11-6-14-43-38(40)41)35(52)48-31(34(39)51)17-26-19-44-29-10-5-4-9-28(26)29/h2-5,7-10,12-13,15,19-21,30-33,44H,6,11,14,16-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32+,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.78 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity of compound towards mouse Melanocortin-4 receptor (mMC4R); partial agonist |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50034922
((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,25.26,wD:36.37,(-8.22,-36.2,;-8.22,-37.74,;-9.55,-38.51,;-6.89,-38.5,;-5.56,-37.74,;-5.56,-36.2,;-4.23,-35.43,;-2.82,-36.06,;-1.79,-34.91,;-2.55,-33.58,;-4.06,-33.9,;-4.22,-38.5,;-4.22,-40.05,;-2.89,-37.73,;-1.56,-38.5,;-1.56,-40.04,;-.23,-40.81,;1.1,-40.05,;2.44,-40.82,;2.44,-42.35,;1.1,-43.12,;-.23,-42.35,;-.22,-37.73,;-.22,-36.19,;1.11,-38.5,;2.45,-37.74,;2.45,-36.2,;3.78,-35.43,;3.78,-33.89,;5.11,-33.12,;5.11,-31.58,;3.78,-30.82,;6.45,-30.82,;3.78,-38.51,;3.78,-40.05,;5.11,-37.73,;6.44,-38.51,;6.44,-40.05,;7.77,-40.82,;9.18,-40.2,;10.21,-41.34,;9.43,-42.67,;9.91,-44.14,;8.88,-45.29,;7.37,-44.97,;6.9,-43.5,;7.93,-42.35,;7.77,-37.74,;9.1,-38.51,;7.77,-36.2,)| Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28+,29-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 20.1 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115365
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)c1ccccc1 Show InChI InChI=1S/C33H41N11O5/c1-19(45)41-27(15-22-17-37-18-40-22)31(48)44-28(20-8-3-2-4-9-20)32(49)42-25(12-7-13-38-33(35)36)30(47)43-26(29(34)46)14-21-16-39-24-11-6-5-10-23(21)24/h2-6,8-11,16-18,25-28,39H,7,12-15H2,1H3,(H2,34,46)(H,37,40)(H,41,45)(H,42,49)(H,43,47)(H,44,48)(H4,35,36,38)/t25-,26-,27-,28-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.05E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115366
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,26.27,wD:37.38,(19.22,-37.32,;19.23,-38.86,;17.89,-39.63,;20.56,-39.63,;21.89,-38.86,;21.89,-37.32,;23.23,-36.54,;24.64,-37.17,;25.67,-36.02,;24.9,-34.69,;23.39,-35.01,;23.23,-39.63,;23.23,-41.17,;24.56,-38.86,;25.89,-39.63,;25.89,-41.17,;27.23,-41.94,;28.56,-41.16,;29.9,-41.93,;29.9,-43.48,;31.22,-44.24,;28.56,-44.25,;27.23,-43.47,;27.23,-38.86,;27.23,-37.32,;28.56,-39.63,;29.9,-38.86,;29.9,-37.32,;31.23,-36.54,;31.23,-35,;32.56,-34.23,;32.56,-32.69,;31.23,-31.92,;33.9,-31.92,;31.23,-39.63,;31.23,-41.17,;32.56,-38.86,;33.9,-39.63,;33.9,-41.17,;35.19,-42.01,;36.62,-41.45,;37.59,-42.66,;36.76,-43.94,;37.16,-45.43,;36.07,-46.52,;34.59,-46.12,;34.19,-44.63,;35.27,-43.54,;35.23,-38.86,;36.57,-39.63,;35.23,-37.32,)| Show InChI InChI=1S/C34H43N11O6/c1-19(46)42-29(15-22-17-38-18-41-22)33(51)45-28(13-20-8-10-23(47)11-9-20)32(50)43-26(7-4-12-39-34(36)37)31(49)44-27(30(35)48)14-21-16-40-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,40,47H,4,7,12-15H2,1H3,(H2,35,48)(H,38,41)(H,42,46)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t26-,27-,28+,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115372
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C35H45N11O5/c1-21(47)43-30(17-24-19-39-20-42-24)34(51)45-28(14-13-22-8-3-2-4-9-22)33(50)44-27(12-7-15-40-35(37)38)32(49)46-29(31(36)48)16-23-18-41-26-11-6-5-10-25(23)26/h2-6,8-11,18-20,27-30,41H,7,12-17H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,51)(H,46,49)(H4,37,38,40)/t27-,28+,29-,30-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115360
(2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylami...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H45N11O5/c1-21(48)44-30(16-25-19-40-20-43-25)33(51)47-36(13-12-22-7-2-3-8-23(22)17-36)34(52)46-28(11-6-14-41-35(38)39)32(50)45-29(31(37)49)15-24-18-42-27-10-5-4-9-26(24)27/h2-5,7-10,18-20,28-30,42H,6,11-17H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,50)(H,46,52)(H,47,51)(H4,38,39,41)/t28-,29-,30-,36?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115363
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N12O5/c1-20(49)45-31(15-23-18-40-19-44-23)35(53)48-30(14-22-17-43-27-10-5-3-8-25(22)27)34(52)46-28(11-6-12-41-36(38)39)33(51)47-29(32(37)50)13-21-16-42-26-9-4-2-7-24(21)26/h2-5,7-10,16-19,28-31,42-43H,6,11-15H2,1H3,(H2,37,50)(H,40,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.84E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115374
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115375
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C40H47N11O5/c1-24(52)48-35(20-29-22-44-23-47-29)39(56)51-34(18-25-13-15-27(16-14-25)26-8-3-2-4-9-26)38(55)49-32(12-7-17-45-40(42)43)37(54)50-33(36(41)53)19-28-21-46-31-11-6-5-10-30(28)31/h2-6,8-11,13-16,21-23,32-35,46H,7,12,17-20H2,1H3,(H2,41,53)(H,44,47)(H,48,52)(H,49,55)(H,50,54)(H,51,56)(H4,42,43,45)/t32-,33-,34-,35-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0710 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115360
(2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylami...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H45N11O5/c1-21(48)44-30(16-25-19-40-20-43-25)33(51)47-36(13-12-22-7-2-3-8-23(22)17-36)34(52)46-28(11-6-14-41-35(38)39)32(50)45-29(31(37)49)15-24-18-42-27-10-5-4-9-26(24)27/h2-5,7-10,18-20,28-30,42H,6,11-17H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,50)(H,46,52)(H,47,51)(H4,38,39,41)/t28-,29-,30-,36?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115374
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115367
((2S)-N-[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]-5...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C35H43N11O5/c1-20(47)43-29(15-24-17-39-19-42-24)34(51)46-18-22-8-3-2-7-21(22)14-30(46)33(50)44-27(11-6-12-40-35(37)38)32(49)45-28(31(36)48)13-23-16-41-26-10-5-4-9-25(23)26/h2-5,7-10,16-17,19,27-30,41H,6,11-15,18H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H4,37,38,40)/t27-,28-,29-,30?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115360
(2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylami...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H45N11O5/c1-21(48)44-30(16-25-19-40-20-43-25)33(51)47-36(13-12-22-7-2-3-8-23(22)17-36)34(52)46-28(11-6-14-41-35(38)39)32(50)45-29(31(37)49)15-24-18-42-27-10-5-4-9-26(24)27/h2-5,7-10,18-20,28-30,42H,6,11-17H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,50)(H,46,52)(H,47,51)(H4,38,39,41)/t28-,29-,30-,36?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.13E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115369
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C33H42N12O5/c1-19(46)42-28(15-22-17-38-18-41-22)32(50)45-27(13-20-8-11-37-12-9-20)31(49)43-25(7-4-10-39-33(35)36)30(48)44-26(29(34)47)14-21-16-40-24-6-3-2-5-23(21)24/h2-3,5-6,8-9,11-12,16-18,25-28,40H,4,7,10,13-15H2,1H3,(H2,34,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,35,36,39)/t25-,26-,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50034922
((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,25.26,wD:36.37,(-8.22,-36.2,;-8.22,-37.74,;-9.55,-38.51,;-6.89,-38.5,;-5.56,-37.74,;-5.56,-36.2,;-4.23,-35.43,;-2.82,-36.06,;-1.79,-34.91,;-2.55,-33.58,;-4.06,-33.9,;-4.22,-38.5,;-4.22,-40.05,;-2.89,-37.73,;-1.56,-38.5,;-1.56,-40.04,;-.23,-40.81,;1.1,-40.05,;2.44,-40.82,;2.44,-42.35,;1.1,-43.12,;-.23,-42.35,;-.22,-37.73,;-.22,-36.19,;1.11,-38.5,;2.45,-37.74,;2.45,-36.2,;3.78,-35.43,;3.78,-33.89,;5.11,-33.12,;5.11,-31.58,;3.78,-30.82,;6.45,-30.82,;3.78,-38.51,;3.78,-40.05,;5.11,-37.73,;6.44,-38.51,;6.44,-40.05,;7.77,-40.82,;9.18,-40.2,;10.21,-41.34,;9.43,-42.67,;9.91,-44.14,;8.88,-45.29,;7.37,-44.97,;6.9,-43.5,;7.93,-42.35,;7.77,-37.74,;9.1,-38.51,;7.77,-36.2,)| Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28+,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 156 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50034922
((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,25.26,wD:36.37,(-8.22,-36.2,;-8.22,-37.74,;-9.55,-38.51,;-6.89,-38.5,;-5.56,-37.74,;-5.56,-36.2,;-4.23,-35.43,;-2.82,-36.06,;-1.79,-34.91,;-2.55,-33.58,;-4.06,-33.9,;-4.22,-38.5,;-4.22,-40.05,;-2.89,-37.73,;-1.56,-38.5,;-1.56,-40.04,;-.23,-40.81,;1.1,-40.05,;2.44,-40.82,;2.44,-42.35,;1.1,-43.12,;-.23,-42.35,;-.22,-37.73,;-.22,-36.19,;1.11,-38.5,;2.45,-37.74,;2.45,-36.2,;3.78,-35.43,;3.78,-33.89,;5.11,-33.12,;5.11,-31.58,;3.78,-30.82,;6.45,-30.82,;3.78,-38.51,;3.78,-40.05,;5.11,-37.73,;6.44,-38.51,;6.44,-40.05,;7.77,-40.82,;9.18,-40.2,;10.21,-41.34,;9.43,-42.67,;9.91,-44.14,;8.88,-45.29,;7.37,-44.97,;6.9,-43.5,;7.93,-42.35,;7.77,-37.74,;9.1,-38.51,;7.77,-36.2,)| Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28+,29-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.96 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115361
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C28H39N11O5/c1-15(36-27(44)23(37-16(2)40)11-18-13-32-14-35-18)25(42)38-21(8-5-9-33-28(30)31)26(43)39-22(24(29)41)10-17-12-34-20-7-4-3-6-19(17)20/h3-4,6-7,12-15,21-23,34H,5,8-11H2,1-2H3,(H2,29,41)(H,32,35)(H,36,44)(H,37,40)(H,38,42)(H,39,43)(H4,30,31,33)/t15-,21-,22-,23-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115378
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)c1ccccc1 Show InChI InChI=1S/C33H41N11O5/c1-19(45)41-27(15-22-17-37-18-40-22)31(48)44-28(20-8-3-2-4-9-20)32(49)42-25(12-7-13-38-33(35)36)30(47)43-26(29(34)46)14-21-16-39-24-11-6-5-10-23(21)24/h2-6,8-11,16-18,25-28,39H,7,12-15H2,1H3,(H2,34,46)(H,37,40)(H,41,45)(H,42,49)(H,43,47)(H,44,48)(H4,35,36,38)/t25-,26-,27-,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115377
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C40H47N11O5/c1-24(52)48-33(20-28-22-44-23-47-28)38(55)51-35(34(25-11-4-2-5-12-25)26-13-6-3-7-14-26)39(56)49-31(17-10-18-45-40(42)43)37(54)50-32(36(41)53)19-27-21-46-30-16-9-8-15-29(27)30/h2-9,11-16,21-23,31-35,46H,10,17-20H2,1H3,(H2,41,53)(H,44,47)(H,48,52)(H,49,56)(H,50,54)(H,51,55)(H4,42,43,45)/t31-,32-,33-,35+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115376
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32+,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 356 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115377
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C40H47N11O5/c1-24(52)48-33(20-28-22-44-23-47-28)38(55)51-35(34(25-11-4-2-5-12-25)26-13-6-3-7-14-26)39(56)49-31(17-10-18-45-40(42)43)37(54)50-32(36(41)53)19-27-21-46-30-16-9-8-15-29(27)30/h2-9,11-16,21-23,31-35,46H,10,17-20H2,1H3,(H2,41,53)(H,44,47)(H,48,52)(H,49,56)(H,50,54)(H,51,55)(H4,42,43,45)/t31-,32-,33-,35+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115364
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O6/c1-19(46)42-29(15-22-17-38-18-41-22)33(51)45-28(13-20-8-10-23(47)11-9-20)32(50)43-26(7-4-12-39-34(36)37)31(49)44-27(30(35)48)14-21-16-40-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,40,47H,4,7,12-15H2,1H3,(H2,35,48)(H,38,41)(H,42,46)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.27E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115360
(2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylami...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C36H45N11O5/c1-21(48)44-30(16-25-19-40-20-43-25)33(51)47-36(13-12-22-7-2-3-8-23(22)17-36)34(52)46-28(11-6-14-41-35(38)39)32(50)45-29(31(37)49)15-24-18-42-27-10-5-4-9-26(24)27/h2-5,7-10,18-20,28-30,42H,6,11-17H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,50)(H,46,52)(H,47,51)(H4,38,39,41)/t28-,29-,30-,36?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 263 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115380
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C40H47N11O5/c1-24(52)48-33(20-28-22-44-23-47-28)38(55)51-35(34(25-11-4-2-5-12-25)26-13-6-3-7-14-26)39(56)49-31(17-10-18-45-40(42)43)37(54)50-32(36(41)53)19-27-21-46-30-16-9-8-15-29(27)30/h2-9,11-16,21-23,31-35,46H,10,17-20H2,1H3,(H2,41,53)(H,44,47)(H,48,52)(H,49,56)(H,50,54)(H,51,55)(H4,42,43,45)/t31-,32-,33-,35-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115373
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,26.27,wD:37.38,(23.38,-8.66,;23.38,-10.2,;22.06,-10.96,;24.72,-10.97,;26.05,-10.21,;26.05,-8.66,;27.39,-7.89,;28.79,-8.52,;29.83,-7.38,;29.06,-6.04,;27.55,-6.36,;27.39,-10.97,;27.39,-12.51,;28.72,-10.21,;30.06,-10.97,;30.06,-12.51,;31.39,-13.29,;32.73,-12.51,;34.05,-13.29,;34.05,-14.83,;35.38,-15.6,;32.72,-15.59,;31.39,-14.82,;31.39,-10.21,;31.39,-8.66,;32.72,-10.97,;34.05,-10.2,;34.05,-8.67,;35.38,-7.89,;35.38,-6.36,;36.72,-5.59,;36.72,-4.06,;35.39,-3.28,;38.06,-3.28,;35.38,-10.97,;35.38,-12.52,;36.72,-10.21,;38.06,-10.98,;38.06,-12.52,;39.39,-13.3,;40.8,-12.67,;41.82,-13.82,;41.06,-15.15,;41.52,-16.62,;40.5,-17.76,;38.99,-17.44,;38.51,-15.97,;39.55,-14.83,;39.39,-10.22,;40.73,-10.98,;39.39,-8.68,)| Show InChI InChI=1S/C34H42IN11O5/c1-19(47)43-29(15-23-17-39-18-42-23)33(51)46-28(13-20-8-10-22(35)11-9-20)32(50)44-26(7-4-12-40-34(37)38)31(49)45-27(30(36)48)14-21-16-41-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,41H,4,7,12-15H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28+,29-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 60.4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50115373
(2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r,wU:4.3,14.14,26.27,wD:37.38,(23.38,-8.66,;23.38,-10.2,;22.06,-10.96,;24.72,-10.97,;26.05,-10.21,;26.05,-8.66,;27.39,-7.89,;28.79,-8.52,;29.83,-7.38,;29.06,-6.04,;27.55,-6.36,;27.39,-10.97,;27.39,-12.51,;28.72,-10.21,;30.06,-10.97,;30.06,-12.51,;31.39,-13.29,;32.73,-12.51,;34.05,-13.29,;34.05,-14.83,;35.38,-15.6,;32.72,-15.59,;31.39,-14.82,;31.39,-10.21,;31.39,-8.66,;32.72,-10.97,;34.05,-10.2,;34.05,-8.67,;35.38,-7.89,;35.38,-6.36,;36.72,-5.59,;36.72,-4.06,;35.39,-3.28,;38.06,-3.28,;35.38,-10.97,;35.38,-12.52,;36.72,-10.21,;38.06,-10.98,;38.06,-12.52,;39.39,-13.3,;40.8,-12.67,;41.82,-13.82,;41.06,-15.15,;41.52,-16.62,;40.5,-17.76,;38.99,-17.44,;38.51,-15.97,;39.55,-14.83,;39.39,-10.22,;40.73,-10.98,;39.39,-8.68,)| Show InChI InChI=1S/C34H42IN11O5/c1-19(47)43-29(15-23-17-39-18-42-23)33(51)46-28(13-20-8-10-22(35)11-9-20)32(50)44-26(7-4-12-40-34(37)38)31(49)45-27(30(36)48)14-21-16-41-25-6-3-2-5-24(21)25/h2-3,5-6,8-11,16-18,26-29,41H,4,7,12-15H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28+,29-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-4 receptor (mMC4R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115379
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccnc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C33H42N12O5/c1-19(46)42-28(14-22-17-38-18-41-22)32(50)45-27(12-20-6-4-10-37-15-20)31(49)43-25(9-5-11-39-33(35)36)30(48)44-26(29(34)47)13-21-16-40-24-8-3-2-7-23(21)24/h2-4,6-8,10,15-18,25-28,40H,5,9,11-14H2,1H3,(H2,34,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,35,36,39)/t25-,26-,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50115369
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C33H42N12O5/c1-19(46)42-28(15-22-17-38-18-41-22)32(50)45-27(13-20-8-11-37-12-9-20)31(49)43-25(7-4-10-39-33(35)36)30(48)44-26(29(34)47)14-21-16-40-24-6-3-2-5-23(21)24/h2-3,5-6,8-9,11-12,16-18,25-28,40H,4,7,10,13-15H2,1H3,(H2,34,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,35,36,39)/t25-,26-,27-,28-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity towards mouse Melanocortin-5 receptor (mMC5R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115379
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccnc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C33H42N12O5/c1-19(46)42-28(14-22-17-38-18-41-22)32(50)45-27(12-20-6-4-10-37-15-20)31(49)43-25(9-5-11-39-33(35)36)30(48)44-26(29(34)47)13-21-16-40-24-8-3-2-7-23(21)24/h2-4,6-8,10,15-18,25-28,40H,5,9,11-14H2,1H3,(H2,34,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,35,36,39)/t25-,26-,27-,28-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.29E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50115381
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C40H47N11O5/c1-24(52)48-35(20-29-22-44-23-47-29)39(56)51-34(18-25-13-15-27(16-14-25)26-8-3-2-4-9-26)38(55)49-32(12-7-17-45-40(42)43)37(54)50-33(36(41)53)19-28-21-46-31-11-6-5-10-30(28)31/h2-6,8-11,13-16,21-23,32-35,46H,7,12,17-20H2,1H3,(H2,41,53)(H,44,47)(H,48,52)(H,49,55)(H,50,54)(H,51,56)(H4,42,43,45)/t32-,33-,34+,35-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.05E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50034910
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-3 receptor (mMC3R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50115374
(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Agonist activity to the mouse Melanocortin-1 receptor (mMC1R) |
J Med Chem 45: 3073-81 (2002)
BindingDB Entry DOI: 10.7270/Q2KK9CHF |
More data for this
Ligand-Target Pair | |
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