Found 21 hits Enz. Inhib. hit(s) with all data for entry = 50042566 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50396238
(CHEMBL2172212 | US9402842, 62)Show InChI InChI=1S/C19H17N3O2/c20-8-3-9-22-17-13-4-1-2-5-14(13)18(23)16(17)12-7-6-11(21)10-15(12)19(22)24/h1-2,4-7,10H,3,8-9,20-21H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427892
(CHEMBL2322286)Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccc(Br)cc2c1=O Show InChI InChI=1S/C21H19BrN2O2/c1-23(2)10-5-11-24-19-15-6-3-4-7-16(15)20(25)18(19)14-9-8-13(22)12-17(14)21(24)26/h3-4,6-9,12H,5,10-11H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.84E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50425045
(CHEMBL2312896 | CHEMBL2322964 | US9402842, 43)Show SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccc(NCC(O)=O)cc2c1=O Show InChI InChI=1S/C21H19N3O4/c22-8-3-9-24-19-14-4-1-2-5-15(14)20(27)18(19)13-7-6-12(23-11-17(25)26)10-16(13)21(24)28/h1-2,4-7,10,23H,3,8-9,11,22H2,(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50388545
(CHEMBL1181674 | CHEMBL188130)Show InChI InChI=1S/C18H14N2O2/c19-9-10-20-16-12-6-2-3-7-13(12)17(21)15(16)11-5-1-4-8-14(11)18(20)22/h1-8H,9-10,19H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50388546
(CHEMBL213072 | CHEMBL333363)Show InChI InChI=1S/C19H16N2O2/c20-10-5-11-21-17-13-7-2-3-8-14(13)18(22)16(17)12-6-1-4-9-15(12)19(21)23/h1-4,6-9H,5,10-11,20H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.66E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50388547
(CHEMBL1181663 | CHEMBL187863)Show InChI InChI=1S/C20H18N2O2/c21-11-5-6-12-22-18-14-8-2-3-9-15(14)19(23)17(18)13-7-1-4-10-16(13)20(22)24/h1-4,7-10H,5-6,11-12,21H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50388548
(CHEMBL1182248 | CHEMBL225093)Show InChI InChI=1S/C21H20N2O2/c22-12-6-1-7-13-23-19-15-9-3-4-10-16(15)20(24)18(19)14-8-2-5-11-17(14)21(23)25/h2-5,8-11H,1,6-7,12-13,22H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50388549
(CHEMBL1185123 | CHEMBL390611)Show InChI InChI=1S/C22H22N2O2/c23-13-7-1-2-8-14-24-20-16-10-4-5-11-17(16)21(25)19(20)15-9-3-6-12-18(15)22(24)26/h3-6,9-12H,1-2,7-8,13-14,23H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427893
(CHEMBL2322288)Show InChI InChI=1S/C20H17BrN2O2/c1-22-9-4-10-23-18-14-5-2-3-6-15(14)19(24)17(18)13-8-7-12(21)11-16(13)20(23)25/h2-3,5-8,11,22H,4,9-10H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427894
(CHEMBL425544)Show InChI InChI=1S/C21H20N2O2/c1-22(2)12-7-13-23-19-15-9-4-5-10-16(15)20(24)18(19)14-8-3-6-11-17(14)21(23)25/h3-6,8-11H,7,12-13H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427895
(CHEMBL2322955)Show InChI InChI=1S/C20H18N2O2/c1-21-11-6-12-22-18-14-8-3-4-9-15(14)19(23)17(18)13-7-2-5-10-16(13)20(22)24/h2-5,7-10,21H,6,11-12H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.22E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427896
(CHEMBL2326683)Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccc(N)cc2c1=O Show InChI InChI=1S/C21H21N3O2/c1-23(2)10-5-11-24-19-15-6-3-4-7-16(15)20(25)18(19)14-9-8-13(22)12-17(14)21(24)26/h3-4,6-9,12H,5,10-11,22H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50396236
(CHEMBL2172210)Show InChI InChI=1S/C20H19N3O2/c1-22-9-4-10-23-18-14-5-2-3-6-15(14)19(24)17(18)13-8-7-12(21)11-16(13)20(23)25/h2-3,5-8,11,22H,4,9-10,21H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50425054
(CHEMBL2312904)Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccc(cc2c1=O)C#N Show InChI InChI=1S/C22H19N3O2/c1-24(2)10-5-11-25-20-16-6-3-4-7-17(16)21(26)19(20)15-9-8-14(13-23)12-18(15)22(25)27/h3-4,6-9,12H,5,10-11H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.07E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50396234
(CHEMBL2172214 | US9402842, 57)Show SMILES CC(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1 Show InChI InChI=1S/C21H19N3O3/c1-12(25)23-13-7-8-14-17(11-13)21(27)24(10-4-9-22)19-15-5-2-3-6-16(15)20(26)18(14)19/h2-3,5-8,11H,4,9-10,22H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >3.47E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50396237
(CHEMBL2172208)Show InChI InChI=1S/C20H19N3O2/c1-22-12-7-8-13-16(11-12)20(25)23(10-4-9-21)18-14-5-2-3-6-15(14)19(24)17(13)18/h2-3,5-8,11,22H,4,9-10,21H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.22E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427897
(CHEMBL2324622)Show InChI InChI=1S/C19H19N3O/c20-8-3-9-22-18-14-5-2-1-4-12(14)10-16(18)15-7-6-13(21)11-17(15)19(22)23/h1-2,4-7,11H,3,8-10,20-21H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427898
(CHEMBL242857)Show SMILES COc1ccc-2c(c1)C(=O)c1c-2n(CCCN)c(=O)c2ccccc12 Show InChI InChI=1S/C20H18N2O3/c1-25-12-7-8-14-16(11-12)19(23)17-13-5-2-3-6-15(13)20(24)22(18(14)17)10-4-9-21/h2-3,5-8,11H,4,9-10,21H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.84E+3 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50032671
(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...)Show SMILES Cc1cc2c(cc1C1(CC1)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50427891
(CHEMBL2323836)Show SMILES COC(=O)c1ccc2c3C(=O)c4ccccc4-c3n(CCCN(C)C)c(=O)c2c1 Show InChI InChI=1S/C23H22N2O4/c1-24(2)11-6-12-25-20-16-7-4-5-8-17(16)21(26)19(20)15-10-9-14(23(28)29-3)13-18(15)22(25)27/h4-5,7-10,13H,6,11-12H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50425046
(CHEMBL2312571 | US9402842, 23)Show SMILES COC(=O)CC(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1 Show InChI InChI=1S/C23H21N3O5/c1-31-19(28)12-18(27)25-13-7-8-14-17(11-13)23(30)26(10-4-9-24)21-15-5-2-3-6-16(15)22(29)20(14)21/h2-3,5-8,11H,4,9-10,12,24H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >4.45E+4 | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay |
J Med Chem 56: 2581-605 (2013)
Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG |
More data for this
Ligand-Target Pair | |
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