Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27826 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 9 | 4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27825 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 8 | 4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27842 (4,5-difluoro-2-{[2-({2-methoxy-4-[4-(propan-2-yl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27822 (2-[(2-{[2-methoxy-4-(1-propyl-1,2,5,6-tetrahydropy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27823 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 6 | 4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27841 (2,4-difluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27839 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 25 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27828 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 11 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27838 (2-{[2-({2-methoxy-4-[4-(propan-2-yl)piperazin-1-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27840 (2,3-difluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27819 (2-[(2-{[4-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27827 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 10 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27829 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 12 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27835 (2-{[2-({5-chloro-2-methoxy-4-[4-(propan-2-yl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27820 (2-[(2-{[2-fluoro-4-(1-propyl-1,2,5,6-tetrahydropyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27783 (2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27833 (2-fluoro-6-{[2-({5-fluoro-2-methoxy-4-[4-(propan-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27834 (2-fluoro-6-{[2-({2-methoxy-5-methyl-4-[4-(propan-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27832 (2-{[2-({2,5-dimethoxy-4-[4-(propan-2-yl)piperazin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27844 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 30 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27824 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 7 | 4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27784 (2-fluoro-6-{[2-({2-methoxy-5-[4-(propan-2-yl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27836 (2-fluoro-6-{[2-({3-fluoro-2-methoxy-4-[4-(propan-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27843 (2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27847 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 33 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27818 (2-[(2-{[2-methyl-4-(1-propyl-1,2,5,6-tetrahydropyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27845 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 31 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27837 (2-fluoro-6-{[2-({2-methoxy-3-methyl-4-[4-(propan-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27846 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 32 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27821 (2-[(2-{[4-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27785 (2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27848 (4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 34 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27830 (2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM27831 (2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th... | Bioorg Med Chem Lett 19: 469-73 (2009) Article DOI: 10.1016/j.bmcl.2008.11.046 BindingDB Entry DOI: 10.7270/Q2J67F88 | |||||||||||
More data for this Ligand-Target Pair |