BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 50039851
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385150 (CHEMBL2035650) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of HPGDS				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385142 (CHEMBL2035651) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385144 (CHEMBL2035653) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8.26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385143 (CHEMBL2035652) Show SMILES O=C(NCCN1CCOCC1)c1ccc(cc1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385149 (CHEMBL2035649) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of HPGDS				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385145 (CHEMBL2035654) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	662	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385147 (CHEMBL2035656) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	845	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385146 (CHEMBL2035655) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM50385148 (CHEMBL2035648) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1ccc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of HPGDS				Bioorg Med Chem Lett 22: 3795-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.004 BindingDB Entry DOI: 10.7270/Q28C9X82
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair