BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 3592
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM36553 (Prochelators, 3) Show SMILES CCN(C)C(=O)Oc1ccc(CN(C)CC#C)c2cccnc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM36551 (Chelator, M30 \| US9034303, M30) Show SMILES CN(CC#C)Cc1ccc(O)c2ncccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM36553 (Prochelators, 3) Show SMILES CCN(C)C(=O)Oc1ccc(CN(C)CC#C)c2cccnc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.49E+4	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rattus norvegicus (rat))	BDBM36553 (Prochelators, 3) Show SMILES CCN(C)C(=O)Oc1ccc(CN(C)CC#C)c2cccnc12 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.07E+4	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM36551 (Chelator, M30 \| US9034303, M30) Show SMILES CN(CC#C)Cc1ccc(O)c2ncccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
The Weizmann Institute of Science					More data for this Ligand-Target Pair