Compile Data Set for Download or QSAR

Found 135 hits Enz. Inhib. hit(s) with all data for entry = 50043643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444072 (CHEMBL3092793) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C(=O)NC1CCN(C)CC1 |r,wU:11.10,wD:14.14,(42.31,-47.3,;43.64,-46.53,;44.98,-47.3,;46.31,-46.53,;47.64,-47.3,;48.98,-46.53,;50.31,-47.3,;51.65,-46.53,;51.65,-44.98,;50.31,-44.22,;50.31,-42.68,;48.97,-41.91,;47.64,-42.68,;46.31,-41.91,;46.31,-40.36,;44.97,-39.59,;47.64,-39.6,;48.97,-40.36,;48.98,-44.99,;52.98,-44.2,;54.31,-44.98,;55.64,-44.2,;55.63,-42.66,;54.29,-41.9,;52.96,-42.67,;56.96,-41.88,;56.95,-40.34,;58.3,-42.65,;59.63,-41.87,;60.96,-42.64,;62.29,-41.87,;62.29,-40.33,;63.62,-39.56,;60.95,-39.56,;59.61,-40.34,)| Show InChI InChI=1S/C26H39N7O2/c1-3-4-13-27-26-29-17-22(24(32-26)30-19-6-8-21(34)9-7-19)23-10-5-18(16-28-23)25(35)31-20-11-14-33(2)15-12-20/h5,10,16-17,19-21,34H,3-4,6-9,11-15H2,1-2H3,(H,31,35)(H2,27,29,30,32)/t19-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444070 (CHEMBL3092795) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNC2CCCCC2)cn1 |r,wU:11.10,wD:14.14,(-.85,-56.03,;.49,-55.27,;1.83,-56.04,;3.16,-55.27,;4.49,-56.04,;5.83,-55.27,;7.16,-56.04,;8.5,-55.27,;8.49,-53.72,;7.16,-52.95,;7.15,-51.42,;5.82,-50.65,;4.49,-51.42,;3.16,-50.65,;3.15,-49.1,;1.82,-48.33,;4.49,-48.34,;5.82,-49.1,;5.83,-53.73,;9.83,-52.94,;11.16,-53.71,;12.49,-52.94,;12.48,-51.4,;13.81,-50.62,;15.15,-51.39,;16.48,-50.61,;17.81,-51.38,;19.14,-50.61,;19.14,-49.07,;17.8,-48.3,;16.46,-49.08,;11.14,-50.63,;9.81,-51.41,)| Show InChI InChI=1S/C26H40N6O/c1-2-3-15-27-26-30-18-23(25(32-26)31-21-10-12-22(33)13-11-21)24-14-9-19(17-29-24)16-28-20-7-5-4-6-8-20/h9,14,17-18,20-22,28,33H,2-8,10-13,15-16H2,1H3,(H2,27,30,31,32)/t21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444073 (CHEMBL3092792) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)S(=O)(=O)N1CCOCC1 |r,wU:11.10,wD:14.14,(17.06,-43.23,;18.4,-42.47,;19.73,-43.24,;21.06,-42.47,;22.4,-43.24,;23.73,-42.47,;25.07,-43.24,;26.4,-42.47,;26.4,-40.92,;25.06,-40.15,;25.06,-38.61,;23.72,-37.85,;22.4,-38.62,;21.06,-37.85,;21.06,-36.3,;19.73,-35.53,;22.39,-35.54,;23.72,-36.3,;23.73,-40.93,;27.73,-40.14,;29.06,-40.91,;30.39,-40.14,;30.39,-38.6,;29.04,-37.83,;27.72,-38.61,;31.72,-37.82,;32.48,-36.48,;30.94,-36.49,;33.05,-38.59,;33.05,-40.13,;34.38,-40.89,;35.71,-40.12,;35.71,-38.58,;34.37,-37.81,)| Show InChI InChI=1S/C23H34N6O4S/c1-2-3-10-24-23-26-16-20(22(28-23)27-17-4-6-18(30)7-5-17)21-9-8-19(15-25-21)34(31,32)29-11-13-33-14-12-29/h8-9,15-18,30H,2-7,10-14H2,1H3,(H2,24,26,27,28)/t17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444068 (CHEMBL3092797) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNCCO)cn1 |r,wU:11.10,wD:14.14,(43.3,-58.78,;44.63,-58.01,;45.97,-58.78,;47.3,-58.01,;48.63,-58.78,;49.97,-58.01,;51.3,-58.78,;52.64,-58.01,;52.63,-56.46,;51.3,-55.7,;51.29,-54.16,;49.96,-53.39,;48.63,-54.16,;47.29,-53.39,;47.29,-51.84,;45.96,-51.07,;48.63,-51.08,;49.96,-51.84,;49.97,-56.47,;53.96,-55.68,;55.3,-56.46,;56.63,-55.68,;56.62,-54.14,;57.95,-53.36,;59.29,-54.13,;60.62,-53.35,;61.96,-54.11,;63.28,-53.34,;55.27,-53.38,;53.95,-54.15,)| Show InChI InChI=1S/C22H34N6O2/c1-2-3-10-24-22-26-15-19(20-9-4-16(14-25-20)13-23-11-12-29)21(28-22)27-17-5-7-18(30)8-6-17/h4,9,14-15,17-18,23,29-30H,2-3,5-8,10-13H2,1H3,(H2,24,26,27,28)/t17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444075 (CHEMBL3092790) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCC(F)(F)CC2)cn1 |r,wU:11.10,wD:14.14,(52.92,-33.3,;54.26,-32.53,;55.59,-33.3,;56.93,-32.54,;58.26,-33.31,;59.59,-32.54,;60.93,-33.31,;62.26,-32.54,;62.26,-30.99,;60.92,-30.22,;60.92,-28.68,;59.58,-27.92,;58.26,-28.69,;56.92,-27.91,;56.92,-26.37,;55.59,-25.6,;58.26,-25.6,;59.58,-26.37,;59.6,-30.99,;63.59,-30.21,;64.92,-30.98,;66.25,-30.21,;66.25,-28.67,;67.58,-27.89,;68.91,-28.65,;68.91,-30.19,;70.24,-30.96,;71.58,-30.19,;72.35,-31.52,;73.12,-30.18,;71.57,-28.64,;70.23,-27.87,;64.9,-27.9,;63.58,-28.68,)| Show InChI InChI=1S/C25H36F2N6O/c1-2-3-12-28-24-30-16-21(23(32-24)31-19-5-7-20(34)8-6-19)22-9-4-18(15-29-22)17-33-13-10-25(26,27)11-14-33/h4,9,15-16,19-20,34H,2-3,5-8,10-14,17H2,1H3,(H2,28,30,31,32)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444069 (CHEMBL3092796) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNC2CC2)cn1 |r,wU:11.10,wD:14.14,(20.96,-58.36,;22.3,-57.6,;23.63,-58.37,;24.96,-57.6,;26.3,-58.37,;27.63,-57.6,;28.96,-58.37,;30.3,-57.6,;30.3,-56.05,;28.96,-55.28,;28.96,-53.74,;27.62,-52.98,;26.29,-53.75,;24.96,-52.98,;24.96,-51.43,;23.62,-50.66,;26.29,-50.67,;27.62,-51.43,;27.63,-56.06,;31.63,-55.27,;32.96,-56.04,;34.29,-55.27,;34.28,-53.73,;35.61,-52.95,;36.95,-53.72,;38.28,-52.94,;39.81,-52.93,;39.04,-51.6,;32.94,-52.96,;31.61,-53.74,)| Show InChI InChI=1S/C23H34N6O/c1-2-3-12-24-23-27-15-20(22(29-23)28-18-7-9-19(30)10-8-18)21-11-4-16(14-26-21)13-25-17-5-6-17/h4,11,14-15,17-19,25,30H,2-3,5-10,12-13H2,1H3,(H2,24,27,28,29)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444042 (CHEMBL3092807) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCOCC2)cn1 |r,wU:11.10,wD:14.14,(58.28,-22.87,;59.62,-22.1,;60.95,-22.87,;62.28,-22.11,;63.62,-22.88,;64.95,-22.11,;66.29,-22.88,;67.62,-22.11,;67.62,-20.56,;66.28,-19.79,;66.28,-18.25,;64.94,-17.49,;63.62,-18.26,;62.28,-17.48,;62.28,-15.94,;60.94,-15.17,;63.61,-15.17,;64.94,-15.94,;64.95,-20.56,;68.95,-19.78,;70.28,-20.55,;71.61,-19.78,;71.6,-18.24,;72.93,-17.46,;74.27,-18.22,;74.27,-19.76,;75.6,-20.53,;76.93,-19.76,;76.93,-18.21,;75.59,-17.44,;70.26,-17.47,;68.93,-18.25,)| Show InChI InChI=1S/C24H36N6O2/c1-2-3-10-25-24-27-16-21(23(29-24)28-19-5-7-20(31)8-6-19)22-9-4-18(15-26-22)17-30-11-13-32-14-12-30/h4,9,15-16,19-20,31H,2-3,5-8,10-14,17H2,1H3,(H2,25,27,28,29)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444074 (CHEMBL3092791) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN(C)C)cn1 |r,wU:11.10,wD:14.14,(-4.06,-43.37,;-2.72,-42.6,;-1.39,-43.37,;-.05,-42.6,;1.29,-43.37,;2.62,-42.6,;3.96,-43.37,;5.29,-42.6,;5.29,-41.05,;3.95,-40.29,;3.95,-38.75,;2.61,-37.98,;1.29,-38.75,;-.06,-37.98,;-.06,-36.44,;-1.39,-35.67,;1.29,-35.67,;2.61,-36.44,;2.63,-41.06,;6.62,-40.28,;7.95,-41.05,;9.28,-40.27,;9.27,-38.73,;10.6,-37.96,;11.94,-38.72,;13.26,-37.94,;11.95,-40.26,;7.93,-37.97,;6.6,-38.75,)| Show InChI InChI=1S/C22H34N6O/c1-4-5-12-23-22-25-14-19(20-11-6-16(13-24-20)15-28(2)3)21(27-22)26-17-7-9-18(29)10-8-17/h6,11,13-14,17-18,29H,4-5,7-10,12,15H2,1-3H3,(H2,23,25,26,27)/t17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444066 (CHEMBL3092799) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.98,-7.45,;17.32,-6.68,;18.65,-7.45,;19.98,-6.68,;21.32,-7.45,;22.65,-6.69,;23.98,-7.46,;25.32,-6.68,;25.32,-5.13,;23.98,-4.37,;23.98,-2.83,;22.64,-2.06,;21.31,-2.84,;19.98,-2.06,;19.98,-.52,;18.64,.26,;21.31,.25,;22.64,-.52,;22.65,-5.14,;26.65,-4.36,;27.98,-5.13,;29.31,-4.36,;29.3,-2.81,;27.96,-2.05,;26.64,-2.82,)| Show InChI InChI=1S/C19H28N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-6,12-15H,2-3,7-11,20H2,1H3,(H2,22,23,24,25)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444080 (CHEMBL3092805) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)N1CCN(C)CC1 |r,wU:11.10,wD:14.14,(13.34,-23.32,;14.67,-22.55,;16,-23.32,;17.34,-22.56,;18.67,-23.33,;20.01,-22.56,;21.34,-23.33,;22.68,-22.56,;22.67,-21.01,;21.34,-20.24,;21.33,-18.7,;20,-17.94,;18.67,-18.71,;17.33,-17.93,;17.33,-16.39,;16,-15.62,;18.67,-15.62,;20,-16.39,;20.01,-21.01,;24,-20.23,;25.33,-21,;26.66,-20.23,;26.66,-18.69,;25.31,-17.92,;23.99,-18.7,;27.99,-17.91,;29.31,-18.68,;30.64,-17.91,;30.64,-16.37,;31.97,-15.6,;29.3,-15.6,;27.97,-16.37,)| Show InChI InChI=1S/C24H37N7O/c1-3-4-11-25-24-27-17-21(23(29-24)28-18-5-8-20(32)9-6-18)22-10-7-19(16-26-22)31-14-12-30(2)13-15-31/h7,10,16-18,20,32H,3-6,8-9,11-15H2,1-2H3,(H2,25,27,28,29)/t18-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444071 (CHEMBL3092794) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(NC(=O)C2CCN(C)CC2)cn1 |r,wU:11.10,wD:14.14,(41.44,-46.25,;42.77,-45.48,;44.11,-46.25,;45.44,-45.48,;46.77,-46.25,;48.11,-45.48,;49.44,-46.25,;50.78,-45.48,;50.78,-43.93,;49.44,-43.17,;49.44,-41.63,;48.1,-40.86,;46.77,-41.63,;45.44,-40.86,;45.44,-39.32,;44.1,-38.54,;46.77,-38.55,;48.1,-39.31,;48.11,-43.94,;52.11,-43.16,;53.44,-43.93,;54.77,-43.15,;54.76,-41.61,;56.09,-40.83,;57.43,-41.6,;57.44,-43.14,;58.76,-40.82,;60.09,-41.59,;61.42,-40.82,;61.42,-39.28,;62.75,-38.51,;60.08,-38.51,;58.74,-39.29,;53.42,-40.85,;52.09,-41.62,)| Show InChI InChI=1S/C26H39N7O2/c1-3-4-13-27-26-29-17-22(24(32-26)30-19-5-8-21(34)9-6-19)23-10-7-20(16-28-23)31-25(35)18-11-14-33(2)15-12-18/h7,10,16-19,21,34H,3-6,8-9,11-15H2,1-2H3,(H,31,35)(H2,27,29,30,32)/t19-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444079 (CHEMBL3092806) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCN(C)CC2)cn1 |r,wU:11.10,wD:14.14,(37.6,-21.62,;38.94,-20.85,;40.27,-21.62,;41.6,-20.85,;42.94,-21.62,;44.27,-20.86,;45.61,-21.63,;46.94,-20.85,;46.94,-19.3,;45.6,-18.54,;45.6,-17,;44.26,-16.23,;42.94,-17.01,;41.6,-16.23,;41.6,-14.69,;40.26,-13.92,;42.93,-13.92,;44.26,-14.69,;44.27,-19.31,;48.27,-18.53,;49.6,-19.3,;50.93,-18.53,;50.92,-16.98,;52.25,-16.21,;53.59,-16.97,;53.59,-18.51,;54.92,-19.27,;56.25,-18.5,;57.59,-19.27,;56.25,-16.96,;54.91,-16.19,;49.58,-16.22,;48.25,-17,)| Show InChI InChI=1S/C25H39N7O/c1-3-4-11-26-25-28-17-22(24(30-25)29-20-6-8-21(33)9-7-20)23-10-5-19(16-27-23)18-32-14-12-31(2)13-15-32/h5,10,16-17,20-21,33H,3-4,6-9,11-15,18H2,1-2H3,(H2,26,28,29,30)/t20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444065 (CHEMBL3092800) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](CN)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(31.68,-9.79,;33.01,-9.02,;34.35,-9.79,;35.68,-9.02,;37.01,-9.8,;38.35,-9.03,;39.68,-9.8,;41.02,-9.03,;41.01,-7.48,;39.68,-6.71,;39.67,-5.17,;38.34,-4.41,;37.01,-5.18,;35.67,-4.4,;35.67,-2.86,;34.34,-2.09,;34.34,-.55,;37.01,-2.09,;38.34,-2.86,;38.35,-7.48,;42.34,-6.7,;43.68,-7.47,;45,-6.7,;45,-5.16,;43.65,-4.39,;42.34,-5.16,)| Show InChI InChI=1S/C20H30N6/c1-2-3-11-23-20-24-14-17(18-6-4-5-12-22-18)19(26-20)25-16-9-7-15(13-21)8-10-16/h4-6,12,14-16H,2-3,7-11,13,21H2,1H3,(H2,23,24,25,26)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444081 (CHEMBL3092804) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(F)cn1 |r,wU:11.10,wD:14.14,(-.58,-23.28,;.77,-22.52,;2.11,-23.29,;3.44,-22.52,;4.77,-23.29,;6.11,-22.52,;7.44,-23.29,;8.78,-22.52,;8.77,-20.97,;7.44,-20.2,;7.43,-18.66,;6.1,-17.9,;4.77,-18.67,;3.44,-17.9,;3.43,-16.35,;2.1,-15.58,;4.77,-15.59,;6.1,-16.35,;6.11,-20.98,;10.11,-20.19,;11.44,-20.96,;12.77,-20.19,;12.76,-18.65,;14.09,-17.87,;11.42,-17.88,;10.09,-18.66,)| Show InChI InChI=1S/C19H26FN5O/c1-2-3-10-21-19-23-12-16(17-9-4-13(20)11-22-17)18(25-19)24-14-5-7-15(26)8-6-14/h4,9,11-12,14-15,26H,2-3,5-8,10H2,1H3,(H2,21,23,24,25)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444042 (CHEMBL3092807) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCOCC2)cn1 |r,wU:11.10,wD:14.14,(58.28,-22.87,;59.62,-22.1,;60.95,-22.87,;62.28,-22.11,;63.62,-22.88,;64.95,-22.11,;66.29,-22.88,;67.62,-22.11,;67.62,-20.56,;66.28,-19.79,;66.28,-18.25,;64.94,-17.49,;63.62,-18.26,;62.28,-17.48,;62.28,-15.94,;60.94,-15.17,;63.61,-15.17,;64.94,-15.94,;64.95,-20.56,;68.95,-19.78,;70.28,-20.55,;71.61,-19.78,;71.6,-18.24,;72.93,-17.46,;74.27,-18.22,;74.27,-19.76,;75.6,-20.53,;76.93,-19.76,;76.93,-18.21,;75.59,-17.44,;70.26,-17.47,;68.93,-18.25,)| Show InChI InChI=1S/C24H36N6O2/c1-2-3-10-25-24-27-16-21(23(29-24)28-19-5-7-20(31)8-6-19)22-9-4-18(15-26-22)17-30-11-13-32-14-12-30/h4,9,15-16,19-20,31H,2-3,5-8,10-14,17H2,1H3,(H2,25,27,28,29)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase phosphorylation in human 697 B-ALL cells after 1 hr by Western blot analysis				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444077 (CHEMBL3092788) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(CN2CCOCC2)ccn1 |r,wU:11.10,wD:14.14,(16.07,-32.76,;17.4,-31.99,;18.74,-32.76,;20.07,-31.99,;21.4,-32.76,;22.74,-31.99,;24.07,-32.77,;25.41,-31.99,;25.4,-30.44,;24.07,-29.68,;24.06,-28.14,;22.73,-27.37,;21.4,-28.15,;20.06,-27.37,;20.06,-25.83,;18.73,-25.06,;21.4,-25.06,;22.73,-25.83,;22.74,-30.45,;26.73,-29.67,;28.07,-30.44,;29.4,-29.67,;30.73,-30.43,;32.06,-29.66,;33.39,-30.43,;34.72,-29.66,;34.72,-28.12,;33.39,-27.35,;32.05,-28.12,;29.39,-28.12,;28.05,-27.36,;26.72,-28.14,)| Show InChI InChI=1S/C24H36N6O2/c1-2-3-9-26-24-27-16-21(23(29-24)28-19-4-6-20(31)7-5-19)22-15-18(8-10-25-22)17-30-11-13-32-14-12-30/h8,10,15-16,19-20,31H,2-7,9,11-14,17H2,1H3,(H2,26,27,28,29)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444046 (CHEMBL3092781) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(NCCc2ccccc2)ncc1-c1ccccn1 |r,wU:4.7,wD:1.0,(4.22,-46.58,;5.55,-47.35,;5.55,-48.89,;6.89,-49.66,;8.21,-48.89,;8.21,-47.35,;6.89,-46.58,;9.55,-49.66,;9.55,-51.2,;8.23,-51.97,;8.22,-53.51,;6.89,-54.28,;5.56,-53.51,;4.22,-54.28,;2.89,-53.51,;2.9,-51.97,;1.57,-51.2,;.23,-51.96,;.24,-53.51,;1.57,-54.28,;9.56,-54.28,;10.9,-53.51,;10.89,-51.96,;12.22,-51.19,;13.55,-51.96,;14.88,-51.18,;14.88,-49.64,;13.53,-48.88,;12.22,-49.65,)| Show InChI InChI=1S/C23H27N5O/c29-19-11-9-18(10-12-19)27-22-20(21-8-4-5-14-24-21)16-26-23(28-22)25-15-13-17-6-2-1-3-7-17/h1-8,14,16,18-19,29H,9-13,15H2,(H2,25,26,27,28)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444085 (CHEMBL3092785 | US9649309, Compound UNC1917A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.34,-10.98,;16.67,-10.21,;18,-10.98,;19.34,-10.21,;20.67,-10.98,;22,-10.22,;23.34,-10.99,;24.68,-10.21,;24.67,-8.66,;23.33,-7.9,;23.33,-6.36,;21.99,-5.59,;20.67,-6.37,;19.33,-5.59,;19.33,-4.05,;18,-3.28,;20.67,-3.28,;21.99,-4.05,;22.01,-8.67,;26,-7.89,;27.33,-8.66,;28.66,-7.89,;28.66,-6.34,;27.31,-5.58,;25.99,-6.36,)| Show InChI InChI=1S/C19H27N5O/c1-2-3-11-21-19-22-13-16(17-6-4-5-12-20-17)18(24-19)23-14-7-9-15(25)10-8-14/h4-6,12-15,25H,2-3,7-11H2,1H3,(H2,21,22,23,24)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444041 (CHEMBL3092787) Show SMILES CCCCNc1ncc(c(NC[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:12.11,wD:15.15,(.58,-12.75,;1.91,-11.98,;3.24,-12.75,;4.58,-11.98,;5.91,-12.75,;7.24,-11.98,;8.58,-12.75,;9.92,-11.98,;9.91,-10.43,;8.58,-9.67,;8.57,-8.13,;7.23,-7.36,;7.23,-5.82,;5.91,-5.06,;5.89,-3.53,;7.23,-2.76,;7.22,-1.22,;8.57,-3.52,;8.57,-5.05,;7.25,-10.44,;11.24,-9.66,;12.57,-10.43,;13.9,-9.65,;13.9,-8.11,;12.55,-7.35,;11.23,-8.12,)| Show InChI InChI=1S/C20H30N6/c1-2-3-11-23-20-25-14-17(18-6-4-5-12-22-18)19(26-20)24-13-15-7-9-16(21)10-8-15/h4-6,12,14-16H,2-3,7-11,13,21H2,1H3,(H2,23,24,25,26)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444064 (CHEMBL3092801 | US9649309, Compound UNC2999A) Show SMILES CCCCNc1ncc(c(Nc2ccc(N)cc2)n1)-c1ccccn1 Show InChI InChI=1S/C19H22N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-10,12-13H,2-3,11,20H2,1H3,(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444076 (CHEMBL3092789) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cccc(CN2CCOCC2)n1 |r,wU:11.10,wD:14.14,(35.47,-32.95,;36.81,-32.18,;38.14,-32.95,;39.47,-32.19,;40.81,-32.96,;42.14,-32.19,;43.48,-32.96,;44.81,-32.19,;44.81,-30.64,;43.47,-29.87,;43.47,-28.33,;42.13,-27.57,;40.81,-28.34,;39.47,-27.56,;39.47,-26.02,;38.14,-25.25,;40.8,-25.25,;42.13,-26.02,;42.14,-30.64,;46.14,-29.86,;47.47,-30.63,;48.8,-29.86,;48.79,-28.32,;47.45,-27.55,;47.44,-26.01,;48.77,-25.23,;50.1,-26,;51.43,-25.22,;51.42,-23.68,;50.08,-22.92,;48.75,-23.69,;46.12,-28.33,)| Show InChI InChI=1S/C24H36N6O2/c1-2-3-11-25-24-26-16-21(23(29-24)28-18-7-9-20(31)10-8-18)22-6-4-5-19(27-22)17-30-12-14-32-15-13-30/h4-6,16,18,20,31H,2-3,7-15,17H2,1H3,(H2,25,26,28,29)/t18-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444052 (CHEMBL3092775 | US9649309, Compound UNC3022A) Show SMILES CCCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:12.11,wD:15.15,(63.37,-31.5,;64.7,-32.28,;66.03,-31.51,;67.37,-32.28,;68.7,-31.51,;70.03,-32.28,;71.37,-31.51,;72.7,-32.28,;74.04,-31.51,;74.03,-29.96,;72.7,-29.2,;72.69,-27.66,;71.36,-26.89,;70.03,-27.66,;68.7,-26.89,;68.7,-25.35,;67.36,-24.57,;70.03,-24.58,;71.36,-25.34,;71.37,-29.97,;75.37,-29.18,;76.7,-29.96,;78.03,-29.18,;78.02,-27.64,;76.68,-26.88,;75.36,-27.65,)| Show InChI InChI=1S/C20H29N5O/c1-2-3-5-13-22-20-23-14-17(18-7-4-6-12-21-18)19(25-20)24-15-8-10-16(26)11-9-15/h4,6-7,12,14-16,26H,2-3,5,8-11,13H2,1H3,(H2,22,23,24,25)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444074 (CHEMBL3092791) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN(C)C)cn1 |r,wU:11.10,wD:14.14,(-4.06,-43.37,;-2.72,-42.6,;-1.39,-43.37,;-.05,-42.6,;1.29,-43.37,;2.62,-42.6,;3.96,-43.37,;5.29,-42.6,;5.29,-41.05,;3.95,-40.29,;3.95,-38.75,;2.61,-37.98,;1.29,-38.75,;-.06,-37.98,;-.06,-36.44,;-1.39,-35.67,;1.29,-35.67,;2.61,-36.44,;2.63,-41.06,;6.62,-40.28,;7.95,-41.05,;9.28,-40.27,;9.27,-38.73,;10.6,-37.96,;11.94,-38.72,;13.26,-37.94,;11.95,-40.26,;7.93,-37.97,;6.6,-38.75,)| Show InChI InChI=1S/C22H34N6O/c1-4-5-12-23-22-25-14-19(20-11-6-16(13-24-20)15-28(2)3)21(27-22)26-17-7-9-18(29)10-8-17/h6,11,13-14,17-18,29H,4-5,7-10,12,15H2,1-3H3,(H2,23,25,26,27)/t17-,18-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444068 (CHEMBL3092797) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNCCO)cn1 |r,wU:11.10,wD:14.14,(43.3,-58.78,;44.63,-58.01,;45.97,-58.78,;47.3,-58.01,;48.63,-58.78,;49.97,-58.01,;51.3,-58.78,;52.64,-58.01,;52.63,-56.46,;51.3,-55.7,;51.29,-54.16,;49.96,-53.39,;48.63,-54.16,;47.29,-53.39,;47.29,-51.84,;45.96,-51.07,;48.63,-51.08,;49.96,-51.84,;49.97,-56.47,;53.96,-55.68,;55.3,-56.46,;56.63,-55.68,;56.62,-54.14,;57.95,-53.36,;59.29,-54.13,;60.62,-53.35,;61.96,-54.11,;63.28,-53.34,;55.27,-53.38,;53.95,-54.15,)| Show InChI InChI=1S/C22H34N6O2/c1-2-3-10-24-22-26-15-19(20-9-4-16(14-25-20)13-23-11-12-29)21(28-22)27-17-5-7-18(30)8-6-17/h4,9,14-15,17-18,23,29-30H,2-3,5-8,10-13H2,1H3,(H2,24,26,27,28)/t17-,18-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444072 (CHEMBL3092793) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C(=O)NC1CCN(C)CC1 |r,wU:11.10,wD:14.14,(42.31,-47.3,;43.64,-46.53,;44.98,-47.3,;46.31,-46.53,;47.64,-47.3,;48.98,-46.53,;50.31,-47.3,;51.65,-46.53,;51.65,-44.98,;50.31,-44.22,;50.31,-42.68,;48.97,-41.91,;47.64,-42.68,;46.31,-41.91,;46.31,-40.36,;44.97,-39.59,;47.64,-39.6,;48.97,-40.36,;48.98,-44.99,;52.98,-44.2,;54.31,-44.98,;55.64,-44.2,;55.63,-42.66,;54.29,-41.9,;52.96,-42.67,;56.96,-41.88,;56.95,-40.34,;58.3,-42.65,;59.63,-41.87,;60.96,-42.64,;62.29,-41.87,;62.29,-40.33,;63.62,-39.56,;60.95,-39.56,;59.61,-40.34,)| Show InChI InChI=1S/C26H39N7O2/c1-3-4-13-27-26-29-17-22(24(32-26)30-19-6-8-21(34)9-7-19)23-10-5-18(16-28-23)25(35)31-20-11-14-33(2)15-12-20/h5,10,16-17,19-21,34H,3-4,6-9,11-15H2,1-2H3,(H,31,35)(H2,27,29,30,32)/t19-,21-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444070 (CHEMBL3092795) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNC2CCCCC2)cn1 |r,wU:11.10,wD:14.14,(-.85,-56.03,;.49,-55.27,;1.83,-56.04,;3.16,-55.27,;4.49,-56.04,;5.83,-55.27,;7.16,-56.04,;8.5,-55.27,;8.49,-53.72,;7.16,-52.95,;7.15,-51.42,;5.82,-50.65,;4.49,-51.42,;3.16,-50.65,;3.15,-49.1,;1.82,-48.33,;4.49,-48.34,;5.82,-49.1,;5.83,-53.73,;9.83,-52.94,;11.16,-53.71,;12.49,-52.94,;12.48,-51.4,;13.81,-50.62,;15.15,-51.39,;16.48,-50.61,;17.81,-51.38,;19.14,-50.61,;19.14,-49.07,;17.8,-48.3,;16.46,-49.08,;11.14,-50.63,;9.81,-51.41,)| Show InChI InChI=1S/C26H40N6O/c1-2-3-15-27-26-30-18-23(25(32-26)31-21-10-12-22(33)13-11-21)24-14-9-19(17-29-24)16-28-20-7-5-4-6-8-20/h9,14,17-18,20-22,28,33H,2-8,10-13,15-16H2,1H3,(H2,27,30,31,32)/t21-,22-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444073 (CHEMBL3092792) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)S(=O)(=O)N1CCOCC1 |r,wU:11.10,wD:14.14,(17.06,-43.23,;18.4,-42.47,;19.73,-43.24,;21.06,-42.47,;22.4,-43.24,;23.73,-42.47,;25.07,-43.24,;26.4,-42.47,;26.4,-40.92,;25.06,-40.15,;25.06,-38.61,;23.72,-37.85,;22.4,-38.62,;21.06,-37.85,;21.06,-36.3,;19.73,-35.53,;22.39,-35.54,;23.72,-36.3,;23.73,-40.93,;27.73,-40.14,;29.06,-40.91,;30.39,-40.14,;30.39,-38.6,;29.04,-37.83,;27.72,-38.61,;31.72,-37.82,;32.48,-36.48,;30.94,-36.49,;33.05,-38.59,;33.05,-40.13,;34.38,-40.89,;35.71,-40.12,;35.71,-38.58,;34.37,-37.81,)| Show InChI InChI=1S/C23H34N6O4S/c1-2-3-10-24-23-26-16-20(22(28-23)27-17-4-6-18(30)7-5-17)21-9-8-19(15-25-21)34(31,32)29-11-13-33-14-12-29/h8-9,15-18,30H,2-7,10-14H2,1H3,(H2,24,26,27,28)/t17-,18-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444069 (CHEMBL3092796) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNC2CC2)cn1 |r,wU:11.10,wD:14.14,(20.96,-58.36,;22.3,-57.6,;23.63,-58.37,;24.96,-57.6,;26.3,-58.37,;27.63,-57.6,;28.96,-58.37,;30.3,-57.6,;30.3,-56.05,;28.96,-55.28,;28.96,-53.74,;27.62,-52.98,;26.29,-53.75,;24.96,-52.98,;24.96,-51.43,;23.62,-50.66,;26.29,-50.67,;27.62,-51.43,;27.63,-56.06,;31.63,-55.27,;32.96,-56.04,;34.29,-55.27,;34.28,-53.73,;35.61,-52.95,;36.95,-53.72,;38.28,-52.94,;39.81,-52.93,;39.04,-51.6,;32.94,-52.96,;31.61,-53.74,)| Show InChI InChI=1S/C23H34N6O/c1-2-3-12-24-23-27-15-20(22(29-23)28-18-7-9-19(30)10-8-18)21-11-4-16(14-26-21)13-25-17-5-6-17/h4,11,14-15,17-19,25,30H,2-3,5-10,12-13H2,1H3,(H2,24,27,28,29)/t18-,19-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444063 (CHEMBL3092809 | US9649309, Compound UNC2961A) Show SMILES CCCCNc1ncc(c(NC2CCNCC2)n1)-c1ccccn1 Show InChI InChI=1S/C18H26N6/c1-2-3-9-21-18-22-13-15(16-6-4-5-10-20-16)17(24-18)23-14-7-11-19-12-8-14/h4-6,10,13-14,19H,2-3,7-9,11-12H2,1H3,(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444075 (CHEMBL3092790) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCC(F)(F)CC2)cn1 |r,wU:11.10,wD:14.14,(52.92,-33.3,;54.26,-32.53,;55.59,-33.3,;56.93,-32.54,;58.26,-33.31,;59.59,-32.54,;60.93,-33.31,;62.26,-32.54,;62.26,-30.99,;60.92,-30.22,;60.92,-28.68,;59.58,-27.92,;58.26,-28.69,;56.92,-27.91,;56.92,-26.37,;55.59,-25.6,;58.26,-25.6,;59.58,-26.37,;59.6,-30.99,;63.59,-30.21,;64.92,-30.98,;66.25,-30.21,;66.25,-28.67,;67.58,-27.89,;68.91,-28.65,;68.91,-30.19,;70.24,-30.96,;71.58,-30.19,;72.35,-31.52,;73.12,-30.18,;71.57,-28.64,;70.23,-27.87,;64.9,-27.9,;63.58,-28.68,)| Show InChI InChI=1S/C25H36F2N6O/c1-2-3-12-28-24-30-16-21(23(32-24)31-19-5-7-20(34)8-6-19)22-9-4-18(15-29-22)17-33-13-10-25(26,27)11-14-33/h4,9,15-16,19-20,34H,2-3,5-8,10-14,17H2,1H3,(H2,28,30,31,32)/t19-,20-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444070 (CHEMBL3092795) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNC2CCCCC2)cn1 |r,wU:11.10,wD:14.14,(-.85,-56.03,;.49,-55.27,;1.83,-56.04,;3.16,-55.27,;4.49,-56.04,;5.83,-55.27,;7.16,-56.04,;8.5,-55.27,;8.49,-53.72,;7.16,-52.95,;7.15,-51.42,;5.82,-50.65,;4.49,-51.42,;3.16,-50.65,;3.15,-49.1,;1.82,-48.33,;4.49,-48.34,;5.82,-49.1,;5.83,-53.73,;9.83,-52.94,;11.16,-53.71,;12.49,-52.94,;12.48,-51.4,;13.81,-50.62,;15.15,-51.39,;16.48,-50.61,;17.81,-51.38,;19.14,-50.61,;19.14,-49.07,;17.8,-48.3,;16.46,-49.08,;11.14,-50.63,;9.81,-51.41,)| Show InChI InChI=1S/C26H40N6O/c1-2-3-15-27-26-30-18-23(25(32-26)31-21-10-12-22(33)13-11-21)24-14-9-19(17-29-24)16-28-20-7-5-4-6-8-20/h9,14,17-18,20-22,28,33H,2-8,10-13,15-16H2,1H3,(H2,27,30,31,32)/t21-,22-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444051 (CHEMBL3092776 | US9649309, Compound UNC3054A) Show SMILES CCCC(C)Nc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:12.11,wD:15.15,(.76,-42.22,;2.1,-41.45,;3.43,-42.22,;4.76,-41.46,;4.76,-39.92,;6.1,-42.23,;7.43,-41.46,;8.76,-42.23,;10.1,-41.46,;10.1,-39.91,;8.76,-39.14,;8.76,-37.6,;7.42,-36.84,;6.09,-37.61,;4.76,-36.83,;4.76,-35.29,;3.42,-34.52,;6.09,-34.52,;7.42,-35.29,;7.43,-39.91,;11.43,-39.13,;12.76,-39.9,;14.09,-39.13,;14.08,-37.59,;12.74,-36.82,;11.42,-37.59,)| Show InChI InChI=1S/C20H29N5O/c1-3-6-14(2)23-20-22-13-17(18-7-4-5-12-21-18)19(25-20)24-15-8-10-16(26)11-9-15/h4-5,7,12-16,26H,3,6,8-11H2,1-2H3,(H2,22,23,24,25)/t14?,15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444043 (CHEMBL3092784) Show SMILES OCCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:12.11,wD:15.15,(50.03,-56.64,;51.36,-57.41,;52.7,-56.64,;54.03,-57.41,;55.36,-56.64,;56.7,-57.41,;58.03,-56.64,;59.37,-57.41,;60.7,-56.64,;60.7,-55.09,;59.36,-54.33,;59.36,-52.79,;58.02,-52.02,;56.7,-52.79,;55.36,-52.02,;55.36,-50.48,;54.03,-49.7,;56.69,-49.71,;58.02,-50.47,;58.03,-55.1,;62.03,-54.32,;63.36,-55.09,;64.69,-54.31,;64.69,-52.77,;63.34,-52.01,;62.03,-52.78,)| Show InChI InChI=1S/C19H27N5O2/c25-12-4-3-11-21-19-22-13-16(17-5-1-2-10-20-17)18(24-19)23-14-6-8-15(26)9-7-14/h1-2,5,10,13-15,25-26H,3-4,6-9,11-12H2,(H2,21,22,23,24)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444053 (CHEMBL3092774 | US9649309, Compound UNC3020A) Show SMILES CCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:10.9,wD:13.13,(52.63,-30.64,;53.96,-31.41,;55.29,-30.64,;56.63,-31.41,;57.96,-30.64,;59.29,-31.41,;60.63,-30.64,;60.63,-29.09,;59.29,-28.32,;59.29,-26.78,;57.95,-26.02,;56.62,-26.79,;55.29,-26.02,;55.29,-24.47,;53.95,-23.7,;56.62,-23.71,;57.95,-24.47,;57.96,-29.09,;61.96,-28.31,;63.29,-29.08,;64.62,-28.31,;64.61,-26.77,;63.27,-26,;61.95,-26.78,)| Show InChI InChI=1S/C18H25N5O/c1-2-10-20-18-21-12-15(16-5-3-4-11-19-16)17(23-18)22-13-6-8-14(24)9-7-13/h3-5,11-14,24H,2,6-10H2,1H3,(H2,20,21,22,23)/t13-,14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444065 (CHEMBL3092800) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](CN)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(31.68,-9.79,;33.01,-9.02,;34.35,-9.79,;35.68,-9.02,;37.01,-9.8,;38.35,-9.03,;39.68,-9.8,;41.02,-9.03,;41.01,-7.48,;39.68,-6.71,;39.67,-5.17,;38.34,-4.41,;37.01,-5.18,;35.67,-4.4,;35.67,-2.86,;34.34,-2.09,;34.34,-.55,;37.01,-2.09,;38.34,-2.86,;38.35,-7.48,;42.34,-6.7,;43.68,-7.47,;45,-6.7,;45,-5.16,;43.65,-4.39,;42.34,-5.16,)| Show InChI InChI=1S/C20H30N6/c1-2-3-11-23-20-24-14-17(18-6-4-5-12-22-18)19(26-20)25-16-9-7-15(13-21)8-10-16/h4-6,12,14-16H,2-3,7-11,13,21H2,1H3,(H2,23,24,25,26)/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444072 (CHEMBL3092793) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C(=O)NC1CCN(C)CC1 |r,wU:11.10,wD:14.14,(42.31,-47.3,;43.64,-46.53,;44.98,-47.3,;46.31,-46.53,;47.64,-47.3,;48.98,-46.53,;50.31,-47.3,;51.65,-46.53,;51.65,-44.98,;50.31,-44.22,;50.31,-42.68,;48.97,-41.91,;47.64,-42.68,;46.31,-41.91,;46.31,-40.36,;44.97,-39.59,;47.64,-39.6,;48.97,-40.36,;48.98,-44.99,;52.98,-44.2,;54.31,-44.98,;55.64,-44.2,;55.63,-42.66,;54.29,-41.9,;52.96,-42.67,;56.96,-41.88,;56.95,-40.34,;58.3,-42.65,;59.63,-41.87,;60.96,-42.64,;62.29,-41.87,;62.29,-40.33,;63.62,-39.56,;60.95,-39.56,;59.61,-40.34,)| Show InChI InChI=1S/C26H39N7O2/c1-3-4-13-27-26-29-17-22(24(32-26)30-19-6-8-21(34)9-7-19)23-10-5-18(16-28-23)25(35)31-20-11-14-33(2)15-12-20/h5,10,16-17,19-21,34H,3-4,6-9,11-15H2,1-2H3,(H,31,35)(H2,27,29,30,32)/t19-,21-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444074 (CHEMBL3092791) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN(C)C)cn1 |r,wU:11.10,wD:14.14,(-4.06,-43.37,;-2.72,-42.6,;-1.39,-43.37,;-.05,-42.6,;1.29,-43.37,;2.62,-42.6,;3.96,-43.37,;5.29,-42.6,;5.29,-41.05,;3.95,-40.29,;3.95,-38.75,;2.61,-37.98,;1.29,-38.75,;-.06,-37.98,;-.06,-36.44,;-1.39,-35.67,;1.29,-35.67,;2.61,-36.44,;2.63,-41.06,;6.62,-40.28,;7.95,-41.05,;9.28,-40.27,;9.27,-38.73,;10.6,-37.96,;11.94,-38.72,;13.26,-37.94,;11.95,-40.26,;7.93,-37.97,;6.6,-38.75,)| Show InChI InChI=1S/C22H34N6O/c1-4-5-12-23-22-25-14-19(20-11-6-16(13-24-20)15-28(2)3)21(27-22)26-17-7-9-18(29)10-8-17/h6,11,13-14,17-18,29H,4-5,7-10,12,15H2,1-3H3,(H2,23,25,26,27)/t17-,18-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444068 (CHEMBL3092797) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNCCO)cn1 |r,wU:11.10,wD:14.14,(43.3,-58.78,;44.63,-58.01,;45.97,-58.78,;47.3,-58.01,;48.63,-58.78,;49.97,-58.01,;51.3,-58.78,;52.64,-58.01,;52.63,-56.46,;51.3,-55.7,;51.29,-54.16,;49.96,-53.39,;48.63,-54.16,;47.29,-53.39,;47.29,-51.84,;45.96,-51.07,;48.63,-51.08,;49.96,-51.84,;49.97,-56.47,;53.96,-55.68,;55.3,-56.46,;56.63,-55.68,;56.62,-54.14,;57.95,-53.36,;59.29,-54.13,;60.62,-53.35,;61.96,-54.11,;63.28,-53.34,;55.27,-53.38,;53.95,-54.15,)| Show InChI InChI=1S/C22H34N6O2/c1-2-3-10-24-22-26-15-19(20-9-4-16(14-25-20)13-23-11-12-29)21(28-22)27-17-5-7-18(30)8-6-17/h4,9,14-15,17-18,23,29-30H,2-3,5-8,10-13H2,1H3,(H2,24,26,27,28)/t17-,18-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444073 (CHEMBL3092792) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)S(=O)(=O)N1CCOCC1 |r,wU:11.10,wD:14.14,(17.06,-43.23,;18.4,-42.47,;19.73,-43.24,;21.06,-42.47,;22.4,-43.24,;23.73,-42.47,;25.07,-43.24,;26.4,-42.47,;26.4,-40.92,;25.06,-40.15,;25.06,-38.61,;23.72,-37.85,;22.4,-38.62,;21.06,-37.85,;21.06,-36.3,;19.73,-35.53,;22.39,-35.54,;23.72,-36.3,;23.73,-40.93,;27.73,-40.14,;29.06,-40.91,;30.39,-40.14,;30.39,-38.6,;29.04,-37.83,;27.72,-38.61,;31.72,-37.82,;32.48,-36.48,;30.94,-36.49,;33.05,-38.59,;33.05,-40.13,;34.38,-40.89,;35.71,-40.12,;35.71,-38.58,;34.37,-37.81,)| Show InChI InChI=1S/C23H34N6O4S/c1-2-3-10-24-23-26-16-20(22(28-23)27-17-4-6-18(30)7-5-17)21-9-8-19(15-25-21)34(31,32)29-11-13-33-14-12-29/h8-9,15-18,30H,2-7,10-14H2,1H3,(H2,24,26,27,28)/t17-,18-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444062 (CHEMBL3092765 | US9649309, Compound UNC2962A) Show SMILES CCCCNc1ncc(c(NCC2CCNCC2)n1)-c1ccccn1 Show InChI InChI=1S/C19H28N6/c1-2-3-9-22-19-24-14-16(17-6-4-5-10-21-17)18(25-19)23-13-15-7-11-20-12-8-15/h4-6,10,14-15,20H,2-3,7-9,11-13H2,1H3,(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444046 (CHEMBL3092781) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(NCCc2ccccc2)ncc1-c1ccccn1 |r,wU:4.7,wD:1.0,(4.22,-46.58,;5.55,-47.35,;5.55,-48.89,;6.89,-49.66,;8.21,-48.89,;8.21,-47.35,;6.89,-46.58,;9.55,-49.66,;9.55,-51.2,;8.23,-51.97,;8.22,-53.51,;6.89,-54.28,;5.56,-53.51,;4.22,-54.28,;2.89,-53.51,;2.9,-51.97,;1.57,-51.2,;.23,-51.96,;.24,-53.51,;1.57,-54.28,;9.56,-54.28,;10.9,-53.51,;10.89,-51.96,;12.22,-51.19,;13.55,-51.96,;14.88,-51.18,;14.88,-49.64,;13.53,-48.88,;12.22,-49.65,)| Show InChI InChI=1S/C23H27N5O/c29-19-11-9-18(10-12-19)27-22-20(21-8-4-5-14-24-21)16-26-23(28-22)25-15-13-17-6-2-1-3-7-17/h1-8,14,16,18-19,29H,9-13,15H2,(H2,25,26,27,28)/t18-,19-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444048 (CHEMBL3092779 | US9649309, Compound UNC3053A) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(NC2CCCCC2)ncc1-c1ccccn1 |r,wU:4.7,wD:1.0,(42.68,-36.74,;44.01,-37.51,;44.01,-39.05,;45.35,-39.82,;46.67,-39.05,;46.67,-37.51,;45.35,-36.74,;48.01,-39.82,;48.01,-41.36,;46.69,-42.13,;46.68,-43.67,;45.35,-44.44,;44.02,-43.67,;44.02,-42.13,;42.7,-41.36,;41.36,-42.12,;41.36,-43.67,;42.69,-44.45,;48.02,-44.45,;49.35,-43.67,;49.35,-42.12,;50.68,-41.35,;52.01,-42.12,;53.34,-41.35,;53.34,-39.8,;51.99,-39.04,;50.68,-39.81,)| Show InChI InChI=1S/C21H29N5O/c27-17-11-9-16(10-12-17)24-20-18(19-8-4-5-13-22-19)14-23-21(26-20)25-15-6-2-1-3-7-15/h4-5,8,13-17,27H,1-3,6-7,9-12H2,(H2,23,24,25,26)/t16-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444069 (CHEMBL3092796) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CNC2CC2)cn1 |r,wU:11.10,wD:14.14,(20.96,-58.36,;22.3,-57.6,;23.63,-58.37,;24.96,-57.6,;26.3,-58.37,;27.63,-57.6,;28.96,-58.37,;30.3,-57.6,;30.3,-56.05,;28.96,-55.28,;28.96,-53.74,;27.62,-52.98,;26.29,-53.75,;24.96,-52.98,;24.96,-51.43,;23.62,-50.66,;26.29,-50.67,;27.62,-51.43,;27.63,-56.06,;31.63,-55.27,;32.96,-56.04,;34.29,-55.27,;34.28,-53.73,;35.61,-52.95,;36.95,-53.72,;38.28,-52.94,;39.81,-52.93,;39.04,-51.6,;32.94,-52.96,;31.61,-53.74,)| Show InChI InChI=1S/C23H34N6O/c1-2-3-12-24-23-27-15-20(22(29-23)28-18-7-9-19(30)10-8-18)21-11-4-16(14-26-21)13-25-17-5-6-17/h4,11,14-15,17-19,25,30H,2-3,5-10,12-13H2,1H3,(H2,24,27,28,29)/t18-,19-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444066 (CHEMBL3092799) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.98,-7.45,;17.32,-6.68,;18.65,-7.45,;19.98,-6.68,;21.32,-7.45,;22.65,-6.69,;23.98,-7.46,;25.32,-6.68,;25.32,-5.13,;23.98,-4.37,;23.98,-2.83,;22.64,-2.06,;21.31,-2.84,;19.98,-2.06,;19.98,-.52,;18.64,.26,;21.31,.25,;22.64,-.52,;22.65,-5.14,;26.65,-4.36,;27.98,-5.13,;29.31,-4.36,;29.3,-2.81,;27.96,-2.05,;26.64,-2.82,)| Show InChI InChI=1S/C19H28N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-6,12-15H,2-3,7-11,20H2,1H3,(H2,22,23,24,25)/t14-,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444080 (CHEMBL3092805) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)N1CCN(C)CC1 |r,wU:11.10,wD:14.14,(13.34,-23.32,;14.67,-22.55,;16,-23.32,;17.34,-22.56,;18.67,-23.33,;20.01,-22.56,;21.34,-23.33,;22.68,-22.56,;22.67,-21.01,;21.34,-20.24,;21.33,-18.7,;20,-17.94,;18.67,-18.71,;17.33,-17.93,;17.33,-16.39,;16,-15.62,;18.67,-15.62,;20,-16.39,;20.01,-21.01,;24,-20.23,;25.33,-21,;26.66,-20.23,;26.66,-18.69,;25.31,-17.92,;23.99,-18.7,;27.99,-17.91,;29.31,-18.68,;30.64,-17.91,;30.64,-16.37,;31.97,-15.6,;29.3,-15.6,;27.97,-16.37,)| Show InChI InChI=1S/C24H37N7O/c1-3-4-11-25-24-27-17-21(23(29-24)28-18-5-8-20(32)9-6-18)22-10-7-19(16-26-22)31-14-12-30(2)13-15-31/h7,10,16-18,20,32H,3-6,8-9,11-15H2,1-2H3,(H2,25,27,28,29)/t18-,20-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444071 (CHEMBL3092794) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(NC(=O)C2CCN(C)CC2)cn1 |r,wU:11.10,wD:14.14,(41.44,-46.25,;42.77,-45.48,;44.11,-46.25,;45.44,-45.48,;46.77,-46.25,;48.11,-45.48,;49.44,-46.25,;50.78,-45.48,;50.78,-43.93,;49.44,-43.17,;49.44,-41.63,;48.1,-40.86,;46.77,-41.63,;45.44,-40.86,;45.44,-39.32,;44.1,-38.54,;46.77,-38.55,;48.1,-39.31,;48.11,-43.94,;52.11,-43.16,;53.44,-43.93,;54.77,-43.15,;54.76,-41.61,;56.09,-40.83,;57.43,-41.6,;57.44,-43.14,;58.76,-40.82,;60.09,-41.59,;61.42,-40.82,;61.42,-39.28,;62.75,-38.51,;60.08,-38.51,;58.74,-39.29,;53.42,-40.85,;52.09,-41.62,)| Show InChI InChI=1S/C26H39N7O2/c1-3-4-13-27-26-29-17-22(24(32-26)30-19-5-8-21(34)9-6-19)23-10-7-20(16-28-23)31-25(35)18-11-14-33(2)15-12-18/h7,10,16-19,21,34H,3-6,8-9,11-15H2,1-2H3,(H,31,35)(H2,27,29,30,32)/t19-,21-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444042 (CHEMBL3092807) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCOCC2)cn1 |r,wU:11.10,wD:14.14,(58.28,-22.87,;59.62,-22.1,;60.95,-22.87,;62.28,-22.11,;63.62,-22.88,;64.95,-22.11,;66.29,-22.88,;67.62,-22.11,;67.62,-20.56,;66.28,-19.79,;66.28,-18.25,;64.94,-17.49,;63.62,-18.26,;62.28,-17.48,;62.28,-15.94,;60.94,-15.17,;63.61,-15.17,;64.94,-15.94,;64.95,-20.56,;68.95,-19.78,;70.28,-20.55,;71.61,-19.78,;71.6,-18.24,;72.93,-17.46,;74.27,-18.22,;74.27,-19.76,;75.6,-20.53,;76.93,-19.76,;76.93,-18.21,;75.59,-17.44,;70.26,-17.47,;68.93,-18.25,)| Show InChI InChI=1S/C24H36N6O2/c1-2-3-10-25-24-27-16-21(23(29-24)28-19-5-7-20(31)8-6-19)22-9-4-18(15-26-22)17-30-11-13-32-14-12-30/h4,9,15-16,19-20,31H,2-3,5-8,10-14,17H2,1H3,(H2,25,27,28,29)/t19-,20-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444079 (CHEMBL3092806) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCN(C)CC2)cn1 |r,wU:11.10,wD:14.14,(37.6,-21.62,;38.94,-20.85,;40.27,-21.62,;41.6,-20.85,;42.94,-21.62,;44.27,-20.86,;45.61,-21.63,;46.94,-20.85,;46.94,-19.3,;45.6,-18.54,;45.6,-17,;44.26,-16.23,;42.94,-17.01,;41.6,-16.23,;41.6,-14.69,;40.26,-13.92,;42.93,-13.92,;44.26,-14.69,;44.27,-19.31,;48.27,-18.53,;49.6,-19.3,;50.93,-18.53,;50.92,-16.98,;52.25,-16.21,;53.59,-16.97,;53.59,-18.51,;54.92,-19.27,;56.25,-18.5,;57.59,-19.27,;56.25,-16.96,;54.91,-16.19,;49.58,-16.22,;48.25,-17,)| Show InChI InChI=1S/C25H39N7O/c1-3-4-11-26-25-28-17-22(24(30-25)29-20-6-8-21(33)9-7-20)23-10-5-19(16-27-23)18-32-14-12-31(2)13-15-32/h5,10,16-17,20-21,33H,3-4,6-9,11-15,18H2,1-2H3,(H2,26,28,29,30)/t20-,21-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444047 (CHEMBL3092780) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(NCc2ccccc2)ncc1-c1ccccn1 |r,wU:4.7,wD:1.0,(57.34,-36.38,;58.68,-37.15,;58.68,-38.69,;60.01,-39.47,;61.34,-38.7,;61.34,-37.15,;60.01,-36.38,;62.68,-39.46,;62.68,-41,;61.35,-41.77,;61.35,-43.32,;60.02,-44.09,;58.68,-43.31,;57.35,-44.08,;56.02,-43.31,;54.68,-44.08,;54.68,-45.62,;56.02,-46.39,;57.35,-45.62,;62.68,-44.09,;64.02,-43.32,;64.02,-41.76,;65.35,-40.99,;66.68,-41.76,;68.01,-40.99,;68,-39.45,;66.66,-38.68,;65.34,-39.45,)| Show InChI InChI=1S/C22H25N5O/c28-18-11-9-17(10-12-18)26-21-19(20-8-4-5-13-23-20)15-25-22(27-21)24-14-16-6-2-1-3-7-16/h1-8,13,15,17-18,28H,9-12,14H2,(H2,24,25,26,27)/t17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444075 (CHEMBL3092790) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCC(F)(F)CC2)cn1 |r,wU:11.10,wD:14.14,(52.92,-33.3,;54.26,-32.53,;55.59,-33.3,;56.93,-32.54,;58.26,-33.31,;59.59,-32.54,;60.93,-33.31,;62.26,-32.54,;62.26,-30.99,;60.92,-30.22,;60.92,-28.68,;59.58,-27.92,;58.26,-28.69,;56.92,-27.91,;56.92,-26.37,;55.59,-25.6,;58.26,-25.6,;59.58,-26.37,;59.6,-30.99,;63.59,-30.21,;64.92,-30.98,;66.25,-30.21,;66.25,-28.67,;67.58,-27.89,;68.91,-28.65,;68.91,-30.19,;70.24,-30.96,;71.58,-30.19,;72.35,-31.52,;73.12,-30.18,;71.57,-28.64,;70.23,-27.87,;64.9,-27.9,;63.58,-28.68,)| Show InChI InChI=1S/C25H36F2N6O/c1-2-3-12-28-24-30-16-21(23(32-24)31-19-5-7-20(34)8-6-19)22-9-4-18(15-29-22)17-33-13-10-25(26,27)11-14-33/h4,9,15-16,19-20,34H,2-3,5-8,10-14,17H2,1H3,(H2,28,30,31,32)/t19-,20-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair

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