Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314248 (US9611232, Example 13) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314285 (US9611232, Example 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314217 (US9611232, Example 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314284 (US9611232, Example 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314215 (US9611232, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314198 ((S)-2-(5,5-bis(4-fluorophenyl)-2-oxo-4-phenyloxazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314321 (US9611232, Example 32) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314288 (US9611232, Example 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair |