Compile Data Set for Download or QSAR

Found 350 hits Enz. Inhib. hit(s) with all data for entry = 1065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM306556 ((1R,8S)-N-[(4-carbamimidoyl- 2,6-dimethyl-phenyl)m...) Show SMILES Cc1cc(cc(C)c1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-c1ccc(F)cc1F)C(N)=N |r| Show InChI InChI=1S/C31H25F2N3O2/c1-15-9-19(30(34)35)10-16(2)26(15)14-36-31(37)18-4-7-23-25(12-18)29-24-11-17(3-6-22(24)28(23)38-29)21-8-5-20(32)13-27(21)33/h3-13,28-29H,14H2,1-2H3,(H3,34,35)(H,36,37)/t28-,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.741	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306637 ((1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES NC(=N)c1cc(F)c(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(ccc45)C4CC4)c3c2)c(F)c1 |r| Show InChI InChI=1S/C26H21F2N3O2/c27-21-9-15(25(29)30)10-22(28)20(21)11-31-26(32)14-4-6-17-19(8-14)24-18-7-13(12-1-2-12)3-5-16(18)23(17)33-24/h3-10,12,23-24H,1-2,11H2,(H3,29,30)(H,31,32)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.759	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306613 ((1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES NC(=N)c1cc(F)c(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2F)c(F)c1 |r| Show InChI InChI=1S/C29H19F4N3O2/c30-16-3-6-17(25(33)11-16)13-1-4-18-20(7-13)27-21-8-14(2-5-19(21)26(18)38-27)29(37)36-12-22-23(31)9-15(28(34)35)10-24(22)32/h1-11,26-27H,12H2,(H3,34,35)(H,36,37)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.759	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306663 ((1S,8R)-N-[(4-carbamimidoyl- phenyl)methyl]-12-(3,...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(ccc45)N4CC(F)(F)C4)c3c2)cc1 |r| Show InChI InChI=1S/C26H22F2N4O2/c27-26(28)12-32(13-26)17-6-8-19-21(10-17)23-20-9-16(5-7-18(20)22(19)34-23)25(33)31-11-14-1-3-15(4-2-14)24(29)30/h1-10,22-23H,11-13H2,(H3,29,30)(H,31,33)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306528 ((+-)-N-[(4-carbamimidoylphenyl) methyl]-12-(2,4- d...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3C4OC(c3c2)c2cc(ccc42)-c2ccc(F)cc2F)cc1 Show InChI InChI=1S/C29H21F2N3O2/c30-19-7-10-20(25(31)13-19)17-5-8-21-23(11-17)27-24-12-18(6-9-22(24)26(21)36-27)29(35)34-14-15-1-3-16(4-2-15)28(32)33/h1-13,26-27H,14H2,(H3,32,33)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306668 ((1S,8R)-N-[(4-carbamimidoyl-2- methylphenyl)-methy...) Show SMILES Cc1cc(ccc1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-n1cccn1)C(N)=N |r| Show InChI InChI=1S/C27H23N5O2/c1-15-11-16(26(28)29)3-4-18(15)14-30-27(33)17-5-7-20-22(12-17)25-23-13-19(32-10-2-9-31-32)6-8-21(23)24(20)34-25/h2-13,24-25H,14H2,1H3,(H3,28,29)(H,30,33)/t24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306708 ((1S,8R)-N-[(4-carbamimidoyl- phenyl)methyl]-11,12-...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(C3CC3)c(cc42)C2CC2)cc1 |r| Show InChI InChI=1S/C29H27N3O2/c30-28(31)18-3-1-15(2-4-18)14-32-29(33)19-9-10-20-23(11-19)27-25-13-22(17-7-8-17)21(16-5-6-16)12-24(25)26(20)34-27/h1-4,9-13,16-17,26-27H,5-8,14H2,(H3,30,31)(H,32,33)/t26-,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306535 ((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)meth...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2[C@H]3O[C@H](c4cc(Cn5cc(F)cn5)ccc34)c2c1 |r| Show InChI InChI=1S/C27H24FN5O2/c1-14-7-24(29)32-15(2)23(14)11-30-27(34)17-4-6-20-22(9-17)26-21-8-16(3-5-19(21)25(20)35-26)12-33-13-18(28)10-31-33/h3-10,13,25-26H,11-12H2,1-2H3,(H2,29,32)(H,30,34)/t25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306536 ((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)meth...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2[C@H]3O[C@H](c4cc(Cn5cc(Cl)cn5)ccc34)c2c1 |r| Show InChI InChI=1S/C27H24ClN5O2/c1-14-7-24(29)32-15(2)23(14)11-30-27(34)17-4-6-20-22(9-17)26-21-8-16(3-5-19(21)25(20)35-26)12-33-13-18(28)10-31-33/h3-10,13,25-26H,11-12H2,1-2H3,(H2,29,32)(H,30,34)/t25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306538 ((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)meht...) Show SMILES Cc1cnn(Cc2ccc3[C@@H]4O[C@H](c3c2)c2cc(ccc42)C(=O)NCc2c(C)cc(N)nc2C)c1 |r| Show InChI InChI=1S/C28H27N5O2/c1-15-11-31-33(13-15)14-18-4-6-20-22(9-18)27-23-10-19(5-7-21(23)26(20)35-27)28(34)30-12-24-16(2)8-25(29)32-17(24)3/h4-11,13,26-27H,12,14H2,1-3H3,(H2,29,32)(H,30,34)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306558 ((1R,8S)-N-[(4- carbamimidoylphenyl) methyl]-12-(4-...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C29H22FN3O2/c30-21-9-5-17(6-10-21)19-7-11-22-24(13-19)27-25-14-20(8-12-23(25)26(22)35-27)29(34)33-15-16-1-3-18(4-2-16)28(31)32/h1-14,26-27H,15H2,(H3,31,32)(H,33,34)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306559 ((1R,8S)-N-[(4- carbamimidoylphenyl) methyl]-12-(2,...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2F)cc1 |r| Show InChI InChI=1S/C29H21F2N3O2/c30-19-7-10-20(25(31)13-19)17-5-8-21-23(11-17)27-24-12-18(6-9-22(24)26(21)36-27)29(35)34-14-15-1-3-16(4-2-15)28(32)33/h1-13,26-27H,14H2,(H3,32,33)(H,34,35)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306565 ((1R,8S)-N-{[6-amino-2-methyl- 4-(propan-2-yl)-pyri...) Show SMILES CC(C)c1cc(N)nc(C)c1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-c1ccc(F)cc1F |r| Show InChI InChI=1S/C31H27F2N3O2/c1-15(2)23-13-28(34)36-16(3)26(23)14-35-31(37)18-5-8-22-25(11-18)30-24-10-17(4-7-21(24)29(22)38-30)20-9-6-19(32)12-27(20)33/h4-13,15,29-30H,14H2,1-3H3,(H2,34,36)(H,35,37)/t29-,30+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306581 ((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)meth...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2[C@H]3O[C@H](c4cc(Cn5ccccc5=O)ccc34)c2c1 |r| Show InChI InChI=1S/C29H26N4O3/c1-16-11-25(30)32-17(2)24(16)14-31-29(35)19-7-9-21-23(13-19)28-22-12-18(6-8-20(22)27(21)36-28)15-33-10-4-3-5-26(33)34/h3-13,27-28H,14-15H2,1-2H3,(H2,30,32)(H,31,35)/t27-,28+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306620 ((1S,8R)-N-[(4-carbamimidoyl- phenyl)methyl]-12-[(3...) Show SMILES CN(c1ccc2[C@@H]3O[C@H](c2c1)c1cc(ccc31)C(=O)NCc1ccc(cc1)C(N)=N)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C30H25ClN4O2/c1-35(21-4-2-3-20(31)14-21)22-10-12-24-26(15-22)28-25-13-19(9-11-23(25)27(24)37-28)30(36)34-16-17-5-7-18(8-6-17)29(32)33/h2-15,27-28H,16H2,1H3,(H3,32,33)(H,34,36)/t27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306642 ((1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES CC(=C)c1ccc2[C@@H]3O[C@H](c2c1)c1cc(ccc31)C(=O)NCc1c(F)cc(cc1F)C(N)=N |r| Show InChI InChI=1S/C26H21F2N3O2/c1-12(2)13-3-5-16-18(7-13)24-19-8-14(4-6-17(19)23(16)33-24)26(32)31-11-20-21(27)9-15(25(29)30)10-22(20)28/h3-10,23-24H,1,11H2,2H3,(H3,29,30)(H,31,32)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306647 ((1R,8S)-N-[(4-carbamimidoyl- 2-fluorophenyl)-methy...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccccc2F)c(F)c1 |r| Show InChI InChI=1S/C29H21F2N3O2/c30-24-4-2-1-3-19(24)15-7-9-20-22(11-15)27-23-12-17(8-10-21(23)26(20)36-27)29(35)34-14-18-6-5-16(28(32)33)13-25(18)31/h1-13,26-27H,14H2,(H3,32,33)(H,34,35)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306648 ((1R,8S)-N-[(4-carbamimidoyl- 2-fluorophenyl)-methy...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2F)c(F)c1 |r| Show InChI InChI=1S/C29H20F3N3O2/c30-18-5-8-19(25(32)12-18)14-3-6-20-22(9-14)27-23-10-16(4-7-21(23)26(20)37-27)29(36)35-13-17-2-1-15(28(33)34)11-24(17)31/h1-12,26-27H,13H2,(H3,33,34)(H,35,36)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306652 ((1R,8S)-N-((4-carbamimidoyl- 2,6-difluorophenyl)me...) Show SMILES NC(=N)c1cc(F)c(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(CCC(F)(F)F)ccc45)c3c2)c(F)c1 |r| Show InChI InChI=1S/C26H20F5N3O2/c27-20-9-14(24(32)33)10-21(28)19(20)11-34-25(35)13-2-4-16-18(8-13)23-17-7-12(5-6-26(29,30)31)1-3-15(17)22(16)36-23/h1-4,7-10,22-23H,5-6,11H2,(H3,32,33)(H,34,35)/t22-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306658 ((1R,8S)-N-[(4-carbamimidoyl-2- fluorophenyl)-methy...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(ccc45)C4CC4)c3c2)c(F)c1 |r| Show InChI InChI=1S/C26H22FN3O2/c27-22-11-15(25(28)29)3-4-17(22)12-30-26(31)16-6-8-19-21(10-16)24-20-9-14(13-1-2-13)5-7-18(20)23(19)32-24/h3-11,13,23-24H,1-2,12H2,(H3,28,29)(H,30,31)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306662 ((1R,8S)-N-[(4-carbamimidoyl- 2-methylpheny])-methy...) Show SMILES Cc1cc(ccc1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-c1ccc(F)cc1F)C(N)=N |r| Show InChI InChI=1S/C30H23F2N3O2/c1-15-10-17(29(33)34)2-3-19(15)14-35-30(36)18-5-8-23-25(12-18)28-24-11-16(4-7-22(24)27(23)37-28)21-9-6-20(31)13-26(21)32/h2-13,27-28H,14H2,1H3,(H3,33,34)(H,35,36)/t27-,28+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306685 ((1R,8S)-N-[(4-carbamimidoyl- 2-fluorophenyl)-methy...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2)c(F)c1 |r| Show InChI InChI=1S/C29H21F2N3O2/c30-20-7-3-15(4-8-20)16-5-9-21-23(11-16)27-24-12-18(6-10-22(24)26(21)36-27)29(35)34-14-19-2-1-17(28(32)33)13-25(19)31/h1-13,26-27H,14H2,(H3,32,33)(H,34,35)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306686 ((1R,8S)-N-[(4-carbamimidoyl- 2,6-dimethyl-phenyl)m...) Show SMILES Cc1cc(cc(C)c1CNC(=O)c1ccc2[C@H]3O[C@H](c4cc(ccc34)C3CC3)c2c1)C(N)=N |r| Show InChI InChI=1S/C28H27N3O2/c1-14-9-19(27(29)30)10-15(2)24(14)13-31-28(32)18-6-8-21-23(12-18)26-22-11-17(16-3-4-16)5-7-20(22)25(21)33-26/h5-12,16,25-26H,3-4,13H2,1-2H3,(H3,29,30)(H,31,32)/t25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306703 ((1S,8R)-N-[(4- carbamimidoylphenyl) methyl]-11,12-...) Show SMILES CCc1cc2[C@@H]3O[C@H](c2cc1CC)c1cc(ccc31)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C27H27N3O2/c1-3-16-11-22-23(12-17(16)4-2)25-21-13-19(9-10-20(21)24(22)32-25)27(31)30-14-15-5-7-18(8-6-15)26(28)29/h5-13,24-25H,3-4,14H2,1-2H3,(H3,28,29)(H,30,31)/t24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306544 ((1R,8S)-N-[(4- carbamimidoylphenyl) methyl]-12-(2-...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccccc2F)cc1 |r| Show InChI InChI=1S/C29H22FN3O2/c30-25-4-2-1-3-20(25)18-9-11-21-23(13-18)27-24-14-19(10-12-22(24)26(21)35-27)29(34)33-15-16-5-7-17(8-6-16)28(31)32/h1-14,26-27H,15H2,(H3,31,32)(H,33,34)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.74	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306671 ((+-)-N-[(4-carbamimidoylphenyl) methyl]-11,12-diet...) Show SMILES CCc1cc2C3OC(c2cc1CC)c1cc(ccc31)C(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C27H27N3O2/c1-3-16-11-22-23(12-17(16)4-2)25-21-13-19(9-10-20(21)24(22)32-25)27(31)30-14-15-5-7-18(8-6-15)26(28)29/h5-13,24-25H,3-4,14H2,1-2H3,(H3,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.82	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306490 ((+-)-N-[(6-amino-4-methoxy-2- methylpyridin-3-yl)m...) Show SMILES COc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c4cc(Cn5cc(C)cn5)ccc34)c2c1 Show InChI InChI=1S/C28H27N5O3/c1-15-11-31-33(13-15)14-17-4-6-19-21(8-17)27-22-9-18(5-7-20(22)26(19)36-27)28(34)30-12-23-16(2)32-25(29)10-24(23)35-3/h4-11,13,26-27H,12,14H2,1-3H3,(H2,29,32)(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306574 ((1S,8R)-N-[(4- carbamimidoylphenyl)methyl]- 12-(5-...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(Cl)s2)cc1 |r| Show InChI InChI=1S/C27H20ClN3O2S/c28-23-10-9-22(34-23)16-5-7-18-20(11-16)25-21-12-17(6-8-19(21)24(18)33-25)27(32)31-13-14-1-3-15(4-2-14)26(29)30/h1-12,24-25H,13H2,(H3,29,30)(H,31,32)/t24-,25+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306593 ((1S,8R)-N-[(4-carbamimidoyl- phenyl)methyl]-12-(py...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(ccc45)N4CCCC4)c3c2)cc1 |r| Show InChI InChI=1S/C27H26N4O2/c28-26(29)17-5-3-16(4-6-17)15-30-27(32)18-7-9-20-22(13-18)25-23-14-19(31-11-1-2-12-31)8-10-21(23)24(20)33-25/h3-10,13-14,24-25H,1-2,11-12,15H2,(H3,28,29)(H,30,32)/t24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306616 ((1R,8S)-N-[(4- carbamimidoylphenyl) methyl]-12- cy...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(ccc45)C4CC4)c3c2)cc1 |r| Show InChI InChI=1S/C26H23N3O2/c27-25(28)16-3-1-14(2-4-16)13-29-26(30)18-8-10-20-22(12-18)24-21-11-17(15-5-6-15)7-9-19(21)23(20)31-24/h1-4,7-12,15,23-24H,5-6,13H2,(H3,27,28)(H,29,30)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306632 ((1S,8R)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES NC(=N)c1cc(F)c(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2nccs2)c(F)c1 |r| Show InChI InChI=1S/C26H18F2N4O2S/c27-20-9-14(24(29)30)10-21(28)19(20)11-32-25(33)12-1-3-15-17(7-12)23-18-8-13(26-31-5-6-35-26)2-4-16(18)22(15)34-23/h1-10,22-23H,11H2,(H3,29,30)(H,32,33)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306654 ((1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES CC(C)c1ccc2[C@@H]3O[C@H](c2c1)c1cc(ccc31)C(=O)NCc1c(F)cc(cc1F)C(N)=N |r| Show InChI InChI=1S/C26H23F2N3O2/c1-12(2)13-3-5-16-18(7-13)24-19-8-14(4-6-17(19)23(16)33-24)26(32)31-11-20-21(27)9-15(25(29)30)10-22(20)28/h3-10,12,23-24H,11H2,1-2H3,(H3,29,30)(H,31,32)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306492 ((+-)-N-[(6-amino-4-ethoxy-2- methylpyridin-3-yl)me...) Show SMILES CCOc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c4cc(Cn5cc(C)cn5)ccc34)c2c1 Show InChI InChI=1S/C29H29N5O3/c1-4-36-25-11-26(30)33-17(3)24(25)13-31-29(35)19-6-8-21-23(10-19)28-22-9-18(5-7-20(22)27(21)37-28)15-34-14-16(2)12-32-34/h5-12,14,27-28H,4,13,15H2,1-3H3,(H2,30,33)(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306643 ((1S,8R)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES NC(=N)c1cc(F)c(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-n2cccn2)c(F)c1 |r| Show InChI InChI=1S/C26H19F2N5O2/c27-21-9-14(25(29)30)10-22(28)20(21)12-31-26(34)13-2-4-16-18(8-13)24-19-11-15(33-7-1-6-32-33)3-5-17(19)23(16)35-24/h1-11,23-24H,12H2,(H3,29,30)(H,31,34)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.45	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306678 ((+-)-N-[(6-amino-2,4-dimethyl- pyridin-3-yl)methyl...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc(c(C=C)cc31)-c1ccc(F)cc1F Show InChI InChI=1S/C31H25F2N3O2/c1-4-17-10-24-25(13-22(17)20-8-6-19(32)12-27(20)33)30-23-11-18(5-7-21(23)29(24)38-30)31(37)35-14-26-15(2)9-28(34)36-16(26)3/h4-13,29-30H,1,14H2,2-3H3,(H2,34,36)(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306497 ((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)-met...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-c1ccc(Cl)cc1C#N |r| Show InChI InChI=1S/C30H23ClN4O2/c1-15-9-27(33)35-16(2)26(15)14-34-30(36)18-4-7-23-25(12-18)29-24-11-17(3-6-22(24)28(23)37-29)21-8-5-20(31)10-19(21)13-32/h3-12,28-29H,14H2,1-2H3,(H2,33,35)(H,34,36)/t28-,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.02	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306530 ((+-)-N-{[6-amino-2-methyl-4- (propan-2-yl)pyridin-...) Show SMILES CC(C)c1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc(ccc31)-c1ccc(F)cc1F Show InChI InChI=1S/C31H27F2N3O2/c1-15(2)23-13-28(34)36-16(3)26(23)14-35-31(37)18-5-8-22-25(11-18)30-24-10-17(4-7-21(24)29(22)38-30)20-9-6-19(32)12-27(20)33/h4-13,15,29-30H,14H2,1-3H3,(H2,34,36)(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.02	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306475 ((+-)-N-[(6-amino-4-methoxy- 2-methylpyridin-3-yl)m...) Show SMILES COc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c4cc(Cn5cccn5)ccc34)c2c1 Show InChI InChI=1S/C27H25N5O3/c1-15-22(23(34-2)12-24(28)31-15)13-29-27(33)17-5-7-19-21(11-17)26-20-10-16(14-32-9-3-8-30-32)4-6-18(20)25(19)35-26/h3-12,25-26H,13-14H2,1-2H3,(H2,28,31)(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306494 ((+-)-N-[(6-amino-4-ethyl-2- methylpyridin-3-yl)met...) Show SMILES CCc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc(ccc31)-c1ccc(C)cc1C#N Show InChI InChI=1S/C32H28N4O2/c1-4-19-14-29(34)36-18(3)28(19)16-35-32(37)21-7-10-25-27(13-21)31-26-12-20(6-9-24(26)30(25)38-31)23-8-5-17(2)11-22(23)15-33/h5-14,30-31H,4,16H2,1-3H3,(H2,34,36)(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306546 ((+-)-N-[(4-carbamimidoylphenyl) methyl]-12-phenyl-...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3C4OC(c3c2)c2cc(ccc42)-c2ccccc2)cc1 Show InChI InChI=1S/C29H23N3O2/c30-28(31)19-8-6-17(7-9-19)16-32-29(33)21-11-13-23-25(15-21)27-24-14-20(18-4-2-1-3-5-18)10-12-22(24)26(23)34-27/h1-15,26-27H,16H2,(H3,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.57	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306371 ((+-)-N-[(6-amino-2,4- dimethylpyridin-3-yl)- methy...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c4cc(CN5CCC=N5)ccc34)c2c1 |c:28| Show InChI InChI=1S/C27H27N5O2/c1-15-10-24(28)31-16(2)23(15)13-29-27(33)18-5-7-20-22(12-18)26-21-11-17(14-32-9-3-8-30-32)4-6-19(21)25(20)34-26/h4-8,10-12,25-26H,3,9,13-14H2,1-2H3,(H2,28,31)(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306672 ((+-)-N-[(4-carbamimidoyl- phenyl)methyl]-11,12- di...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3C4OC(c3c2)c2cc(C3CC3)c(cc42)C2CC2)cc1 Show InChI InChI=1S/C29H27N3O2/c30-28(31)18-3-1-15(2-4-18)14-32-29(33)19-9-10-20-23(11-19)27-25-13-22(17-7-8-17)21(16-5-6-16)12-24(25)26(20)34-27/h1-4,9-13,16-17,26-27H,5-8,14H2,(H3,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306604 ((1R,8S)-N-{[6-amino-2-methyl-4- (oxan-4-yl)pyridin...) Show SMILES Cc1nc(N)cc(C2CCOCC2)c1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-c1ccc(F)cc1F |r| Show InChI InChI=1S/C33H29F2N3O3/c1-17-28(25(15-30(36)38-17)18-8-10-40-11-9-18)16-37-33(39)20-3-6-24-27(13-20)32-26-12-19(2-5-23(26)31(24)41-32)22-7-4-21(34)14-29(22)35/h2-7,12-15,18,31-32H,8-11,16H2,1H3,(H2,36,38)(H,37,39)/t31-,32+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306625 ((1R,8S)-N-[(6-carbamimidoyl- pyridin-3-yl)-methyl]...) Show SMILES NC(=N)c1ccc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2F)cn1 |r| Show InChI InChI=1S/C28H20F2N4O2/c29-17-4-7-18(23(30)11-17)15-2-5-19-21(9-15)26-22-10-16(3-6-20(22)25(19)36-26)28(35)34-13-14-1-8-24(27(31)32)33-12-14/h1-12,25-26H,13H2,(H3,31,32)(H,34,35)/t25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306498 ((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)-met...) Show SMILES Cc1ccc(-c2ccc3[C@@H]4O[C@@H](c5cc(ccc45)C(=O)NCc4c(C)cc(N)nc4C)c3c2)c(c1)C#N |r| Show InChI InChI=1S/C31H26N4O2/c1-16-4-7-22(21(10-16)14-32)19-5-8-23-25(12-19)30-26-13-20(6-9-24(26)29(23)37-30)31(36)34-15-27-17(2)11-28(33)35-18(27)3/h4-13,29-30H,15H2,1-3H3,(H2,33,35)(H,34,36)/t29-,30+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306691 ((1S,8R)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...) Show SMILES NC(=N)c1cc(F)c(CNC(=O)c2ccc3[C@H]4O[C@H](c5cc(ccc45)N4CCS(=O)(=O)CC4)c3c2)c(F)c1 |r| Show InChI InChI=1S/C27H24F2N4O4S/c28-22-10-15(26(30)31)11-23(29)21(22)13-32-27(34)14-1-3-17-19(9-14)25-20-12-16(2-4-18(20)24(17)37-25)33-5-7-38(35,36)8-6-33/h1-4,9-12,24-25H,5-8,13H2,(H3,30,31)(H,32,34)/t24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306704 ((+-)-N-[(4- carbamimidoylphenyl) methyl]-6-fluoro-...) Show SMILES Cc1cc(cc2C3OC(c12)c1c3cc(cc1F)C(=O)NCc1ccc(cc1)C(N)=N)-c1ccc(F)cc1 Show InChI InChI=1S/C30H23F2N3O2/c1-15-10-19(17-6-8-21(31)9-7-17)11-22-25(15)28-26-23(27(22)37-28)12-20(13-24(26)32)30(36)35-14-16-2-4-18(5-3-16)29(33)34/h2-13,27-28H,14H2,1H3,(H3,33,34)(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306693 ((1R,8S)-N-[(4-carbamimidoyl- 3-methoxyphenyl)-meth...) Show SMILES COc1cc(CNC(=O)c2ccc3[C@H]4O[C@@H](c3c2)c2cc(ccc42)-c2ccc(F)cc2F)ccc1C(N)=N |r| Show InChI InChI=1S/C30H23F2N3O3/c1-37-26-10-15(2-6-22(26)29(33)34)14-35-30(36)17-4-8-21-24(12-17)28-23-11-16(3-7-20(23)27(21)38-28)19-9-5-18(31)13-25(19)32/h2-13,27-28H,14H2,1H3,(H3,33,34)(H,35,36)/t27-,28+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.89	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306426 ((+-)-N-[(6-amino-2,4- dimethylpyridin-3-yl)methyl]...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc(ccc31)-c1ccc(F)cc1C#N Show InChI InChI=1S/C30H23FN4O2/c1-15-9-27(33)35-16(2)26(15)14-34-30(36)18-4-7-23-25(12-18)29-24-11-17(3-6-22(24)28(23)37-29)21-8-5-20(31)10-19(21)13-32/h3-12,28-29H,14H2,1-2H3,(H2,33,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM306641 ((1S,8R)-N-[(4- carbamimidoylphenyl) methyl]-12-(2-...) Show SMILES CC(C)(F)c1ccc2[C@@H]3O[C@@H](c4cc(ccc34)C(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C26H24FN3O2/c1-26(2,27)17-8-10-19-21(12-17)23-20-11-16(7-9-18(20)22(19)32-23)25(31)30-13-14-3-5-15(6-4-14)24(28)29/h3-12,22-23H,13H2,1-2H3,(H3,28,29)(H,30,31)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
					More data for this Ligand-Target Pair

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