Compile Data Set for Download or QSAR

Found 54 hits Enz. Inhib. hit(s) with all data for entry = 50043326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439402 (CHEMBL2420537) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccccc2Br)ccc1C Show InChI InChI=1S/C17H19BrN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439424 (CHEMBL2420540) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)ccc1C Show InChI InChI=1S/C16H19N3O3S/c1-12-9-10-14(11-15(12)23(21,22)19(2)3)18-16(20)17-13-7-5-4-6-8-13/h4-11H,1-3H3,(H2,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50437983 (CHEMBL2409106) Show SMILES Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1 Show InChI InChI=1S/C17H14F2N4O/c1-11-9-16(23(22-11)13-5-3-2-4-6-13)21-17(24)20-12-7-8-14(18)15(19)10-12/h2-10H,1H3,(H2,20,21,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50115223 (1-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-3-phenyl-ure...) Show SMILES Cc1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C17H16N4O/c1-13-12-16(21(20-13)15-10-6-3-7-11-15)19-17(22)18-14-8-4-2-5-9-14/h2-12H,1H3,(H2,18,19,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439404 (CHEMBL2420539) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2)ccc1C Show InChI InChI=1S/C17H19FN2O3S/c1-12-4-9-15(11-16(12)24(22,23)20(2)3)19-17(21)10-13-5-7-14(18)8-6-13/h4-9,11H,10H2,1-3H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM95731 (2-(4-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]...) Show SMILES CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C16H17ClN2O3S/c1-19(2)23(21,22)15-5-3-4-14(11-15)18-16(20)10-12-6-8-13(17)9-7-12/h3-9,11H,10H2,1-2H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439405 (CHEMBL2420538) Show SMILES CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C16H17ClN2O3S/c1-19(2)23(21,22)14-8-5-7-13(11-14)18-16(20)10-12-6-3-4-9-15(12)17/h3-9,11H,10H2,1-2H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439402 (CHEMBL2420537) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccccc2Br)ccc1C Show InChI InChI=1S/C17H19BrN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439403 (CHEMBL1558022) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1C Show InChI InChI=1S/C17H19ClN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50437983 (CHEMBL2409106) Show SMILES Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1 Show InChI InChI=1S/C17H14F2N4O/c1-11-9-16(23(22-11)13-5-3-2-4-6-13)21-17(24)20-12-7-8-14(18)15(19)10-12/h2-10H,1H3,(H2,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50115223 (1-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-3-phenyl-ure...) Show SMILES Cc1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C17H16N4O/c1-13-12-16(21(20-13)15-10-6-3-7-11-15)19-17(22)18-14-8-4-2-5-9-14/h2-12H,1H3,(H2,18,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50241582 ((S)-7-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxyme...) Show SMILES C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of recombinant human GIRK1/4 expressed in Xenopus oocytes by two-electrode voltage clamp method				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50241582 ((S)-7-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxyme...) Show SMILES C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of recombinant human GIRK1/2 expressed in Xenopus oocytes by two-electrode voltage clamp method				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439404 (CHEMBL2420539) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2)ccc1C Show InChI InChI=1S/C17H19FN2O3S/c1-12-4-9-15(11-16(12)24(22,23)20(2)3)19-17(21)10-13-5-7-14(18)8-6-13/h4-9,11H,10H2,1-3H3,(H,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM95731 (2-(4-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]...) Show SMILES CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C16H17ClN2O3S/c1-19(2)23(21,22)15-5-3-4-14(11-15)18-16(20)10-12-6-8-13(17)9-7-12/h3-9,11H,10H2,1-2H3,(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439405 (CHEMBL2420538) Show SMILES CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C16H17ClN2O3S/c1-19(2)23(21,22)14-8-5-7-13(11-14)18-16(20)10-12-6-3-4-9-15(12)17/h3-9,11H,10H2,1-2H3,(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439406 (CHEMBL2420536) Show SMILES Cc1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C15H14ClNO/c1-11-5-4-7-13(9-11)17-15(18)10-12-6-2-3-8-14(12)16/h2-9H,10H2,1H3,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439407 (CHEMBL2420535) Show SMILES FC(F)(F)c1ccc(NC(=O)Cc2ccccc2Cl)cc1 Show InChI InChI=1S/C15H11ClF3NO/c16-13-4-2-1-3-10(13)9-14(21)20-12-7-5-11(6-8-12)15(17,18)19/h1-8H,9H2,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439408 (CHEMBL2420534) Show SMILES Clc1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C14H11Cl2NO/c15-11-5-3-6-12(9-11)17-14(18)8-10-4-1-2-7-13(10)16/h1-7,9H,8H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439409 (CHEMBL2420533) Show SMILES Clc1ccc(NC(=O)Cc2ccccc2Cl)cc1 Show InChI InChI=1S/C14H11Cl2NO/c15-11-5-7-12(8-6-11)17-14(18)9-10-3-1-2-4-13(10)16/h1-8H,9H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439410 (CHEMBL2420532) Show SMILES FC(F)(F)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Cl Show InChI InChI=1S/C15H10Cl2F3NO/c16-12-4-2-1-3-9(12)7-14(22)21-10-5-6-13(17)11(8-10)15(18,19)20/h1-6,8H,7H2,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439411 (CHEMBL2420531) Show SMILES FC(F)(F)c1cc(Cl)cc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C15H10Cl2F3NO/c16-11-6-10(15(18,19)20)7-12(8-11)21-14(22)5-9-3-1-2-4-13(9)17/h1-4,6-8H,5H2,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439412 (CHEMBL2420530) Show SMILES FC(F)Oc1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C15H12ClF2NO2/c16-13-7-2-1-4-10(13)8-14(20)19-11-5-3-6-12(9-11)21-15(17)18/h1-7,9,15H,8H2,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439413 (CHEMBL2420529) Show SMILES CC(C)(C)c1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C18H20ClNO/c1-18(2,3)14-8-6-9-15(12-14)20-17(21)11-13-7-4-5-10-16(13)19/h4-10,12H,11H2,1-3H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439414 (CHEMBL2420550) Show SMILES CS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1F Show InChI InChI=1S/C15H13ClFNO3S/c1-22(20,21)14-9-11(6-7-13(14)17)18-15(19)8-10-4-2-3-5-12(10)16/h2-7,9H,8H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439415 (CHEMBL2420549) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2cccc(c2)C#N)ccc1C Show InChI InChI=1S/C17H18N4O3S/c1-12-7-8-15(10-16(12)25(23,24)21(2)3)20-17(22)19-14-6-4-5-13(9-14)11-18/h4-10H,1-3H3,(H2,19,20,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439416 (CHEMBL2420548) Show SMILES COc1ccc(OC)c(NC(=O)Nc2ccc(C)c(c2)S(=O)(=O)N(C)C)c1 Show InChI InChI=1S/C18H23N3O5S/c1-12-6-7-13(10-17(12)27(23,24)21(2)3)19-18(22)20-15-11-14(25-4)8-9-16(15)26-5/h6-11H,1-5H3,(H2,19,20,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439417 (CHEMBL2420547) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccc(cc2)C(F)(F)F)ccc1C Show InChI InChI=1S/C17H18F3N3O3S/c1-11-4-7-14(10-15(11)27(25,26)23(2)3)22-16(24)21-13-8-5-12(6-9-13)17(18,19)20/h4-10H,1-3H3,(H2,21,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439418 (CHEMBL2420546) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2Cl)ccc1C Show InChI InChI=1S/C16H18ClN3O3S/c1-11-8-9-12(10-15(11)24(22,23)20(2)3)18-16(21)19-14-7-5-4-6-13(14)17/h4-10H,1-3H3,(H2,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439419 (CHEMBL2420545) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2cccc(F)c2)ccc1C Show InChI InChI=1S/C16H18FN3O3S/c1-11-7-8-14(10-15(11)24(22,23)20(2)3)19-16(21)18-13-6-4-5-12(17)9-13/h4-10H,1-3H3,(H2,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439420 (CHEMBL2420544) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2F)ccc1C Show InChI InChI=1S/C16H18FN3O3S/c1-11-8-9-12(10-15(11)24(22,23)20(2)3)18-16(21)19-14-7-5-4-6-13(14)17/h4-10H,1-3H3,(H2,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439421 (CHEMBL2420543) Show SMILES COc1ccc(NC(=O)Nc2ccc(C)c(c2)S(=O)(=O)N(C)C)cc1 Show InChI InChI=1S/C17H21N3O4S/c1-12-5-6-14(11-16(12)25(22,23)20(2)3)19-17(21)18-13-7-9-15(24-4)10-8-13/h5-11H,1-4H3,(H2,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439422 (CHEMBL2420542) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccc(C)c(Cl)c2)ccc1C Show InChI InChI=1S/C17H20ClN3O3S/c1-11-5-7-13(9-15(11)18)19-17(22)20-14-8-6-12(2)16(10-14)25(23,24)21(3)4/h5-10H,1-4H3,(H2,19,20,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439423 (CHEMBL2420541) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1C Show InChI InChI=1S/C16H18ClN3O3S/c1-11-4-7-14(10-15(11)24(22,23)20(2)3)19-16(21)18-13-8-5-12(17)6-9-13/h4-10H,1-3H3,(H2,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439424 (CHEMBL2420540) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)ccc1C Show InChI InChI=1S/C16H19N3O3S/c1-12-9-10-14(11-15(12)23(21,22)19(2)3)18-16(20)17-13-7-5-4-6-8-13/h4-11H,1-3H3,(H2,17,18,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439406 (CHEMBL2420536) Show SMILES Cc1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C15H14ClNO/c1-11-5-4-7-13(9-11)17-15(18)10-12-6-2-3-8-14(12)16/h2-9H,10H2,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439407 (CHEMBL2420535) Show SMILES FC(F)(F)c1ccc(NC(=O)Cc2ccccc2Cl)cc1 Show InChI InChI=1S/C15H11ClF3NO/c16-13-4-2-1-3-10(13)9-14(21)20-12-7-5-11(6-8-12)15(17,18)19/h1-8H,9H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439408 (CHEMBL2420534) Show SMILES Clc1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C14H11Cl2NO/c15-11-5-3-6-12(9-11)17-14(18)8-10-4-1-2-7-13(10)16/h1-7,9H,8H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439409 (CHEMBL2420533) Show SMILES Clc1ccc(NC(=O)Cc2ccccc2Cl)cc1 Show InChI InChI=1S/C14H11Cl2NO/c15-11-5-7-12(8-6-11)17-14(18)9-10-3-1-2-4-13(10)16/h1-8H,9H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439410 (CHEMBL2420532) Show SMILES FC(F)(F)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Cl Show InChI InChI=1S/C15H10Cl2F3NO/c16-12-4-2-1-3-9(12)7-14(22)21-10-5-6-13(17)11(8-10)15(18,19)20/h1-6,8H,7H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439411 (CHEMBL2420531) Show SMILES FC(F)(F)c1cc(Cl)cc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C15H10Cl2F3NO/c16-11-6-10(15(18,19)20)7-12(8-11)21-14(22)5-9-3-1-2-4-13(9)17/h1-4,6-8H,5H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439412 (CHEMBL2420530) Show SMILES FC(F)Oc1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C15H12ClF2NO2/c16-13-7-2-1-4-10(13)8-14(20)19-11-5-3-6-12(9-11)21-15(17)18/h1-7,9,15H,8H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439413 (CHEMBL2420529) Show SMILES CC(C)(C)c1cccc(NC(=O)Cc2ccccc2Cl)c1 Show InChI InChI=1S/C18H20ClNO/c1-18(2,3)14-8-6-9-15(12-14)20-17(21)11-13-7-4-5-10-16(13)19/h4-10,12H,11H2,1-3H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439414 (CHEMBL2420550) Show SMILES CS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1F Show InChI InChI=1S/C15H13ClFNO3S/c1-22(20,21)14-9-11(6-7-13(14)17)18-15(19)8-10-4-2-3-5-12(10)16/h2-7,9H,8H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439415 (CHEMBL2420549) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2cccc(c2)C#N)ccc1C Show InChI InChI=1S/C17H18N4O3S/c1-12-7-8-15(10-16(12)25(23,24)21(2)3)20-17(22)19-14-6-4-5-13(9-14)11-18/h4-10H,1-3H3,(H2,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439416 (CHEMBL2420548) Show SMILES COc1ccc(OC)c(NC(=O)Nc2ccc(C)c(c2)S(=O)(=O)N(C)C)c1 Show InChI InChI=1S/C18H23N3O5S/c1-12-6-7-13(10-17(12)27(23,24)21(2)3)19-18(22)20-15-11-14(25-4)8-9-16(15)26-5/h6-11H,1-5H3,(H2,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439417 (CHEMBL2420547) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccc(cc2)C(F)(F)F)ccc1C Show InChI InChI=1S/C17H18F3N3O3S/c1-11-4-7-14(10-15(11)27(25,26)23(2)3)22-16(24)21-13-8-5-12(6-9-13)17(18,19)20/h4-10H,1-3H3,(H2,21,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439418 (CHEMBL2420546) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2Cl)ccc1C Show InChI InChI=1S/C16H18ClN3O3S/c1-11-8-9-12(10-15(11)24(22,23)20(2)3)18-16(21)19-14-7-5-4-6-13(14)17/h4-10H,1-3H3,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439419 (CHEMBL2420545) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2cccc(F)c2)ccc1C Show InChI InChI=1S/C16H18FN3O3S/c1-11-7-8-14(10-15(11)24(22,23)20(2)3)19-16(21)18-13-6-4-5-12(17)9-13/h4-10H,1-3H3,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439420 (CHEMBL2420544) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2F)ccc1C Show InChI InChI=1S/C16H18FN3O3S/c1-11-8-9-12(10-15(11)24(22,23)20(2)3)18-16(21)19-14-7-5-4-6-13(14)17/h4-10H,1-3H3,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair

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