Compile Data Set for Download or QSAR

Found 100 hits Enz. Inhib. hit(s) with all data for entry = 50042393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425360 (CHEMBL2316207) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(cc4C3=O)C(=O)NCCN3CCOCC3)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C35H33FN4O4/c36-31-13-11-28(22-32(31)39-35(43)24-4-2-1-3-5-24)38-27-10-12-29-25(20-27)8-6-23-7-9-26(21-30(23)33(29)41)34(42)37-14-15-40-16-18-44-19-17-40/h1-5,7,9-13,20-22,38H,6,8,14-19H2,(H,37,42)(H,39,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425359 (CHEMBL2316490) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C32H30FN3O4S/c33-29-8-5-25(18-30(29)35-32(38)23-9-16-41-20-23)34-24-4-7-27-22(17-24)2-1-21-3-6-26(19-28(21)31(27)37)40-15-12-36-10-13-39-14-11-36/h3-9,16-20,34H,1-2,10-15H2,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425384 (CHEMBL2316466) Show SMILES Fc1cc(F)c(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C32H29F2N3O4S/c33-27-17-28(34)30(36-32(39)22-7-14-42-19-22)18-29(27)35-23-4-6-25-21(15-23)2-1-20-3-5-24(16-26(20)31(25)38)41-13-10-37-8-11-40-12-9-37/h3-7,14-19,35H,1-2,8-13H2,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425358 (CHEMBL2316491) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1cccs1 Show InChI InChI=1S/C32H30FN3O4S/c33-28-10-7-24(19-29(28)35-32(38)30-2-1-17-41-30)34-23-6-9-26-22(18-23)4-3-21-5-8-25(20-27(21)31(26)37)40-16-13-36-11-14-39-15-12-36/h1-2,5-10,17-20,34H,3-4,11-16H2,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425352 (CHEMBL2316486) Show SMILES OC[C@H](O)COc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5ccccc5)c4)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C31H27FN2O5/c32-28-13-10-23(15-29(28)34-31(38)20-4-2-1-3-5-20)33-22-9-12-26-21(14-22)7-6-19-8-11-25(16-27(19)30(26)37)39-18-24(36)17-35/h1-5,8-16,24,33,35-36H,6-7,17-18H2,(H,34,38)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425356 (CHEMBL2316489) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccoc1 Show InChI InChI=1S/C32H30FN3O5/c33-29-8-5-25(18-30(29)35-32(38)23-9-13-40-20-23)34-24-4-7-27-22(17-24)2-1-21-3-6-26(19-28(21)31(27)37)41-16-12-36-10-14-39-15-11-36/h3-9,13,17-20,34H,1-2,10-12,14-16H2,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425355 (CHEMBL2316494) Show SMILES Cc1cc(F)c(NC(=O)c2ccoc2)cc1Nc1ccc2c(CCc3ccc(OCCN4CCOCC4)cc3C2=O)c1 Show InChI InChI=1S/C33H32FN3O5/c1-21-16-29(34)31(36-33(39)24-8-12-41-20-24)19-30(21)35-25-5-7-27-23(17-25)3-2-22-4-6-26(18-28(22)32(27)38)42-15-11-37-9-13-40-14-10-37/h4-8,12,16-20,35H,2-3,9-11,13-15H2,1H3,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425354 (CHEMBL2316497) Show SMILES Fc1cc(F)c(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C34H31F2N3O4/c35-29-20-30(36)32(38-34(41)23-4-2-1-3-5-23)21-31(29)37-25-9-11-27-24(18-25)7-6-22-8-10-26(19-28(22)33(27)40)43-17-14-39-12-15-42-16-13-39/h1-5,8-11,18-21,37H,6-7,12-17H2,(H,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425353 (CHEMBL2316206) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(cc4C3=O)C(=O)OCCN3CCOCC3)c2)c(F)c1 Show InChI InChI=1S/C28H26F2N2O4/c29-21-5-8-26(25(30)17-21)31-22-6-7-23-19(15-22)3-1-18-2-4-20(16-24(18)27(23)33)28(34)36-14-11-32-9-12-35-13-10-32/h2,4-8,15-17,31H,1,3,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425352 (CHEMBL2316486) Show SMILES OC[C@H](O)COc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5ccccc5)c4)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C31H27FN2O5/c32-28-13-10-23(15-29(28)34-31(38)20-4-2-1-3-5-20)33-22-9-12-26-21(14-22)7-6-19-8-11-25(16-27(19)30(26)37)39-18-24(36)17-35/h1-5,8-16,24,33,35-36H,6-7,17-18H2,(H,34,38)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425357 (CHEMBL2316485) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C34H32FN3O4/c35-31-13-10-27(21-32(31)37-34(40)24-4-2-1-3-5-24)36-26-9-12-29-25(20-26)7-6-23-8-11-28(22-30(23)33(29)39)42-19-16-38-14-17-41-18-15-38/h1-5,8-13,20-22,36H,6-7,14-19H2,(H,37,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425347 (CHEMBL2316474) Show SMILES CSCCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H22F2N2O2S/c1-32-11-10-28-25(31)17-5-3-15-2-4-16-12-19(7-8-20(16)24(30)21(15)13-17)29-23-9-6-18(26)14-22(23)27/h3,5-9,12-14,29H,2,4,10-11H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425351 (CHEMBL2316483) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5ccccc5)c4)ccc3C(=O)c2c1 Show InChI InChI=1S/C30H25FN2O4/c31-27-13-10-23(17-28(27)33-30(36)20-4-2-1-3-5-20)32-22-9-12-25-21(16-22)7-6-19-8-11-24(37-15-14-34)18-26(19)29(25)35/h1-5,8-13,16-18,32,34H,6-7,14-15H2,(H,33,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425350 (CHEMBL2316488) Show SMILES OCCOc1ccc2CCc3cc(Nc4cc(NC(=O)c5ccccc5)ccc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C30H25FN2O4/c31-27-13-10-23(33-30(36)20-4-2-1-3-5-20)17-28(27)32-22-9-12-25-21(16-22)7-6-19-8-11-24(37-15-14-34)18-26(19)29(25)35/h1-5,8-13,16-18,32,34H,6-7,14-15H2,(H,33,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425349 (CHEMBL2316492) Show SMILES CC1(C)OC[C@H](COc2ccc3CCc4cc(Nc5ccc(F)c(NC(=O)c6cccs6)c5)ccc4C(=O)c3c2)O1 |r| Show InChI InChI=1S/C32H29FN2O5S/c1-32(2)39-18-24(40-32)17-38-23-10-7-19-5-6-20-14-21(8-11-25(20)30(36)26(19)16-23)34-22-9-12-27(33)28(15-22)35-31(37)29-4-3-13-41-29/h3-4,7-16,24,34H,5-6,17-18H2,1-2H3,(H,35,37)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425348 (CHEMBL2316472) Show SMILES FCCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C24H19F3N2O2/c25-9-10-28-24(31)16-4-2-14-1-3-15-11-18(6-7-19(15)23(30)20(14)12-16)29-22-8-5-17(26)13-21(22)27/h2,4-8,11-13,29H,1,3,9-10H2,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425346 (CHEMBL2316479) Show SMILES OCC(O)CNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H22F2N2O4/c26-17-5-8-23(22(27)11-17)29-18-6-7-20-15(9-18)3-1-14-2-4-16(10-21(14)24(20)32)25(33)28-12-19(31)13-30/h2,4-11,19,29-31H,1,3,12-13H2,(H,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425345 (CHEMBL2316201) Show SMILES COC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H17F2NO3/c1-29-23(28)15-5-3-13-2-4-14-10-17(7-8-18(14)22(27)19(13)11-15)26-21-9-6-16(24)12-20(21)25/h3,5-12,26H,2,4H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425344 (CHEMBL2316205) Show SMILES OCCOC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C24H19F2NO4/c25-17-5-8-22(21(26)13-17)27-18-6-7-19-15(11-18)3-1-14-2-4-16(12-20(14)23(19)29)24(30)31-10-9-28/h2,4-8,11-13,27-28H,1,3,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425352 (CHEMBL2316486) Show SMILES OC[C@H](O)COc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5ccccc5)c4)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C31H27FN2O5/c32-28-13-10-23(15-29(28)34-31(38)20-4-2-1-3-5-20)33-22-9-12-26-21(14-22)7-6-19-8-11-25(16-27(19)30(26)37)39-18-24(36)17-35/h1-5,8-16,24,33,35-36H,6-7,17-18H2,(H,34,38)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) in presence of 300 uM ATP				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425338 (CHEMBL2316202) Show SMILES CCOC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C24H19F2NO3/c1-2-30-24(29)16-6-4-14-3-5-15-11-18(8-9-19(15)23(28)20(14)12-16)27-22-10-7-17(25)13-21(22)26/h4,6-13,27H,2-3,5H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425339 (CHEMBL2316481) Show SMILES CN(C)CCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C26H25F2N3O2/c1-31(2)12-11-29-26(33)18-6-4-16-3-5-17-13-20(8-9-21(17)25(32)22(16)14-18)30-24-10-7-19(27)15-23(24)28/h4,6-10,13-15,30H,3,5,11-12H2,1-2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425342 (CHEMBL2316473) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(cc4C3=O)C(=O)NCCCl)c2)c(F)c1 Show InChI InChI=1S/C24H19ClF2N2O2/c25-9-10-28-24(31)16-4-2-14-1-3-15-11-18(6-7-19(15)23(30)20(14)12-16)29-22-8-5-17(26)13-21(22)27/h2,4-8,11-13,29H,1,3,9-10H2,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425340 (CHEMBL2316477) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(cc4C3=O)C(=O)NCCN3CCOCC3)c2)c(F)c1 Show InChI InChI=1S/C28H27F2N3O3/c29-21-5-8-26(25(30)17-21)32-22-6-7-23-19(15-22)3-1-18-2-4-20(16-24(18)27(23)34)28(35)31-9-10-33-11-13-36-14-12-33/h2,4-8,15-17,32H,1,3,9-14H2,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425341 (CHEMBL2316476) Show SMILES CS(=O)(=O)CCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H22F2N2O4S/c1-34(32,33)11-10-28-25(31)17-5-3-15-2-4-16-12-19(7-8-20(16)24(30)21(15)13-17)29-23-9-6-18(26)14-22(23)27/h3,5-9,12-14,29H,2,4,10-11H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425343 (CHEMBL2316470) Show SMILES CNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H18F2N2O2/c1-26-23(29)15-5-3-13-2-4-14-10-17(7-8-18(14)22(28)19(13)11-15)27-21-9-6-16(24)12-20(21)25/h3,5-12,27H,2,4H2,1H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425369 (CHEMBL2316208) Show SMILES Fc1cc(F)c(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C28H20F2N2O2/c29-23-15-24(30)26(32-28(34)18-7-2-1-3-8-18)16-25(23)31-20-12-13-22-19(14-20)11-10-17-6-4-5-9-21(17)27(22)33/h1-9,12-16,31H,10-11H2,(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425379 (CHEMBL2316478) Show SMILES OCCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C24H20F2N2O3/c25-17-5-8-22(21(26)13-17)28-18-6-7-19-15(11-18)3-1-14-2-4-16(12-20(14)23(19)30)24(31)27-9-10-29/h2,4-8,11-13,28-29H,1,3,9-10H2,(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425375 (CHEMBL2316475) Show SMILES COCCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H22F2N2O3/c1-32-11-10-28-25(31)17-5-3-15-2-4-16-12-19(7-8-20(16)24(30)21(15)13-17)29-23-9-6-18(26)14-22(23)27/h3,5-9,12-14,29H,2,4,10-11H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392175 (CHEMBL2152944) Show SMILES OC[C@@H](O)COc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C24H21F2NO4/c25-16-4-8-23(22(26)10-16)27-17-5-7-20-15(9-17)2-1-14-3-6-19(11-21(14)24(20)30)31-13-18(29)12-28/h3-11,18,27-29H,1-2,12-13H2/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425382 (CHEMBL2316197) Show SMILES COC(=O)CC[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(=O)OC |r| Show InChI InChI=1S/C29H26F2N2O6/c1-38-26(34)12-11-25(29(37)39-2)33-28(36)18-6-4-16-3-5-17-13-20(8-9-21(17)27(35)22(16)14-18)32-24-10-7-19(30)15-23(24)31/h4,6-10,13-15,25,32H,3,5,11-12H2,1-2H3,(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425372 (CHEMBL2316196) Show SMILES CCOC(=O)CNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C26H22F2N2O4/c1-2-34-24(31)14-29-26(33)17-6-4-15-3-5-16-11-19(8-9-20(16)25(32)21(15)12-17)30-23-10-7-18(27)13-22(23)28/h4,6-13,30H,2-3,5,14H2,1H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425377 (CHEMBL2316493) Show SMILES OC[C@@H](O)COc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5cccs5)c4)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C29H25FN2O5S/c30-25-10-7-20(13-26(25)32-29(36)27-2-1-11-38-27)31-19-6-9-23-18(12-19)4-3-17-5-8-22(14-24(17)28(23)35)37-16-21(34)15-33/h1-2,5-14,21,31,33-34H,3-4,15-16H2,(H,32,36)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425367 (CHEMBL2316199) Show SMILES COC(=O)[C@H](CC(C)C)NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C29H28F2N2O4/c1-16(2)12-26(29(36)37-3)33-28(35)19-7-5-17-4-6-18-13-21(9-10-22(18)27(34)23(17)14-19)32-25-11-8-20(30)15-24(25)31/h5,7-11,13-16,26,32H,4,6,12H2,1-3H3,(H,33,35)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425370 (CHEMBL2316203) Show SMILES CCCOC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H21F2NO3/c1-2-11-31-25(30)17-6-4-15-3-5-16-12-19(8-9-20(16)24(29)21(15)13-17)28-23-10-7-18(26)14-22(23)27/h4,6-10,12-14,28H,2-3,5,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425383 (CHEMBL2316480) Show SMILES OCC(CO)NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H22F2N2O4/c26-17-5-8-23(22(27)11-17)28-18-6-7-20-15(9-18)3-1-14-2-4-16(10-21(14)24(20)32)25(33)29-19(12-30)13-31/h2,4-11,19,28,30-31H,1,3,12-13H2,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425381 (CHEMBL2316469) Show SMILES NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C22H16F2N2O2/c23-15-5-8-20(19(24)11-15)26-16-6-7-17-13(9-16)3-1-12-2-4-14(22(25)28)10-18(12)21(17)27/h2,4-11,26H,1,3H2,(H2,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425380 (CHEMBL2316195) Show SMILES CN1CCN(CCCNC(=O)c2ccc3CCc4cc(Nc5ccc(F)cc5F)ccc4C(=O)c3c2)CC1 Show InChI InChI=1S/C30H32F2N4O2/c1-35-13-15-36(16-14-35)12-2-11-33-30(38)22-6-4-20-3-5-21-17-24(8-9-25(21)29(37)26(20)18-22)34-28-10-7-23(31)19-27(28)32/h4,6-10,17-19,34H,2-3,5,11-16H2,1H3,(H,33,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425378 (CHEMBL2316194) Show SMILES CN1CCN(CCNC(=O)c2ccc3CCc4cc(Nc5ccc(F)cc5F)ccc4C(=O)c3c2)CC1 Show InChI InChI=1S/C29H30F2N4O2/c1-34-12-14-35(15-13-34)11-10-32-29(37)21-5-3-19-2-4-20-16-23(7-8-24(20)28(36)25(19)17-21)33-27-9-6-22(30)18-26(27)31/h3,5-9,16-18,33H,2,4,10-15H2,1H3,(H,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425366 (CHEMBL2316468) Show SMILES OC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C22H15F2NO3/c23-15-5-8-20(19(24)11-15)25-16-6-7-17-13(9-16)3-1-12-2-4-14(22(27)28)10-18(12)21(17)26/h2,4-11,25H,1,3H2,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425384 (CHEMBL2316466) Show SMILES Fc1cc(F)c(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C32H29F2N3O4S/c33-27-17-28(34)30(36-32(39)22-7-14-42-19-22)18-29(27)35-23-4-6-25-21(15-23)2-1-20-3-5-24(16-26(20)31(25)38)41-13-10-37-8-11-40-12-9-37/h3-7,14-19,35H,1-2,8-13H2,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425371 (CHEMBL2316496) Show SMILES Fc1cc(F)c(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)C1CCOC1 Show InChI InChI=1S/C32H33F2N3O5/c33-27-17-28(34)30(36-32(39)22-7-11-41-19-22)18-29(27)35-23-4-6-25-21(15-23)2-1-20-3-5-24(16-26(20)31(25)38)42-14-10-37-8-12-40-13-9-37/h3-6,15-18,22,35H,1-2,7-14,19H2,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425374 (CHEMBL2316198) Show SMILES CNC(=O)CC[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(=O)NC |r| Show InChI InChI=1S/C29H28F2N4O4/c1-32-26(36)12-11-25(29(39)33-2)35-28(38)18-6-4-16-3-5-17-13-20(8-9-21(17)27(37)22(16)14-18)34-24-10-7-19(30)15-23(24)31/h4,6-10,13-15,25,34H,3,5,11-12H2,1-2H3,(H,32,36)(H,33,39)(H,35,38)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425383 (CHEMBL2316480) Show SMILES OCC(CO)NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C25H22F2N2O4/c26-17-5-8-23(22(27)11-17)28-18-6-7-20-15(9-18)3-1-14-2-4-16(10-21(14)24(20)32)25(33)29-19(12-30)13-31/h2,4-11,19,28,30-31H,1,3,12-13H2,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425382 (CHEMBL2316197) Show SMILES COC(=O)CC[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(=O)OC |r| Show InChI InChI=1S/C29H26F2N2O6/c1-38-26(34)12-11-25(29(37)39-2)33-28(36)18-6-4-16-3-5-17-13-20(8-9-21(17)27(35)22(16)14-18)32-24-10-7-19(30)15-23(24)31/h4,6-10,13-15,25,32H,3,5,11-12H2,1-2H3,(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425339 (CHEMBL2316481) Show SMILES CN(C)CCNC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C26H25F2N3O2/c1-31(2)12-11-29-26(33)18-6-4-16-3-5-17-13-20(8-9-21(17)25(32)22(16)14-18)30-24-10-7-19(27)15-23(24)28/h4,6-10,13-15,30H,3,5,11-12H2,1-2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425380 (CHEMBL2316195) Show SMILES CN1CCN(CCCNC(=O)c2ccc3CCc4cc(Nc5ccc(F)cc5F)ccc4C(=O)c3c2)CC1 Show InChI InChI=1S/C30H32F2N4O2/c1-35-13-15-36(16-14-35)12-2-11-33-30(38)22-6-4-20-3-5-21-17-24(8-9-25(21)29(37)26(20)18-22)34-28-10-7-23(31)19-27(28)32/h4,6-10,17-19,34H,2-3,5,11-16H2,1H3,(H,33,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425381 (CHEMBL2316469) Show SMILES NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C22H16F2N2O2/c23-15-5-8-20(19(24)11-15)26-16-6-7-17-13(9-16)3-1-12-2-4-14(22(25)28)10-18(12)21(17)27/h2,4-11,26H,1,3H2,(H2,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425364 (CHEMBL2316487) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)C5CCOC5)c4)ccc3C(=O)c2c1 Show InChI InChI=1S/C28H27FN2O5/c29-25-8-5-21(14-26(25)31-28(34)19-9-11-35-16-19)30-20-4-7-23-18(13-20)2-1-17-3-6-22(36-12-10-32)15-24(17)27(23)33/h3-8,13-15,19,30,32H,1-2,9-12,16H2,(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425362 (CHEMBL2316482) Show SMILES COc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5ccccc5)c4)ccc3C(=O)c2c1 Show InChI InChI=1S/C29H23FN2O3/c1-35-23-12-9-18-7-8-20-15-21(10-13-24(20)28(33)25(18)17-23)31-22-11-14-26(30)27(16-22)32-29(34)19-5-3-2-4-6-19/h2-6,9-17,31H,7-8H2,1H3,(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
					More data for this Ligand-Target Pair

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