Found 17 hits Enz. Inhib. hit(s) with all data for entry = 50042929 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H4 receptor
(Mus musculus (mouse)) | BDBM50433359
(CHEMBL2376804)Show InChI InChI=1S/C14H18N6/c1-16-10-6-20(7-10)13-12-11(18-14(15)19-13)4-9(5-17-12)8-2-3-8/h4-5,8,10,16H,2-3,6-7H2,1H3,(H2,15,18,19) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to mouse histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Mus musculus (mouse)) | BDBM50433358
(CHEMBL2376803)Show InChI InChI=1S/C16H22N6/c1-18-12-8-22(9-12)15-14-13(20-16(17)21-15)6-11(7-19-14)10-4-2-3-5-10/h6-7,10,12,18H,2-5,8-9H2,1H3,(H2,17,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to mouse histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50433358
(CHEMBL2376803)Show InChI InChI=1S/C16H22N6/c1-18-12-8-22(9-12)15-14-13(20-16(17)21-15)6-11(7-19-14)10-4-2-3-5-10/h6-7,10,12,18H,2-5,8-9H2,1H3,(H2,17,20,21) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to rat histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50433359
(CHEMBL2376804)Show InChI InChI=1S/C14H18N6/c1-16-10-6-20(7-10)13-12-11(18-14(15)19-13)4-9(5-17-12)8-2-3-8/h4-5,8,10,16H,2-3,6-7H2,1H3,(H2,15,18,19) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to rat histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Mus musculus (mouse)) | BDBM50433357
(CHEMBL2376800)Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to mouse histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50356884
(CHEMBL1915540)Show InChI InChI=1S/C13H22N6/c1-15-10-4-5-19(8-10)12-6-11(17-13(14)18-12)16-7-9-2-3-9/h6,9-10,15H,2-5,7-8H2,1H3,(H3,14,16,17,18)/t10-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to rat histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Mus musculus (mouse)) | BDBM50356884
(CHEMBL1915540)Show InChI InChI=1S/C13H22N6/c1-15-10-4-5-19(8-10)12-6-11(17-13(14)18-12)16-7-9-2-3-9/h6,9-10,15H,2-5,7-8H2,1H3,(H3,14,16,17,18)/t10-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to mouse histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50433357
(CHEMBL2376800)Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to rat histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Mus musculus (mouse)) | BDBM50433356
(CHEMBL2376801)Show InChI InChI=1S/C14H20N6/c1-3-9-6-11-12(17-7-9)13(19-14(15)18-11)20-5-4-10(8-20)16-2/h6-7,10,16H,3-5,8H2,1-2H3,(H2,15,18,19)/t10-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to mouse histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50433356
(CHEMBL2376801)Show InChI InChI=1S/C14H20N6/c1-3-9-6-11-12(17-7-9)13(19-14(15)18-11)20-5-4-10(8-20)16-2/h6-7,10,16H,3-5,8H2,1-2H3,(H2,15,18,19)/t10-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 138 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Binding affinity to rat histamine H4 receptor |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50433358
(CHEMBL2376803)Show InChI InChI=1S/C16H22N6/c1-18-12-8-22(9-12)15-14-13(20-16(17)21-15)6-11(7-19-14)10-4-2-3-5-10/h6-7,10,12,18H,2-5,8-9H2,1H3,(H2,17,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H2 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50433356
(CHEMBL2376801)Show InChI InChI=1S/C14H20N6/c1-3-9-6-11-12(17-7-9)13(19-14(15)18-11)20-5-4-10(8-20)16-2/h6-7,10,16H,3-5,8H2,1-2H3,(H2,15,18,19)/t10-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H2 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50433356
(CHEMBL2376801)Show InChI InChI=1S/C14H20N6/c1-3-9-6-11-12(17-7-9)13(19-14(15)18-11)20-5-4-10(8-20)16-2/h6-7,10,16H,3-5,8H2,1-2H3,(H2,15,18,19)/t10-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H1 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50433357
(CHEMBL2376800)Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H2 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50433358
(CHEMBL2376803)Show InChI InChI=1S/C16H22N6/c1-18-12-8-22(9-12)15-14-13(20-16(17)21-15)6-11(7-19-14)10-4-2-3-5-10/h6-7,10,12,18H,2-5,8-9H2,1H3,(H2,17,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H1 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50433359
(CHEMBL2376804)Show InChI InChI=1S/C14H18N6/c1-16-10-6-20(7-10)13-12-11(18-14(15)19-13)4-9(5-17-12)8-2-3-8/h4-5,8,10,16H,2-3,6-7H2,1H3,(H2,15,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H1 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50433357
(CHEMBL2376800)Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description Displacement of [3H]histamine from human histamine H1 receptor expressed in HEK cells |
Bioorg Med Chem Lett 23: 2663-70 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11 |
More data for this Ligand-Target Pair | |