Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285634 (3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.488 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285598 (3-(3-chloro-4-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.669 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285537 (3-(4-chloro-3-fluoro-phenyl)-N-cyclopropyl-imidazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.51 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285634 (3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.59 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285538 (N-cyclopropyl-3-(3,4-di-chlorophenyl)imidazo[1,2-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285534 (3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.89 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285572 (3-(4-chloro-3-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.97 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Homo sapiens (Human)) | BDBM285598 (3-(3-chloro-4-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Homo sapiens (Human)) | BDBM285534 (3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.35 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285534 (3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.77 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285598 (3-(3-chloro-4-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.82 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285572 (3-(4-chloro-3-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.91 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285568 (N-cyclopropyl-3-(3-fluoro-4-methylphenyl)imidazo[1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285556 (3-(4-chloro-3-fluorophenyl)-N-propylimidazo[1,2-b]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285537 (3-(4-chloro-3-fluoro-phenyl)-N-cyclopropyl-imidazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285536 (3-(4-Chloro-2,5-difluorophenyl)-N-cyclopropylimida...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285574 (US10077269, Example 47 | US10669279, Example 47 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285571 (3-(4-chloro-3-fluorophenyl)-N-(2,2-difluorocyclopr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285576 (US10077269, Example 49 | US10669279, Example 49 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285626 (3-(4-chloro-2,5-difluoro-phenyl)-N-ethylimidazo[1,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.58 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285540 (US10077269, Example 13 | US10669279, Example 13 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.63 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Homo sapiens (Human)) | BDBM285634 (3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.69 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285551 (4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.04 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285556 (3-(4-chloro-3-fluorophenyl)-N-propylimidazo[1,2-b]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.05 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285540 (US10077269, Example 13 | US10669279, Example 13 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285612 (3-(4-chloro-3-fluorophenyl)-N-(1H-pyrazol-4-yl)imi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285613 (US10077269, Example 83 | US10669279, Example 83 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.39 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285603 (US10077269, Example 76 | US10669279, Example 76 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285627 (3-(4-chloro-5-fluoro-2-methylphenyl)-N-(propan-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285622 (3-(4-cyano-2,5-difluorophenyl)-N-cyclopropylimidaz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.52 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285547 (4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.74 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285616 (US10077269, Example 86 | US10669279, Example 86 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285602 (N-cyclopropyl-3-[2-(difluoro-methoxy)pyridin-4-yl]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285613 (US10077269, Example 83 | US10669279, Example 83 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.21 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285547 (4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Homo sapiens (Human)) | BDBM285537 (3-(4-chloro-3-fluoro-phenyl)-N-cyclopropyl-imidazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.84 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285563 (3-(3-chlorophenyl)-N-cyclopropylimidazo[1,2-b]pyri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285603 (US10077269, Example 76 | US10669279, Example 76 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285574 (US10077269, Example 47 | US10669279, Example 47 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.37 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285616 (US10077269, Example 86 | US10669279, Example 86 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.72 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285614 (US10077269, Example 84 | US10669279, Example 84 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.84 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285611 (3-(4-chloro-3-fluorophenyl)-N-ethylimidazo[1,2-b]p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.86 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285568 (N-cyclopropyl-3-(3-fluoro-4-methylphenyl)imidazo[1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.05 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285611 (3-(4-chloro-3-fluorophenyl)-N-ethylimidazo[1,2-b]p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.34 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285602 (N-cyclopropyl-3-[2-(difluoro-methoxy)pyridin-4-yl]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Homo sapiens (Human)) | BDBM285536 (3-(4-Chloro-2,5-difluorophenyl)-N-cyclopropylimida...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285595 (3-(4-chloro-2-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285529 (3-(4-Chlorophenyl)-N-cyclopropylimidazo[1,2-b]pyri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Homo sapiens (Human)) | BDBM285557 (3-(4-chlorophenyl)-N-(2-methylcyclopropyl)imidazo[...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Homo sapiens (Human)) | BDBM285572 (3-(4-chloro-3-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD... | US Patent US10077269 (2018) BindingDB Entry DOI: 10.7270/Q2P84DX5 | |||||||||||
More data for this Ligand-Target Pair |
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