Compile Data Set for Download or QSAR

Found 54 hits Enz. Inhib. hit(s) with all data for entry = 3140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28586 (1-{3-[(3-chlorophenyl)methoxy]-2-methylphenyl}pipe...) Show SMILES Cc1c(OCc2cccc(Cl)c2)cccc1N1CCNCC1 Show InChI InChI=1S/C18H21ClN2O/c1-14-17(21-10-8-20-9-11-21)6-3-7-18(14)22-13-15-4-2-5-16(19)12-15/h2-7,12,20H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.600	-52.1	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28583 (5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...) Show SMILES COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1 Show InChI InChI=1S/C20H22ClN3O3S2/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24/h3-6,11-12,22-23H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.660	-51.9	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28584 (1-[3-(benzyloxy)-2-methylphenyl]piperazine | tolyl...) Show SMILES Cc1c(OCc2ccccc2)cccc1N1CCNCC1 Show InChI InChI=1S/C18H22N2O/c1-15-17(20-12-10-19-11-13-20)8-5-9-18(15)21-14-16-6-3-2-4-7-16/h2-9,19H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30	-50.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28635 (2-methyl-3-(piperidin-4-yl)phenyl naphthalene-1-su...) Show SMILES Cc1c(OS(=O)(=O)c2cccc3ccccc23)cccc1C1CCNCC1 Show InChI InChI=1S/C22H23NO3S/c1-16-19(18-12-14-23-15-13-18)9-5-10-21(16)26-27(24,25)22-11-4-7-17-6-2-3-8-20(17)22/h2-11,18,23H,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.5	-50.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28620 (2-[1-(3-chlorophenyl)-2,2,2-trifluoroethoxy]-3-met...) Show SMILES Cc1c(OC(c2cccc(Cl)c2)C(F)(F)F)nccc1C1CCNCC1 Show InChI InChI=1S/C19H20ClF3N2O/c1-12-16(13-5-8-24-9-6-13)7-10-25-18(12)26-17(19(21,22)23)14-3-2-4-15(20)11-14/h2-4,7,10-11,13,17,24H,5-6,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.40	-49.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28594 (4-{3-[(3-fluorophenyl)methoxy]-2-methylphenyl}pipe...) Show SMILES Cc1c(OCc2cccc(F)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C19H22FNO/c1-14-18(16-8-10-21-11-9-16)6-3-7-19(14)22-13-15-4-2-5-17(20)12-15/h2-7,12,16,21H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.5	-48.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28636 (2-methyl-3-(piperidin-4-yl)phenyl naphthalene-2-su...) Show SMILES Cc1c(OS(=O)(=O)c2ccc3ccccc3c2)cccc1C1CCNCC1 Show InChI InChI=1S/C22H23NO3S/c1-16-21(18-11-13-23-14-12-18)7-4-8-22(16)26-27(24,25)20-10-9-17-5-2-3-6-19(17)15-20/h2-10,15,18,23H,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.70	-48.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28603 (4-{3-[(1S)-1-(3-chlorophenyl)ethoxy]-2-methylpheny...) Show SMILES C[C@H](Oc1cccc(C2CCNCC2)c1C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H24ClNO/c1-14-19(16-9-11-22-12-10-16)7-4-8-20(14)23-15(2)17-5-3-6-18(21)13-17/h3-8,13,15-16,22H,9-12H2,1-2H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.80	-48.3	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28595 (4-{3-[(3-chlorophenyl)methoxy]-2-methylphenyl}pipe...) Show SMILES Cc1c(OCc2cccc(Cl)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C19H22ClNO/c1-14-18(16-8-10-21-11-9-16)6-3-7-19(14)22-13-15-4-2-5-17(20)12-15/h2-7,12,16,21H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.30	-47.9	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28623 (4-[3-(3-chlorophenoxymethyl)-2-methylphenyl]piperi...) Show SMILES Cc1c(COc2cccc(Cl)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C19H22ClNO/c1-14-16(13-22-18-6-3-5-17(20)12-18)4-2-7-19(14)15-8-10-21-11-9-15/h2-7,12,15,21H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.5	-48.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28621 (3-methyl-4-(piperidin-4-yl)-2-[2,2,2-trifluoro-1-(...) Show SMILES Cc1c(OC(c2cccc(F)c2)C(F)(F)F)nccc1C1CCNCC1 Show InChI InChI=1S/C19H20F4N2O/c1-12-16(13-5-8-24-9-6-13)7-10-25-18(12)26-17(19(21,22)23)14-3-2-4-15(20)11-14/h2-4,7,10-11,13,17,24H,5-6,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.30	-47.8	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28628 (2-methyl-3-(piperidin-4-yl)phenyl 2-chlorobenzene-...) Show SMILES Cc1c(OS(=O)(=O)c2ccccc2Cl)cccc1C1CCNCC1 Show InChI InChI=1S/C18H20ClNO3S/c1-13-15(14-9-11-20-12-10-14)5-4-7-17(13)23-24(21,22)18-8-3-2-6-16(18)19/h2-8,14,20H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.80	-47.0	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28619 (2-[1-(3-chlorophenyl)propoxy]-3-methyl-4-(piperidi...) Show SMILES CCC(Oc1nccc(C2CCNCC2)c1C)c1cccc(Cl)c1 Show InChI InChI=1S/C20H25ClN2O/c1-3-19(16-5-4-6-17(21)13-16)24-20-14(2)18(9-12-23-20)15-7-10-22-11-8-15/h4-6,9,12-13,15,19,22H,3,7-8,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.40	-46.8	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28624 (4-[3-(3-fluorophenoxymethyl)-2-methylphenyl]piperi...) Show SMILES Cc1c(COc2cccc(F)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C19H22FNO/c1-14-16(13-22-18-6-3-5-17(20)12-18)4-2-7-19(14)15-8-10-21-11-9-15/h2-7,12,15,21H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.5	-46.7	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28601 (4-{3-[(1S)-1-(3-fluorophenyl)ethoxy]-2-methylpheny...) Show SMILES C[C@H](Oc1cccc(C2CCNCC2)c1C)c1cccc(F)c1 |r| Show InChI InChI=1S/C20H24FNO/c1-14-19(16-9-11-22-12-10-16)7-4-8-20(14)23-15(2)17-5-3-6-18(21)13-17/h3-8,13,15-16,22H,9-12H2,1-2H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.90	-46.1	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28607 (2-[(3-chlorophenyl)methoxy]-3-methyl-4-(piperidin-...) Show SMILES Cc1c(OCc2cccc(Cl)c2)nccc1C1CCNCC1 Show InChI InChI=1S/C18H21ClN2O/c1-13-17(15-5-8-20-9-6-15)7-10-21-18(13)22-12-14-3-2-4-16(19)11-14/h2-4,7,10-11,15,20H,5-6,8-9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.10	-46.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28589 (1-{3-[(3,4-difluorophenyl)methoxy]-2-methylphenyl}...) Show SMILES Cc1c(OCc2ccc(F)c(F)c2)cccc1N1CCNCC1 Show InChI InChI=1S/C18H20F2N2O/c1-13-17(22-9-7-21-8-10-22)3-2-4-18(13)23-12-14-5-6-15(19)16(20)11-14/h2-6,11,21H,7-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.30	-45.4	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28631 (2-methyl-3-(piperidin-4-yl)phenyl 2-methylbenzene-...) Show SMILES Cc1ccccc1S(=O)(=O)Oc1cccc(C2CCNCC2)c1C Show InChI InChI=1S/C19H23NO3S/c1-14-6-3-4-9-19(14)24(21,22)23-18-8-5-7-17(15(18)2)16-10-12-20-13-11-16/h3-9,16,20H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10.1	-45.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28585 (1-{3-[(3-fluorophenyl)methoxy]-2-methylphenyl}pipe...) Show SMILES Cc1c(OCc2cccc(F)c2)cccc1N1CCNCC1 Show InChI InChI=1S/C18H21FN2O/c1-14-17(21-10-8-20-9-11-21)6-3-7-18(14)22-13-15-4-2-5-16(19)12-15/h2-7,12,20H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10.3	-45.1	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28617 (2-[(1S)-1-(3-chlorophenyl)ethoxy]-3-methyl-4-(pipe...) Show SMILES C[C@H](Oc1nccc(C2CCNCC2)c1C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H23ClN2O/c1-13-18(15-6-9-21-10-7-15)8-11-22-19(13)23-14(2)16-4-3-5-17(20)12-16/h3-5,8,11-12,14-15,21H,6-7,9-10H2,1-2H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10.5	-45.5	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28634 (2-methyl-3-(piperidin-4-yl)phenyl 4-ethylbenzene-1...) Show SMILES CCc1ccc(cc1)S(=O)(=O)Oc1cccc(C2CCNCC2)c1C Show InChI InChI=1S/C20H25NO3S/c1-3-16-7-9-18(10-8-16)25(22,23)24-20-6-4-5-19(15(20)2)17-11-13-21-14-12-17/h4-10,17,21H,3,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11.3	-45.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28588 (1-{3-[(2-fluorophenyl)methoxy]-2-methylphenyl}pipe...) Show SMILES Cc1c(OCc2ccccc2F)cccc1N1CCNCC1 Show InChI InChI=1S/C18H21FN2O/c1-14-17(21-11-9-20-10-12-21)7-4-8-18(14)22-13-15-5-2-3-6-16(15)19/h2-8,20H,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11.6	-44.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28630 (2-methyl-3-(piperidin-4-yl)phenyl 2-fluorobenzene-...) Show SMILES Cc1c(OS(=O)(=O)c2ccccc2F)cccc1C1CCNCC1 Show InChI InChI=1S/C18H20FNO3S/c1-13-15(14-9-11-20-12-10-14)5-4-7-17(13)23-24(21,22)18-8-3-2-6-16(18)19/h2-8,14,20H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	13.6	-44.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28632 (2-methyl-3-(piperidin-4-yl)phenyl 3-methylbenzene-...) Show SMILES Cc1cccc(c1)S(=O)(=O)Oc1cccc(C2CCNCC2)c1C Show InChI InChI=1S/C19H23NO3S/c1-14-5-3-6-17(13-14)24(21,22)23-19-8-4-7-18(15(19)2)16-9-11-20-12-10-16/h3-8,13,16,20H,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	15.1	-44.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28587 (3-[2-methyl-3-(piperazin-1-yl)phenoxymethyl]benzon...) Show SMILES Cc1c(OCc2cccc(c2)C#N)cccc1N1CCNCC1 Show InChI InChI=1S/C19H21N3O/c1-15-18(22-10-8-21-9-11-22)6-3-7-19(15)23-14-17-5-2-4-16(12-17)13-20/h2-7,12,21H,8-11,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	15.3	-44.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28608 (2-[(3-fluorophenyl)methoxy]-3-methyl-4-(piperidin-...) Show SMILES Cc1c(OCc2cccc(F)c2)nccc1C1CCNCC1 Show InChI InChI=1S/C18H21FN2O/c1-13-17(15-5-8-20-9-6-15)7-10-21-18(13)22-12-14-3-2-4-16(19)11-14/h2-4,7,10-11,15,20H,5-6,8-9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17.8	-44.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28605 (4-{3-[1-(3-chlorophenyl)propoxy]-2-methylphenyl}pi...) Show SMILES CCC(Oc1cccc(C2CCNCC2)c1C)c1cccc(Cl)c1 Show InChI InChI=1S/C21H26ClNO/c1-3-20(17-6-4-7-18(22)14-17)24-21-9-5-8-19(15(21)2)16-10-12-23-13-11-16/h4-9,14,16,20,23H,3,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17.9	-43.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28627 (2-methyl-3-(piperidin-4-yl)phenyl 3-fluorobenzene-...) Show SMILES Cc1c(OS(=O)(=O)c2cccc(F)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C18H20FNO3S/c1-13-17(14-8-10-20-11-9-14)6-3-7-18(13)23-24(21,22)16-5-2-4-15(19)12-16/h2-7,12,14,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	18.4	-44.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28609 (3-methyl-4-(piperidin-4-yl)-2-{[3-(trifluoromethyl...) Show SMILES Cc1c(OCc2cccc(c2)C(F)(F)F)nccc1C1CCNCC1 Show InChI InChI=1S/C19H21F3N2O/c1-13-17(15-5-8-23-9-6-15)7-10-24-18(13)25-12-14-3-2-4-16(11-14)19(20,21)22/h2-4,7,10-11,15,23H,5-6,8-9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	19.1	-44.1	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28625 (2-methyl-3-(piperidin-4-yl)phenyl benzenesulfonate...) Show SMILES Cc1c(OS(=O)(=O)c2ccccc2)cccc1C1CCNCC1 Show InChI InChI=1S/C18H21NO3S/c1-14-17(15-10-12-19-13-11-15)8-5-9-18(14)22-23(20,21)16-6-3-2-4-7-16/h2-9,15,19H,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	19.6	-44.0	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28629 (2-methyl-3-(piperidin-4-yl)phenyl 4-chlorobenzene-...) Show SMILES Cc1c(OS(=O)(=O)c2ccc(Cl)cc2)cccc1C1CCNCC1 Show InChI InChI=1S/C18H20ClNO3S/c1-13-17(14-9-11-20-12-10-14)3-2-4-18(13)23-24(21,22)16-7-5-15(19)6-8-16/h2-8,14,20H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	24.7	-43.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28626 (2-methyl-3-(piperidin-4-yl)phenyl 3-chlorobenzene-...) Show SMILES Cc1c(OS(=O)(=O)c2cccc(Cl)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C18H20ClNO3S/c1-13-17(14-8-10-20-11-9-14)6-3-7-18(13)23-24(21,22)16-5-2-4-15(19)12-16/h2-7,12,14,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	26.1	-43.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28633 (2-methyl-3-(piperidin-4-yl)phenyl 4-methylbenzene-...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Oc1cccc(C2CCNCC2)c1C Show InChI InChI=1S/C19H23NO3S/c1-14-6-8-17(9-7-14)24(21,22)23-19-5-3-4-18(15(19)2)16-10-12-20-13-11-16/h3-9,16,20H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	28.9	-43.0	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28604 (4-{3-[(1R)-1-(3-chlorophenyl)ethoxy]-2-methylpheny...) Show SMILES C[C@@H](Oc1cccc(C2CCNCC2)c1C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H24ClNO/c1-14-19(16-9-11-22-12-10-16)7-4-8-20(14)23-15(2)17-5-3-6-18(21)13-17/h3-8,13,15-16,22H,9-12H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	39.5	-41.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28602 (4-{3-[(1R)-1-(3-fluorophenyl)ethoxy]-2-methylpheny...) Show SMILES C[C@@H](Oc1cccc(C2CCNCC2)c1C)c1cccc(F)c1 |r| Show InChI InChI=1S/C20H24FNO/c1-14-19(16-9-11-22-12-10-16)7-4-8-20(14)23-15(2)17-5-3-6-18(21)13-17/h3-8,13,15-16,22H,9-12H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	39.8	-41.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28598 (4-{3-[(3,4-difluorophenyl)methoxy]-2-methylphenyl}...) Show SMILES Cc1c(OCc2ccc(F)c(F)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C19H21F2NO/c1-13-16(15-7-9-22-10-8-15)3-2-4-19(13)23-12-14-5-6-17(20)18(21)11-14/h2-6,11,15,22H,7-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	42	-41.7	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28592 (1-{2-methyl-3-[(1S)-1-phenylethoxy]phenyl}piperazi...) Show SMILES C[C@H](Oc1cccc(N2CCNCC2)c1C)c1ccccc1 |r| Show InChI InChI=1S/C19H24N2O/c1-15-18(21-13-11-20-12-14-21)9-6-10-19(15)22-16(2)17-7-4-3-5-8-17/h3-10,16,20H,11-14H2,1-2H3/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	45.6	-41.5	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28615 (3-methyl-2-[(1S)-1-phenylethoxy]-4-(piperidin-4-yl...) Show SMILES C[C@H](Oc1nccc(C2CCNCC2)c1C)c1ccccc1 |r| Show InChI InChI=1S/C19H24N2O/c1-14-18(17-8-11-20-12-9-17)10-13-21-19(14)22-15(2)16-6-4-3-5-7-16/h3-7,10,13,15,17,20H,8-9,11-12H2,1-2H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	48.5	-41.7	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28611 (2-[(4-chlorophenyl)methoxy]-3-methyl-4-(piperidin-...) Show SMILES Cc1c(OCc2ccc(Cl)cc2)nccc1C1CCNCC1 Show InChI InChI=1S/C18H21ClN2O/c1-13-17(15-6-9-20-10-7-15)8-11-21-18(13)22-12-14-2-4-16(19)5-3-14/h2-5,8,11,15,20H,6-7,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	50	-41.7	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28590 (1-{3-[(3,4-dichlorophenyl)methoxy]-2-methylphenyl}...) Show SMILES Cc1c(OCc2ccc(Cl)c(Cl)c2)cccc1N1CCNCC1 Show InChI InChI=1S/C18H20Cl2N2O/c1-13-17(22-9-7-21-8-10-22)3-2-4-18(13)23-12-14-5-6-15(19)16(20)11-14/h2-6,11,21H,7-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	61.6	-40.7	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28593 (1-{2-methyl-3-[(1R)-1-phenylethoxy]phenyl}piperazi...) Show SMILES C[C@@H](Oc1cccc(N2CCNCC2)c1C)c1ccccc1 |r| Show InChI InChI=1S/C19H24N2O/c1-15-18(21-13-11-20-12-14-21)9-6-10-19(15)22-16(2)17-7-4-3-5-8-17/h3-10,16,20H,11-14H2,1-2H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	70.7	-40.4	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28597 (4-{2-methyl-3-[(3-methylphenyl)methoxy]phenyl}pipe...) Show SMILES Cc1cccc(COc2cccc(C3CCNCC3)c2C)c1 Show InChI InChI=1S/C20H25NO/c1-15-5-3-6-17(13-15)14-22-20-8-4-7-19(16(20)2)18-9-11-21-12-10-18/h3-8,13,18,21H,9-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	92.5	-39.7	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28591 (1-[2-methyl-3-(pyridin-3-ylmethoxy)phenyl]piperazi...) Show SMILES Cc1c(OCc2cccnc2)cccc1N1CCNCC1 Show InChI InChI=1S/C17H21N3O/c1-14-16(20-10-8-18-9-11-20)5-2-6-17(14)21-13-15-4-3-7-19-12-15/h2-7,12,18H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	126	-39.0	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28596 (3-[2-methyl-3-(piperidin-4-yl)phenoxymethyl]benzon...) Show SMILES Cc1c(OCc2cccc(c2)C#N)cccc1C1CCNCC1 Show InChI InChI=1S/C20H22N2O/c1-15-19(18-8-10-22-11-9-18)6-3-7-20(15)23-14-17-5-2-4-16(12-17)13-21/h2-7,12,18,22H,8-11,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	174	-38.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28618 (2-[(1R)-1-(3-chlorophenyl)ethoxy]-3-methyl-4-(pipe...) Show SMILES C[C@@H](Oc1nccc(C2CCNCC2)c1C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H23ClN2O/c1-13-18(15-6-9-21-10-7-15)8-11-22-19(13)23-14(2)16-4-3-5-17(20)12-16/h3-5,8,11-12,14-15,21H,6-7,9-10H2,1-2H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	208	-38.1	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28599 (4-{3-[(3,4-dichlorophenyl)methoxy]-2-methylphenyl}...) Show SMILES Cc1c(OCc2ccc(Cl)c(Cl)c2)cccc1C1CCNCC1 Show InChI InChI=1S/C19H21Cl2NO/c1-13-16(15-7-9-22-10-8-15)3-2-4-19(13)23-12-14-5-6-17(20)18(21)11-14/h2-6,11,15,22H,7-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	219	-37.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28614 (2-[(2,4-difluorophenyl)methoxy]-3-methyl-4-(piperi...) Show SMILES Cc1c(OCc2ccc(F)cc2F)nccc1C1CCNCC1 Show InChI InChI=1S/C18H20F2N2O/c1-12-16(13-4-7-21-8-5-13)6-9-22-18(12)23-11-14-2-3-15(19)10-17(14)20/h2-3,6,9-10,13,21H,4-5,7-8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	239	-37.8	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28606 (4-{3-[(3-chlorophenyl)methoxy]-2-methylphenyl}pipe...) Show SMILES Cc1c(OCc2cccc(Cl)c2)cccc1C1(O)CCNCC1 Show InChI InChI=1S/C19H22ClNO2/c1-14-17(19(22)8-10-21-11-9-19)6-3-7-18(14)23-13-15-4-2-5-16(20)12-15/h2-7,12,21-22H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>440	>-35.9	n/a	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28610 (2-[(2-chlorophenyl)methoxy]-3-methyl-4-(piperidin-...) Show SMILES Cc1c(OCc2ccccc2Cl)nccc1C1CCNCC1 Show InChI InChI=1S/C18H21ClN2O/c1-13-16(14-6-9-20-10-7-14)8-11-21-18(13)22-12-15-4-2-3-5-17(15)19/h2-5,8,11,14,20H,6-7,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>440	>-36.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28612 (2-[(2-fluorophenyl)methoxy]-3-methyl-4-(piperidin-...) Show SMILES Cc1c(OCc2ccccc2F)nccc1C1CCNCC1 Show InChI InChI=1S/C18H21FN2O/c1-13-16(14-6-9-20-10-7-14)8-11-21-18(13)22-12-15-4-2-3-5-17(15)19/h2-5,8,11,14,20H,6-7,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>440	>-36.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Pfizer					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5
					More data for this Ligand-Target Pair

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