Compile Data Set for Download or QSAR

Found 2922 hits Enz. Inhib. hit(s) with all data for entry = 496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273647 (US10071079, Example 432 | US10478424, Example 432) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(CCO)CCO)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C28H37N5O2/c1-18(2)26-24-15-21(20-6-10-32(11-7-20)23(8-12-34)9-13-35)4-5-25(24)31-27(26)22-14-19(3)28-29-17-30-33(28)16-22/h4-5,14-18,20,23,31,34-35H,6-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273316 (US10071079, Example 90 | US10478424, Example 90) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N2CCCC2)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C29H36N6O/c1-19(2)27-24-15-22(21-8-12-33(13-9-21)17-26(36)34-10-4-5-11-34)6-7-25(24)32-28(27)23-14-20(3)29-30-18-31-35(29)16-23/h6-7,14-16,18-19,21,32H,4-5,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274079 (US10071079, Example 865 | US10478424, Example 865) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC(F)(F)C2)CC1 Show InChI InChI=1S/C28H32F2N6O2/c1-17(2)25-21-10-19(18-6-8-34(9-7-18)13-24(37)35-14-28(29,30)15-35)4-5-22(21)33-26(25)20-11-23(38-3)27-31-16-32-36(27)12-20/h4-5,10-12,16-18,33H,6-9,13-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273536 (US10071079, Example 319 | US10478424, Example 319) Show SMILES CNC(=O)CN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C2CC2)c2ncnn2c1 Show InChI InChI=1S/C28H34N6O/c1-17(2)26-23-12-20(18-8-10-33(11-9-18)15-25(35)29-3)6-7-24(23)32-27(26)21-13-22(19-4-5-19)28-30-16-31-34(28)14-21/h6-7,12-14,16-19,32H,4-5,8-11,15H2,1-3H3,(H,29,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273856 (US10071079, Example 642 | US10478424, Example 642) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(C)C)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C27H31F3N6O/c1-16(2)24-20-11-18(17-7-9-35(10-8-17)23(37)14-34(3)4)5-6-22(20)33-25(24)19-12-21(27(28,29)30)26-31-15-32-36(26)13-19/h5-6,11-13,15-17,33H,7-10,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273910 (US10071079, Example 696 | US10478424, Example 696) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(C)C)-c1cc(C2CC2)c2ncnn2c1 Show InChI InChI=1S/C29H36N6O/c1-18(2)27-24-13-21(19-9-11-34(12-10-19)26(36)16-33(3)4)7-8-25(24)32-28(27)22-14-23(20-5-6-20)29-30-17-31-35(29)15-22/h7-8,13-15,17-20,32H,5-6,9-12,16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273911 (US10071079, Example 697 | US10478424, Example 697) Show SMILES CNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C2CC2)c2ncnn2c1 Show InChI InChI=1S/C28H34N6O/c1-17(2)26-23-12-20(18-8-10-33(11-9-18)25(35)14-29-3)6-7-24(23)32-27(26)21-13-22(19-4-5-19)28-30-16-31-34(28)15-21/h6-7,12-13,15-19,29,32H,4-5,8-11,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273981 (US10071079, Example 767 | US10478424, Example 767) Show SMILES CC(C)N(C)CC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C30H40N6O/c1-18(2)28-24-14-23(22-10-12-35(13-11-22)27(37)16-34(7)19(3)4)8-9-26(24)33-29(28)25-15-36-30(31-17-32-36)21(6)20(25)5/h8-9,14-15,17-19,22,33H,10-13,16H2,1-7H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273463 (US10071079, Example 246 | US10478424, Example 246) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(C)(C)O)CC1)-c1cc(C)c2nc(C)nn2c1 Show InChI InChI=1S/C28H37N5O/c1-17(2)25-23-14-21(20-9-11-32(12-10-20)16-28(5,6)34)7-8-24(23)30-26(25)22-13-18(3)27-29-19(4)31-33(27)15-22/h7-8,13-15,17,20,30,34H,9-12,16H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273470 (US10071079, Example 253 | US10071079, Example 263 ...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CCS(C)(=O)=O)CC1 Show InChI InChI=1S/C26H33N5O3S/c1-17(2)24-21-13-19(18-7-9-30(10-8-18)11-12-35(4,32)33)5-6-22(21)29-25(24)20-14-23(34-3)26-27-16-28-31(26)15-20/h5-6,13-18,29H,7-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273340 (US10071079, Example 119 | US10478424, Example 119) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cn2ncnc2c(Cl)c1C Show InChI InChI=1S/C23H26ClN5/c1-13(2)20-17-10-16(15-6-8-25-9-7-15)4-5-19(17)28-22(20)18-11-29-23(26-12-27-29)21(24)14(18)3/h4-5,10-13,15,25,28H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273606 (US10071079, Example 391 | US10478424, Example 391) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCCO)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C26H33N5O/c1-17(2)24-22-14-20(19-7-10-30(11-8-19)9-4-12-32)5-6-23(22)29-25(24)21-13-18(3)26-27-16-28-31(26)15-21/h5-6,13-17,19,29,32H,4,7-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273320 (8-ethyl-6-(3-isopropyl-5-(piperidin-4-yl)-1H-indol...) Show SMILES CCc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCNCC1 Show InChI InChI=1S/C24H29N5/c1-4-16-11-19(13-29-24(16)26-14-27-29)23-22(15(2)3)20-12-18(5-6-21(20)28-23)17-7-9-25-10-8-17/h5-6,11-15,17,25,28H,4,7-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273608 (US10071079, Example 393 | US10071079, Example 540 ...) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C1CCOC1)-c1cc(C)c2ncnn2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273855 (US10071079, Example 641 | US10478424, Example 641) Show SMILES CNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C26H29F3N6O/c1-15(2)23-19-10-17(16-6-8-34(9-7-16)22(36)12-30-3)4-5-21(19)33-24(23)18-11-20(26(27,28)29)25-31-14-32-35(25)13-18/h4-5,10-11,13-16,30,33H,6-9,12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273230 (6-(3-isopropyl-5-(piperidin-4-yl)-1H-indol-2-yl)-7...) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C24H29N5/c1-14(2)22-19-11-18(17-7-9-25-10-8-17)5-6-21(19)28-23(22)20-12-29-24(26-13-27-29)16(4)15(20)3/h5-6,11-14,17,25,28H,7-10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273234 (US10071079, Example 8) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(C[N+]#[C-])CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H28N6/c1-16(2)23-21-12-19(18-7-9-30(10-8-18)15-26-4)5-6-22(21)29-24(23)20-11-17(3)25-27-14-28-31(25)13-20/h5-6,11-14,16,18,29H,7-10,15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273237 (US10071079, Example 11 | US10478424, Example 11) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(N)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H30N6O/c1-15(2)23-20-11-18(17-6-8-30(9-7-17)13-22(26)32)4-5-21(20)29-24(23)19-10-16(3)25-27-14-28-31(25)12-19/h4-5,10-12,14-15,17,29H,6-9,13H2,1-3H3,(H2,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273251 (2-(4-(3-isopropyl-2-(8-methoxy-[1,2,4]triazolo[1,5...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N(C)C)CC1 Show InChI InChI=1S/C27H34N6O2/c1-17(2)25-21-12-19(18-8-10-32(11-9-18)15-24(34)31(3)4)6-7-22(21)30-26(25)20-13-23(35-5)27-28-16-29-33(27)14-20/h6-7,12-14,16-18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273255 (US10071079, Example 29 | US10478424, Example 29) Show SMILES CC(C)CN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C27H35N5/c1-17(2)14-31-10-8-20(9-11-31)21-6-7-24-23(13-21)25(18(3)4)26(30-24)22-12-19(5)27-28-16-29-32(27)15-22/h6-7,12-13,15-18,20,30H,8-11,14H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273271 (US10071079, Example 45 | US10478424, Example 45) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C1CCOCC1 Show InChI InChI=1S/C28H35N5O2/c1-18(2)26-23-14-20(19-6-10-32(11-7-19)22-8-12-35-13-9-22)4-5-24(23)31-27(26)21-15-25(34-3)28-29-17-30-33(28)16-21/h4-5,14-19,22,31H,6-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273769 (US10071079, Example 555 | US10478424, Example 555) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC2(C)COC2)CC1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C28H32F3N5O/c1-17(2)24-21-10-19(18-6-8-35(9-7-18)13-27(3)14-37-15-27)4-5-23(21)34-25(24)20-11-22(28(29,30)31)26-32-16-33-36(26)12-20/h4-5,10-12,16-18,34H,6-9,13-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274076 (US10071079, Example 862 | US10478424, Example 862) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)NCC2(C)COC2)CC1 Show InChI InChI=1S/C30H38N6O3/c1-19(2)27-23-11-21(20-7-9-35(10-8-20)14-26(37)31-15-30(3)16-39-17-30)5-6-24(23)34-28(27)22-12-25(38-4)29-32-18-33-36(29)13-22/h5-6,11-13,18-20,34H,7-10,14-17H2,1-4H3,(H,31,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273780 (US10071079, Example 566 | US10478424, Example 566) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC2(C)COC2)CC1 Show InChI InChI=1S/C28H35N5O2/c1-18(2)25-22-11-20(19-7-9-32(10-8-19)14-28(3)15-35-16-28)5-6-23(22)31-26(25)21-12-24(34-4)27-29-17-30-33(27)13-21/h5-6,11-13,17-19,31H,7-10,14-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273356 (US10071079, Example 138 | US10478424, Example 138) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cn2nc(C)nc2c(Cl)c1C Show InChI InChI=1S/C24H28ClN5/c1-13(2)21-18-11-17(16-7-9-26-10-8-16)5-6-20(18)28-23(21)19-12-30-24(22(25)14(19)3)27-15(4)29-30/h5-6,11-13,16,26,28H,7-10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273992 (US10071079, Example 778 | US10478424, Example 778) Show SMILES CCN(C)CC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI InChI=1S/C28H33F3N6O/c1-5-35(4)15-24(38)36-10-8-18(9-11-36)19-6-7-23-21(12-19)25(17(2)3)26(34-23)20-13-22(28(29,30)31)27-32-16-33-37(27)14-20/h6-7,12-14,16-18,34H,5,8-11,15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273368 (US10071079, Example 151 | US10478424, Example 151) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cc(C2CC2)c2ncnn2c1 Show InChI InChI=1S/C25H29N5/c1-15(2)23-21-11-18(16-7-9-26-10-8-16)5-6-22(21)29-24(23)19-12-20(17-3-4-17)25-27-14-28-30(25)13-19/h5-6,11-17,26,29H,3-4,7-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273537 (US10071079, Example 320 | US10478424, Example 320) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(C2CC2)c2ncnn2c1 Show InChI InChI=1S/C29H36N6O/c1-18(2)27-24-13-21(19-9-11-34(12-10-19)16-26(36)33(3)4)7-8-25(24)32-28(27)22-14-23(20-5-6-20)29-30-17-31-35(29)15-22/h7-8,13-15,17-20,32H,5-6,9-12,16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273321 (8-isopropyl-6-(3-isopropyl-5-(piperidin-4-yl)-1H-i...) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cc(C(C)C)c2ncnn2c1 Show InChI InChI=1S/C25H31N5/c1-15(2)20-12-19(13-30-25(20)27-14-28-30)24-23(16(3)4)21-11-18(5-6-22(21)29-24)17-7-9-26-10-8-17/h5-6,11-17,26,29H,7-10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273608 (US10071079, Example 393 | US10071079, Example 540 ...) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C1CCOC1)-c1cc(C)c2ncnn2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273249 (US10071079, Example 23 | US10478424, Example 23) Show SMILES CNC(=O)CN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(OC)c2ncnn2c1 Show InChI InChI=1S/C26H32N6O2/c1-16(2)24-20-11-18(17-7-9-31(10-8-17)14-23(33)27-3)5-6-21(20)30-25(24)19-12-22(34-4)26-28-15-29-32(26)13-19/h5-6,11-13,15-17,30H,7-10,14H2,1-4H3,(H,27,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273250 (US10071079, Example 24 | US10478424, Example 24) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(C)(C)O)CC1 Show InChI InChI=1S/C27H35N5O2/c1-17(2)24-21-12-19(18-8-10-31(11-9-18)15-27(3,4)33)6-7-22(21)30-25(24)20-13-23(34-5)26-28-16-29-32(26)14-20/h6-7,12-14,16-18,30,33H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273886 (US10071079, Example 672 | US10071079, Example 676 ...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C(=O)C1CCN(C)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273298 (US10071079, Example 72 | US10478424, Example 72) Show SMILES CCCNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C28H36N6O/c1-5-10-29-15-25(35)33-11-8-20(9-12-33)21-6-7-24-23(14-21)26(18(2)3)27(32-24)22-13-19(4)28-30-17-31-34(28)16-22/h6-7,13-14,16-18,20,29,32H,5,8-12,15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273770 (US10071079, Example 556 | US10071079, Example 557 ...) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C1CCOC1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274077 (US10071079, Example 863 | US10478424, Example 863) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC[C@@H](O)C2)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274078 (US10071079, Example 864 | US10478424, Example 864) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC(F)C2)CC1 Show InChI InChI=1S/C28H33FN6O2/c1-17(2)26-22-10-19(18-6-8-33(9-7-18)15-25(36)34-13-21(29)14-34)4-5-23(22)32-27(26)20-11-24(37-3)28-30-16-31-35(28)12-20/h4-5,10-12,16-18,21,32H,6-9,13-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274089 (US10071079, Example 875 | US10478424, Example 875) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC[C@H](F)C2)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273770 (US10071079, Example 556 | US10071079, Example 557 ...) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C1CCOC1)-c1cc(c2ncnn2c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273776 (US10071079, Example 562 | US10071079, Example 563 ...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C1CCOC(C)(C)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273779 (US10071079, Example 565 | US10478424, Example 565) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(C[C@@H]2COCCN2)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273781 (US10071079, Example 567) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C1CC(C1)[N+]#[C-] |(10.48,.67,;8.94,.67,;8.17,-.67,;6.63,-.67,;5.86,-2,;6.63,-3.33,;8.17,-3.33,;9.2,-4.48,;10.61,-3.85,;10.45,-2.32,;8.94,-2,;4.32,-2,;3.41,-3.25,;1.95,-2.77,;.62,-3.54,;-.72,-2.77,;-.72,-1.23,;.62,-.46,;1.95,-1.23,;3.41,-.75,;3.81,.73,;2.72,1.82,;5.3,1.13,;-2.05,-.46,;-3.39,-1.23,;-4.72,-.46,;-4.72,1.08,;-3.39,1.85,;-2.05,1.08,;-6.05,1.85,;-6.45,3.34,;-7.96,2.95,;-7.54,1.45,;-9.29,3.72,;-10.63,4.49,)| Show InChI InChI=1S/C28H32N6O/c1-17(2)26-23-11-19(18-7-9-33(10-8-18)22-13-21(14-22)29-3)5-6-24(23)32-27(26)20-12-25(35-4)28-30-16-31-34(28)15-20/h5-6,11-12,15-18,21-22,32H,7-10,13-14H2,1-2,4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273782 (US10071079, Example 568 | US10071079, Example 569 ...) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C1CCOC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273784 (US10071079, Example 570 | US10478424, Example 570) Show SMILES CNCCN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(OC)c2ncnn2c1 Show InChI InChI=1S/C26H34N6O/c1-17(2)24-21-13-19(18-7-10-31(11-8-18)12-9-27-3)5-6-22(21)30-25(24)20-14-23(33-4)26-28-16-29-32(26)15-20/h5-6,13-18,27,30H,7-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274149 (US10071079, Example 935 | US10478424, Example 935) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)OC1CCNCC1)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C30H38N6O2/c1-18(2)27-24-15-22(21-9-13-35(14-10-21)30(37)38-23-7-11-31-12-8-23)5-6-26(24)34-28(27)25-16-36-29(32-17-33-36)20(4)19(25)3/h5-6,15-18,21,23,31,34H,7-14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273841 (US10071079, Example 627 | US10478424, Example 627) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)[C@@H]1C[C@@H](F)CN1)-c1cc(C)c2ncnn2c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274155 (US10071079, Example 941 | US10478424, Example 941) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)OCC1CNC1)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H36N6O2/c1-17(2)26-23-11-22(21-7-9-34(10-8-21)29(36)37-15-20-12-30-13-20)5-6-25(23)33-27(26)24-14-35-28(31-16-32-35)19(4)18(24)3/h5-6,11,14,16-17,20-21,30,33H,7-10,12-13,15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair

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