Compile Data Set for Download or QSAR

Found 170 hits Enz. Inhib. hit(s) with all data for entry = 50037184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM30344 (Cipemastat | Trocade) Show SMILES CN1C(=O)N(C[C@@H]([C@@H](CC2CCCC2)C(=O)N2CCCCC2)C(=O)NO)C(=O)C1(C)C |r| Show InChI InChI=1S/C22H36N4O5/c1-22(2)20(29)26(21(30)24(22)3)14-17(18(27)23-31)16(13-15-9-5-6-10-15)19(28)25-11-7-4-8-12-25/h15-17,31H,4-14H2,1-3H3,(H,23,27)/t16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-1 (MMP1)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) Show SMILES ONC(=O)C(CCn1nnc2ccccc2c1=O)CSc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN4O3S/c25-19-9-5-16(6-10-19)17-7-11-20(12-8-17)33-15-18(23(30)27-32)13-14-29-24(31)21-3-1-2-4-22(21)26-28-29/h1-12,18,32H,13-15H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) Show SMILES CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) Show SMILES ONC(=O)C(CCn1nnc2ccccc2c1=O)CSc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN4O3S/c25-19-9-5-16(6-10-19)17-7-11-20(12-8-17)33-15-18(23(30)27-32)13-14-29-24(31)21-3-1-2-4-22(21)26-28-29/h1-12,18,32H,13-15H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) Show SMILES CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) Show SMILES CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) Show SMILES ONC(=O)C(CCn1nnc2ccccc2c1=O)CSc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN4O3S/c25-19-9-5-16(6-10-19)17-7-11-20(12-8-17)33-15-18(23(30)27-32)13-14-29-24(31)21-3-1-2-4-22(21)26-28-29/h1-12,18,32H,13-15H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131944 (2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-(...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C25H22N4O3S/c30-24-20-3-1-2-4-21(20)27-28-29(24)15-18-7-10-22(23(18)25(31)32)33-19-8-5-16(6-9-19)17-11-13-26-14-12-17/h1-6,8-9,11-14,18,22-23H,7,10,15H2,(H,31,32)/t18-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) Show SMILES CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r| Show InChI InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-1 (MMP1)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r| Show InChI InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131964 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(3-oxo-6,7,8...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nc3CCCCCn3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28ClN3O3S/c27-20-10-5-17(6-11-20)18-7-12-21(13-8-18)34-22-14-9-19(24(22)25(31)32)16-30-26(33)29-15-3-1-2-4-23(29)28-30/h5-8,10-13,19,22,24H,1-4,9,14-16H2,(H,31,32)/t19-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r| Show InChI InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131962 (2-(4'-Chloro-biphenyl-4-sulfonyl)-5-(4-oxo-4H-benz...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1S(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O5S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)36(34,35)23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131953 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@@H]1[C@@H](Cn2nnc3ccccc3c2=O)CC[C@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131958 (2-[2-(4'-Chloro-biphenyl-4-yl)-ethanesulfonyl]-5-(...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1S(=O)(=O)CCc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H26ClN3O5S/c29-22-12-9-20(10-13-22)19-7-5-18(6-8-19)15-16-38(36,37)25-14-11-21(26(25)28(34)35)17-32-27(33)23-3-1-2-4-24(23)30-31-32/h1-10,12-13,21,25-26H,11,14-17H2,(H,34,35)/t21-,25-,26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131952 (2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...) Show SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H25NO4S/c30-26-22-8-4-5-9-23(22)27(31)29(26)16-21-14-15-24(25(21)28(32)33)34-17-18-10-12-20(13-11-18)19-6-2-1-3-7-19/h1-13,21,24-25H,14-17H2,(H,32,33)/t21-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131937 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131937 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131952 (2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...) Show SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H25NO4S/c30-26-22-8-4-5-9-23(22)27(31)29(26)16-21-14-15-24(25(21)28(32)33)34-17-18-10-12-20(13-11-18)19-6-2-1-3-7-19/h1-13,21,24-25H,14-17H2,(H,32,33)/t21-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131953 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@@H]1[C@@H](Cn2nnc3ccccc3c2=O)CC[C@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131949 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...) Show SMILES CC1(C)NC(=O)N(C[C@@H]2CC[C@H](Sc3ccc(cc3)-c3ccc(Cl)cc3)[C@H]2C(O)=O)C1=O Show InChI InChI=1S/C24H25ClN2O4S/c1-24(2)22(30)27(23(31)26-24)13-16-7-12-19(20(16)21(28)29)32-18-10-5-15(6-11-18)14-3-8-17(25)9-4-14/h3-6,8-11,16,19-20H,7,12-13H2,1-2H3,(H,26,31)(H,28,29)/t16-,19-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131949 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...) Show SMILES CC1(C)NC(=O)N(C[C@@H]2CC[C@H](Sc3ccc(cc3)-c3ccc(Cl)cc3)[C@H]2C(O)=O)C1=O Show InChI InChI=1S/C24H25ClN2O4S/c1-24(2)22(30)27(23(31)26-24)13-16-7-12-19(20(16)21(28)29)32-18-10-5-15(6-11-18)14-3-8-17(25)9-4-14/h3-6,8-11,16,19-20H,7,12-13H2,1-2H3,(H,26,31)(H,28,29)/t16-,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131937 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131937 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM30344 (Cipemastat | Trocade) Show SMILES CN1C(=O)N(C[C@@H]([C@@H](CC2CCCC2)C(=O)N2CCCCC2)C(=O)NO)C(=O)C1(C)C |r| Show InChI InChI=1S/C22H36N4O5/c1-22(2)20(29)26(21(30)24(22)3)14-17(18(27)23-31)16(13-15-9-5-6-10-15)19(28)25-11-7-4-8-12-25/h15-17,31H,4-14H2,1-3H3,(H,23,27)/t16-,17+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r| Show InChI InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131952 (2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...) Show SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H25NO4S/c30-26-22-8-4-5-9-23(22)27(31)29(26)16-21-14-15-24(25(21)28(32)33)34-17-18-10-12-20(13-11-18)19-6-2-1-3-7-19/h1-13,21,24-25H,14-17H2,(H,32,33)/t21-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131964 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(3-oxo-6,7,8...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nc3CCCCCn3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28ClN3O3S/c27-20-10-5-17(6-11-20)18-7-12-21(13-8-18)34-22-14-9-19(24(22)25(31)32)16-30-26(33)29-15-3-1-2-4-23(29)28-30/h5-8,10-13,19,22,24H,1-4,9,14-16H2,(H,31,32)/t19-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131960 (2-(4'-Methylsulfanyl-biphenyl-4-ylsulfanyl)-5-(4-o...) Show SMILES CSc1ccc(cc1)-c1ccc(S[C@H]2CC[C@@H](Cn3nnc4ccccc4c3=O)[C@@H]2C(O)=O)cc1 Show InChI InChI=1S/C27H25N3O3S2/c1-34-20-11-6-17(7-12-20)18-8-13-21(14-9-18)35-24-15-10-19(25(24)27(32)33)16-30-26(31)22-4-2-3-5-23(22)28-29-30/h2-9,11-14,19,24-25H,10,15-16H2,1H3,(H,32,33)/t19-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131937 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131960 (2-(4'-Methylsulfanyl-biphenyl-4-ylsulfanyl)-5-(4-o...) Show SMILES CSc1ccc(cc1)-c1ccc(S[C@H]2CC[C@@H](Cn3nnc4ccccc4c3=O)[C@@H]2C(O)=O)cc1 Show InChI InChI=1S/C27H25N3O3S2/c1-34-20-11-6-17(7-12-20)18-8-13-21(14-9-18)35-24-15-10-19(25(24)27(32)33)16-30-26(31)22-4-2-3-5-23(22)28-29-30/h2-9,11-14,19,24-25H,10,15-16H2,1H3,(H,32,33)/t19-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131947 (2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H22N4O3S/c28-15-17-5-7-18(8-6-17)19-9-12-21(13-10-19)35-24-14-11-20(25(24)27(33)34)16-31-26(32)22-3-1-2-4-23(22)29-30-31/h1-10,12-13,20,24-25H,11,14,16H2,(H,33,34)/t20-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131937 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131964 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(3-oxo-6,7,8...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nc3CCCCCn3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28ClN3O3S/c27-20-10-5-17(6-11-20)18-7-12-21(13-8-18)34-22-14-9-19(24(22)25(31)32)16-30-26(33)29-15-3-1-2-4-23(29)28-30/h5-8,10-13,19,22,24H,1-4,9,14-16H2,(H,31,32)/t19-,22-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131953 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) Show SMILES OC(=O)[C@@H]1[C@@H](Cn2nnc3ccccc3c2=O)CC[C@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O3S/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-23-14-9-18(24(23)26(32)33)15-30-25(31)21-3-1-2-4-22(21)28-29-30/h1-8,10-13,18,23-24H,9,14-15H2,(H,32,33)/t18-,23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131951 (2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-(...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1nccs1 Show InChI InChI=1S/C23H20N4O3S2/c28-22-17-3-1-2-4-18(17)25-26-27(22)13-15-7-10-19(20(15)23(29)30)32-16-8-5-14(6-9-16)21-24-11-12-31-21/h1-6,8-9,11-12,15,19-20H,7,10,13H2,(H,29,30)/t15-,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131951 (2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-(...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1nccs1 Show InChI InChI=1S/C23H20N4O3S2/c28-22-17-3-1-2-4-18(17)25-26-27(22)13-15-7-10-19(20(15)23(29)30)32-16-8-5-14(6-9-16)21-24-11-12-31-21/h1-6,8-9,11-12,15,19-20H,7,10,13H2,(H,29,30)/t15-,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131959 (2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C27H22N4O3S2/c32-26-19-5-1-2-6-20(19)29-30-31(26)15-17-11-14-23(24(17)27(33)34)35-18-12-9-16(10-13-18)25-28-21-7-3-4-8-22(21)36-25/h1-10,12-13,17,23-24H,11,14-15H2,(H,33,34)/t17-,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131942 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(2,4-dioxo-2...) Show SMILES OC(=O)[C@H]1[C@H](Cn2c(=O)nc3ccccn3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN3O4S/c27-19-9-4-16(5-10-19)17-6-11-20(12-7-17)35-21-13-8-18(23(21)24(31)32)15-30-25(33)28-22-3-1-2-14-29(22)26(30)34/h1-7,9-12,14,18,21,23H,8,13,15H2,(H,31,32)/t18-,21-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131949 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4,4-dimethy...) Show SMILES CC1(C)NC(=O)N(C[C@@H]2CC[C@H](Sc3ccc(cc3)-c3ccc(Cl)cc3)[C@H]2C(O)=O)C1=O Show InChI InChI=1S/C24H25ClN2O4S/c1-24(2)22(30)27(23(31)26-24)13-16-7-12-19(20(16)21(28)29)32-18-10-5-15(6-11-18)14-3-8-17(25)9-4-14/h3-6,8-11,16,19-20H,7,12-13H2,1-2H3,(H,26,31)(H,28,29)/t16-,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) Show SMILES ONC(=O)C(CCn1nnc2ccccc2c1=O)CSc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN4O3S/c25-19-9-5-16(6-10-19)17-7-11-20(12-8-17)33-15-18(23(30)27-32)13-14-29-24(31)21-3-1-2-4-22(21)26-28-29/h1-12,18,32H,13-15H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131947 (2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H22N4O3S/c28-15-17-5-7-18(8-6-17)19-9-12-21(13-10-19)35-24-14-11-20(25(24)27(33)34)16-31-26(32)22-3-1-2-4-23(22)29-30-31/h1-10,12-13,20,24-25H,11,14,16H2,(H,33,34)/t20-,24-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131957 (2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3...) Show SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C29H27NO4S/c31-27-23-8-4-5-9-24(23)28(32)30(27)18-22-14-15-25(26(22)29(33)34)35-17-16-19-10-12-21(13-11-19)20-6-2-1-3-7-20/h1-13,22,25-26H,14-18H2,(H,33,34)/t22-,25-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131940 (2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1...) Show SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCCc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C29H26ClNO4S/c30-22-12-9-20(10-13-22)19-7-5-18(6-8-19)15-16-36-25-14-11-21(26(25)29(34)35)17-31-27(32)23-3-1-2-4-24(23)28(31)33/h1-10,12-13,21,25-26H,11,14-17H2,(H,34,35)/t21-,25-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131947 (2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...) Show SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H22N4O3S/c28-15-17-5-7-18(8-6-17)19-9-12-21(13-10-19)35-24-14-11-20(25(24)27(33)34)16-31-26(32)22-3-1-2-4-23(22)29-30-31/h1-10,12-13,20,24-25H,11,14,16H2,(H,33,34)/t20-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131960 (2-(4'-Methylsulfanyl-biphenyl-4-ylsulfanyl)-5-(4-o...) Show SMILES CSc1ccc(cc1)-c1ccc(S[C@H]2CC[C@@H](Cn3nnc4ccccc4c3=O)[C@@H]2C(O)=O)cc1 Show InChI InChI=1S/C27H25N3O3S2/c1-34-20-11-6-17(7-12-20)18-8-13-21(14-9-18)35-24-15-10-19(25(24)27(32)33)16-30-26(31)22-4-2-3-5-23(22)28-29-30/h2-9,11-14,19,24-25H,10,15-16H2,1H3,(H,32,33)/t19-,24-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50131943 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(1,1,3-triox...) Show SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3S2(=O)=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClNO5S2/c27-19-10-5-16(6-11-19)17-7-12-20(13-8-17)34-22-14-9-18(24(22)26(30)31)15-28-25(29)21-3-1-2-4-23(21)35(28,32)33/h1-8,10-13,18,22,24H,9,14-15H2,(H,30,31)/t18-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2)				J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF
					More data for this Ligand-Target Pair

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