Compile Data Set for Download or QSAR

Found 56 hits Enz. Inhib. hit(s) with all data for entry = 50040935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402386 (CHEMBL2207747) Show SMILES CC(=O)NC1CC2CCC(C1)N2CCc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8,THB:12:11:4.5.10:7.8| Show InChI InChI=1S/C23H26N4O2S/c1-15(28)25-17-13-18-6-7-19(14-17)27(18)12-10-16-4-8-20(9-5-16)29-23-26-22-21(30-23)3-2-11-24-22/h2-5,8-9,11,17-19H,6-7,10,12-14H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402382 (CHEMBL2207751) Show SMILES CC(=O)NC1CC2CCC(C1)N2Cc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8| Show InChI InChI=1S/C22H24N4O2S/c1-14(27)24-16-11-17-6-7-18(12-16)26(17)13-15-4-8-19(9-5-15)28-22-25-21-20(29-22)3-2-10-23-21/h2-5,8-10,16-18H,6-7,11-13H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402391 (CHEMBL2207742) Show SMILES C(Cc1ccc(Oc2nc3ncccc3s2)cc1)N1CCCCC1 Show InChI InChI=1S/C19H21N3OS/c1-2-12-22(13-3-1)14-10-15-6-8-16(9-7-15)23-19-21-18-17(24-19)5-4-11-20-18/h4-9,11H,1-3,10,12-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402403 (CHEMBL2207730) Show SMILES C(N1CCCCC1)c1ccc(Oc2nc3ncccc3s2)cc1 Show InChI InChI=1S/C18H19N3OS/c1-2-11-21(12-3-1)13-14-6-8-15(9-7-14)22-18-20-17-16(23-18)5-4-10-19-17/h4-10H,1-3,11-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402384 (CHEMBL2207749) Show SMILES CC(=O)N1CC2CN(Cc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 Show InChI InChI=1S/C21H22N4O2S/c1-14(26)25-12-16-10-24(11-17(16)13-25)9-15-4-6-18(7-5-15)27-21-23-20-19(28-21)3-2-8-22-20/h2-8,16-17H,9-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402392 (CHEMBL2207741) Show SMILES CC(=O)NC1CC2CCC(C1)N2CCOc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8| Show InChI InChI=1S/C23H26N4O3S/c1-15(28)25-16-13-17-4-5-18(14-16)27(17)11-12-29-19-6-8-20(9-7-19)30-23-26-22-21(31-23)3-2-10-24-22/h2-3,6-10,16-18H,4-5,11-14H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402383 (CHEMBL2207750) Show SMILES CC(=O)N1CC2CC1CN2Cc1ccc(Oc2nc3ncccc3s2)cc1 |THB:10:9:6:4.3,1:3:8.9:6| Show InChI InChI=1S/C20H20N4O2S/c1-13(25)24-12-15-9-16(24)11-23(15)10-14-4-6-17(7-5-14)26-20-22-19-18(27-20)3-2-8-21-19/h2-8,15-16H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402405 (CHEMBL2207752) Show SMILES NC(=O)C1CCN(Cc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C19H20N4O2S/c20-17(24)14-7-10-23(11-8-14)12-13-3-5-15(6-4-13)25-19-22-18-16(26-19)2-1-9-21-18/h1-6,9,14H,7-8,10-12H2,(H2,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402385 (CHEMBL2207748) Show SMILES O=C1CCCN1C1CCN(Cc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C22H24N4O2S/c27-20-4-2-12-26(20)17-9-13-25(14-10-17)15-16-5-7-18(8-6-16)28-22-24-21-19(29-22)3-1-11-23-21/h1,3,5-8,11,17H,2,4,9-10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402388 (CHEMBL2207745) Show SMILES CC(=O)N1CC2CN(CCc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 Show InChI InChI=1S/C22H24N4O2S/c1-15(27)26-13-17-11-25(12-18(17)14-26)10-8-16-4-6-19(7-5-16)28-22-24-21-20(29-22)3-2-9-23-21/h2-7,9,17-18H,8,10-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402395 (CHEMBL2207738) Show SMILES O=C1CCCN1C1CCN(CCOc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C23H26N4O3S/c28-21-4-2-12-27(21)17-9-13-26(14-10-17)15-16-29-18-5-7-19(8-6-18)30-23-25-22-20(31-23)3-1-11-24-22/h1,3,5-8,11,17H,2,4,9-10,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402393 (CHEMBL2207740) Show SMILES CC(=O)N1CC2CC1CN2CCOc1ccc(Oc2nc3ncccc3s2)cc1 |THB:10:9:6:4.3,1:3:8.9:6| Show InChI InChI=1S/C21H22N4O3S/c1-14(26)25-13-15-11-16(25)12-24(15)9-10-27-17-4-6-18(7-5-17)28-21-23-20-19(29-21)3-2-8-22-20/h2-8,15-16H,9-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402394 (CHEMBL2207739) Show SMILES CC(=O)N1CC2CN(CCOc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 Show InChI InChI=1S/C22H24N4O3S/c1-15(27)26-13-16-11-25(12-17(16)14-26)9-10-28-18-4-6-19(7-5-18)29-22-24-21-20(30-22)3-2-8-23-21/h2-8,16-17H,9-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402397 (CHEMBL2207736) Show SMILES C(CN1CCCCC1)Oc1ccc(Oc2nc3ncccc3s2)cc1 Show InChI InChI=1S/C19H21N3O2S/c1-2-11-22(12-3-1)13-14-23-15-6-8-16(9-7-15)24-19-21-18-17(25-19)5-4-10-20-18/h4-10H,1-3,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402390 (CHEMBL2207743) Show SMILES NC(=O)C1CCN(CCc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C20H22N4O2S/c21-18(25)15-8-12-24(13-9-15)11-7-14-3-5-16(6-4-14)26-20-23-19-17(27-20)2-1-10-22-19/h1-6,10,15H,7-9,11-13H2,(H2,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402387 (CHEMBL2207746) Show SMILES CC(=O)N1CC2CC1CN2CCc1ccc(Oc2nc3ncccc3s2)cc1 |THB:1:3:8.9:6,10:9:6:4.3| Show InChI InChI=1S/C21H22N4O2S/c1-14(26)25-13-16-11-17(25)12-24(16)10-8-15-4-6-18(7-5-15)27-21-23-20-19(28-21)3-2-9-22-20/h2-7,9,16-17H,8,10-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402389 (CHEMBL2207744) Show SMILES O=C1CCCN1C1CCN(CCc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C23H26N4O2S/c28-21-4-2-13-27(21)18-10-15-26(16-11-18)14-9-17-5-7-19(8-6-17)29-23-25-22-20(30-23)3-1-12-24-22/h1,3,5-8,12,18H,2,4,9-11,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402396 (CHEMBL2207737) Show SMILES NC(=O)C1CCN(CCOc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C20H22N4O3S/c21-18(25)14-7-10-24(11-8-14)12-13-26-15-3-5-16(6-4-15)27-20-23-19-17(28-20)2-1-9-22-19/h1-6,9,14H,7-8,10-13H2,(H2,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402398 (CHEMBL2207735) Show SMILES Fc1cnc2nc(Oc3ccc(CN4CCCCC4)cc3)sc2c1 Show InChI InChI=1S/C18H18FN3OS/c19-14-10-16-17(20-11-14)21-18(24-16)23-15-6-4-13(5-7-15)12-22-8-2-1-3-9-22/h4-7,10-11H,1-3,8-9,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402400 (CHEMBL2207733) Show SMILES Cc1ccnc2nc(Oc3ccc(CN4CCCCC4)cc3)sc12 Show InChI InChI=1S/C19H21N3OS/c1-14-9-10-20-18-17(14)24-19(21-18)23-16-7-5-15(6-8-16)13-22-11-3-2-4-12-22/h5-10H,2-4,11-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402399 (CHEMBL2207734) Show SMILES Clc1cnc2nc(Oc3ccc(CN4CCCCC4)cc3)sc2c1 Show InChI InChI=1S/C18H18ClN3OS/c19-14-10-16-17(20-11-14)21-18(24-16)23-15-6-4-13(5-7-15)12-22-8-2-1-3-9-22/h4-7,10-11H,1-3,8-9,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402402 (CHEMBL2207731) Show SMILES C(N1CCCCC1)c1ccc(Oc2nc3ccncc3s2)cc1 Show InChI InChI=1S/C18H19N3OS/c1-2-10-21(11-3-1)13-14-4-6-15(7-5-14)22-18-20-16-8-9-19-12-17(16)23-18/h4-9,12H,1-3,10-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	614	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402404 (CHEMBL2207729) Show SMILES NC(=O)C1CCN(Cc2ccc(Oc3nc4cccnc4s3)cc2)CC1 Show InChI InChI=1S/C19H20N4O2S/c20-17(24)14-7-10-23(11-8-14)12-13-3-5-15(6-4-13)25-19-22-16-2-1-9-21-18(16)26-19/h1-6,9,14H,7-8,10-12H2,(H2,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	733	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM24233 (1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}pipe...) Show SMILES NC(=O)C1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C20H21N3O2S/c21-19(24)15-9-11-23(12-10-15)13-14-5-7-16(8-6-14)25-20-22-17-3-1-2-4-18(17)26-20/h1-8,15H,9-13H2,(H2,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50402401 (CHEMBL2207732) Show SMILES C(N1CCCCC1)c1ccc(Oc2nc3cnccc3s2)cc1 Show InChI InChI=1S/C18H19N3OS/c1-2-10-21(11-3-1)13-14-4-6-15(7-5-14)22-18-20-16-12-19-9-8-17(16)23-18/h4-9,12H,1-3,10-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402395 (CHEMBL2207738) Show SMILES O=C1CCCN1C1CCN(CCOc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C23H26N4O3S/c28-21-4-2-12-27(21)17-9-13-26(14-10-17)15-16-29-18-5-7-19(8-6-18)30-23-25-22-20(31-23)3-1-11-24-22/h1,3,5-8,11,17H,2,4,9-10,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402389 (CHEMBL2207744) Show SMILES O=C1CCCN1C1CCN(CCc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C23H26N4O2S/c28-21-4-2-13-27(21)18-10-15-26(16-11-18)14-9-17-5-7-19(8-6-17)29-23-25-22-20(30-23)3-1-12-24-22/h1,3,5-8,12,18H,2,4,9-11,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402386 (CHEMBL2207747) Show SMILES CC(=O)NC1CC2CCC(C1)N2CCc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8,THB:12:11:4.5.10:7.8| Show InChI InChI=1S/C23H26N4O2S/c1-15(28)25-17-13-18-6-7-19(14-17)27(18)12-10-16-4-8-20(9-5-16)29-23-26-22-21(30-23)3-2-11-24-22/h2-5,8-9,11,17-19H,6-7,10,12-14H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402400 (CHEMBL2207733) Show SMILES Cc1ccnc2nc(Oc3ccc(CN4CCCCC4)cc3)sc12 Show InChI InChI=1S/C19H21N3OS/c1-14-9-10-20-18-17(14)24-19(21-18)23-16-7-5-15(6-8-16)13-22-11-3-2-4-12-22/h5-10H,2-4,11-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402386 (CHEMBL2207747) Show SMILES CC(=O)NC1CC2CCC(C1)N2CCc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8,THB:12:11:4.5.10:7.8| Show InChI InChI=1S/C23H26N4O2S/c1-15(28)25-17-13-18-6-7-19(14-17)27(18)12-10-16-4-8-20(9-5-16)29-23-26-22-21(30-23)3-2-11-24-22/h2-5,8-9,11,17-19H,6-7,10,12-14H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402405 (CHEMBL2207752) Show SMILES NC(=O)C1CCN(Cc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C19H20N4O2S/c20-17(24)14-7-10-23(11-8-14)12-13-3-5-15(6-4-13)25-19-22-18-16(26-19)2-1-9-21-18/h1-6,9,14H,7-8,10-12H2,(H2,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM24238 (Benzthiazole compound, 33p | N-(1-{[4-(1,3-benzoth...) Show SMILES OCC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C21H23N3O3S/c25-14-20(26)22-16-9-11-24(12-10-16)13-15-5-7-17(8-6-15)27-21-23-18-3-1-2-4-19(18)28-21/h1-8,16,25H,9-14H2,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402398 (CHEMBL2207735) Show SMILES Fc1cnc2nc(Oc3ccc(CN4CCCCC4)cc3)sc2c1 Show InChI InChI=1S/C18H18FN3OS/c19-14-10-16-17(20-11-14)21-18(24-16)23-15-6-4-13(5-7-15)12-22-8-2-1-3-9-22/h4-7,10-11H,1-3,8-9,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402385 (CHEMBL2207748) Show SMILES O=C1CCCN1C1CCN(Cc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C22H24N4O2S/c27-20-4-2-12-26(20)17-9-13-25(14-10-17)15-16-5-7-18(8-6-16)28-22-24-21-19(29-22)3-1-11-23-21/h1,3,5-8,11,17H,2,4,9-10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402405 (CHEMBL2207752) Show SMILES NC(=O)C1CCN(Cc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C19H20N4O2S/c20-17(24)14-7-10-23(11-8-14)12-13-3-5-15(6-4-13)25-19-22-18-16(26-19)2-1-9-21-18/h1-6,9,14H,7-8,10-12H2,(H2,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402384 (CHEMBL2207749) Show SMILES CC(=O)N1CC2CN(Cc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 Show InChI InChI=1S/C21H22N4O2S/c1-14(26)25-12-16-10-24(11-17(16)13-25)9-15-4-6-18(7-5-15)27-21-23-20-19(28-21)3-2-8-22-20/h2-8,16-17H,9-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402383 (CHEMBL2207750) Show SMILES CC(=O)N1CC2CC1CN2Cc1ccc(Oc2nc3ncccc3s2)cc1 |THB:10:9:6:4.3,1:3:8.9:6| Show InChI InChI=1S/C20H20N4O2S/c1-13(25)24-12-15-9-16(24)11-23(15)10-14-4-6-17(7-5-14)26-20-22-19-18(27-20)3-2-8-21-19/h2-8,15-16H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402382 (CHEMBL2207751) Show SMILES CC(=O)NC1CC2CCC(C1)N2Cc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8| Show InChI InChI=1S/C22H24N4O2S/c1-14(27)24-16-11-17-6-7-18(12-16)26(17)13-15-4-8-19(9-5-15)28-22-25-21-20(29-22)3-2-10-23-21/h2-5,8-10,16-18H,6-7,11-13H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM24239 (1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}pipe...) Show SMILES OC(=O)C1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C20H20N2O3S/c23-19(24)15-9-11-22(12-10-15)13-14-5-7-16(8-6-14)25-20-21-17-3-1-2-4-18(17)26-20/h1-8,15H,9-13H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402403 (CHEMBL2207730) Show SMILES C(N1CCCCC1)c1ccc(Oc2nc3ncccc3s2)cc1 Show InChI InChI=1S/C18H19N3OS/c1-2-11-21(12-3-1)13-14-6-8-15(9-7-14)22-18-20-17-16(23-18)5-4-10-19-17/h4-10H,1-3,11-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402397 (CHEMBL2207736) Show SMILES C(CN1CCCCC1)Oc1ccc(Oc2nc3ncccc3s2)cc1 Show InChI InChI=1S/C19H21N3O2S/c1-2-11-22(12-3-1)13-14-23-15-6-8-16(9-7-15)24-19-21-18-17(25-19)5-4-10-20-18/h4-10H,1-3,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402396 (CHEMBL2207737) Show SMILES NC(=O)C1CCN(CCOc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C20H22N4O3S/c21-18(25)14-7-10-24(11-8-14)12-13-26-15-3-5-16(6-4-15)27-20-23-19-17(28-20)2-1-9-22-19/h1-6,9,14H,7-8,10-13H2,(H2,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402395 (CHEMBL2207738) Show SMILES O=C1CCCN1C1CCN(CCOc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C23H26N4O3S/c28-21-4-2-12-27(21)17-9-13-26(14-10-17)15-16-29-18-5-7-19(8-6-18)30-23-25-22-20(31-23)3-1-11-24-22/h1,3,5-8,11,17H,2,4,9-10,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402394 (CHEMBL2207739) Show SMILES CC(=O)N1CC2CN(CCOc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 Show InChI InChI=1S/C22H24N4O3S/c1-15(27)26-13-16-11-25(12-17(16)14-26)9-10-28-18-4-6-19(7-5-18)29-22-24-21-20(30-22)3-2-8-23-21/h2-8,16-17H,9-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402393 (CHEMBL2207740) Show SMILES CC(=O)N1CC2CC1CN2CCOc1ccc(Oc2nc3ncccc3s2)cc1 |THB:10:9:6:4.3,1:3:8.9:6| Show InChI InChI=1S/C21H22N4O3S/c1-14(26)25-13-15-11-16(25)12-24(15)9-10-27-17-4-6-18(7-5-17)28-21-23-20-19(29-21)3-2-8-22-20/h2-8,15-16H,9-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402392 (CHEMBL2207741) Show SMILES CC(=O)NC1CC2CCC(C1)N2CCOc1ccc(Oc2nc3ncccc3s2)cc1 |TLB:3:4:11:7.8| Show InChI InChI=1S/C23H26N4O3S/c1-15(28)25-16-13-17-4-5-18(14-16)27(17)11-12-29-19-6-8-20(9-7-19)30-23-26-22-21(31-23)3-2-10-24-22/h2-3,6-10,16-18H,4-5,11-14H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402391 (CHEMBL2207742) Show SMILES C(Cc1ccc(Oc2nc3ncccc3s2)cc1)N1CCCCC1 Show InChI InChI=1S/C19H21N3OS/c1-2-12-22(13-3-1)14-10-15-6-8-16(9-7-15)23-19-21-18-17(24-19)5-4-11-20-18/h4-9,11H,1-3,10,12-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402390 (CHEMBL2207743) Show SMILES NC(=O)C1CCN(CCc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C20H22N4O2S/c21-18(25)15-8-12-24(13-9-15)11-7-14-3-5-16(6-4-14)26-20-23-19-17(27-20)2-1-10-22-19/h1-6,10,15H,7-9,11-13H2,(H2,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402389 (CHEMBL2207744) Show SMILES O=C1CCCN1C1CCN(CCc2ccc(Oc3nc4ncccc4s3)cc2)CC1 Show InChI InChI=1S/C23H26N4O2S/c28-21-4-2-13-27(21)18-10-15-26(16-11-18)14-9-17-5-7-19(8-6-17)29-23-25-22-20(30-23)3-1-12-24-22/h1,3,5-8,12,18H,2,4,9-11,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402388 (CHEMBL2207745) Show SMILES CC(=O)N1CC2CN(CCc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 Show InChI InChI=1S/C22H24N4O2S/c1-15(27)26-13-17-11-25(12-18(17)14-26)10-8-16-4-6-19(7-5-16)28-22-24-21-20(29-22)3-2-9-23-21/h2-7,9,17-18H,8,10-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 7504-11 (2012) Article DOI: 10.1016/j.bmcl.2012.10.036 BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
					More data for this Ligand-Target Pair

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