BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50037159
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50100565 (6-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1A adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50100565 (6-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1D adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50122803 ((SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1D adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50030614 (5-Chloro-8-methyl-1-vinyl-6,7,8,9-tetrahydro-2-thi...) Show SMILES CN1CCc2c(Cl)ccc3sc(C=C)c(C1)c23 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1D adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1D adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50030614 (5-Chloro-8-methyl-1-vinyl-6,7,8,9-tetrahydro-2-thi...) Show SMILES CN1CCc2c(Cl)ccc3sc(C=C)c(C1)c23 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1B adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50130338 ((S)-2,9-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquin...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1D adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50100565 (6-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1B adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50030614 (5-Chloro-8-methyl-1-vinyl-6,7,8,9-tetrahydro-2-thi...) Show SMILES CN1CCc2c(Cl)ccc3sc(C=C)c(C1)c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1A adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50122803 ((SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1B adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1A adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50122803 ((SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	294	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1A adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50100553 (6-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-3-me...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1D adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50130338 ((S)-2,9-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquin...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1B adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50130338 ((S)-2,9-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquin...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	616	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1A adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description In vitro binding affinity at human Alpha-1B adrenergic receptor.				J Med Chem 46: 2877-94 (2003) Article DOI: 10.1021/jm0307741 BindingDB Entry DOI: 10.7270/Q2G73FFQ
Universit£ di Catania Curated by ChEMBL					More data for this Ligand-Target Pair