Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407259 (CHEMBL342041) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407260 (CHEMBL135203) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407261 (CHEMBL137575) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.15 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407262 (CHEMBL135672) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50002692 ((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407269 (CHEMBL138540) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.72E+3 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407264 (CHEMBL334917) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.79E+3 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407265 (CHEMBL334551) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.27 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407266 (CHEMBL137294) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 6.75 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407267 (CHEMBL132707) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407268 (CHEMBL136976) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.17 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50407263 (CHEMBL137765) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 865 | n/a | n/a | n/a | n/a |
University of Alberta Curated by ChEMBL | Assay Description Effective concentration in vitro agaianst HIV-1-infected CEM cells relative to uninfected untreated controls | J Med Chem 37: 4297-306 (1995) BindingDB Entry DOI: 10.7270/Q2NP25M9 | |||||||||||
More data for this Ligand-Target Pair |