Compile Data Set for Download or QSAR

Found 33 hits Enz. Inhib. hit(s) with all data for entry = 519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM275767 (US10071110, Compound CDV | US10071110, Compound Ci...) Show SMILES Nc1ccn(CC(CO)OCP(O)(O)=O)c(=O)n1 Show InChI InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275786 (US10071110, Compound 1-O-octadecylpropanediol-2-cC...) Show SMILES CCCCCCCCCCCCCCCCOCC(CO)OP1(=O)COC(CO1)n1ccc(N)nc1=O Show InChI InChI=1S/C26H48N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-33-20-23(19-30)36-37(32)22-34-25(21-35-37)29-17-16-24(27)28-26(29)31/h16-17,23,25,30H,2-15,18-22H2,1H3,(H2,27,28,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C27H50N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-33-20-16-21-35-37(32)24-34-25(23-36-37)22-30-18-17-26(28)29-27(30)31/h17-18,25H,2-16,19-24H2,1H3,(H2,28,29,31)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM50001103 ((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...) Show SMILES Nc1ncnc2n(CCOCP(O)(O)=O)cnc12 Show InChI InChI=1S/C8H12N5O4P/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-17-5-18(14,15)16/h3-4H,1-2,5H2,(H2,9,10,11)(H2,14,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275767 (US10071110, Compound CDV | US10071110, Compound Ci...) Show SMILES Nc1ccn(CC(CO)OCP(O)(O)=O)c(=O)n1 Show InChI InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275768 (CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...) Show SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1 Show InChI InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	470	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275773 (US10071110, Compound 1-O-hexadecylpropanediol-3-CD...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP(O)(=O)COC(CO)Cn1ccc(N)nc1=O Show InChI InChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C27H50N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-33-20-16-21-35-37(32)24-34-25(23-36-37)22-30-18-17-26(28)29-27(30)31/h17-18,25H,2-16,19-24H2,1H3,(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275775 (US10071110, Compound 1-O-octadecylpropanediol-3-CD...) Show SMILES CCCCCCCCCCCCCCCCCCOCCCOP(O)(=O)COC(CO)Cn1ccc(N)nc1=O Show InChI InChI=1S/C29H56N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-37-22-18-23-39-40(35,36)26-38-27(25-33)24-32-20-19-28(30)31-29(32)34/h19-20,27,33H,2-18,21-26H2,1H3,(H,35,36)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275776 (US10071110, Compound 1-O-octadecylpropanediol-3-cC...) Show SMILES CCCCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C29H54N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-35-22-18-23-37-39(34)26-36-27(25-38-39)24-32-20-19-28(30)31-29(32)33/h19-20,27H,2-18,21-26H2,1H3,(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275777 (US10071110, Compound 1-O-octadecylethanediol-2-CDV) Show SMILES CCCCCCCCCCCCCCCCCCOCCOP(O)(=O)COC(CO)Cn1ccc(N)nc1=O Show InChI InChI=1S/C28H54N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-36-21-22-38-39(34,35)25-37-26(24-32)23-31-19-18-27(29)30-28(31)33/h18-19,26,32H,2-17,20-25H2,1H3,(H,34,35)(H2,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275778 (US10071110, Compound 1-O-octadecylethanediol-2-cCD...) Show SMILES CCCCCCCCCCCCCCCCCCOCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C28H52N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-34-21-22-36-38(33)25-35-26(24-37-38)23-31-19-18-27(29)30-28(31)32/h18-19,26H,2-17,20-25H2,1H3,(H2,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275779 (US10071110, Compound Hexadecyl-cCDV) Show SMILES CCCCCCCCCCCCCCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C24H44N3O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-31-33(29)21-30-22(20-32-33)19-27-17-16-23(25)26-24(27)28/h16-17,22H,2-15,18-21H2,1H3,(H2,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50001103 ((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...) Show SMILES Nc1ncnc2n(CCOCP(O)(O)=O)cnc12 Show InChI InChI=1S/C8H12N5O4P/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-17-5-18(14,15)16/h3-4H,1-2,5H2,(H2,9,10,11)(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275780 (US10071110, Compound 1-O-hexadecylpropanediol-3-AD...) Show SMILES CCCCCCCCCCCCCCCCCCOCCCOP(O)(=O)COCCn1cnc2c(N)ncnc12 Show InChI InChI=1S/C29H54N5O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-37-21-18-22-39-40(35,36)26-38-23-19-34-25-33-27-28(30)31-24-32-29(27)34/h24-25H,2-23,26H2,1H3,(H,35,36)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275781 (US10071110, Compound 1-O-octadecyl-sn-glycero-3-AD...) Show SMILES CCCCCCCCCCCCCCCCCCOC[C@H](CO)OP(O)(=O)COCCn1cnc2c(N)ncnc12 Show InChI InChI=1S/C29H54N5O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-38-22-26(21-35)40-41(36,37)25-39-20-18-34-24-33-27-28(30)31-23-32-29(27)34/h23-24,26,35H,2-22,25H2,1H3,(H,36,37)(H2,30,31,32)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275767 (US10071110, Compound CDV | US10071110, Compound Ci...) Show SMILES Nc1ccn(CC(CO)OCP(O)(O)=O)c(=O)n1 Show InChI InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275767 (US10071110, Compound CDV | US10071110, Compound Ci...) Show SMILES Nc1ccn(CC(CO)OCP(O)(O)=O)c(=O)n1 Show InChI InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275768 (CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...) Show SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1 Show InChI InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	970	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275768 (CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...) Show SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1 Show InChI InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C27H50N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-33-20-16-21-35-37(32)24-34-25(23-36-37)22-30-18-17-26(28)29-27(30)31/h17-18,25H,2-16,19-24H2,1H3,(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C27H50N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-33-20-16-21-35-37(32)24-34-25(23-36-37)22-30-18-17-26(28)29-27(30)31/h17-18,25H,2-16,19-24H2,1H3,(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<30	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM50002692 ((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...) Show SMILES Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM50001103 ((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...) Show SMILES Nc1ncnc2n(CCOCP(O)(O)=O)cnc12 Show InChI InChI=1S/C8H12N5O4P/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-17-5-18(14,15)16/h3-4H,1-2,5H2,(H2,9,10,11)(H2,14,15,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275783 (US10071110, Compound HDP-ADV) Show SMILES CCCCCCCCCCCCCCCCOCCCOP(O)(=O)COCn1cnc2c(N)ncnc12 Show InChI InChI=1S/C26H48N5O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-34-18-16-19-36-37(32,33)23-35-22-31-21-30-24-25(27)28-20-29-26(24)31/h20-21H,2-19,22-23H2,1H3,(H,32,33)(H2,27,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM31915 (CDV | Cidofovir | HPMPC | US10071110, Compound Cid...) Show SMILES Nc1ccn(C[C@@H](CO)OCP(O)(O)=O)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275768 (CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...) Show SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1 Show InChI InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275773 (US10071110, Compound 1-O-hexadecylpropanediol-3-CD...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP(O)(=O)COC(CO)Cn1ccc(N)nc1=O Show InChI InChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) Show SMILES CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C27H50N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-33-20-16-21-35-37(32)24-34-25(23-36-37)22-30-18-17-26(28)29-27(30)31/h17-18,25H,2-16,19-24H2,1H3,(H2,28,29,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275775 (US10071110, Compound 1-O-octadecylpropanediol-3-CD...) Show SMILES CCCCCCCCCCCCCCCCCCOCCCOP(O)(=O)COC(CO)Cn1ccc(N)nc1=O Show InChI InChI=1S/C29H56N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-37-22-18-23-39-40(35,36)26-38-27(25-33)24-32-20-19-28(30)31-29(32)34/h19-20,27,33H,2-18,21-26H2,1H3,(H,35,36)(H2,30,31,34)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275776 (US10071110, Compound 1-O-octadecylpropanediol-3-cC...) Show SMILES CCCCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 Show InChI InChI=1S/C29H54N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-35-22-18-23-37-39(34)26-36-27(25-38-39)24-32-20-19-28(30)31-29(32)33/h19-20,27H,2-18,21-26H2,1H3,(H2,30,31,33)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM275785 (US10071110, Compound 1-O-octadecylpropanediol-2-CD...) Show SMILES CCCCCCCCCCCCCCCCOCC(CO)OP(O)(=O)COC(CO)Cn1ccc(N)nc1=O Show InChI InChI=1S/C27H52N3O8P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-36-22-25(21-32)38-39(34,35)23-37-24(20-31)19-30-17-16-26(28)29-27(30)33/h16-17,24-25,31-32H,2-15,18-23H2,1H3,(H,34,35)(H2,28,29,33)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM275768 (CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...) Show SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1 Show InChI InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	470	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair