Compile Data Set for Download or QSAR

Found 88 hits Enz. Inhib. hit(s) with all data for entry = 50043770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446088 (CHEMBL3108870) Show SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl Show InChI InChI=1S/C16H12ClFN4O3S2/c17-13-7-10(1-6-14(13)18)8-15(23)20-11-2-4-12(5-3-11)27(24,25)22-16-21-19-9-26-16/h1-7,9H,8H2,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Competitive inhibition Trypanosoma brucei PFK using fructose-6-phosphate as substrate by Line-weaver Burk plot analysis				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446088 (CHEMBL3108870) Show SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl Show InChI InChI=1S/C16H12ClFN4O3S2/c17-13-7-10(1-6-14(13)18)8-15(23)20-11-2-4-12(5-3-11)27(24,25)22-16-21-19-9-26-16/h1-7,9H,8H2,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Mixed type inhibition Trypanosoma brucei PFK using ATP as substrate by Line-weaver Burk plot analysis				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446088 (CHEMBL3108870) Show SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl Show InChI InChI=1S/C16H12ClFN4O3S2/c17-13-7-10(1-6-14(13)18)8-15(23)20-11-2-4-12(5-3-11)27(24,25)22-16-21-19-9-26-16/h1-7,9H,8H2,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446090 (CHEMBL3108868) Show SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)cc1Cl Show InChI InChI=1S/C17H13ClFN3O3S2/c18-14-9-11(1-6-15(14)19)10-16(23)21-12-2-4-13(5-3-12)27(24,25)22-17-20-7-8-26-17/h1-9H,10H2,(H,20,22)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446091 (CHEMBL3108867) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)cc1Cl Show InChI InChI=1S/C17H13Cl2N3O3S2/c18-14-6-1-11(9-15(14)19)10-16(23)21-12-2-4-13(5-3-12)27(24,25)22-17-20-7-8-26-17/h1-9H,10H2,(H,20,22)(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446089 (CHEMBL3108869) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O3S2/c17-13-6-1-10(7-14(13)18)8-15(23)20-11-2-4-12(5-3-11)27(24,25)22-16-21-19-9-26-16/h1-7,9H,8H2,(H,20,23)(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446091 (CHEMBL3108867) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)cc1Cl Show InChI InChI=1S/C17H13Cl2N3O3S2/c18-14-6-1-11(9-15(14)19)10-16(23)21-12-2-4-13(5-3-12)27(24,25)22-17-20-7-8-26-17/h1-9H,10H2,(H,20,22)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446089 (CHEMBL3108869) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O3S2/c17-13-6-1-10(7-14(13)18)8-15(23)20-11-2-4-12(5-3-11)27(24,25)22-16-21-19-9-26-16/h1-7,9H,8H2,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446090 (CHEMBL3108868) Show SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)cc1Cl Show InChI InChI=1S/C17H13ClFN3O3S2/c18-14-9-11(1-6-15(14)19)10-16(23)21-12-2-4-13(5-3-12)27(24,25)22-17-20-7-8-26-17/h1-9H,10H2,(H,20,22)(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446100 (CHEMBL3108858) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccon2)cc1Cl Show InChI InChI=1S/C17H13Cl2N3O4S/c18-14-6-1-11(9-15(14)19)10-17(23)20-12-2-4-13(5-3-12)27(24,25)22-16-7-8-26-21-16/h1-9H,10H2,(H,20,23)(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446095 (CHEMBL3108863) Show SMILES OC(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)cc1 Show InChI InChI=1S/C21H16Cl2N2O5S/c22-18-10-1-13(11-19(18)23)12-20(26)24-15-6-8-17(9-7-15)31(29,30)25-16-4-2-14(3-5-16)21(27)28/h1-11,25H,12H2,(H,24,26)(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446088 (CHEMBL3108870) Show SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl Show InChI InChI=1S/C16H12ClFN4O3S2/c17-13-7-10(1-6-14(13)18)8-15(23)20-11-2-4-12(5-3-11)27(24,25)22-16-21-19-9-26-16/h1-7,9H,8H2,(H,20,23)(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446129 (CHEMBL1394402) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C18H15Cl2N3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)21-18(24)10-12-2-7-15(19)16(20)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446097 (CHEMBL3108861) Show SMILES OC(=O)c1cccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)c1 Show InChI InChI=1S/C21H16Cl2N2O5S/c22-18-9-4-13(10-19(18)23)11-20(26)24-15-5-7-17(8-6-15)31(29,30)25-16-3-1-2-14(12-16)21(27)28/h1-10,12,25H,11H2,(H,24,26)(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446095 (CHEMBL3108863) Show SMILES OC(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)cc1 Show InChI InChI=1S/C21H16Cl2N2O5S/c22-18-10-1-13(11-19(18)23)12-20(26)24-15-6-8-17(9-7-15)31(29,30)25-16-4-2-14(3-5-16)21(27)28/h1-11,25H,12H2,(H,24,26)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446100 (CHEMBL3108858) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccon2)cc1Cl Show InChI InChI=1S/C17H13Cl2N3O4S/c18-14-6-1-11(9-15(14)19)10-17(23)20-12-2-4-13(5-3-12)27(24,25)22-16-7-8-26-21-16/h1-9H,10H2,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446129 (CHEMBL1394402) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C18H15Cl2N3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)21-18(24)10-12-2-7-15(19)16(20)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446102 (CHEMBL3108856) Show SMILES OS(=O)(=O)c1ccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C14H11Cl2NO4S/c15-12-6-1-9(7-13(12)16)8-14(18)17-10-2-4-11(5-3-10)22(19,20)21/h1-7H,8H2,(H,17,18)(H,19,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446111 (CHEMBL3108848) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(F)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C18H15ClFN3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)21-18(24)10-12-2-7-16(20)15(19)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446099 (CHEMBL3108859) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccn[nH]2)cc1Cl Show InChI InChI=1S/C17H14Cl2N4O3S/c18-14-6-1-11(9-15(14)19)10-17(24)21-12-2-4-13(5-3-12)27(25,26)23-16-7-8-20-22-16/h1-9H,10H2,(H,21,24)(H2,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446097 (CHEMBL3108861) Show SMILES OC(=O)c1cccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)c1 Show InChI InChI=1S/C21H16Cl2N2O5S/c22-18-9-4-13(10-19(18)23)11-20(26)24-15-5-7-17(8-6-15)31(29,30)25-16-3-1-2-14(12-16)21(27)28/h1-10,12,25H,11H2,(H,24,26)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446112 (CHEMBL3108847) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(F)c3)cc2)no1 Show InChI InChI=1S/C18H15ClFN3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)21-18(24)10-12-2-7-15(19)16(20)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446102 (CHEMBL3108856) Show SMILES OS(=O)(=O)c1ccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C14H11Cl2NO4S/c15-12-6-1-9(7-13(12)16)8-14(18)17-10-2-4-11(5-3-10)22(19,20)21/h1-7H,8H2,(H,17,18)(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446113 (CHEMBL3108846) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cc2)no1 Show InChI InChI=1S/C19H15ClF3N3O4S/c1-11-8-17(25-30-11)26-31(28,29)14-5-3-13(4-6-14)24-18(27)10-12-2-7-16(20)15(9-12)19(21,22)23/h2-9H,10H2,1H3,(H,24,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446112 (CHEMBL3108847) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(F)c3)cc2)no1 Show InChI InChI=1S/C18H15ClFN3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)21-18(24)10-12-2-7-15(19)16(20)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446099 (CHEMBL3108859) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccn[nH]2)cc1Cl Show InChI InChI=1S/C17H14Cl2N4O3S/c18-14-6-1-11(9-15(14)19)10-17(24)21-12-2-4-13(5-3-12)27(25,26)23-16-7-8-20-22-16/h1-9H,10H2,(H,21,24)(H2,20,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446094 (CHEMBL3108864) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2cncnc2)cc1Cl Show InChI InChI=1S/C18H14Cl2N4O3S/c19-16-6-1-12(7-17(16)20)8-18(25)23-13-2-4-15(5-3-13)28(26,27)24-14-9-21-11-22-10-14/h1-7,9-11,24H,8H2,(H,23,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446111 (CHEMBL3108848) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(F)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C18H15ClFN3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)21-18(24)10-12-2-7-16(20)15(19)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446094 (CHEMBL3108864) Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2cncnc2)cc1Cl Show InChI InChI=1S/C18H14Cl2N4O3S/c19-16-6-1-12(7-17(16)20)8-18(25)23-13-2-4-15(5-3-13)28(26,27)24-14-9-21-11-22-10-14/h1-7,9-11,24H,8H2,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446113 (CHEMBL3108846) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cc2)no1 Show InChI InChI=1S/C19H15ClF3N3O4S/c1-11-8-17(25-30-11)26-31(28,29)14-5-3-13(4-6-14)24-18(27)10-12-2-7-16(20)15(9-12)19(21,22)23/h2-9H,10H2,1H3,(H,24,27)(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446098 (CHEMBL3108860) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)n(C)n1 Show InChI InChI=1S/C19H18Cl2N4O3S/c1-12-9-18(25(2)23-12)24-29(27,28)15-6-4-14(5-7-15)22-19(26)11-13-3-8-16(20)17(21)10-13/h3-10,24H,11H2,1-2H3,(H,22,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446124 (CHEMBL3108835) Show SMILES CN(C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccc(cc1)S(=O)(=O)Nc1cc(C)on1 Show InChI InChI=1S/C19H17Cl2N3O4S/c1-12-9-18(22-28-12)23-29(26,27)15-6-4-14(5-7-15)24(2)19(25)11-13-3-8-16(20)17(21)10-13/h3-10H,11H2,1-2H3,(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446115 (CHEMBL3108844) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)cc3)cc2)no1 Show InChI InChI=1S/C18H16ClN3O4S/c1-12-10-17(21-26-12)22-27(24,25)16-8-6-15(7-9-16)20-18(23)11-13-2-4-14(19)5-3-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446093 (CHEMBL3108865) Show SMILES Oc1cccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)c1 Show InChI InChI=1S/C20H16Cl2N2O4S/c21-18-9-4-13(10-19(18)22)11-20(26)23-14-5-7-17(8-6-14)29(27,28)24-15-2-1-3-16(25)12-15/h1-10,12,24-25H,11H2,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446093 (CHEMBL3108865) Show SMILES Oc1cccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)c1 Show InChI InChI=1S/C20H16Cl2N2O4S/c21-18-9-4-13(10-19(18)22)11-20(26)23-14-5-7-17(8-6-14)29(27,28)24-15-2-1-3-16(25)12-15/h1-10,12,24-25H,11H2,(H,23,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446106 (CHEMBL3108852) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc4ccccc4c3)cc2)no1 Show InChI InChI=1S/C22H19N3O4S/c1-15-12-21(24-29-15)25-30(27,28)20-10-8-19(9-11-20)23-22(26)14-16-6-7-17-4-2-3-5-18(17)13-16/h2-13H,14H2,1H3,(H,23,26)(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446115 (CHEMBL3108844) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)cc3)cc2)no1 Show InChI InChI=1S/C18H16ClN3O4S/c1-12-10-17(21-26-12)22-27(24,25)16-8-6-15(7-9-16)20-18(23)11-13-2-4-14(19)5-3-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446120 (CHEMBL3108839) Show SMILES CN(c1cc(C)on1)S(=O)(=O)c1ccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C19H17Cl2N3O4S/c1-12-9-18(23-28-12)24(2)29(26,27)15-6-4-14(5-7-15)22-19(25)11-13-3-8-16(20)17(21)10-13/h3-10H,11H2,1-2H3,(H,22,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446098 (CHEMBL3108860) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)n(C)n1 Show InChI InChI=1S/C19H18Cl2N4O3S/c1-12-9-18(25(2)23-12)24-29(27,28)15-6-4-14(5-7-15)22-19(26)11-13-3-8-16(20)17(21)10-13/h3-10,24H,11H2,1-2H3,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446118 (CHEMBL3108841) Show SMILES Cc1cc(NS(=O)(=O)Cc2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C19H17Cl2N3O4S/c1-12-8-18(23-28-12)24-29(26,27)11-13-2-5-15(6-3-13)22-19(25)10-14-4-7-16(20)17(21)9-14/h2-9H,10-11H2,1H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446116 (CHEMBL3108843) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3cccc(Cl)c3)cc2)no1 Show InChI InChI=1S/C18H16ClN3O4S/c1-12-9-17(21-26-12)22-27(24,25)16-7-5-15(6-8-16)20-18(23)11-13-3-2-4-14(19)10-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446122 (CHEMBL3108837) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(cc2)C(=O)NCc2ccc(Cl)c(Cl)c2)no1 Show InChI InChI=1S/C18H15Cl2N3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)18(24)21-10-12-2-7-15(19)16(20)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446120 (CHEMBL3108839) Show SMILES CN(c1cc(C)on1)S(=O)(=O)c1ccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C19H17Cl2N3O4S/c1-12-9-18(23-28-12)24(2)29(26,27)15-6-4-14(5-7-15)22-19(25)11-13-3-8-16(20)17(21)10-13/h3-10H,11H2,1-2H3,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) Show SMILES Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O Show InChI InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446118 (CHEMBL3108841) Show SMILES Cc1cc(NS(=O)(=O)Cc2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C19H17Cl2N3O4S/c1-12-8-18(23-28-12)24-29(26,27)11-13-2-5-15(6-3-13)22-19(25)10-14-4-7-16(20)17(21)9-14/h2-9H,10-11H2,1H3,(H,22,25)(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma cruzi)	BDBM50446110 (CHEMBL3108849) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(C)c(F)c3)cc2)no1 Show InChI InChI=1S/C19H18FN3O4S/c1-12-3-4-14(10-17(12)20)11-19(24)21-15-5-7-16(8-6-15)28(25,26)23-18-9-13(2)27-22-18/h3-10H,11H2,1-2H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446114 (CHEMBL3108845) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)cc3Cl)cc2)no1 Show InChI InChI=1S/C18H15Cl2N3O4S/c1-11-8-17(22-27-11)23-28(25,26)15-6-4-14(5-7-15)21-18(24)9-12-2-3-13(19)10-16(12)20/h2-8,10H,9H2,1H3,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446122 (CHEMBL3108837) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(cc2)C(=O)NCc2ccc(Cl)c(Cl)c2)no1 Show InChI InChI=1S/C18H15Cl2N3O4S/c1-11-8-17(22-27-11)23-28(25,26)14-5-3-13(4-6-14)18(24)21-10-12-2-7-15(19)16(20)9-12/h2-9H,10H2,1H3,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446104 (CHEMBL3108854) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)CCc3ccc(Cl)c(Cl)c3)cc2)no1 Show InChI InChI=1S/C19H17Cl2N3O4S/c1-12-10-18(23-28-12)24-29(26,27)15-6-4-14(5-7-15)22-19(25)9-3-13-2-8-16(20)17(21)11-13/h2,4-8,10-11H,3,9H2,1H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei)	BDBM50446092 (CHEMBL3108866) Show SMILES CN(C)c1cccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)c1 Show InChI InChI=1S/C22H21Cl2N3O3S/c1-27(2)18-5-3-4-17(14-18)26-31(29,30)19-9-7-16(8-10-19)25-22(28)13-15-6-11-20(23)21(24)12-15/h3-12,14,26H,13H2,1-2H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair

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