Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50038045 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222831
(CHEMBL401132 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(c2Cl)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22ClF3N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-8-9-12)25-17(27)13-6-5-7-14(15(13)21)20(22,23)24/h5-7,12H,8-10H2,1-4H3/b25-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222845
(CHEMBL247830 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2ccccc2C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2OS/c1-12-16(19(2,3)4)27-18(25(12)11-13-9-10-13)24-17(26)14-7-5-6-8-15(14)20(21,22)23/h5-8,13H,9-11H2,1-4H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072775
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r| Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222834
(CHEMBL398713 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES COc1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C21H25F3N2O2S/c1-12-17(20(2,3)4)29-19(26(12)11-13-6-7-13)25-18(27)15-10-14(21(22,23)24)8-9-16(15)28-5/h8-10,13H,6-7,11H2,1-5H3/b25-19- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222841
((Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(Br)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H23BrN2OS/c1-12-16(19(2,3)4)24-18(22(12)11-13-8-9-13)21-17(23)14-6-5-7-15(20)10-14/h5-7,10,13H,8-9,11H2,1-4H3/b21-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50072775
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r| Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222832
(CHEMBL248386 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(sc(=NC(=O)c2cc(ccc2C)C(F)(F)F)n1CC1CC1)C(C)(C)C |w:5.5| Show InChI InChI=1S/C21H25F3N2OS/c1-12-6-9-15(21(22,23)24)10-16(12)18(27)25-19-26(11-14-7-8-14)13(2)17(28-19)20(3,4)5/h6,9-10,14H,7-8,11H2,1-5H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222833
(CHEMBL555610 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cc(ccc2Cl)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22ClF3N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)14-9-13(20(22,23)24)7-8-15(14)21/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222844
(CHEMBL248015 | N-(5-tert-butyl-3-(2-ethoxyethyl)-4...)Show SMILES CCOCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C20H25F3N2O2S/c1-6-27-11-10-25-13(2)16(19(3,4)5)28-18(25)24-17(26)14-8-7-9-15(12-14)20(21,22)23/h7-9,12H,6,10-11H2,1-5H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222837
(CHEMBL248385 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cc(ccc2F)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22F4N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)14-9-13(20(22,23)24)7-8-15(14)21/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222836
(CHEMBL247651 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(OC(F)(F)F)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2O2S/c1-12-16(19(2,3)4)28-18(25(12)11-13-8-9-13)24-17(26)14-6-5-7-15(10-14)27-20(21,22)23/h5-7,10,13H,8-9,11H2,1-4H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222835
(CHEMBL248387 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES CN(C)c1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C22H28F3N3OS/c1-13-18(21(2,3)4)30-20(28(13)12-14-7-8-14)26-19(29)16-11-15(22(23,24)25)9-10-17(16)27(5)6/h9-11,14H,7-8,12H2,1-6H3/b26-20- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222830
(CHEMBL248014 | N-(5-tert-butyl-3-(2-methoxyethyl)-...)Show SMILES COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2O2S/c1-12-15(18(2,3)4)27-17(24(12)9-10-26-5)23-16(25)13-7-6-8-14(11-13)19(20,21)22/h6-8,11H,9-10H2,1-5H3/b23-17- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222843
(CHEMBL398666 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2OS/c1-12-16(19(2,3)4)27-18(25(12)11-13-8-9-13)24-17(26)14-6-5-7-15(10-14)20(21,22)23/h5-7,10,13H,8-9,11H2,1-4H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222829
(CHEMBL395216 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES CN(C)c1cccc(c1)C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C21H29N3OS/c1-14-18(21(2,3)4)26-20(24(14)13-15-10-11-15)22-19(25)16-8-7-9-17(12-16)23(5)6/h7-9,12,15H,10-11,13H2,1-6H3/b22-20- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222831
(CHEMBL401132 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(c2Cl)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22ClF3N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-8-9-12)25-17(27)13-6-5-7-14(15(13)21)20(22,23)24/h5-7,12H,8-10H2,1-4H3/b25-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222842
(CHEMBL247817 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(Cl)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H23ClN2OS/c1-12-16(19(2,3)4)24-18(22(12)11-13-8-9-13)21-17(23)14-6-5-7-15(20)10-14/h5-7,10,13H,8-9,11H2,1-4H3/b21-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222847
(CHEMBL397857 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(C)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H26N2OS/c1-13-7-6-8-16(11-13)18(23)21-19-22(12-15-9-10-15)14(2)17(24-19)20(3,4)5/h6-8,11,15H,9-10,12H2,1-5H3/b21-19- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222849
(CHEMBL247997 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES COc1cccc(c1)C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H26N2O2S/c1-13-17(20(2,3)4)25-19(22(13)12-14-9-10-14)21-18(23)15-7-6-8-16(11-15)24-5/h6-8,11,14H,9-10,12H2,1-5H3/b21-19- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222848
(CHEMBL399912 | N-(3-(cyclopropylmethyl)-4,5-dimeth...)Show SMILES Cc1s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n(CC2CC2)c1C Show InChI InChI=1S/C17H17F3N2OS/c1-10-11(2)24-16(22(10)9-12-6-7-12)21-15(23)13-4-3-5-14(8-13)17(18,19)20/h3-5,8,12H,6-7,9H2,1-2H3/b21-16- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222851
(CHEMBL400931 | N-(3-(cyclopropylmethyl)-5-isopropy...)Show SMILES CC(C)c1s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n(CC2CC2)c1C Show InChI InChI=1S/C19H21F3N2OS/c1-11(2)16-12(3)24(10-13-7-8-13)18(26-16)23-17(25)14-5-4-6-15(9-14)19(20,21)22/h4-6,9,11,13H,7-8,10H2,1-3H3/b23-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222850
(CHEMBL399911 | N-(5-tert-butyl-4-methyl-3-propylth...)Show SMILES CCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2OS/c1-6-10-24-12(2)15(18(3,4)5)26-17(24)23-16(25)13-8-7-9-14(11-13)19(20,21)22/h7-9,11H,6,10H2,1-5H3/b23-17- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222841
((Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(Br)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H23BrN2OS/c1-12-16(19(2,3)4)24-18(22(12)11-13-8-9-13)21-17(23)14-6-5-7-15(20)10-14/h5-7,10,13H,8-9,11H2,1-4H3/b21-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222846
(CHEMBL248013 | N-(5-tert-butyl-3-ethyl-4-methylthi...)Show SMILES CCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C18H21F3N2OS/c1-6-23-11(2)14(17(3,4)5)25-16(23)22-15(24)12-8-7-9-13(10-12)18(19,20)21/h7-10H,6H2,1-5H3/b22-16- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222838
(CHEMBL248201 | ethyl 3-(cyclopropylmethyl)-4-methy...)Show SMILES CCOC(=O)c1s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n(CC2CC2)c1C Show InChI InChI=1S/C19H19F3N2O3S/c1-3-27-17(26)15-11(2)24(10-12-7-8-12)18(28-15)23-16(25)13-5-4-6-14(9-13)19(20,21)22/h4-6,9,12H,3,7-8,10H2,1-2H3/b23-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222845
(CHEMBL247830 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2ccccc2C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2OS/c1-12-16(19(2,3)4)27-18(25(12)11-13-9-10-13)24-17(26)14-7-5-6-8-15(14)20(21,22)23/h5-8,13H,9-11H2,1-4H3/b24-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222828
(CHEMBL247832 | N-(5-tert-butyl-3,4-dimethylthiazol...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n1C)C(C)(C)C Show InChI InChI=1S/C17H19F3N2OS/c1-10-13(16(2,3)4)24-15(22(10)5)21-14(23)11-7-6-8-12(9-11)17(18,19)20/h6-9H,1-5H3/b21-15- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222852
(CHEMBL248203 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2ccc(Cl)c(c2)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22ClF3N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)13-7-8-15(21)14(9-13)20(22,23)24/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222839
(CHEMBL395704 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2ccccc2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H24N2OS/c1-13-16(19(2,3)4)23-18(21(13)12-14-10-11-14)20-17(22)15-8-6-5-7-9-15/h5-9,14H,10-12H2,1-4H3/b20-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222844
(CHEMBL248015 | N-(5-tert-butyl-3-(2-ethoxyethyl)-4...)Show SMILES CCOCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C20H25F3N2O2S/c1-6-27-11-10-25-13(2)16(19(3,4)5)28-18(25)24-17(26)14-8-7-9-15(12-14)20(21,22)23/h7-9,12H,6,10-11H2,1-5H3/b24-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222833
(CHEMBL555610 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cc(ccc2Cl)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22ClF3N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)14-9-13(20(22,23)24)7-8-15(14)21/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222840
(3-(cyclopropylmethyl)-N,N,4-trimethyl-2-(3-(triflu...)Show SMILES CN(C)C(=O)c1s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n(CC2CC2)c1C Show InChI InChI=1S/C19H20F3N3O2S/c1-11-15(17(27)24(2)3)28-18(25(11)10-12-7-8-12)23-16(26)13-5-4-6-14(9-13)19(20,21)22/h4-6,9,12H,7-8,10H2,1-3H3/b23-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222836
(CHEMBL247651 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(OC(F)(F)F)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2O2S/c1-12-16(19(2,3)4)28-18(25(12)11-13-8-9-13)24-17(26)14-6-5-7-15(10-14)27-20(21,22)23/h5-7,10,13H,8-9,11H2,1-4H3/b24-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222832
(CHEMBL248386 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(sc(=NC(=O)c2cc(ccc2C)C(F)(F)F)n1CC1CC1)C(C)(C)C |w:5.5| Show InChI InChI=1S/C21H25F3N2OS/c1-12-6-9-15(21(22,23)24)10-16(12)18(27)25-19-26(11-14-7-8-14)13(2)17(28-19)20(3,4)5/h6,9-10,14H,7-8,11H2,1-5H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222837
(CHEMBL248385 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cc(ccc2F)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22F4N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)14-9-13(20(22,23)24)7-8-15(14)21/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222834
(CHEMBL398713 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES COc1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C21H25F3N2O2S/c1-12-17(20(2,3)4)29-19(26(12)11-13-6-7-13)25-18(27)15-10-14(21(22,23)24)8-9-16(15)28-5/h8-10,13H,6-7,11H2,1-5H3/b25-19- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222843
(CHEMBL398666 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2OS/c1-12-16(19(2,3)4)27-18(25(12)11-13-8-9-13)24-17(26)14-6-5-7-15(10-14)20(21,22)23/h5-7,10,13H,8-9,11H2,1-4H3/b24-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222830
(CHEMBL248014 | N-(5-tert-butyl-3-(2-methoxyethyl)-...)Show SMILES COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2O2S/c1-12-15(18(2,3)4)27-17(24(12)9-10-26-5)23-16(25)13-7-6-8-14(11-13)19(20,21)22/h6-8,11H,9-10H2,1-5H3/b23-17- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50222835
(CHEMBL248387 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES CN(C)c1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C22H28F3N3OS/c1-13-18(21(2,3)4)30-20(28(13)12-14-7-8-14)26-19(29)16-11-15(22(23,24)25)9-10-17(16)27(5)6/h9-11,14H,7-8,12H2,1-6H3/b26-20- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222833
(CHEMBL555610 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cc(ccc2Cl)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22ClF3N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)14-9-13(20(22,23)24)7-8-15(14)21/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222841
((Z)-3-bromo-N-(5-tert-butyl-3-(cyclopropylmethyl)-...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(Br)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H23BrN2OS/c1-12-16(19(2,3)4)24-18(22(12)11-13-8-9-13)21-17(23)14-6-5-7-15(20)10-14/h5-7,10,13H,8-9,11H2,1-4H3/b21-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222843
(CHEMBL398666 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2OS/c1-12-16(19(2,3)4)27-18(25(12)11-13-8-9-13)24-17(26)14-6-5-7-15(10-14)20(21,22)23/h5-7,10,13H,8-9,11H2,1-4H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222844
(CHEMBL248015 | N-(5-tert-butyl-3-(2-ethoxyethyl)-4...)Show SMILES CCOCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C20H25F3N2O2S/c1-6-27-11-10-25-13(2)16(19(3,4)5)28-18(25)24-17(26)14-8-7-9-15(12-14)20(21,22)23/h7-9,12H,6,10-11H2,1-5H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222834
(CHEMBL398713 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES COc1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C21H25F3N2O2S/c1-12-17(20(2,3)4)29-19(26(12)11-13-6-7-13)25-18(27)15-10-14(21(22,23)24)8-9-16(15)28-5/h8-10,13H,6-7,11H2,1-5H3/b25-19- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222832
(CHEMBL248386 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(sc(=NC(=O)c2cc(ccc2C)C(F)(F)F)n1CC1CC1)C(C)(C)C |w:5.5| Show InChI InChI=1S/C21H25F3N2OS/c1-12-6-9-15(21(22,23)24)10-16(12)18(27)25-19-26(11-14-7-8-14)13(2)17(28-19)20(3,4)5/h6,9-10,14H,7-8,11H2,1-5H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222836
(CHEMBL247651 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cccc(OC(F)(F)F)c2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H23F3N2O2S/c1-12-16(19(2,3)4)28-18(25(12)11-13-8-9-13)24-17(26)14-6-5-7-15(10-14)27-20(21,22)23/h5-7,10,13H,8-9,11H2,1-4H3/b24-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222839
(CHEMBL395704 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2ccccc2)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H24N2OS/c1-13-16(19(2,3)4)23-18(21(13)12-14-10-11-14)20-17(22)15-8-6-5-7-9-15/h5-9,14H,10-12H2,1-4H3/b20-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 86 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222830
(CHEMBL248014 | N-(5-tert-butyl-3-(2-methoxyethyl)-...)Show SMILES COCCn1c(C)c(s\c1=N/C(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C19H23F3N2O2S/c1-12-15(18(2,3)4)27-17(24(12)9-10-26-5)23-16(25)13-7-6-8-14(11-13)19(20,21)22/h6-8,11H,9-10H2,1-5H3/b23-17- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222837
(CHEMBL248385 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES Cc1c(s\c(=N/C(=O)c2cc(ccc2F)C(F)(F)F)n1CC1CC1)C(C)(C)C Show InChI InChI=1S/C20H22F4N2OS/c1-11-16(19(2,3)4)28-18(26(11)10-12-5-6-12)25-17(27)14-9-13(20(22,23)24)7-8-15(14)21/h7-9,12H,5-6,10H2,1-4H3/b25-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50222835
(CHEMBL248387 | N-(5-tert-butyl-3-(cyclopropylmethy...)Show SMILES CN(C)c1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C22H28F3N3OS/c1-13-18(21(2,3)4)30-20(28(13)12-14-7-8-14)26-19(29)16-11-15(22(23,24)25)9-10-17(16)27(5)6/h9-11,14H,7-8,12H2,1-6H3/b26-20- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co. Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 17: 6299-304 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.004
BindingDB Entry DOI: 10.7270/Q2PG1SJQ |
More data for this
Ligand-Target Pair | |
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