Compile Data Set for Download or QSAR

Found 128 hits Enz. Inhib. hit(s) with all data for entry = 50038190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372966 (CHEMBL270668) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1 |c:12| Show InChI InChI=1S/C27H30FN3O4S/c1-20-3-9-25(10-4-20)36(32,33)30-12-11-22-15-26-21(16-27(22,18-30)19-35-14-13-34-2)17-29-31(26)24-7-5-23(28)6-8-24/h3-10,15,17H,11-14,16,18-19H2,1-2H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372975 (CHEMBL270667) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1 |c:12| Show InChI InChI=1S/C26H28FN3O4S/c1-33-13-14-34-19-26-16-20-17-28-30(23-9-7-22(27)8-10-23)25(20)15-21(26)11-12-29(18-26)35(31,32)24-5-3-2-4-6-24/h2-10,15,17H,11-14,16,18-19H2,1H3/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372977 (CHEMBL255369) Show SMILES COC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1 |c:9| Show InChI InChI=1S/C25H26FN3O3S/c1-18-3-9-23(10-4-18)33(30,31)28-12-11-20-13-24-19(14-25(20,16-28)17-32-2)15-27-29(24)22-7-5-21(26)6-8-22/h3-10,13,15H,11-12,14,16-17H2,1-2H3/t25-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372965 (CHEMBL442803) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1 |c:12| Show InChI InChI=1S/C26H27F2N3O4S/c1-34-12-13-35-18-26-15-19-16-29-31(23-6-2-21(27)3-7-23)25(19)14-20(26)10-11-30(17-26)36(32,33)24-8-4-22(28)5-9-24/h2-9,14,16H,10-13,15,17-18H2,1H3/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372974 (CHEMBL270575) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:12| Show InChI InChI=1S/C30H36FN3O4S/c1-29(2,3)23-5-11-27(12-6-23)39(35,36)33-14-13-24-17-28-22(18-30(24,20-33)21-38-16-15-37-4)19-32-34(28)26-9-7-25(31)8-10-26/h5-12,17,19H,13-16,18,20-21H2,1-4H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372937 (CHEMBL257461) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@]3(CN4CCOCC4)CN(CCC3=Cc12)S(=O)(=O)c1ccccc1 |c:27| Show InChI InChI=1S/C27H29FN4O3S/c28-23-6-8-24(9-7-23)32-26-16-22-10-11-31(36(33,34)25-4-2-1-3-5-25)20-27(22,17-21(26)18-29-32)19-30-12-14-35-15-13-30/h1-9,16,18H,10-15,17,19-20H2/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372974 (CHEMBL270575) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:12| Show InChI InChI=1S/C30H36FN3O4S/c1-29(2,3)23-5-11-27(12-6-23)39(35,36)33-14-13-24-17-28-22(18-30(24,20-33)21-38-16-15-37-4)19-32-34(28)26-9-7-25(31)8-10-26/h5-12,17,19H,13-16,18,20-21H2,1-4H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372964 (CHEMBL270568) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(COCCO)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C29H34FN3O4S/c1-28(2,3)22-4-10-26(11-5-22)38(35,36)32-13-12-23-16-27-21(17-29(23,19-32)20-37-15-14-34)18-31-33(27)25-8-6-24(30)7-9-25/h4-11,16,18,34H,12-15,17,19-20H2,1-3H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372976 (CHEMBL271221) Show SMILES CCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:10| Show InChI InChI=1S/C29H34FN3O3S/c1-5-36-20-29-17-21-18-31-33(25-10-8-24(30)9-11-25)27(21)16-23(29)14-15-32(19-29)37(34,35)26-12-6-22(7-13-26)28(2,3)4/h6-13,16,18H,5,14-15,17,19-20H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372945 (CHEMBL404183) Show SMILES COCCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:13| Show InChI InChI=1S/C31H38FN3O4S/c1-30(2,3)24-6-12-28(13-7-24)40(36,37)34-15-14-25-18-29-23(19-31(25,21-34)22-39-17-5-16-38-4)20-33-35(29)27-10-8-26(32)9-11-27/h6-13,18,20H,5,14-17,19,21-22H2,1-4H3/t31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372969 (CHEMBL271428) Show SMILES COC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(F)(F)F |c:9| Show InChI InChI=1S/C25H23F4N3O3S/c1-35-16-24-13-17-14-30-32(21-6-4-20(26)5-7-21)23(17)12-19(24)10-11-31(15-24)36(33,34)22-8-2-18(3-9-22)25(27,28)29/h2-9,12,14H,10-11,13,15-16H2,1H3/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372926 (CHEMBL411852) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(COCCC#N)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C30H33FN4O3S/c1-29(2,3)23-5-11-27(12-6-23)39(36,37)34-15-13-24-17-28-22(18-30(24,20-34)21-38-16-4-14-32)19-33-35(28)26-9-7-25(31)8-10-26/h5-12,17,19H,4,13,15-16,18,20-21H2,1-3H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372970 (CHEMBL402893) Show SMILES COC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:9| Show InChI InChI=1S/C28H32FN3O3S/c1-27(2,3)21-5-11-25(12-6-21)36(33,34)31-14-13-22-15-26-20(16-28(22,18-31)19-35-4)17-30-32(26)24-9-7-23(29)8-10-24/h5-12,15,17H,13-14,16,18-19H2,1-4H3/t28-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372931 (CHEMBL409835) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@]3(CN4CCCCC4)CN(CCC3=Cc12)S(=O)(=O)c1ccccc1 |c:27| Show InChI InChI=1S/C28H31FN4O2S/c29-24-9-11-25(12-10-24)33-27-17-23-13-16-32(36(34,35)26-7-3-1-4-8-26)21-28(23,18-22(27)19-30-33)20-31-14-5-2-6-15-31/h1,3-4,7-12,17,19H,2,5-6,13-16,18,20-21H2/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372929 (CHEMBL270838) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CN2CCOCC2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C31H37FN4O3S/c1-30(2,3)24-4-10-28(11-5-24)40(37,38)35-13-12-25-18-29-23(20-33-36(29)27-8-6-26(32)7-9-27)19-31(25,22-35)21-34-14-16-39-17-15-34/h4-11,18,20H,12-17,19,21-22H2,1-3H3/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372918 (CHEMBL401864) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CNCC=C)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C30H35FN4O2S/c1-5-15-32-20-30-18-22-19-33-35(26-10-8-25(31)9-11-26)28(22)17-24(30)14-16-34(21-30)38(36,37)27-12-6-23(7-13-27)29(2,3)4/h5-13,17,19,32H,1,14-16,18,20-21H2,2-4H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372968 (CHEMBL271220) Show SMILES CCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(F)(F)F |c:10| Show InChI InChI=1S/C26H25F4N3O3S/c1-2-36-17-25-14-18-15-31-33(22-7-5-21(27)6-8-22)24(18)13-20(25)11-12-32(16-25)37(34,35)23-9-3-19(4-10-23)26(28,29)30/h3-10,13,15H,2,11-12,14,16-17H2,1H3/t25-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372967 (CHEMBL270879) Show SMILES CCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(F)(F)F |c:11| Show InChI InChI=1S/C27H27F4N3O3S/c1-2-13-37-18-26-15-19-16-32-34(23-7-5-22(28)6-8-23)25(19)14-21(26)11-12-33(17-26)38(35,36)24-9-3-20(4-10-24)27(29,30)31/h3-10,14,16H,2,11-13,15,17-18H2,1H3/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372921 (CHEMBL270143) Show SMILES COCCNC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:12| Show InChI InChI=1S/C30H37FN4O3S/c1-29(2,3)23-5-11-27(12-6-23)39(36,37)34-15-13-24-17-28-22(18-30(24,21-34)20-32-14-16-38-4)19-33-35(28)26-9-7-25(31)8-10-26/h5-12,17,19,32H,13-16,18,20-21H2,1-4H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372972 (CHEMBL403172) Show SMILES COC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1 |c:9| Show InChI InChI=1S/C24H24FN3O3S/c1-31-17-24-14-18-15-26-28(21-9-7-20(25)8-10-21)23(18)13-19(24)11-12-27(16-24)32(29,30)22-5-3-2-4-6-22/h2-10,13,15H,11-12,14,16-17H2,1H3/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372936 (CHEMBL257203) Show SMILES CN(C)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1 |c:10| Show InChI InChI=1S/C25H27FN4O2S/c1-28(2)17-25-15-19-16-27-30(22-10-8-21(26)9-11-22)24(19)14-20(25)12-13-29(18-25)33(31,32)23-6-4-3-5-7-23/h3-11,14,16H,12-13,15,17-18H2,1-2H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372938 (CHEMBL429913) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CN2CCCC2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C31H37FN4O2S/c1-30(2,3)24-6-12-28(13-7-24)39(37,38)35-17-14-25-18-29-23(19-31(25,22-35)21-34-15-4-5-16-34)20-33-36(29)27-10-8-26(32)9-11-27/h6-13,18,20H,4-5,14-17,19,21-22H2,1-3H3/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372943 (CHEMBL272789) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(C)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C27H30FN3O2S/c1-26(2,3)20-5-11-24(12-6-20)34(32,33)30-14-13-21-15-25-19(16-27(21,4)18-30)17-29-31(25)23-9-7-22(28)8-10-23/h5-12,15,17H,13-14,16,18H2,1-4H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372922 (CHEMBL255950) Show SMILES CN(C)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:10| Show InChI InChI=1S/C29H35FN4O2S/c1-28(2,3)22-6-12-26(13-7-22)37(35,36)33-15-14-23-16-27-21(17-29(23,20-33)19-32(4)5)18-31-34(27)25-10-8-24(30)9-11-25/h6-13,16,18H,14-15,17,19-20H2,1-5H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372966 (CHEMBL270668) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1 |c:12| Show InChI InChI=1S/C27H30FN3O4S/c1-20-3-9-25(10-4-20)36(32,33)30-12-11-22-15-26-21(16-27(22,18-30)19-35-14-13-34-2)17-29-31(26)24-7-5-23(28)6-8-24/h3-10,15,17H,11-14,16,18-19H2,1-2H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372959 (CHEMBL402351) Show SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)c2ccc(cc2)N2CCOCC2)cc1 |w:6.5,c:12| Show InChI InChI=1S/C33H32F2N4O3S/c34-27-3-1-24(2-4-27)20-33-21-25-22-36-39(30-7-5-28(35)6-8-30)32(25)19-26(33)13-14-38(23-33)43(40,41)31-11-9-29(10-12-31)37-15-17-42-18-16-37/h1-12,19,22H,13-18,20-21,23H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372963 (CHEMBL270588) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(CC2(Cc2ccc(F)cc2)C1)cnn3-c1ccc(F)cc1 |w:21.23,t:17| Show InChI InChI=1S/C33H33F2N3O2S/c1-32(2,3)25-6-14-30(15-7-25)41(39,40)37-17-16-26-18-31-24(21-36-38(31)29-12-10-28(35)11-13-29)20-33(26,22-37)19-23-4-8-27(34)9-5-23/h4-15,18,21H,16-17,19-20,22H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372960 (CHEMBL272788) Show SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)c2ccc(F)cc2)cc1 |w:6.5,c:12| Show InChI InChI=1S/C29H24F3N3O2S/c30-23-3-1-20(2-4-23)16-29-17-21-18-33-35(26-9-5-24(31)6-10-26)28(21)15-22(29)13-14-34(19-29)38(36,37)27-11-7-25(32)8-12-27/h1-12,15,18H,13-14,16-17,19H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372927 (CHEMBL256161) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(Cc2ccccc2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C33H34FN3O2S/c1-32(2,3)26-9-15-30(16-10-26)40(38,39)36-18-17-27-19-31-25(22-35-37(31)29-13-11-28(34)12-14-29)21-33(27,23-36)20-24-7-5-4-6-8-24/h4-16,19,22H,17-18,20-21,23H2,1-3H3/t33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372971 (CHEMBL255370) Show SMILES COC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C24H23F2N3O3S/c1-32-16-24-13-17-14-27-29(21-6-2-19(25)3-7-21)23(17)12-18(24)10-11-28(15-24)33(30,31)22-8-4-20(26)5-9-22/h2-9,12,14H,10-11,13,15-16H2,1H3/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372933 (CHEMBL403179) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CN2CCC2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C30H35FN4O2S/c1-29(2,3)23-5-11-27(12-6-23)38(36,37)34-16-13-24-17-28-22(18-30(24,21-34)20-33-14-4-15-33)19-32-35(28)26-9-7-25(31)8-10-26/h5-12,17,19H,4,13-16,18,20-21H2,1-3H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372932 (CHEMBL256894) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@]3(CN4CCCC4)CN(CCC3=Cc12)S(=O)(=O)c1ccccc1 |c:26| Show InChI InChI=1S/C27H29FN4O2S/c28-23-8-10-24(11-9-23)32-26-16-22-12-15-31(35(33,34)25-6-2-1-3-7-25)20-27(22,17-21(26)18-29-32)19-30-13-4-5-14-30/h1-3,6-11,16,18H,4-5,12-15,17,19-20H2/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372961 (CHEMBL403921) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(CC2(Cc2ccc(F)cc2)C1)cnn3-c1ccc(F)cc1 |w:18.20,t:14| Show InChI InChI=1S/C30H27F2N3O2S/c1-21-2-12-28(13-3-21)38(36,37)34-15-14-24-16-29-23(19-33-35(29)27-10-8-26(32)9-11-27)18-30(24,20-34)17-22-4-6-25(31)7-5-22/h2-13,16,19H,14-15,17-18,20H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372978 (CHEMBL270839) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CO)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C27H30FN3O3S/c1-26(2,3)20-4-10-24(11-5-20)35(33,34)30-13-12-21-14-25-19(15-27(21,17-30)18-32)16-29-31(25)23-8-6-22(28)7-9-23/h4-11,14,16,32H,12-13,15,17-18H2,1-3H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372930 (CHEMBL257462) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CN2CCCCC2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C32H39FN4O2S/c1-31(2,3)25-7-13-29(14-8-25)40(38,39)36-18-15-26-19-30-24(21-34-37(30)28-11-9-27(33)10-12-28)20-32(26,23-36)22-35-16-5-4-6-17-35/h7-14,19,21H,4-6,15-18,20,22-23H2,1-3H3/t32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372920 (CHEMBL410037) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@]3(CN4CCCC4)CN(CCC3=Cc12)S(=O)(=O)c1ccc(F)cc1 |c:26| Show InChI InChI=1S/C27H28F2N4O2S/c28-22-3-7-24(8-4-22)33-26-15-21-11-14-32(36(34,35)25-9-5-23(29)6-10-25)19-27(21,16-20(26)17-30-33)18-31-12-1-2-13-31/h3-10,15,17H,1-2,11-14,16,18-19H2/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372945 (CHEMBL404183) Show SMILES COCCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:13| Show InChI InChI=1S/C31H38FN3O4S/c1-30(2,3)24-6-12-28(13-7-24)40(36,37)34-15-14-25-18-29-23(19-31(25,21-34)22-39-17-5-16-38-4)20-33-35(29)27-10-8-26(32)9-11-27/h6-13,18,20H,5,14-17,19,21-22H2,1-4H3/t31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372917 (CHEMBL403761) Show SMILES CCN(CC)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:12| Show InChI InChI=1S/C31H39FN4O2S/c1-6-34(7-2)21-31-19-23-20-33-36(27-12-10-26(32)11-13-27)29(23)18-25(31)16-17-35(22-31)39(37,38)28-14-8-24(9-15-28)30(3,4)5/h8-15,18,20H,6-7,16-17,19,21-22H2,1-5H3/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372976 (CHEMBL271221) Show SMILES CCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:10| Show InChI InChI=1S/C29H34FN3O3S/c1-5-36-20-29-17-21-18-31-33(25-10-8-24(30)9-11-25)27(21)16-23(29)14-15-32(19-29)37(34,35)26-12-6-22(7-13-26)28(2,3)4/h6-13,16,18H,5,14-15,17,19-20H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372923 (CHEMBL257204) Show SMILES CC(C)NC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:11| Show InChI InChI=1S/C30H37FN4O2S/c1-21(2)32-19-30-17-22-18-33-35(26-10-8-25(31)9-11-26)28(22)16-24(30)14-15-34(20-30)38(36,37)27-12-6-23(7-13-27)29(3,4)5/h6-13,16,18,21,32H,14-15,17,19-20H2,1-5H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372962 (CHEMBL271019) Show SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)c2ccccc2)cc1 |w:6.5,c:12| Show InChI InChI=1S/C29H25F2N3O2S/c30-24-8-6-21(7-9-24)17-29-18-22-19-32-34(26-12-10-25(31)11-13-26)28(22)16-23(29)14-15-33(20-29)37(35,36)27-4-2-1-3-5-27/h1-13,16,19H,14-15,17-18,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372946 (CHEMBL273141) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(C)C1)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C24H24FN3O2S/c1-17-3-9-22(10-4-17)31(29,30)27-12-11-19-13-23-18(14-24(19,2)16-27)15-26-28(23)21-7-5-20(25)6-8-21/h3-10,13,15H,11-12,14,16H2,1-2H3/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372924 (CHEMBL404160) Show SMILES CCNC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:10| Show InChI InChI=1S/C29H35FN4O2S/c1-5-31-19-29-17-21-18-32-34(25-10-8-24(30)9-11-25)27(21)16-23(29)14-15-33(20-29)37(35,36)26-12-6-22(7-13-26)28(2,3)4/h6-13,16,18,31H,5,14-15,17,19-20H2,1-4H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372952 (CHEMBL271263) Show SMILES Fc1ccc(CC23CN(Cc4ccccc4)CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)cc1 |w:6.5,c:20| Show InChI InChI=1S/C30H27F2N3/c31-26-8-6-22(7-9-26)17-30-18-24-19-33-35(28-12-10-27(32)11-13-28)29(24)16-25(30)14-15-34(21-30)20-23-4-2-1-3-5-23/h1-13,16,19H,14-15,17-18,20-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372935 (CHEMBL255843) Show SMILES CN(C)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1 |c:10| Show InChI InChI=1S/C25H26F2N4O2S/c1-29(2)16-25-14-18-15-28-31(22-7-3-20(26)4-8-22)24(18)13-19(25)11-12-30(17-25)34(32,33)23-9-5-21(27)6-10-23/h3-10,13,15H,11-12,14,16-17H2,1-2H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372934 (CHEMBL272923) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CNCCO)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C29H35FN4O3S/c1-28(2,3)22-4-10-26(11-5-22)38(36,37)33-14-12-23-16-27-21(17-29(23,20-33)19-31-13-15-35)18-32-34(27)25-8-6-24(30)7-9-25/h4-11,16,18,31,35H,12-15,17,19-20H2,1-3H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372975 (CHEMBL270667) Show SMILES COCCOC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1 |c:12| Show InChI InChI=1S/C26H28FN3O4S/c1-33-13-14-34-19-26-16-20-17-28-30(23-9-7-22(27)8-10-23)25(20)15-21(26)11-12-29(18-26)35(31,32)24-5-3-2-4-6-24/h2-10,15,17H,11-14,16,18-19H2,1H3/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372954 (CHEMBL403178) Show SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)Nc2ccccc2)cc1 |w:6.5,c:12| Show InChI InChI=1S/C29H26F2N4O2S/c30-24-8-6-21(7-9-24)17-29-18-22-19-32-35(27-12-10-25(31)11-13-27)28(22)16-23(29)14-15-34(20-29)38(36,37)33-26-4-2-1-3-5-26/h1-13,16,19,33H,14-15,17-18,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair

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