Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Mus musculus) | BDBM35909 (2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Mus musculus) | BDBM50442124 (CHEMBL2441094) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442125 (CHEMBL2441107) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442123 (CHEMBL2441092) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442131 (CHEMBL2441100) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50442123 (CHEMBL2441092) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil... | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442121 (CHEMBL2441091) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442130 (CHEMBL2441098) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM35909 (2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil... | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Mus musculus) | BDBM50442122 (CHEMBL2441093) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442129 (CHEMBL2441099) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442135 (CHEMBL2441105) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50442124 (CHEMBL2441094) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil... | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442138 (CHEMBL2441110) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442128 (CHEMBL2441097) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442126 (CHEMBL2441096) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442132 (CHEMBL2441101) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442133 (CHEMBL2441103) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442134 (CHEMBL2441102) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50442121 (CHEMBL2441091) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil... | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442136 (CHEMBL2441108) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50442122 (CHEMBL2441093) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil... | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442137 (CHEMBL2441109) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Mus musculus) | BDBM50442127 (CHEMBL2441095) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50442125 (CHEMBL2441107) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil... | ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4 | |||||||||||
More data for this Ligand-Target Pair |