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Compile Data Set for Download or QSAR

Found 59 hits Enz. Inhib. hit(s) with all data for entry = 50040542   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395858
PNG
(CHEMBL2165519)
Show SMILES CN(C)C1CCc2ccc3n(ccc3c2C1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H22N2O2S/c1-21(2)16-10-8-15-9-11-20-18(19(15)14-16)12-13-22(20)25(23,24)17-6-4-3-5-7-17/h3-7,9,11-13,16H,8,10,14H2,1-2H3
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1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HeLa cells after 120 mins by scintillation counter in presence of methiothepin


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50163069
PNG
(1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...)
Show SMILES CN1CCC[C@@H]1Cc1cn(c2ccc(Cl)cc12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H21ClN2O2S/c1-22-11-5-6-17(22)12-15-14-23(20-10-9-16(21)13-19(15)20)26(24,25)18-7-3-2-4-8-18/h2-4,7-10,13-14,17H,5-6,11-12H2,1H3/t17-/m1/s1
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1.40n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human 5-HT6 receptor


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395860
PNG
(CHEMBL2165520)
Show SMILES NC1Cc2cn(c3cccc(C1)c23)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H16N2O2S/c18-14-9-12-5-4-8-16-17(12)13(10-14)11-19(16)22(20,21)15-6-2-1-3-7-15/h1-8,11,14H,9-10,18H2
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1.60n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human 5-HT6 receptor


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395855
PNG
(CHEMBL2165524)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Br)ccc1n2S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H21BrN2O2S/c1-22(2)15-9-11-20-18(13-15)17-12-14(21)8-10-19(17)23(20)26(24,25)16-6-4-3-5-7-16/h3-8,10,12,15H,9,11,13H2,1-2H3
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1.83n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395838
PNG
(CHEMBL2165541)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H21F3N2O2S/c1-25(2)15-10-11-20-18(13-15)17-8-3-4-9-19(17)26(20)29(27,28)16-7-5-6-14(12-16)21(22,23)24/h3-9,12,15H,10-11,13H2,1-2H3
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1.92n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM34141
PNG
(CHEMBL76237 | MS-245)
Show SMILES COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H22N2O3S/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17/h4-10,13-14H,11-12H2,1-3H3
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2.30n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human 5-HT6 receptor


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50130274
PNG
((9-Benzenesulfonyl-6-methoxy-2,3,4,9-tetrahydro-1H...)
Show SMILES COc1ccc2n(c3CCCC(CN(C)C)c3c2c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C22H26N2O3S/c1-23(2)15-16-8-7-11-21-22(16)19-14-17(27-3)12-13-20(19)24(21)28(25,26)18-9-5-4-6-10-18/h4-6,9-10,12-14,16H,7-8,11,15H2,1-3H3
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2.30n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human 5-HT6 receptor


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395839
PNG
(CHEMBL2165540)
Show SMILES CSc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C21H23ClN2O2S2/c1-23(2)15-7-9-20-18(12-15)19-13-16(27-3)8-10-21(19)24(20)28(25,26)17-6-4-5-14(22)11-17/h4-6,8,10-11,13,15H,7,9,12H2,1-3H3
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2.68n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395886
PNG
(CHEMBL2165545)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccccc1Br
Show InChI InChI=1S/C20H21BrN2O2S/c1-22(2)14-11-12-19-16(13-14)15-7-3-5-9-18(15)23(19)26(24,25)20-10-6-4-8-17(20)21/h3-10,14H,11-13H2,1-2H3
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2.85n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395879
PNG
(CHEMBL2165552)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C21H23FN2O3S/c1-23(2)14-8-10-19-16(12-14)17-13-15(27-3)9-11-20(17)24(19)28(25,26)21-7-5-4-6-18(21)22/h4-7,9,11,13-14H,8,10,12H2,1-3H3
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3.63n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395835
PNG
(CHEMBL2165544)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C22H23F3N2O3S/c1-26(2)15-7-9-20-18(12-15)19-13-16(30-3)8-10-21(19)27(20)31(28,29)17-6-4-5-14(11-17)22(23,24)25/h4-6,8,10-11,13,15H,7,9,12H2,1-3H3
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3.71n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395841
PNG
(CHEMBL2165538)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C20H21ClN2O2S/c1-22(2)15-10-11-20-18(13-15)17-8-3-4-9-19(17)23(20)26(24,25)16-7-5-6-14(21)12-16/h3-9,12,15H,10-11,13H2,1-2H3
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4.21n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395883
PNG
(CHEMBL2165548)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccccc1Br
Show InChI InChI=1S/C21H23BrN2O3S/c1-23(2)14-8-10-19-16(12-14)17-13-15(27-3)9-11-20(17)24(19)28(25,26)21-7-5-4-6-18(21)22/h4-7,9,11,13-14H,8,10,12H2,1-3H3
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4.30n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395851
PNG
(CHEMBL2165528)
Show SMILES CSc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H24N2O2S2/c1-22(2)15-9-11-20-18(13-15)19-14-16(26-3)10-12-21(19)23(20)27(24,25)17-7-5-4-6-8-17/h4-8,10,12,14-15H,9,11,13H2,1-3H3
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4.57n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395881
PNG
(CHEMBL2165550)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccccc1Cl
Show InChI InChI=1S/C21H23ClN2O3S/c1-23(2)14-8-10-19-16(12-14)17-13-15(27-3)9-11-20(17)24(19)28(25,26)21-7-5-4-6-18(21)22/h4-7,9,11,13-14H,8,10,12H2,1-3H3
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4.68n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395840
PNG
(CHEMBL2165539)
Show SMILES CN(C)C1CCc2c(C1)c1cc(F)ccc1n2S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C20H20ClFN2O2S/c1-23(2)15-7-9-20-18(12-15)17-11-14(22)6-8-19(17)24(20)27(25,26)16-5-3-4-13(21)10-16/h3-6,8,10-11,15H,7,9,12H2,1-2H3
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5.01n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395884
PNG
(CHEMBL2165547)
Show SMILES CN(C)C1CCc2c(C1)c1cc(F)ccc1n2S(=O)(=O)c1ccccc1Br
Show InChI InChI=1S/C20H20BrFN2O2S/c1-23(2)14-8-10-19-16(12-14)15-11-13(22)7-9-18(15)24(19)27(25,26)20-6-4-3-5-17(20)21/h3-7,9,11,14H,8,10,12H2,1-2H3
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5.02n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395852
PNG
(CHEMBL2165527)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H24N2O3S/c1-22(2)15-9-11-20-18(13-15)19-14-16(26-3)10-12-21(19)23(20)27(24,25)17-7-5-4-6-8-17/h4-8,10,12,14-15H,9,11,13H2,1-3H3
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5.44n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395837
PNG
(CHEMBL2165542)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Br)ccc1n2S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H20BrF3N2O2S/c1-26(2)15-7-9-20-18(12-15)17-11-14(22)6-8-19(17)27(20)30(28,29)16-5-3-4-13(10-16)21(23,24)25/h3-6,8,10-11,15H,7,9,12H2,1-2H3
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5.5n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395874
PNG
(CHEMBL2165557)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C22H26N2O3S/c1-15-5-9-18(10-6-15)28(25,26)24-21-11-7-16(23(2)3)13-19(21)20-14-17(27-4)8-12-22(20)24/h5-6,8-10,12,14,16H,7,11,13H2,1-4H3
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5.89n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395868
PNG
(CHEMBL2165562)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1c2CCC(Cc2c2cc(SC)ccc12)N(C)C
Show InChI InChI=1S/C22H26N2O3S2/c1-23(2)15-5-11-21-19(13-15)20-14-17(28-4)8-12-22(20)24(21)29(25,26)18-9-6-16(27-3)7-10-18/h6-10,12,14-15H,5,11,13H2,1-4H3
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6.89n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50106248
PNG
((4S,5S)-4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3...)
Show SMILES CN(C)[C@H]1Cc2cn(c3cccc([C@@H]1O)c23)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C20H22N2O3S/c1-13-7-9-15(10-8-13)26(24,25)22-12-14-11-18(21(2)3)20(23)16-5-4-6-17(22)19(14)16/h4-10,12,18,20,23H,11H2,1-3H3/t18-,20-/m0/s1
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7.20n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human 5-HT6 receptor


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395873
PNG
(CHEMBL2165558)
Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)n1c2CCC(Cc2c2cc(Br)ccc12)N(C)C
Show InChI InChI=1S/C23H27BrN2O2S/c1-15(2)16-5-9-19(10-6-16)29(27,28)26-22-11-7-17(24)13-20(22)21-14-18(25(3)4)8-12-23(21)26/h5-7,9-11,13,15,18H,8,12,14H2,1-4H3
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7.5n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395850
PNG
(CHEMBL2165529)
Show SMILES CN(C)C1CCc2c(C1)c1cc(F)cc(F)c1n2S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H20F2N2O2S/c1-23(2)14-8-9-19-16(12-14)17-10-13(21)11-18(22)20(17)24(19)27(25,26)15-6-4-3-5-7-15/h3-7,10-11,14H,8-9,12H2,1-2H3
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7.95n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395885
PNG
(CHEMBL2165546)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Cl)ccc1n2S(=O)(=O)c1ccccc1Br
Show InChI InChI=1S/C20H20BrClN2O2S/c1-23(2)14-8-10-19-16(12-14)15-11-13(22)7-9-18(15)24(19)27(25,26)20-6-4-3-5-17(20)21/h3-7,9,11,14H,8,10,12H2,1-2H3
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8.13n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395878
PNG
(CHEMBL2165553)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C21H24N2O2S/c1-15-8-11-17(12-9-15)26(24,25)23-20-7-5-4-6-18(20)19-14-16(22(2)3)10-13-21(19)23/h4-9,11-12,16H,10,13-14H2,1-3H3
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8.28n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395856
PNG
(CHEMBL2165523)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H22N2O2S/c1-21(2)15-12-13-20-18(14-15)17-10-6-7-11-19(17)22(20)25(23,24)16-8-4-3-5-9-16/h3-11,15H,12-14H2,1-2H3
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8.82n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395882
PNG
(CHEMBL2165549)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccccc1Cl
Show InChI InChI=1S/C20H21ClN2O2S/c1-22(2)14-11-12-19-16(13-14)15-7-3-5-9-18(15)23(19)26(24,25)20-10-6-4-8-17(20)21/h3-10,14H,11-13H2,1-2H3
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9.15n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395880
PNG
(CHEMBL2165551)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C20H21FN2O2S/c1-22(2)14-11-12-19-16(13-14)15-7-3-5-9-18(15)23(19)26(24,25)20-10-6-4-8-17(20)21/h3-10,14H,11-13H2,1-2H3
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10.4n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395836
PNG
(CHEMBL2165543)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Cl)ccc1n2S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H20ClF3N2O2S/c1-26(2)15-7-9-20-18(12-15)17-11-14(22)6-8-19(17)27(20)30(28,29)16-5-3-4-13(10-16)21(23,24)25/h3-6,8,10-11,15H,7,9,12H2,1-2H3
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12.2n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395845
PNG
(CHEMBL2165534)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C20H21FN2O2S/c1-22(2)15-9-12-20-18(13-15)17-5-3-4-6-19(17)23(20)26(24,25)16-10-7-14(21)8-11-16/h3-8,10-11,15H,9,12-13H2,1-2H3
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12.5n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395863
PNG
(CHEMBL2165567)
Show SMILES CNC1CCc2c(C1)c1cc(OC)ccc1n2S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H21F3N2O3S/c1-25-14-6-8-19-17(11-14)18-12-15(29-2)7-9-20(18)26(19)30(27,28)16-5-3-4-13(10-16)21(22,23)24/h3-5,7,9-10,12,14,25H,6,8,11H2,1-2H3
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13.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395875
PNG
(CHEMBL2165556)
Show SMILES CSc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C22H26N2O2S2/c1-15-5-9-18(10-6-15)28(25,26)24-21-11-7-16(23(2)3)13-19(21)20-14-17(27-4)8-12-22(20)24/h5-6,8-10,12,14,16H,7,11,13H2,1-4H3
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13.8n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395846
PNG
(CHEMBL2165533)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C21H23BrN2O3S/c1-23(2)15-6-10-20-18(12-15)19-13-16(27-3)7-11-21(19)24(20)28(25,26)17-8-4-14(22)5-9-17/h4-5,7-9,11,13,15H,6,10,12H2,1-3H3
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15.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395872
PNG
(CHEMBL2165559)
Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)n1c2CCC(Cc2c2cc(F)ccc12)N(C)C
Show InChI InChI=1S/C23H27FN2O2S/c1-15(2)16-5-9-19(10-6-16)29(27,28)26-22-11-7-17(24)13-20(22)21-14-18(25(3)4)8-12-23(21)26/h5-7,9-11,13,15,18H,8,12,14H2,1-4H3
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15.5n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395849
PNG
(CHEMBL2165530)
Show SMILES CN(C)C1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C20H21BrN2O2S/c1-22(2)15-9-12-20-18(13-15)17-5-3-4-6-19(17)23(20)26(24,25)16-10-7-14(21)8-11-16/h3-8,10-11,15H,9,12-13H2,1-2H3
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15.5n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395853
PNG
(CHEMBL2165526)
Show SMILES CN(C)C1CCc2c(C1)c1cc(F)ccc1n2S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H21FN2O2S/c1-22(2)15-9-11-20-18(13-15)17-12-14(21)8-10-19(17)23(20)26(24,25)16-6-4-3-5-7-16/h3-8,10,12,15H,9,11,13H2,1-2H3
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15.7n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395854
PNG
(CHEMBL2165525)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Cl)ccc1n2S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H21ClN2O2S/c1-22(2)15-9-11-20-18(13-15)17-12-14(21)8-10-19(17)23(20)26(24,25)16-6-4-3-5-7-16/h3-8,10,12,15H,9,11,13H2,1-2H3
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16.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395864
PNG
(CHEMBL2165566)
Show SMILES CNC1CCc2c(C1)c1ccccc1n2S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H19F3N2O2S/c1-24-14-9-10-19-17(12-14)16-7-2-3-8-18(16)25(19)28(26,27)15-6-4-5-13(11-15)20(21,22)23/h2-8,11,14,24H,9-10,12H2,1H3
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17.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395877
PNG
(CHEMBL2165554)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Cl)ccc1n2S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C21H23ClN2O2S/c1-14-4-8-17(9-5-14)27(25,26)24-20-10-6-15(22)12-18(20)19-13-16(23(2)3)7-11-21(19)24/h4-6,8-10,12,16H,7,11,13H2,1-3H3
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18.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395869
PNG
(CHEMBL2163369)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1c2CCC(Cc2c2cc(OC)ccc12)N(C)C
Show InChI InChI=1S/C22H26N2O4S/c1-23(2)15-5-11-21-19(13-15)20-14-17(28-4)8-12-22(20)24(21)29(25,26)18-9-6-16(27-3)7-10-18/h6-10,12,14-15H,5,11,13H2,1-4H3
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19.8n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395871
PNG
(CHEMBL2165560)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1c2CCC(Cc2c2ccccc12)N(C)C
Show InChI InChI=1S/C21H24N2O3S/c1-22(2)15-8-13-21-19(14-15)18-6-4-5-7-20(18)23(21)27(24,25)17-11-9-16(26-3)10-12-17/h4-7,9-12,15H,8,13-14H2,1-3H3
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20.4n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395843
PNG
(CHEMBL2165536)
Show SMILES COc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C21H23FN2O3S/c1-23(2)15-6-10-20-18(12-15)19-13-16(27-3)7-11-21(19)24(20)28(25,26)17-8-4-14(22)5-9-17/h4-5,7-9,11,13,15H,6,10,12H2,1-3H3
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24.3n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395842
PNG
(CHEMBL2165537)
Show SMILES CSc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C21H23FN2O2S2/c1-23(2)15-6-10-20-18(12-15)19-13-16(27-3)7-11-21(19)24(20)28(25,26)17-8-4-14(22)5-9-17/h4-5,7-9,11,13,15H,6,10,12H2,1-3H3
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24.9n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395870
PNG
(CHEMBL2165561)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1c2CCC(Cc2c2cc(Br)ccc12)N(C)C
Show InChI InChI=1S/C21H23BrN2O3S/c1-23(2)15-5-11-21-19(13-15)18-12-14(22)4-10-20(18)24(21)28(25,26)17-8-6-16(27-3)7-9-17/h4,6-10,12,15H,5,11,13H2,1-3H3
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29.0n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395865
PNG
(CHEMBL2165565)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Br)ccc1n2S(=O)(=O)c1ccc(F)c(F)c1
Show InChI InChI=1S/C20H19BrF2N2O2S/c1-24(2)13-4-8-20-16(10-13)15-9-12(21)3-7-19(15)25(20)28(26,27)14-5-6-17(22)18(23)11-14/h3,5-7,9,11,13H,4,8,10H2,1-2H3
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29.0n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395876
PNG
(CHEMBL2165555)
Show SMILES CN(C)C1CCc2c(C1)c1cc(F)ccc1n2S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C21H23FN2O2S/c1-14-4-8-17(9-5-14)27(25,26)24-20-10-6-15(22)12-18(20)19-13-16(23(2)3)7-11-21(19)24/h4-6,8-10,12,16H,7,11,13H2,1-3H3
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32.4n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395844
PNG
(CHEMBL2165535)
Show SMILES CN(C)C1CCc2c(C1)c1cc(F)ccc1n2S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C20H20F2N2O2S/c1-23(2)15-6-10-20-18(12-15)17-11-14(22)5-9-19(17)24(20)27(25,26)16-7-3-13(21)4-8-16/h3-5,7-9,11,15H,6,10,12H2,1-2H3
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32.8n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395861
PNG
(CHEMBL2163740)
Show SMILES COc1ccc2n(c3CCC(N)Cc3c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H19F3N2O3S/c1-28-14-6-8-19-17(11-14)16-10-13(24)5-7-18(16)25(19)29(26,27)15-4-2-3-12(9-15)20(21,22)23/h2-4,6,8-9,11,13H,5,7,10,24H2,1H3
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39.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50395848
PNG
(CHEMBL2165531)
Show SMILES CN(C)C1CCc2c(C1)c1cc(Cl)ccc1n2S(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C20H20BrClN2O2S/c1-23(2)15-6-10-20-18(12-15)17-11-14(22)5-9-19(17)24(20)27(25,26)16-7-3-13(21)4-8-16/h3-5,7-9,11,15H,6,10,12H2,1-2H3
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41.1n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 22: 6980-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.002
BindingDB Entry DOI: 10.7270/Q2QZ2C3F
More data for this
Ligand-Target Pair
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