Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM50095470 (CHEMBL3590474 | US10155765, Example 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311516 (5-{[(3R,4R)-3- aminotetrahydro-2H- pyran-4-yl]amin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312059 (5-{[(1R,2S)-2-Aminocyclohexyl]amino}-N-(3-carbamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311525 (5-[(2- aminoethyl)amino]-N- (3-carbamoyl-1-pyridin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311563 (2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-(3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311520 (5-{[cis-2- aminocyclohexyl]amino}- N-(3-carbamoyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312068 (2-[(2-Aminoethyl)amino]-N-(3-carbamoyl-1-methyl-1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311564 (2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-(3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311533 (5-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311534 (5-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312055 (5-{[cis-2-Aminocyclohexyl]amino}-N-{3-carbamoyl-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311527 (5-[(2- aminocycloheptyl)amino]- N-(3-carbamoyl-1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM50095465 (CHEMBL3590438 | US10155765, Example 28) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311536 (5-{[(1R,2S)-2- aminocyclohexyl]amino}- N-{3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312056 (5-{[cis-2-Aminocyclohexyl]amino}-N-[3-carbamoyl-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311561 (2-[(2- aminoethyl)amino]-N- [3-carbamoyl-1-(2- hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311562 (2-[(2- aminoethyl)amino]-N- [1-methyl-3- (methylca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311535 (5-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311565 (2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312060 (5-{[(1R,2S)-2-Aminocyclohexyl]amino}-N-[1-(2-amino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312061 (N-{3-Carbamoyl-1-[4-(methylsulfamoyl)phenyl]-1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311532 (5-{[cis-2- aminocyclohexyl]amino}- N-{3-carbamoyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311518 (5-{[cis-3-amino-1,1- dioxidotetrahydro-2H- thiopyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311568 (2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[3-carbam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM50095468 (CHEMBL3590473 | US10155765, Example 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311566 (2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[1-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311519 (5-{[cis-4-amino-1,1- dioxidotetrahydro-2H- thiopyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311530 (5-{[cis-2- aminocyclohexyl]amino}- N-[1-methyl-3- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311522 (5-{[trans-2- aminocyclohexyl]amino}- N-(3-carbamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311524 (5-{[cis-2- aminocyclohexyl]amino}- N-[3-carbamoyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311543 (N-(3-carbamoyl-1-pyridin-4- yl-1H-pyrazol-4-yl)-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311547 (N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)pyrrolo[1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312054 (5-(((3R,4R)-4-Aminotetrahydro-2H-pyran-3-yl)amino)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311517 (5-{[(1R,2R)-2-amino- 3,3- difluorocyclohexyl]amino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311545 (N-(3-carbamoyl-1-pyridin-3- yl-1H-pyrazol-4-yl)-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311529 (N-(3-carbamoyl-1- methyl-1H-pyrazol-4- yl)-5-(pipe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311542 (N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311549 (N-(4-carbamoylpyridin-3- yl)pyrazolo[1,5- a]pyrimi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311548 (N-(3-carbamoyl-1-pyridin-3- yl-1H-pyrazol-4- yl)py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311567 (2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[1-(2- hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM312067 (N-(3-Carbamoyl-1-methyl-1H-pyrazol-4-yl)thieno[2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM50095466 (CHEMBL3590471 | US10155765, Example 12) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311528 (N-(3-carbamoyl-1- methyl-1H-pyrazol-4- yl)-5-(pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM50095463 (CHEMBL3590436 | US9649308, Example 40) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311531 (5-{[cis-2- aminocyclohexyl]amino}- N-[3- (dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311537 (N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- (cycl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311538 (N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5-[(2- h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311541 (N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- morph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311554 (N-(2-carbamoylthiophen-3- yl)pyrazolo[1,5- a]pyrim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 252 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM311555 (N-(5-tert-butyl-2- carbamoylthiophen-3- yl)pyrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 254 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp... | US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J | |||||||||||
More data for this Ligand-Target Pair |
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