Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for entry = 50043648   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50444153 (CHEMBL3093304) Show SMILES OC(=O)c1cc(ccc1N1CCC(Cc2ccc(F)cc2)C1)C(F)(F)F Show InChI InChI=1S/C19H17F4NO2/c20-15-4-1-12(2-5-15)9-13-7-8-24(11-13)17-6-3-14(19(21,22)23)10-16(17)18(25)26/h1-6,10,13H,7-9,11H2,(H,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444147 (CHEMBL3093396) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCOCc1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C21H22F3NO4/c22-21(23,24)16-6-7-19(18(12-16)20(26)27)25-9-8-17(13-25)29-11-10-28-14-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,26,27)/t17-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444138 (CHEMBL3093392) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444140 (CHEMBL3093394) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ncccc1F)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-14-2-1-6-23-15(14)10-27-12-5-7-24(9-12)16-4-3-11(18(20,21)22)8-13(16)17(25)26/h1-4,6,8,12H,5,7,9-10H2,(H,25,26)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444141 (CHEMBL3093393) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cn1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-12-2-3-13(23-8-12)10-27-14-5-6-24(9-14)16-4-1-11(18(20,21)22)7-15(16)17(25)26/h1-4,7-8,14H,5-6,9-10H2,(H,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444150 (CHEMBL3093307) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H17F4NO3/c20-14-4-1-12(2-5-14)11-27-15-7-8-24(10-15)17-6-3-13(19(21,22)23)9-16(17)18(25)26/h1-6,9,15H,7-8,10-11H2,(H,25,26)/t15-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444148 (CHEMBL3093309) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCC1CC1)C(F)(F)F |r| Show InChI InChI=1S/C17H20F3NO3/c18-17(19,20)12-3-4-15(14(9-12)16(22)23)21-7-5-13(10-21)24-8-6-11-1-2-11/h3-4,9,11,13H,1-2,5-8,10H2,(H,22,23)/t13-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444144 (CHEMBL3093302) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444158 (CHEMBL3093401) Show SMILES Fc1ccc(O[C@H]2CCN(C2)c2ccc(cc2-c2nnn[nH]2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C18H15F4N5O/c19-12-2-4-13(5-3-12)28-14-7-8-27(10-14)16-6-1-11(18(20,21)22)9-15(16)17-23-25-26-24-17/h1-6,9,14H,7-8,10H2,(H,23,24,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444139 (CHEMBL3093395) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1cncc(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-13-5-11(7-23-8-13)10-27-14-3-4-24(9-14)16-2-1-12(18(20,21)22)6-15(16)17(25)26/h1-2,5-8,14H,3-4,9-10H2,(H,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444141 (CHEMBL3093393) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cn1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-12-2-3-13(23-8-12)10-27-14-5-6-24(9-14)16-4-1-11(18(20,21)22)7-15(16)17(25)26/h1-4,7-8,14H,5-6,9-10H2,(H,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	219	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444149 (CHEMBL3093308) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCC1CC1)C(F)(F)F |r| Show InChI InChI=1S/C16H18F3NO3/c17-16(18,19)11-3-4-14(13(7-11)15(21)22)20-6-5-12(8-20)23-9-10-1-2-10/h3-4,7,10,12H,1-2,5-6,8-9H2,(H,21,22)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444151 (CHEMBL3093306) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(Cl)nc1)C(F)(F)F |r| Show InChI InChI=1S/C17H14ClF3N2O3/c18-15-4-2-11(8-22-15)26-12-5-6-23(9-12)14-3-1-10(17(19,20)21)7-13(14)16(24)25/h1-4,7-8,12H,5-6,9H2,(H,24,25)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444138 (CHEMBL3093392) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444138 (CHEMBL3093392) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of full length human endothelial lipase transfected in HEK293 cells using PED-A1 as substrate preincubated for 30 mins followed by substra...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444140 (CHEMBL3093394) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ncccc1F)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-14-2-1-6-23-15(14)10-27-12-5-7-24(9-12)16-4-3-11(18(20,21)22)8-13(16)17(25)26/h1-4,6,8,12H,5,7,9-10H2,(H,25,26)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444154 (CHEMBL3093303) Show SMILES OC(=O)c1cc(ccc1N1CC[C@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444139 (CHEMBL3093395) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1cncc(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-13-5-11(7-23-8-13)10-27-14-3-4-24(9-14)16-2-1-12(18(20,21)22)6-15(16)17(25)26/h1-2,5-8,14H,3-4,9-10H2,(H,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444143 (CHEMBL3093391) Show SMILES CCCCO[C@H]1CCN(C1)c1ccc(cc1C(O)=O)C(F)(F)F |r| Show InChI InChI=1S/C16H20F3NO3/c1-2-3-8-23-12-6-7-20(10-12)14-5-4-11(16(17,18)19)9-13(14)15(21)22/h4-5,9,12H,2-3,6-8,10H2,1H3,(H,21,22)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444152 (CHEMBL3093305) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(cn1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C18H14F6N2O3/c19-17(20,21)10-1-3-14(13(7-10)16(27)28)26-6-5-12(9-26)29-15-4-2-11(8-25-15)18(22,23)24/h1-4,7-8,12H,5-6,9H2,(H,27,28)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	372	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444146 (CHEMBL3093398) Show SMILES CCOCCO[C@H]1CCN(C1)c1ccc(cc1C(O)=O)C(F)(F)F |r| Show InChI InChI=1S/C16H20F3NO4/c1-2-23-7-8-24-12-5-6-20(10-12)14-4-3-11(16(17,18)19)9-13(14)15(21)22/h3-4,9,12H,2,5-8,10H2,1H3,(H,21,22)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	499	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444142 (CHEMBL3093399) Show SMILES COCCOCCO[C@H]1CCN(C1)c1ccc(cc1C(O)=O)C(F)(F)F |r| Show InChI InChI=1S/C17H22F3NO5/c1-24-6-7-25-8-9-26-13-4-5-21(11-13)15-3-2-12(17(18,19)20)10-14(15)16(22)23/h2-3,10,13H,4-9,11H2,1H3,(H,22,23)/t13-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	551	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444160 (CHEMBL3093397) Show SMILES OCCO[C@H]1CCN(C1)c1ccc(cc1C(O)=O)C(F)(F)F |r| Show InChI InChI=1S/C14H16F3NO4/c15-14(16,17)9-1-2-12(11(7-9)13(20)21)18-4-3-10(8-18)22-6-5-19/h1-2,7,10,19H,3-6,8H2,(H,20,21)/t10-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444159 (CHEMBL3093400) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCN1CCOCC1)C(F)(F)F |r| Show InChI InChI=1S/C18H23F3N2O4/c19-18(20,21)13-1-2-16(15(11-13)17(24)25)23-4-3-14(12-23)27-10-7-22-5-8-26-9-6-22/h1-2,11,14H,3-10,12H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	659	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444145 (CHEMBL3093405) Show SMILES OC(=O)c1cc(ccc1NCC1CC1)C(F)(F)F Show InChI InChI=1S/C12H12F3NO2/c13-12(14,15)8-3-4-10(9(5-8)11(17)18)16-6-7-1-2-7/h3-5,7,16H,1-2,6H2,(H,17,18)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444155 (CHEMBL3093404) Show SMILES CC(O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H19F4NO2/c1-12(25)17-10-13(19(21,22)23)2-7-18(17)24-9-8-16(11-24)26-15-5-3-14(20)4-6-15/h2-7,10,12,16,25H,8-9,11H2,1H3/t12?,16-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444161 (CHEMBL3093301) Show SMILES OC(=O)c1cc(ccc1N1CC(C1)Oc1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H13F4NO3/c18-11-2-4-12(5-3-11)25-13-8-22(9-13)15-6-1-10(17(19,20)21)7-14(15)16(23)24/h1-7,13H,8-9H2,(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444153 (CHEMBL3093304) Show SMILES OC(=O)c1cc(ccc1N1CCC(Cc2ccc(F)cc2)C1)C(F)(F)F Show InChI InChI=1S/C19H17F4NO2/c20-15-4-1-12(2-5-15)9-13-7-8-24(11-13)17-6-3-14(19(21,22)23)10-16(17)18(25)26/h1-6,10,13H,7-9,11H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444145 (CHEMBL3093405) Show SMILES OC(=O)c1cc(ccc1NCC1CC1)C(F)(F)F Show InChI InChI=1S/C12H12F3NO2/c13-12(14,15)8-3-4-10(9(5-8)11(17)18)16-6-7-1-2-7/h3-5,7,16H,1-2,6H2,(H,17,18)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444144 (CHEMBL3093302) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444138 (CHEMBL3093392) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444157 (CHEMBL3093402) Show SMILES NS(=O)(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C17H16F4N2O3S/c18-12-2-4-13(5-3-12)26-14-7-8-23(10-14)15-6-1-11(17(19,20)21)9-16(15)27(22,24)25/h1-6,9,14H,7-8,10H2,(H2,22,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444156 (CHEMBL3093403) Show SMILES CC(=O)NS(=O)(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H18F4N2O4S/c1-12(26)24-30(27,28)18-10-13(19(21,22)23)2-7-17(18)25-9-8-16(11-25)29-15-5-3-14(20)4-6-15/h2-7,10,16H,8-9,11H2,1H3,(H,24,26)/t16-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444145 (CHEMBL3093405) Show SMILES OC(=O)c1cc(ccc1NCC1CC1)C(F)(F)F Show InChI InChI=1S/C12H12F3NO2/c13-12(14,15)8-3-4-10(9(5-8)11(17)18)16-6-7-1-2-7/h3-5,7,16H,1-2,6H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444162 (CHEMBL3093300) Show SMILES OC(=O)c1cc(ccc1N1CCC(CC1)Oc1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C19H17F4NO3/c20-13-2-4-14(5-3-13)27-15-7-9-24(10-8-15)17-6-1-12(19(21,22)23)11-16(17)18(25)26/h1-6,11,15H,7-10H2,(H,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444141 (CHEMBL3093393) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cn1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-12-2-3-13(23-8-12)10-27-14-5-6-24(9-14)16-4-1-11(18(20,21)22)7-15(16)17(25)26/h1-4,7-8,14H,5-6,9-10H2,(H,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444140 (CHEMBL3093394) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ncccc1F)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-14-2-1-6-23-15(14)10-27-12-5-7-24(9-12)16-4-3-11(18(20,21)22)8-13(16)17(25)26/h1-4,6,8,12H,5,7,9-10H2,(H,25,26)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444152 (CHEMBL3093305) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(cn1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C18H14F6N2O3/c19-17(20,21)10-1-3-14(13(7-10)16(27)28)26-6-5-12(9-26)29-15-4-2-11(8-25-15)18(22,23)24/h1-4,7-8,12H,5-6,9H2,(H,27,28)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444138 (CHEMBL3093392) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444139 (CHEMBL3093395) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1cncc(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-13-5-11(7-23-8-13)10-27-14-3-4-24(9-14)16-2-1-12(18(20,21)22)6-15(16)17(25)26/h1-2,5-8,14H,3-4,9-10H2,(H,25,26)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444143 (CHEMBL3093391) Show SMILES CCCCO[C@H]1CCN(C1)c1ccc(cc1C(O)=O)C(F)(F)F |r| Show InChI InChI=1S/C16H20F3NO3/c1-2-3-8-23-12-6-7-20(10-12)14-5-4-11(16(17,18)19)9-13(14)15(21)22/h4-5,9,12H,2-3,6-8,10H2,1H3,(H,21,22)/t12-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444151 (CHEMBL3093306) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(Cl)nc1)C(F)(F)F |r| Show InChI InChI=1S/C17H14ClF3N2O3/c18-15-4-2-11(8-22-15)26-12-5-6-23(9-12)14-3-1-10(17(19,20)21)7-13(14)16(24)25/h1-4,7-8,12H,5-6,9H2,(H,24,25)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444150 (CHEMBL3093307) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H17F4NO3/c20-14-4-1-12(2-5-14)11-27-15-7-8-24(10-15)17-6-3-13(19(21,22)23)9-16(17)18(25)26/h1-6,9,15H,7-8,10-11H2,(H,25,26)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444147 (CHEMBL3093396) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCOCc1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C21H22F3NO4/c22-21(23,24)16-6-7-19(18(12-16)20(26)27)25-9-8-17(13-25)29-11-10-28-14-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,26,27)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444154 (CHEMBL3093303) Show SMILES OC(=O)c1cc(ccc1N1CC[C@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444148 (CHEMBL3093309) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCC1CC1)C(F)(F)F |r| Show InChI InChI=1S/C17H20F3NO3/c18-17(19,20)12-3-4-15(14(9-12)16(22)23)21-7-5-13(10-21)24-8-6-11-1-2-11/h3-4,9,11,13H,1-2,5-8,10H2,(H,22,23)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444139 (CHEMBL3093395) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1cncc(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-13-5-11(7-23-8-13)10-27-14-3-4-24(9-14)16-2-1-12(18(20,21)22)6-15(16)17(25)26/h1-2,5-8,14H,3-4,9-10H2,(H,25,26)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444149 (CHEMBL3093308) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCC1CC1)C(F)(F)F |r| Show InChI InChI=1S/C16H18F3NO3/c17-16(18,19)11-3-4-14(13(7-11)15(21)22)20-6-5-12(8-20)23-9-10-1-2-10/h3-4,7,10,12H,1-2,5-6,8-9H2,(H,21,22)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444141 (CHEMBL3093393) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cn1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-12-2-3-13(23-8-12)10-27-14-5-6-24(9-14)16-4-1-11(18(20,21)22)7-15(16)17(25)26/h1-4,7-8,14H,5-6,9-10H2,(H,25,26)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444140 (CHEMBL3093394) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ncccc1F)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-14-2-1-6-23-15(14)10-27-12-5-7-24(9-12)16-4-3-11(18(20,21)22)8-13(16)17(25)26/h1-4,6,8,12H,5,7,9-10H2,(H,25,26)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 55 total )  |  Next  |  Last  >>

Jump to: